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Journal Article
Cell, ISSN 0092-8674, 2003, Volume 115, Issue 1, pp. 61 - 70
Tumor necrosis factor (TNFα) receptor signaling can simultaneously activate caspase 8, the transcription factor, NF-κB and the kinase, JNK. While activation of... 
INDUCED CELL-DEATH | CYTOCHROME-C | INHIBITION | PROTEIN | BIOCHEMISTRY & MOLECULAR BIOLOGY | MITOCHONDRIA | INDUCTION | NF-KAPPA-B | CASPASE ACTIVATION | PROMOTES | SIGNAL-TRANSDUCTION PATHWAY | CELL BIOLOGY
Journal Article
EMBO reports, ISSN 1469-221X, 09/2014, Volume 15, Issue 9, pp. 982 - 990
Journal Article
Molecular Cell, ISSN 1097-2765, 11/2016, Volume 64, Issue 4, pp. 803 - 814
Mitochondrial p53 is involved in apoptosis and tumor suppression. However, its regulation is not well studied. Here, we show that TRAF6 E3 ligase is a crucial... 
p53 mitochondrial translocation | tumor suppression | TRAF6 inhibits apoptosis | colorectal cancer | p300 recruitment | K63-linked ubiquitination of p53 | p53 K24 ubiquitination | genotoxic stress | MCL1/BaK | p53 transactivation | UBIQUITINATION | MDM2-DEFICIENT MICE | ACTIVATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | IN-VIVO | EMBRYONIC LETHALITY | DEGRADATION | BAK | NF-KAPPA-B | PROMOTES | MEMBRANE PERMEABILIZATION | CELL BIOLOGY | Neoplasm Transplantation | Colonic Neoplasms - genetics | Tumor Suppressor Protein p53 - antagonists & inhibitors | Colonic Neoplasms - drug therapy | Humans | Cytosol - drug effects | E1A-Associated p300 Protein - genetics | Gene Expression Regulation, Neoplastic | Myeloid Cell Leukemia Sequence 1 Protein - metabolism | bcl-2 Homologous Antagonist-Killer Protein - genetics | Apoptosis - genetics | Antineoplastic Agents - therapeutic use | E1A-Associated p300 Protein - metabolism | bcl-2 Homologous Antagonist-Killer Protein - metabolism | Tumor Suppressor Protein p53 - genetics | Ubiquitination | Cell Nucleus - metabolism | Lysine - metabolism | TNF Receptor-Associated Factor 6 - genetics | Colonic Neoplasms - mortality | Signal Transduction | Tumor Suppressor Protein p53 - metabolism | Mitochondria - metabolism | Mitochondria - drug effects | Sulfonamides - pharmacology | Myeloid Cell Leukemia Sequence 1 Protein - genetics | Protein Transport | Xenograft Model Antitumor Assays | Animals | Colonic Neoplasms - pathology | Survival Analysis | TNF Receptor-Associated Factor 6 - metabolism | Cell Line, Tumor | Cytosol - metabolism | Mice | Cell Nucleus - drug effects | Ubiquitin | Medical colleges | Chemotherapy | Ligases | Colorectal cancer | Tumor proteins | Drug resistance | Cancer | Apoptosis | Yuan (China) | Index Medicus
Journal Article
Journal Article
Apoptosis, ISSN 1360-8185, 02/2019, Volume 24, Issue 1-2, pp. 108 - 118
Journal Article
Journal Article
BBA - General Subjects, ISSN 0304-4165, 12/2014, Volume 1840, Issue 12, pp. 3374 - 3384
Gambogic acid is a potent anticancer agent and has been found effective against various types of cancer cells. The present study was addressed to explore the... 
Gambogic acid | Bladder cancer | Autophagy | p62 | Apoptosis | BIOCHEMISTRY & MOLECULAR BIOLOGY | DEATH | MITOCHONDRIAL-MEMBRANE | SELECTIVE AUTOPHAGY | IN-VITRO | ANTIAPOPTOTIC PROTEINS | INHIBITION | BIOPHYSICS | DEGRADATION | CROSSTALK | PROMOTES | LYMPHOMA HUT-78 | Cancer cells
Journal Article