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Journal Article
Progress in Molecular Biology and Translational Science, ISSN 1877-1173, 2017, Volume 152, pp. 23 - 48
Journal Article
Shengwu Gongcheng Xuebao/Chinese Journal of Biotechnology, ISSN 1000-3061, 10/2017, Volume 33, Issue 10, pp. 1665 - 1673
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 9/2014, Volume 111, Issue 35, pp. 12716 - 12721
Journal Article
Methods in Molecular Biology, ISSN 1064-3745, 2019, Volume 1864, pp. 237 - 266
Genome engineering is a biotechnological approach to precisely modify the genetic code of a given organism in order to change the context of an existing... 
DSB repair | Genome engineering | Gene targeting | Programmable nucleases | NHEJ | HDR
Journal Article
POSTEPY HIGIENY I MEDYCYNY DOSWIADCZALNEJ, ISSN 0032-5449, 09/2016, Volume 70, pp. 901 - 916
Precise and efficient genome modifications present a great value in attempts to comprehend the roles of particular genes and other genetic elements in... 
MEDICINE, RESEARCH & EXPERIMENTAL | genome editing | DNA CLEAVAGE | ZINC-FINGER NUCLEASES | CHROMOSOMAL REARRANGEMENTS | PLURIPOTENT STEM-CELLS | STREPTOCOCCUS-THERMOPHILUS | ANTIVIRAL DEFENSE | OFF-TARGET ACTIVITY | CRISPR-Cas | programmable nucleases | DUCHENNE MUSCULAR-DYSTROPHY | HOMOLOGOUS RECOMBINATION | CONDITIONAL ALLELES
Journal Article
2019, Advances in Experimental Medicine and Biology, Volume 1144, 16
Sickle cell disease (SCD) is an inherited monogenic disorder resulting in serious mortality and morbidity worldwide. Although the disease was characterized... 
PROGENITOR CELLS | MEDICINE, RESEARCH & EXPERIMENTAL | Hemoglobinopathies | ERYTHROID ENHANCER | DUAL-RNA | BCL11A | Gene editing | BONE-MARROW-TRANSPLANTATION | CELL BIOLOGY | DELIVERY-SYSTEM | CRISPR-CAS9 NUCLEASES | FETAL-HEMOGLOBIN | BIOLOGY | Programmable endonucleases | HEALTH-CARE | Gene therapy | Hematopoietic stem cell transplantation | HEMATOPOIETIC STEM
Book Chapter
Postępy Higieny i Medycyny Doświadczalnej, ISSN 0032-5449, 09/2016, Volume 70, pp. 901 - 916
Precise and efficient genome modifications present a great value in attempts to comprehend the roles of particular genes and other genetic elements in... 
CRISPR-Cas | programowane nukleazy | Genome editing | programmable nucleases | edycja genomu
Journal Article
Methods in Molecular Biology, ISSN 1064-3745, 2017, Volume 1630, pp. 141 - 152
Gene-modified monkey models would be particularly valuable in biomedical and neuroscience research. Virus-based transgenic and programmable nucleases-based... 
Transgenic | Programmable nucleases | Lentivirus | Knockout | Gene-modified monkeys | Animals | Gene Editing - veterinary | Animals, Genetically Modified | CRISPR-Cas Systems | Female | Gene Editing - methods | Endonucleases - metabolism | Sperm Injections, Intracytoplasmic - veterinary | Gene Knockout Techniques | Haplorhini - genetics | Index Medicus
Journal Article
PLoS ONE, ISSN 1932-6203, 02/2016, Volume 11, Issue 2, pp. e0149379 - e0149379
Journal Article
Plant Biotechnology Journal, ISSN 1467-7644, 02/2016, Volume 14, Issue 2, pp. 448 - 462
Targeted genome‐editing technology using designed nucleases has been evolving rapidly, and its applications are widely expanding in research, medicine and... 
homology‐directed repair | double‐strand break | transcription activator‐like effector nuclease | CRISPR‐Cas9 | zinc‐finger nuclease | nonhomologous end‐joining | Zinc-finger nuclease | Transcription activator-like effector nuclease | Nonhomologous end-joining | Double-strand break | CRISPR-Cas9 | Homology-directed repair | CRISPR-CAS SYSTEMS | PLANT-CELLS | DOUBLE-STRAND BREAKS | ZINC-FINGER NUCLEASES | DNA-BINDING SPECIFICITY | PROGRAMMABLE NUCLEASES | PLANT SCIENCES | PLURIPOTENT STEM-CELLS | transcription activator-like effector nuclease | zinc-finger nuclease | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | nonhomologous end-joining | GENE-EXPRESSION | double-strand break | RNA-GUIDED ENDONUCLEASES | homology-directed repair | Genetic Engineering | Base Sequence | DNA Repair - genetics | Endonucleases - metabolism | Genome, Plant | DNA Breaks, Double-Stranded | Gene Editing | Genetic research | Nucleases | DNA binding proteins | Genomics | Plant genetics | Editing | DNA repair | Genomes | CRISPR | Biotechnology | Transcription | Homology | Research | Ribonucleic acid--RNA | Gene expression | Zinc | Gene sequencing | Efficiency | Technology | Cell cycle | Stem cells | Non-homologous end joining | Genetic engineering | Mutation | Repair | Chromosomes | Deoxyribonucleic acid--DNA | Methods | Technology utilization | Index Medicus | Breaking | Bacteria | Nuclease
Journal Article