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Nature Communications, ISSN 2041-1723, 12/2017, Volume 8, Issue 1, pp. 1067 - 14
Journal Article
Cancer Research, ISSN 0008-5472, 07/2017, Volume 77, Issue 13, pp. 3513 - 3526
Journal Article
Scientific Reports, ISSN 2045-2322, 12/2018, Volume 8, Issue 1, pp. 17390 - 12
Malignant peripheral nerve sheath tumors (MPNSTs) are the leading cause of death in neurofibromatosis type 1 (NF1) patients. Current treatment modalities have... 
APOPTOSIS | IN-VITRO | PATHWAY | ER STRESS | MCL-1 | MULTIDISCIPLINARY SCIENCES | DEUBIQUITINASE INHIBITION | PROLIFERATION | BCL-2/BCL-XL | PROMOTES | PRIMES GLIOBLASTOMA CELLS | Bcl-2 protein | Therapeutic applications | Interference | Caspase | Nervous system | Recklinghausen's disease | Patients | Mcl-1 protein | Mitochondria | Cell death | Neurofibromatosis | Cell lines | Xenografts | Endoplasmic reticulum | Apoptosis | Tumors
Journal Article
Oncotarget, ISSN 1949-2553, 2017, Volume 8, Issue 18, pp. 29558 - 29573
Journal Article
Journal of Neuro-Oncology, ISSN 0167-594X, 4/2012, Volume 107, Issue 2, pp. 247 - 256
Malignant gliomas are a highly aggressive type of brain tumor with extremely poor prognosis. These tumors are highly invasive and are often surgically... 
Neurology | Medicine & Public Health | Glioma | Cell cycle | Oncology | Phosphatase | p38SJ | DING | P38SJ | CARCINOMA-CELLS | GLIOMA-CELLS | CANCER-CELLS | PHOTODYNAMIC THERAPY | CELL-CYCLE ARREST | TERMINAL KINASE | CLINICAL NEUROLOGY | GENE | ONCOLOGY | HYPERICIN | ST-JOHNS-WORT | NF-KAPPA-B | CDC2 Protein Kinase | Humans | Green Fluorescent Proteins - genetics | Extracellular Signal-Regulated MAP Kinases - metabolism | E2F Transcription Factors - metabolism | DNA-Binding Proteins - metabolism | Tetrazolium Salts | Flow Cytometry | Transfection | Time Factors | Plant Preparations - pharmacology | Thiazoles | Cyclin-Dependent Kinases | Gene Expression Regulation, Neoplastic - drug effects | Endopeptidase K - pharmacology | DNA-Binding Proteins - pharmacology | Green Fluorescent Proteins - metabolism | Ubiquitin-Protein Ligases - metabolism | DNA-Binding Proteins - genetics | Ubiquitin-Protein Ligases - pharmacology | Animals | Polycomb Repressive Complex 1 | Cell Cycle Checkpoints - drug effects | Glioblastoma - pathology | Cell Line, Tumor | Cyclin B - metabolism | Cell Proliferation - drug effects | Mice | Cyclin E - metabolism | Ubiquitin-Protein Ligases - genetics | Glioblastoma - physiopathology | Cell Line, Transformed | Hypericum - chemistry | Proteins | Neurosciences | Phosphatases | Epidermal growth factor | Growth | Gliomas | Brain tumors | Development and progression | Glioblastoma multiforme | Phosphotransferases | Tumors | Cell proliferation | Cdc2 protein | glioblastoma multiforme | Phosphorylation | Cell survival | Prognosis | Epidermal growth factor receptors | Tumor cells | Glioblastoma | Extracellular signal-regulated kinase | double prime E2F1 protein | regulatory proteins | Radiotherapy | E2F1 protein | Radiosensitizers | Signal transduction | Glioma cells | Cyclin E
Journal Article
Pathology & Oncology Research, ISSN 1219-4956, 10/2019, Volume 25, Issue 4, pp. 1659 - 1663
Glioblastoma (GB) is the most prevalent malignant primary brain tumor in adults. The preclinical glioblastoma model GL261 is widely used for investigating new... 
