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Journal of Biochemistry, ISSN 0021-924X, 2/2009, Volume 145, Issue 2, pp. 161 - 168
Here, we show that three enzymes belonging to the 1B group of the aldo-keto reductase (AKR) superfamily, i.e., human placental aldose reductase (AKR1B1), mouse... 
Sorbinil | Prostaglandin F | reductase | Tolrestat | Prostaglandin H
Journal Article
03/2012
Endogenous brain compounds and xenobiotics, including the neurotoxins such as the amphetamine analogs 3,4-methylenedioxymethamphetamine (MDMA,Ecstasy),... 
fetal toxicity | neurotoxicity | in utero exposure | Nrf2 | methamphetamine | 0383 | cyclooxygenase | 0419 | 0307 | prostaglandin H synthase | oxidative stress | 0317
Dissertation
Endocrinology, ISSN 0013-7227, 2019, Volume 160, Issue 2, pp. 249 - 275
Despite decades of research in the field of human reproduction, the mechanisms responsible for human parturition still remain elusive. The objective of this... 
PROSTAGLANDIN-H-SYNTHASE | PLACENTA | ENDOCRINOLOGY & METABOLISM | TUMOR-SUPPRESSOR | RECEPTOR | GROWTH-FACTOR | MICRORNAS | FETAL | EXPRESSION | CANCER | DEHYDROGENASE
Journal Article
Inflammation and Allergy - Drug Targets, ISSN 1871-5281, 12/2015, Volume 14, Issue 1, pp. 19 - 28
In a recent work, we described the design and synthesis of arylnitroalkenes, able to scavenge macrophagederived oxidants, in particular peroxynitrite and... 
Antioxidants | Analgesia | Prostaglandin H synthase inhibitors | Inflammation | Anti-inflammatory therapy
Journal Article
by Wang, WS and Chen, ZJ and Myatt, L and Sun, K
ENDOCRINE REVIEWS, ISSN 0163-769X, 06/2018, Volume 39, Issue 3, pp. 241 - 260
Journal Article
Journal of Proteomics, ISSN 1874-3919, 06/2012, Volume 75, Issue 11, pp. 3240 - 3247
Although renal histopathology is the gold standard for the diagnosis and prognosis of lupus nephritis (LN), the invasiveness of renal biopsy warrants the... 
Urine | Biomarker | Proteomics | Zn-α2-glycoprotein | Lupus nephritis | D-isomerase | Prostaglandin H
Journal Article
Biochemical and Biophysical Research Communications, ISSN 0006-291X, 2010, Volume 395, Issue 2, pp. 168 - 172
Prostaglandin H not only serves as the common precursor of all other PGs, but also directly triggers signals (e.g. platelet aggregation), depending on its... 
Prostaglandin H 2 | Prostaglandin transporter | Kinetics
Journal Article
TETRAHEDRON LETTERS, ISSN 0040-4039, 10/2016, Volume 57, Issue 41, pp. 4537 - 4540
Soybean lipoxygenase-1 (SLO-1) catalyzes the C-H abstraction from the reactive carbon (C-11) in linoleic acid as the first and rate-determining step in the... 
CATALYSIS | Hydrogen tunneling | CHEMISTRY, ORGANIC | SOYBEAN LIPOXYGENASE-1 | Linoleic acid | PROTEIN DYNAMICS | POSITION | PROSTAGLANDIN-H-SYNTHASE | SPECTROSCOPY | SUBSTRATE | Secondary isotope effects | ARACHIDONIC ACIDS | Lipoxygenase
Journal Article
FEBS LETTERS, ISSN 0014-5793, 10/2012, Volume 586, Issue 20, pp. 3723 - 3730
Prostaglandin (PG) H synthases (PGHS) or cyclooxygenases (COX) catalyse the peroxidation of arachidonic acid (AA) to PGG(2) and PGH(2) which are further... 
Oxidative stress | Biomarker | HUMAN-DISEASE | VIVO | PEROXYNITRITE | ISOPROSTANE | BIOCHEMISTRY & MOLECULAR BIOLOGY | Arachidonic acid | CHROMATOGRAPHY | CELL BIOLOGY | 8-EPI-PROSTAGLANDIN F-2 ALPHA | Cyclooxygenase | IN-VITRO | F-2-ISOPROSTANES | BIOPHYSICS | BIOSYNTHESIS | Glutathione | Prostaglandin H synthase
Journal Article
Journal Article
JOURNAL OF EXPERIMENTAL MEDICINE, ISSN 0022-1007, 07/2004, Volume 200, Issue 1, pp. 69 - 78
The established model for the mechanism of action of aspirin is the inhibition of prostaglandin synthesis. However, this has never fully explained aspirin's... 
LIPOXIN A | MEDICINE, RESEARCH & EXPERIMENTAL | ENDOTHELIAL CELL-ADHESION | NO-RELEASING ASPIRIN | epi-lipoxins | DEFICIENT MICE | IMMUNOLOGY | resolution | PROSTAGLANDIN-H SYNTHASE | microvascular endothelium | CARRAGEENAN-INDUCED PLEURISY | leukocyte trafficking | nonsteroidal antiinflammatory drugs | LEUKOCYTE ADHESION | NF-KAPPA-B | STABLE ANALOGS
Journal Article
Journal of the American Chemical Society, ISSN 0002-7863, 01/2018, Volume 140, Issue 1, pp. 235 - 243
Journal Article
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