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Journal Article
Journal of Ethnopharmacology, ISSN 0378-8741, 04/2018, Volume 216, pp. 18 - 25
Shikonin, a naphthoquinone pigment abundant in the root of the Chinese herb , has been widely used to treat inflammatory diseases for thousands of years.... 
Aryl hydrocarbon receptor | Shikonin | Shikonin (PubChem CID:479503) | NF-E2-related factor | Drug-metabolizing enzymes | Drug transporters | KAPPA-B ACTIVATION | CHEMISTRY, MEDICINAL | HERB-DRUG | INDUCTION | CANCER | P-GLYCOPROTEIN | PLANT SCIENCES | PATHWAY | INTEGRATIVE & COMPLEMENTARY MEDICINE | GRAPEFRUIT JUICE | IN-VIVO | PHARMACOLOGY & PHARMACY | ST-JOHNS-WORT | MOLECULAR-MECHANISMS | Gene Expression Regulation, Enzymologic - drug effects | Phosphorylation | Transcriptional Activation - drug effects | Drugs, Chinese Herbal - pharmacology | Membrane Transport Proteins - drug effects | Male | RNA, Messenger - metabolism | Dose-Response Relationship, Drug | Basic Helix-Loop-Helix Transcription Factors - metabolism | Membrane Transport Proteins - genetics | Biotransformation | JNK Mitogen-Activated Protein Kinases | Receptors, Aryl Hydrocarbon - metabolism | Membrane Transport Proteins - metabolism | NF-E2-Related Factor 2 - genetics | p38 Mitogen-Activated Protein Kinases - metabolism | Hepatocytes - drug effects | Basic Helix-Loop-Helix Transcription Factors - agonists | Basic Helix-Loop-Helix Transcription Factors - genetics | Anti-Inflammatory Agents - pharmacology | RNA, Messenger - genetics | Cells, Cultured | Receptors, Aryl Hydrocarbon - genetics | Naphthoquinones - pharmacology | Extracellular Signal-Regulated MAP Kinases | Rats, Sprague-Dawley | Receptors, Aryl Hydrocarbon - agonists | Animals | NF-E2-Related Factor 2 - metabolism | Primary Cell Culture | Hepatocytes - enzymology
Journal Article
Journal Article
Journal Article
Journal of Bioenergetics and Biomembranes, ISSN 0145-479X, 10/2017, Volume 49, Issue 5, pp. 399 - 411
Journal Article
BIOCHEMICAL JOURNAL, ISSN 0264-6021, 05/2016, Volume 473, pp. 1247 - 1255
Recently, it has been found that glucagon is able to activate the beta-catenin signalling pathway leading to increased cyclin D1 and c-Myc expression in liver.... 
beta-catenin | Type 2 diabetes | protein kinase A (PKA) | niclosamide | CYCLIN D1 | PROTEIN-KINASE | BIOCHEMISTRY & MOLECULAR BIOLOGY | H89 | C-MYC | DIABETES-MELLITUS | HEPATOCELLULAR-CARCINOMA | INHIBITION | GENE | EXCESS RISK | glucagon | PRIMARY LIVER-CANCER | cancer | EXPRESSION
Journal Article