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Environmental Health Perspectives, ISSN 0091-6765, 8/2011, Volume 119, Issue 8, pp. 1142 - 1148
Background: The large and increasing number of chemicals released into the environment demands more efficient and cost-effective approaches for assessing... 
Chemical hazards | Receptors | Genomics | Environmental health | Agonists | Ligands | Cytotoxicity | Libraries | Environmental agencies | Research | Nuclear receptors | Chemical genomics | qHTS | Assay performance | Tox21 | assay performance | TOXICITY | ANTAGONISM | IDENTIFICATION | ESTROGEN-RECEPTOR | nuclear receptors | ENVIRONMENTAL SCIENCES | IN-VITRO | PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH | EVOLUTION | DISEASE | ASSAYS | SUPERFAMILY | HEALTH | chemical genomics | cytotoxicity | Peroxisome Proliferator-Activated Receptors - agonists | Cell Line | Retinoid X Receptor alpha - metabolism | Peroxisome Proliferator-Activated Receptors - antagonists & inhibitors | Humans | Orphan Nuclear Receptors - agonists | Receptors, Androgen - metabolism | Receptors, Cytoplasmic and Nuclear - agonists | Orphan Nuclear Receptors - metabolism | PPAR gamma - metabolism | Receptors, Thrombin - antagonists & inhibitors | Retinoid X Receptor alpha - agonists | Fragile X Mental Retardation Protein | Orphan Nuclear Receptors - antagonists & inhibitors | Retinoid X Receptor alpha - antagonists & inhibitors | PPAR gamma - antagonists & inhibitors | Receptors, Thrombin - agonists | Liver X Receptors | Receptors, Cytoplasmic and Nuclear - antagonists & inhibitors | Peroxisome Proliferator-Activated Receptors - metabolism | Receptors, Thrombin - metabolism | Estrogen Receptor alpha - metabolism | Environmental Pollutants - toxicity | Receptors, Cytoplasmic and Nuclear - metabolism | Environmental aspects | Physiological aspects | Cell receptors | Health aspects | Chemicals | Index Medicus
Journal Article
British Journal of Pharmacology, ISSN 0007-1188, 08/2012, Volume 166, Issue 8, pp. 2289 - 2306
Journal Article
European Journal of Cancer, ISSN 0959-8049, 2005, Volume 41, Issue 10, pp. 1487 - 1494
We have investigated the presence of oestrogen receptor-related (ERR) mRNA in human colorectal tumour tissues and adjacent normal mucosa by reverse... 
Tumour progression | Peroxisome proliferator-activated receptor γ coactivator-1 | Oestrogen receptor beta | Peroxisome proliferator-activated receptor γ | Oestrogen receptor-related receptor | Colorectal carcinoma | Oestrogen receptor alpha | GAMMA | CELLS | tumour progression | peroxisome proliferator-activated receptor gamma coactivator-1 | oestrogen receptor beta | SUBTYPES | TRANSCRIPTION | oestrogen receptor alpha | oestrogen receptor-related receptor | colorectal carcinoma | COLON-CANCER | BREAST-CANCER | MUCOSA | ONCOLOGY | COACTIVATOR PGC-1 | MICE | peroxisome proliferator-activated receptor gamma | BINDING | Gene Expression | Receptors, Estrogen - metabolism | Receptors, Estrogen - genetics | Colorectal Neoplasms - genetics | Humans | Middle Aged | Male | Receptors, Cytoplasmic and Nuclear - genetics | PPAR gamma - metabolism | RNA, Messenger - metabolism | Disease Progression | Estrogen Receptor beta - metabolism | Transcription Factors - metabolism | Estrogen Receptor alpha - genetics | Estrogen Receptor beta - genetics | Reverse Transcriptase Polymerase Chain Reaction - methods | Aged, 80 and over | Estrogen Receptor alpha - metabolism | Female | Aged | Colorectal Neoplasms - metabolism | Receptors, Cytoplasmic and Nuclear - metabolism | Messenger RNA | Reverse transcriptase | Analysis | Gastrointestinal diseases | Estrogen | Colorectal cancer | Development and progression | Gene expression | Tumors | Index Medicus
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 08/2015, Volume 290, Issue 32, pp. 19544 - 19557
Peroxisome proliferator-activated receptor gamma (PPAR gamma) ligands have been widely used to treat type 2 diabetes mellitus. However, knowledge of PPAR gamma... 
