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Molecular neurobiology, ISSN 0893-7648, 2013, Volume 47, Issue 2, pp. 613 - 621
.... Many lines of evidence indicate that permeabilization of cellular membranes by amyloid oligomers may be the key factor in disrupting cellular homeostasis... 
Leakage | Neurology | Permeabilization | Neurosciences | Biomedicine | Neurobiology | Fluorescence | Membrane | Lipids | Oligomer | Pore formation | Cell Biology | Animals | Amyloid - metabolism | Humans | Lipid Metabolism | Amyloid - chemistry | Lipid Bilayers - chemistry | Lipid Bilayers - metabolism | alpha-Synuclein - metabolism | Protein Binding - physiology | alpha-Synuclein - chemistry | Amyloid
Journal Article
Journal of the American Chemical Society, ISSN 0002-7863, 04/2016, Volume 138, Issue 13, pp. 4458 - 4467
Journal Article
PloS one, ISSN 1932-6203, 2014, Volume 9, Issue 11, p. e111898
...) 1-42 oligomers is proposed to underlie cognitive decline in Alzheimer's disease (AD). Alterations in membrane trafficking induced by Abeta oligomers mediates... 
NATURAL OLIGOMERS | HUMAN BRAIN | FORMAZAN EXOCYTOSIS | MULTIDISCIPLINARY SCIENCES | MOUSE MODEL | BEHAVIORAL DEFICITS | A-BETA | SPINE NUMBER | INDUCED SYNAPTIC DEPRESSION | HIPPOCAMPAL-NEURONS | CELLULAR PRION PROTEIN | Synapses - drug effects | Enzyme-Linked Immunosorbent Assay | Humans | Alzheimer Disease - drug therapy | Rats | Mice, Transgenic | Cognition - drug effects | Cognition Disorders - drug therapy | Rats, Sprague-Dawley | Chemistry, Pharmaceutical | Protein Transport | Brain - drug effects | Peptide Fragments - chemistry | Animals | Synapses - metabolism | Alzheimer Disease - metabolism | Drug Design | Protein Binding | Neuroglia - metabolism | Mice | Neurons - metabolism | Amyloid beta-Peptides - chemistry | Oligomers | Brain | Neurons | Analysis | Genetic engineering | Chemical properties | Alzheimer's disease | Neurosciences | Animal models | Peptides | Spine | Memory | Central nervous system | Cognitive ability | Recovery of function | Biology | Neurosurgery | Drug development | Medical schools | Learning | Signal transduction | Receptors | Aging | Age | Binding | Neurodegenerative diseases | Transgenic mice | Phenotypic plasticity | Pharmacology | Lead compounds | Embryos | Chemical compounds | Yang, Cindy | Pathology | Brain research | Plasticity (synaptic) | β-Amyloid | Ligands | Membrane trafficking | Laboratory animals | Alzheimers disease | Human behavior | Binding sites | Synapses | Apoptosis | Animal cognition
Journal Article
PloS one, ISSN 1932-6203, 2014, Volume 9, Issue 11, p. e111899
Amyloid beta (Abeta) 1-42 oligomers accumulate in brains of patients with Mild Cognitive Impairment (MCI... 
ACTIVATION | PROTEIN | LIGANDS | SOLUBLE A-BETA | MULTIDISCIPLINARY SCIENCES | DISEASE | MEMBRANE COMPONENT 1 | SYNAPTIC PLASTICITY | MOLECULAR-BASIS | BRAIN | CELL-DEATH | Protein Structure, Tertiary | Synapses - drug effects | Membrane Proteins - genetics | Humans | Alzheimer Disease - drug therapy | Rats | Receptors, Progesterone - genetics | Cognition - drug effects | Cognition Disorders - drug therapy | Rats, Sprague-Dawley | Receptors, Progesterone - metabolism | Brain - metabolism | Autoradiography | Peptide Fragments - chemistry | Animals | Synapses - metabolism | Alzheimer Disease - metabolism | Protein Binding | Cell Membrane - metabolism | Membrane Proteins - metabolism | Mice | Neurons - metabolism | Amyloid beta-Peptides - chemistry | RNA, Small Interfering - metabolism | Proteins | Oligomers | Hormones, Sex | Chemical properties | Health aspects | Alzheimer's disease | Potentiation | Brain | Neurosciences | Animal models | Toxicity | Spine | Memory | Cognitive ability | Antibodies | Receptors | Rodents | Biocompatibility | Amnesia | Binding | Neurodegenerative diseases | Neurons | Long-term potentiation | Pathological effects | siRNA | Patients | Embryos | Yang, Cindy | Displacement | Membrane proteins | Neurology | Plasticity (synaptic) | Membrane trafficking | Progesterone | Laboratory animals | Alzheimers disease | Synapses | Cancer | Apoptosis | Animal cognition
Journal Article
Alzheimer's research & therapy, ISSN 1758-9193, 2013, Volume 5, Issue 6, pp. 60 - 60
The oligomer cascade hypothesis, which states that oligomers are the initiating pathologic agents in Alzheimer's disease, has all but supplanted the amyloid cascade hypothesis, which suggested... 
WILD-TYPE | ALPHA-HELIX | HUMAN BRAIN | MECHANISM | A-BETA | PLAQUE-FORMATION | PRECURSOR PROTEIN | ION CHANNELS | SYNAPTIC PLASTICITY | NEUROSCIENCES | PEPTIDE | CLINICAL NEUROLOGY
Journal Article