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science & technology (64) 64
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Journal Article
Tetrahedron letters, ISSN 0040-4039, 04/2012, Volume 53, Issue 14, pp. 1695 - 1698
Neuroprotectin D1/Protectin D1, a potent anti-inflammatory, proresolving, and neuroprotective lipid mediator derived biosynthetically from docosahexaenoic acid, was prepared in an enantiomerically... 
Neuroprotectin D1/protectin D1 | Aspirin | Docosahexaenoic acid | Anti-inflammatory | Total synthesis | Unsaturated fatty acids | Synthesis | Analgesics | Chemical synthesis | Fatty acids | Omega-3 fatty acids | Organic compounds | Synthesis (chemistry) | Precursors | Olefins | Isomerization | Lipids | Strategy | Alkynes | Protectin D1 | Neuroprotectin D1
Journal Article
Molecular medicine reports, ISSN 1791-2997, 04/2016, Volume 13, Issue 4, pp. 3627 - 3638
Journal Article
Journal of inflammation research, ISSN 1178-7031, 08/2017, Volume 10, pp. 119 - 133
.... The effects of Rvs E1 and D1 and protectin DX (PDX) were assessed in rat paws inflamed by the standard proinflammatory stimulus carrageenan or by histamine, 5-hydroxytryptamine, substance P or prostaglandin E... 
Nociception | Antiinflammatory drugs | Edema | Analgesics | Specialized pro-resolving lipid mediators | Pain | Animals | Ethanol | Inflammation | Experiments | Fatty acids | nociception | edema | resolvin E1 | protectin DX | resolvin D1
Journal Article
The Journal of surgical research, ISSN 0022-4804, 01/2019, Volume 233, pp. 104 - 110
.... We evaluated the influence of two specialized proresolving mediators, resolvin D1 (RvD1) and protectin D1 isomer (PD1 iso... 
Protectin D1 isomer | ω-3 fatty acid | Inflammation | Neointimal hyperplasia | Resolvin D1 | Atherosclerosis | Life Sciences & Biomedicine | Surgery | Science & Technology | Transluminal angioplasty | Enzymes | Medical colleges | Hyperplasia | B cells | Macrophages | Fatty acids | Index Medicus
Journal Article
Biochimie, ISSN 0300-9084, 04/2014, Volume 99, Issue 1, pp. 1 - 7
.... Among them, protectin D1 (PD1), an endogenous dihydroxylated and non-cyclic docosatriene made through lipoxygenation and hydrolysis of an epoxide intermediate, shows appealing biological effects... 
Protectin | Inflammation | Maresin | Docosatrienes | PUFA metabolites | Life Sciences & Biomedicine | Biochemistry & Molecular Biology | Science & Technology | Animals | Hydroxylation | Docosahexaenoic Acids - physiology | Stereoisomerism | Humans | Hydrolysis | Unsaturated fatty acids | Metabolites | Diastereomers | Omega-3 fatty acids | Index Medicus | Organic chemistry | Chemical Sciences
Journal Article
Tetrahedron letters, ISSN 0040-4039, 2011, Volume 52, Issue 23, pp. 3001 - 3004
Stereoselective total synthesis of protectin D1 was completed through construction of the Z, E, E-triene structure by using the Suzuki coupling between the vinyl borane (C13–C22... 
Suzuki coupling | Protectin D1 | Antiinflammation | Synthesis | Asymmetric epoxidation | Anti-inflammatory drugs | Organic compounds | Synthesis (chemistry) | Iodides | Precursors | Tetrahedrons | Optical activity | Boranes | Joining | Acetylene
Journal Article
Tetrahedron letters, ISSN 0040-4039, 10/2014, Volume 55, Issue 43, pp. 6011 - 6015
The total synthesis of the potent anti-inflammatory lipid mediator Protectin D1 derived from docosahexaenoic acid, has been achieved... 
Wittig reaction | Sonogashira coupling | Takai olefination | Protectin D1/Neuroprotectin D1 | Inflammation resolution | Total synthesis | Anti-inflammatory drugs | Synthesis | Organic compounds | Silver | Synthesis (chemistry) | Tetrahedrons | Lipids | Strategy | Joining | Docosahexaenoic acid | Pools
Journal Article
Revista clínica de periodoncia, implantología y rehabilitación oral, ISSN 0718-5391, 12/2016, Volume 9, Issue 3, pp. 231 - 237
En la actualidad existe consenso en que el daño de los tejidos de soporte dentario que se produce durante la periodontitis es un proceso complejo en el cual la... 
Enfermedad periodontal | Periodontal disease | Péptido antimicrobiano | Protectin D1 | Resolvina D1 | Protectina D1 | Resolvin D1 | Antimicrobial peptide
Journal Article
Prostaglandins & other lipid mediators, ISSN 1098-8823, 11/2017, Volume 133, pp. 103 - 110
[Display omitted] •Uncontrolled, excessive acute and chronic unresolved inflammation can result in the development of several human diseases.•Lipoxygenases and... 
Protectin D1n-3 DPA | n-3 Docosapentaenoic acid | Lipoxygenase | Human leukocytes | Anti-inflammatory | Specialized pro-resolving mediators | Pro-resolution | Protectin D1 | Index Medicus | pro-resolution | lipoxygenase | human leukocytes | protectin D1n-3 DPA | specialized pro-resolving mediators | anti-inflammatory | n-3 docosapentaenoic acid
Journal Article