DIABETES-MELLITUS | RETINOIC ACID | GLUCOSE-METABOLISM | FREE FATTY-ACIDS | BIOCHEMISTRY & MOLECULAR BIOLOGY | INSULIN-SECRETION | ENDOTHELIAL-CELLS | KINASE | P38 MAPK | COACTIVATOR PGC-1-ALPHA | DEPENDENT MANNER | Sirtuin 1 - metabolism | RNA, Small Interfering - genetics | Luciferases - metabolism | Receptors, G-Protein-Coupled - metabolism | Humans | E1A-Associated p300 Protein - genetics | E1A-Associated p300 Protein - metabolism | PPAR gamma - metabolism | Sirtuin 1 - genetics | Luciferases - genetics | Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha | Transcription, Genetic | p38 Mitogen-Activated Protein Kinases - metabolism | Thiazolidinediones - pharmacology | Genes, Reporter | PPAR gamma - genetics | Cell Line | Receptor Cross-Talk | Endothelial Cells - metabolism | Gene Expression Regulation | p38 Mitogen-Activated Protein Kinases - genetics | Signal Transduction - genetics | DNA - metabolism | Transcription Factors - genetics | Hypoglycemic Agents - pharmacology | DNA - genetics | Transcription Factors - metabolism | Endothelial Cells - cytology | p38 Mitogen-Activated Protein Kinases - antagonists & inhibitors | Protein Binding | Ligands | Receptors, G-Protein-Coupled - genetics | Primary Cell Culture | Endothelial Cells - drug effects | RNA, Small Interfering - metabolism | Index Medicus | peroxisome proliferator-activated receptor (PPAR) | thiazolidinedione | G protein-coupled receptor 40 (GPR40) | Signal Transduction | E1A-binding protein p300 (P300) | sirtuin 1 (SIRT1) | G protein-coupled receptor (GPCR) | peroxisome proliferator-activated receptor gamma coactivator 1-alpha (PGC-1a)(PPARGC1A) | peroxisome proliferator-activated receptor gamma (PPARgamma) | p38 MAPK
Journal Article
Journal of Experimental Medicine, ISSN 0022-1007, 04/2001, Volume 193, Issue 7, pp. 827 - 838
Journal Article
Diabetes, ISSN 0012-1797, 06/2006, Volume 55, Issue 6, pp. 1783 - 1791
Evidence for a Mitochondrial Regulatory Pathway Defined by Peroxisome Proliferator–Activated Receptor-γ Coactivator-1α, Estrogen-Related Receptor-α, and... 
COX-II, cytochrome c oxidase subunit-II | Mfn2, mitofusin 2 | PGC, peroxisome proliferator-activated receptor-γ coactivator | MEF2, myocyte enhancer factor-2 | Errα, estrogen-related receptor-α | 2A GENE | HEPATIC GLUCONEOGENESIS | BIOGENESIS | ERR-ALPHA | PGC-1-ALPHA | ENDOCRINOLOGY & METABOLISM | GENE-EXPRESSION | PGC-1 | TRANSCRIPTIONAL COACTIVATOR | ENERGY-METABOLISM | HUMAN SKELETAL-MUSCLE | GTP Phosphohydrolases | Gene Expression - drug effects | Rats, Wistar | Humans | Mitochondria, Muscle - metabolism | Male | Muscle, Skeletal - metabolism | Mitochondrial Proteins - genetics | Muscle, Skeletal - cytology | RNA, Messenger - metabolism | Heat-Shock Proteins - genetics | Transfection | Chromatin Immunoprecipitation | Mitochondrial Proteins - metabolism | Muscle, Skeletal - drug effects | Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha | Dioxoles - pharmacology | Estrogen Receptor alpha - metabolism | Electrophoretic Mobility Shift Assay | Membrane Proteins - metabolism | Cold Temperature | Membrane Proteins - genetics | Heat-Shock Proteins - metabolism | RNA, Messenger - genetics | Cells, Cultured | Rats | Signal Transduction - genetics | Transcription Factors - genetics | Blotting, Western | Transcription Factors - metabolism | Animals | Estrogen Receptor alpha - genetics | Signal Transduction - drug effects | Protein Binding | Signal Transduction - physiology | Adipose Tissue, Brown - drug effects | Adipose Tissue, Brown - metabolism | Mice | HeLa Cells | Index Medicus | Abridged Index Medicus
Journal Article
Toxicology and Applied Pharmacology, ISSN 0041-008X, 04/2014, Volume 276, Issue 1, pp. 73 - 81
Although non-alcoholic fatty liver disease (NAFLD) is currently the most common form of chronic liver disease there is no pharmacological agent approved for... 
