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Journal of Experimental Medicine, ISSN 0022-1007, 2008, Volume 205, Issue 13, pp. 2995 - 3006
Increased type I interferon (IFN-I) production and IFN-stimulated gene (ISG)expression are linked to the pathogenesis of systemic lupus erythematosus (SLE).... 
PLASMACYTOID DENDRITIC CELLS | MEDICINE, RESEARCH & EXPERIMENTAL | PRISTANE-INDUCED LUPUS | ANTIBODY-PRODUCTION | IMMUNE-COMPLEX GLOMERULONEPHRITIS | TOLL-LIKE RECEPTORS | MURINE LUPUS | RIG-I | IMMUNOLOGY | AUTOANTIBODY PRODUCTION | BALB/C MICE | IFN-ALPHA
Journal Article
Arthritis & Rheumatology, ISSN 2326-5191, 06/2017, Volume 69, Issue 6, pp. 1280 - 1293
Journal Article
by Kottyan, Leah C and Zoller, Erin E and Bene, Jessica and Lu, Xiaoming and Kelly, Jennifer A and Rupert, Andrew M and Lessard, Christopher J and Vaughn, Samuel E and Marion, Miranda and Weirauch, Matthew T and Namjou, Bahram and Adler, Adam and Rasmussen, Astrid and Glenn, Stuart and Montgomery, Courtney G and Hirschfield, Gideon M and Xie, Gang and Coltescu, Catalina and Amos, Chris and Li, He and Ice, John A and Nath, Swapan K and Mariette, Xavier and Bowman, Simon and Rischmueller, Maureen and Lester, Sue and Brun, Johan G and Gøransson, Lasse G and Harboe, Erna and Omdal, Roald and Cunninghame-Graham, Deborah S and Vyse, Tim and Miceli-Richard, Corinne and Brennan, Michael T and Lessard, James A and Wahren-Herlenius, Marie and Kvarnström, Marika and Illei, Gabor G and Witte, Torsten and Jonsson, Roland and Eriksson, Per and Nordmark, Gunnel and Ng, Wan-Fai and Anaya, Juan-Manuel and Rhodus, Nelson L and Segal, Barbara M and Merrill, Joan T and James, Judith A and Guthridge, Joel M and Scofield, R. Hal and Alarcon-Riquelme, Marta and Bae, Sang-Cheol and Boackle, Susan A and Criswell, Lindsey A and Gilkeson, Gary and Kamen, Diane L and Jacob, Chaim O and Kimberly, Robert and Brown, Elizabeth and Edberg, Jeffrey and Alarcón, Graciela S and Reveille, John D and Vilá, Luis M and Petri, Michelle and Ramsey-Goldman, Rosalind and Freedman, Barry I and Niewold, Timothy and Stevens, Anne M and Tsao, Betty P and Ying, Jun and Mayes, Maureen D and Gorlova, Olga Y and Wakeland, Ward and Radstake, Timothy and Martin, Ezequiel and Martin, Javier and Siminovitch, Katherine and Moser Sivils, Kathy L and Gaffney, Patrick M and Langefeld, Carl D and Harley, John B and Kaufman, Kenneth M and UK Primary Sjogrens Syndrome Regis and UK Primary Sjögren's Syndrome Registry and for UK Primary Sjögren's Syndrome Registry and Avdelningen för neuro- och inflammationsvetenskap and Medicinska fakulteten and Region Östergötland and Linköpings universitet and Institutionen för klinisk och experimentell medicin and Reumatologiska kliniken i Östergötland and Hjärt- och Medicincentrum
Human Molecular Genetics, ISSN 0964-6906, 01/2015, Volume 24, Issue 2, pp. 582 - 596
Journal Article
Arthritis & Rheumatology, ISSN 2326-5191, 04/2016, Volume 68, Issue 4, pp. 953 - 964
Journal Article
Clinical Immunology, ISSN 1521-6616, 2016, Volume 164, pp. 65 - 77
ABSTRACT Bruton's tyrosine kinase (Btk) is expressed in a variety of immune cells and previous work has demonstrated that blocking Btk is a promising strategy... 
Allergy and Immunology | Lupus | Interferon | TLR7 | Bruton's tyrosine kinase | RHEUMATOID-ARTHRITIS | AUTOANTIBODIES | CELLS | PRISTANE-INDUCED ARTHRITIS | MOUSE LUPUS | IMMUNOLOGY | I INTERFERON | BRUTONS TYROSINE KINASE | DISEASE | GENE-EXPRESSION | MICE | Nephritis - drug therapy | Immunosuppressive Agents | Kidney - pathology | Autoantibodies - blood | Humans | Male | Nephritis - pathology | Proteinuria - pathology | Interferon Type I - immunology | Toll-Like Receptor 7 - immunology | Lupus Erythematosus, Systemic - drug therapy | Lupus Erythematosus, Systemic - immunology | Female | Mice, Inbred DBA | Foot Joints - pathology | Macrophages - immunology | Disease Models, Animal | Foot Joints - drug effects | Protein Kinase Inhibitors - pharmacokinetics | Kidney - drug effects | Arthritis - pathology | Mice, Inbred C57BL | Animals | Proteinuria - drug therapy | Protein Kinase Inhibitors - therapeutic use | Arthritis - drug therapy | Macrophages - drug effects | Lupus Erythematosus, Systemic - chemically induced | Protein Kinase Inhibitors - pharmacology | Terpenes | Lupus Erythematosus, Systemic - pathology | Protein-Tyrosine Kinases - antagonists & inhibitors | Autoimmunity | Fc receptors | Autoantibodies | Analysis | Biological response modifiers | Tyrosine | Mortality | Arthritis | Macrophages | Immunity | Systemic lupus erythematosus | Phosphoproteins | Kidney diseases
Journal Article
Journal Article
Journal of Pharmacological Sciences, ISSN 1347-8613, 03/2017, Volume 133, Issue 3, pp. 115 - 121
Journal Article
International Immunology, ISSN 0953-8178, 10/2018, Volume 30, Issue 11, pp. 529 - 536
The transcription factor interferon regulatory factor-5 (IRF5) plays an important role in innate immune responses via the TLR-MyD88 (Toll-like receptor -... 
Toll-like receptors | autoimmune disease | interferon regulatory factor-5 | PRISTANE-INDUCED LUPUS | FAS-LIGAND | IMMUNOLOGY | PLASMACYTOID DENDRITIC CELLS | NF-KAPPA-B | PATTERN-RECOGNITION RECEPTORS | AUTOIMMUNE-DISEASE | AUTOANTIBODY PRODUCTION | T-CELLS | LYN-DEFICIENT MICE
Journal Article