Biomedicine, general | Pathology | Biomedicine | Immunology | Preclinical brain tumour model | Cell cycle | Cancer Research | Oncology | Cyclin D1 | GL261 glioma | CK2 alpha prime | Cell proliferation | Brain | Protein kinase C | Animal models | Threonine | Brain tumors | Glioblastoma | Kinases | Casein kinase II | Proteins | Inhibitors | Protein-serine/threonine kinase | Adults | Tumors | Biotechnology
Journal Article
Journal Article
Journal of Molecular Medicine, ISSN 0946-2716, 10/2011, Volume 89, Issue 10, pp. 1037 - 1050
Journal Article
Neuroimage, ISSN 1053-8119, 2006, Volume 32, Issue 2, pp. 489 - 497
We utilized blood oxygenation level dependent (BOLD) functional magnetic resonance imaging (fMRI) and MR perfusion imaging methods to study the influence of... 
Prime Motor Cortex | Blood Oxygenation Level Dependent | Glioblastoma Multiforme | Relative Regional Cerebral Blood Volume | Functional Magnetic Resonance Imaging | LANGUAGE | PASSAGES | glioblastoma multiforme | PERMEABILITY | NEOPLASMS | prime motor cortex | blood oxygenation level dependent | BLOOD-FLOW | ADJACENT | HYPOXIA | IMAGE-GUIDED NEUROSURGERY | NEUROSCIENCES | NEUROIMAGING | relative regional cerebral blood volume | HIGH-RESOLUTION MEASUREMENT | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | functional magnetic resonance imaging | GRADIENT-ECHO | Image Enhancement | Humans | Middle Aged | Brain Neoplasms - physiopathology | Male | Statistics as Topic | Meningeal Neoplasms - blood supply | Hemangiopericytoma - blood supply | Brain Neoplasms - secondary | Neurons - physiology | Aged, 80 and over | Adult | Female | Neovascularization, Pathologic - physiopathology | Oligodendroglioma - blood supply | Astrocytoma - blood supply | Motor Cortex - blood supply | Magnetic Resonance Angiography | Blood Volume - physiology | Meningioma - blood supply | Oxygen - blood | Magnetic Resonance Imaging | Image Processing, Computer-Assisted | Aged | Regional Blood Flow - physiology | Glioblastoma - blood supply | Magnetic resonance imaging | Neurons | Gliomas | Brain tumors | Cancer | Brain | Nuclear magnetic resonance--NMR | Patients | Brain cancer | Surgery | Tumors
Journal Article
Oncogene, ISSN 0950-9232, 12/2011, Volume 30, Issue 49, pp. 4874 - 4886
Successful treatment of diffuse large B-cell lymphoma (DLBCL) is frequently hindered by the development of resistance to conventional chemotherapy resulting in... 