Fatty acid oxidation | Hepatocytes | Non-alcoholic steatohepatitis | Hepatotoxicity | Fatty acid overload | BETA-OXIDATION | GAMMA | CYTOCHROMES P450 | FATTY LIVER-DISEASE | NUCLEAR RECEPTORS | NONALCOHOLIC STEATOHEPATITIS | RECEPTOR-ALPHA/GAMMA AGONIST | BODY-FAT | IN-VITRO | PHARMACOLOGY & PHARMACY | TOXICOLOGY | HEPATIC STEATOSIS | Glycine - analogs & derivatives | Humans | Oleic Acid - adverse effects | Orphan Nuclear Receptors - metabolism | PPAR gamma - metabolism | Liver - drug effects | Liver X Receptors | Non-alcoholic Fatty Liver Disease | Drug Evaluation, Preclinical | Fatty Acids, Nonesterified - adverse effects | Peroxisome Proliferator-Activated Receptors - agonists | Cell Line | Fatty Liver - metabolism | Oxidation-Reduction | Liver - metabolism | Receptors, Cytoplasmic and Nuclear - genetics | Orphan Nuclear Receptors - genetics | Fatty Liver - drug therapy | Triglycerides - metabolism | Gene Expression Regulation - drug effects | Orphan Nuclear Receptors - antagonists & inhibitors | Glycine - pharmacology | Lipogenesis - drug effects | Receptors, Cytoplasmic and Nuclear - antagonists & inhibitors | Lipid Metabolism - drug effects | PPAR gamma - agonists | Peroxisome Proliferator-Activated Receptors - metabolism | Lipotropic Agents - pharmacology | PPAR alpha - agonists | Oxazoles - pharmacology | PPAR alpha - metabolism | Receptors, Cytoplasmic and Nuclear - metabolism | Monounsaturated fatty acids | Triglycerides | Index Medicus | Oleic Acid | Liver | Gene Expression Regulation | PPAR alpha | Lipid Metabolism | Pharmacology | Glycine | PPAR gamma | Receptors, Cytoplasmic and Nuclear | Fatty Liver | Life Sciences | Oxazoles | Peroxisome Proliferator-Activated Receptors | Fatty Acids, Nonesterified | Lipotropic Agents | Orphan Nuclear Receptors | Lipogenesis | Pharmaceutical sciences | OXIDATION | TRIGLYCERIDES | IN VIVO | PATHOLOGY | 60 APPLIED LIFE SCIENCES | OLEIC ACID | DISEASES | METABOLISM | IN VITRO | GENES | LIVER | LIVER CELLS | RECEPTORS
Journal Article
Journal Article
Journal of Neurochemistry, ISSN 0022-3042, 08/2014, Volume 130, Issue 4, pp. 563 - 574
Journal Article
NeuroReport, ISSN 0959-4965, 01/2019, Volume 30, Issue 1, p. 32
Palmitoylethanolamine (PEA) is a ligand at peroxisome proliferator-activated receptors-[alpha] (PPAR[alpha]), a nuclear receptor that has anti-inflammatory... 
Nociception | Rats | Peroxisomes | Research | Rattus
Journal Article
Journal Article