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promoter-context (124) 124
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DIABETES, ISSN 0012-1797, 12/2013, Volume 62, Issue 12, pp. 4098 - 4108
The beneficial metabolic actions of estrogen-based therapies are mainly mediated by estrogen receptor (ER), a nuclear receptor that regulates gene... 
GLUCOSE-HOMEOSTASIS | METABOLIC SYNDROME | AF-2 | PROMOTER-CONTEXT | ENDOCRINOLOGY & METABOLISM | MICE | DOMAINS | CELL | RECEPTOR-ALPHA ACTIVATION | ADIPOSE-TISSUE | BETA
Journal Article
Endocrinology, ISSN 0013-7227, 2019, Volume 160, Issue 4, pp. 759 - 769
One in eight women will be diagnosed with breast cancer in their lifetime. Because estrogen receptor-alpha (ER alpha) is expressed in similar to 70% of... 
DEGRADER SERD | BAZEDOXIFENE | PROMOTER-CONTEXT | ESTROGEN-RECEPTOR-ALPHA | TAMOXIFEN RESISTANCE | GROWTH | ENDOCRINOLOGY & METABOLISM | MUTATIONS | NF-KAPPA-B | BINDING | TUMORS
Journal Article
PLANT CELL, ISSN 1040-4651, 06/2019, Volume 31, Issue 6, pp. 1276 - 1288
Seed dormancy governs the timing of germination, one of the most important developmental transitions in a plant's life cycle. The DELAY OF GERMINATION1 (DOG1)... 
KEY REGULATOR | BIOCHEMISTRY & MOLECULAR BIOLOGY | MATURATION | LOW-TEMPERATURE | PLANT SCIENCES | CELL BIOLOGY | EMBRYO DEVELOPMENT | LEAFY COTYLEDON1 | PROMOTER CONTEXT | ABI5 | THALIANA | DOG1 | GENE-EXPRESSION
Journal Article
BBA - Gene Regulatory Mechanisms, ISSN 1874-9399, 04/2019, Volume 1862, Issue 4, pp. 522 - 533
The activation functions AF1 and AF2 of nuclear receptors mediate the recruitment of coregulators in gene regulation. AF1 is mapped to the highly variable and... 
Coregulators | Activation function 1 | Progesterone receptor | Transcriptional activity | Positively charged residues | TERMINAL DOMAIN | NUCLEAR RECEPTORS | BIOCHEMISTRY & MOLECULAR BIOLOGY | ALPHA | BREAST-CANCER CELLS | INTRINSICALLY DISORDERED PROTEINS | RETINOIC ACID | BIOPHYSICS | PROMOTER-CONTEXT | CO-REPRESSOR | ESTROGEN PLUS PROGESTIN | NF-KAPPA-B
Journal Article
Journal Article
CLINICAL BREAST CANCER, ISSN 1526-8209, 10/2017, Volume 17, Issue 6, pp. 403 - 407
According to the World Health Organization (WHO) published data in 2015; breast cancer is the most prevalent and the second leading cause of cancer death among... 
POSSIBLE MECHANISMS | OVERCOMING STRATEGIES | Breast cancer | Molecular network | ENDOCRINE THERAPY RESISTANCE | ER-alpha 36 | VARIANT | Cytosolic growth cascades | ER-ALPHA | BREAST-CANCER CELLS | ONCOLOGY | Tamoxifen resistance | PROMOTER-CONTEXT | ESTROGEN-RECEPTOR-ALPHA | ANTIESTROGEN RESISTANCE | EXPRESSION
Journal Article
Journal Article
Science, ISSN 0036-8075, 3/2002, Volume 295, Issue 5564, pp. 2465 - 2468
Selective estrogen receptor modulators (SERMs) mimic estrogen action in certain tissues while opposing it in others. The therapeutic effectiveness of SERMs... 
Neuroscience | Transfection | RNA | Genes | Cell lines | Small interfering RNA | Phenols | Reports | Breast cancer | Selective estrogen receptor modulators | Endometrial neoplasms | HUMAN ESTROGEN-RECEPTOR | ACTIVATION | COACTIVATOR | ANTIESTROGEN | GENE | PROMOTER-CONTEXT | MULTIDISCIPLINARY SCIENCES | TRANSCRIPTION | C-MYC | 4-HYDROXYTAMOXIFEN | CANCER | Raloxifene Hydrochloride - pharmacology | Receptors, Estrogen - metabolism | Histone Acetyltransferases | Humans | Endometrial Neoplasms - metabolism | Endometrium - drug effects | Insulin-Like Growth Factor I - genetics | Genes, myc | Breast - metabolism | Breast Neoplasms - metabolism | DNA-Binding Proteins - metabolism | Endometrial Neoplasms - genetics | Female | Transcription, Genetic | Tumor Cells, Cultured | Estradiol - pharmacology | Repressor Proteins - metabolism | Endometrium - metabolism | Tamoxifen - metabolism | Promoter Regions, Genetic | Response Elements | Gene Silencing | Histone Deacetylases - metabolism | Transcription Factors - genetics | Organ Specificity | Selective Estrogen Receptor Modulators - metabolism | Gene Expression Regulation - drug effects | Transcription Factors - metabolism | Raloxifene Hydrochloride - metabolism | Breast Neoplasms - genetics | Receptors, Estrogen - chemistry | Cell Cycle | Breast - drug effects | Tamoxifen - pharmacology | Nuclear Receptor Coactivator 1 | Selective Estrogen Receptor Modulators - pharmacology | Raloxifene | Tamoxifen | Drug therapy | Health aspects | Tissue | Molecules | Estrogen
Journal Article
Nature Communications, ISSN 2041-1723, 12/2018, Volume 9, Issue 1, pp. 2368 - 12
Journal Article