hedgehog pathway | diffuse large B-cell lymphoma | ATP-binding cassettes | GLI | ABCG2 | BIOCHEMISTRY & MOLECULAR BIOLOGY | P-GLYCOPROTEIN | CELL BIOLOGY | LUNG-CANCER | GENE | ONCOLOGY | ACUTE LYMPHOBLASTIC-LEUKEMIA | POOR RESPONSE | GENETICS & HEREDITY | NON-HODGKINS-LYMPHOMA | MULTIDRUG-RESISTANCE | EXPRESSION | CANCER RESISTANCE PROTEIN | SONIC-HEDGEHOG | Transcription, Genetic - drug effects | Hedgehog Proteins - chemistry | ATP Binding Cassette Transporter, Sub-Family G, Member 1 | Drug Tolerance - genetics | Stromal Cells - pathology | Coculture Techniques | Humans | Hedgehog Proteins - metabolism | Peptide Fragments - pharmacology | Promoter Regions, Genetic - drug effects | RNA, Messenger - metabolism | Promoter Regions, Genetic - genetics | Tumor Microenvironment - genetics | ATP-Binding Cassette Transporters - genetics | Veratrum Alkaloids - pharmacology | ATP-Binding Cassette Transporters - metabolism | Gene Expression Regulation, Neoplastic - drug effects | Binding Sites | Gene Expression Regulation, Neoplastic - genetics | Tumor Microenvironment - drug effects | Lymphoma, Large B-Cell, Diffuse - drug therapy | Lymphoma, Large B-Cell, Diffuse - pathology | RNA, Messenger - genetics | Stromal Cells - metabolism | Oncogene Proteins - metabolism | Treatment Outcome | Signal Transduction - genetics | Cinnamates - pharmacology | Signal Transduction - drug effects | Cell Line, Tumor | Trans-Activators - metabolism | Zinc Finger Protein GLI1 | Mutation | Lymphoma, Large B-Cell, Diffuse - genetics | Care and treatment | Carrier proteins | Physiological aspects | Drug targeting | Genetic aspects | Non-Hodgkin's lymphomas | Research | Drug resistance | Hedgehog proteins | Proteins | Signal transduction | Lymphomas | Cellular biology | Gene expression | Lymphocytes | Drugs | Transcription factors | double prime B-cell lymphoma | Chemoresistance | Paracrine signalling | Drug development | Doxorubicin | Lymph nodes | ABCG2 gene | Bcl-x protein | Drug tolerance | Methotrexate | Adenosine | Effusion | Tumor cells | Mortality | Survival | Promoters | Chemotherapy | Hedgehog protein | stromal cells | Site-directed mutagenesis | Microenvironments | Cancer | Peritoneum | Tumors | Index Medicus | ATP binding cassettes
Journal Article
ONCOGENE, ISSN 0950-9232, 12/2001, Volume 20, Issue 58, pp. 8326 - 8333
A large body of evidence has been, accumulated that demonstrates dominant effects of Id proteins on different aspects of cellular growth. Generally,... 
TRANSCRIPTION FACTORS | retinoblastoma protein | cell differentiation | cell cycle | angiogenesis | BIOCHEMISTRY & MOLECULAR BIOLOGY | PANCREATIC-CANCER | neuroblastoma | INHIBITOR ID2 | NEGATIVE REGULATOR | CELL BIOLOGY | LOOP-HELIX PROTEIN | ONCOLOGY | Id2 | GENETICS & HEREDITY | HUMAN FIBROBLASTS | CELL-CYCLE | DIFFERENTIATION | EXPRESSION | Multigene Family | Humans | Neoplasm Proteins - physiology | Repressor Proteins | Gene Expression Regulation, Neoplastic | Inhibitor of Differentiation Proteins | Inhibitor of Differentiation Protein 2 | Inhibitor of Differentiation Protein 1 | Neoplasms - genetics | Cell Transformation, Neoplastic - genetics | Gene Expression Regulation, Developmental | Neoplasms, Experimental - genetics | Neoplasm Proteins - genetics | Retinoblastoma Protein - physiology | Oncogenes | Cell Division - genetics | DNA-Binding Proteins - physiology | Transcription Factors - physiology | Neoplasms, Nerve Tissue - genetics | Signal Transduction | Genes, Retinoblastoma | Transcription Factors - genetics | DNA-Binding Proteins - genetics | Forecasting | Cell Division - physiology | Animals | Neovascularization, Pathologic - genetics | Neoplasm Invasiveness - genetics | Cell Cycle Proteins - physiology | Cell proliferation | double prime Id protein | Transformation | Invasiveness | Tumor cells | Malignancy | Differentiation | Cell migration | Cancer
Journal Article
Histopathology, ISSN 0309-0167, 01/2012, Volume 60, Issue 2, pp. 313 - 319
Journal Article