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Blood, ISSN 0006-4971, 12/2011, Volume 118, Issue 23, pp. 6087 - 6096
Journal Article
Journal Article
Blood, ISSN 0006-4971, 04/2010, Volume 115, Issue 16, pp. 3196 - 3205
Journal Article
Blood, ISSN 0006-4971, 09/2012, Volume 120, Issue 11, pp. 2157 - 2158
Journal Article
Nature, ISSN 0028-0836, 2014, Volume 508, Issue 7498, pp. 49 - 54
Many aspects of cellular physiology remain unstudied in somatic stem cells, for example, there are almost no data on protein synthesis in any somatic stem... 
PROGENITOR CELLS | MULTIDISCIPLINARY SCIENCES | MTOR PATHWAY | BONE-MARROW | IN-VIVO | DIAMOND-BLACKFAN ANEMIA | PTEN | S19 DEFICIENCY | SELF-RENEWAL | TRANSLATIONAL CONTROL | PROTEASOME ACTIVITY | Cell Proliferation | Leukemia - pathology | Hematopoietic Stem Cells - pathology | Ribosomes - metabolism | Male | Leukemia - metabolism | Genetic Complementation Test | Ribosomal Proteins - metabolism | Flow Cytometry | Proteasome Endopeptidase Complex - drug effects | Time Factors | Cell Transformation, Neoplastic - genetics | Female | Protein Biosynthesis - genetics | Homeostasis - drug effects | Leukemia - genetics | Hematopoietic Stem Cells - drug effects | PTEN Phosphohydrolase - genetics | PTEN Phosphohydrolase - deficiency | Ribosomal Proteins - genetics | Puromycin - metabolism | Hematopoietic Stem Cells - metabolism | Mutation - genetics | Cell Transformation, Neoplastic - metabolism | Animals | Puromycin - analogs & derivatives | Ribosomes - genetics | Hematopoietic Stem Cells - cytology | Protein Biosynthesis - drug effects | Mice | Kinetics | Proteasome Endopeptidase Complex - metabolism | Cell Transformation, Neoplastic - pathology | Homeostasis - genetics | Physiological aspects | Stem cell research | Protein biosynthesis | B cells | Research | Hematopoietic stem cells | Bone marrow | Mutation | Transplants & implants | Protein synthesis | Stem cells
Journal Article
BBA - Molecular Basis of Disease, ISSN 0925-4439, 06/2014, Volume 1842, Issue 6, pp. 817 - 830
Errors in ribosome biogenesis can result in quantitative or qualitative defects in protein synthesis and consequently lead to improper execution of the genetic... 
RPL5 | 5S rRNA | Ribosome biogenesis stress | Ribosomopathies | RPL11 | p53 | P53 | PROTEIN S19 DEFICIENCY | MESSENGER-RNA TRANSLATION | POLYMERASE I TRANSCRIPTION | GENE DELETIONS | BIOCHEMISTRY & MOLECULAR BIOLOGY | DNA-DAMAGE | C-MYC | CELL-CYCLE ARREST | NUCLEOLAR DISRUPTION | BIOPHYSICS | DIAMOND-BLACKFAN ANEMIA | P53-DEPENDENT CHECKPOINT | Protein biosynthesis | Tumor proteins | Analysis | Tumors
Journal Article
Journal Article
Journal Article
BBA - Molecular Basis of Disease, ISSN 0925-4439, 06/2014, Volume 1842, Issue 6, pp. 765 - 768
Diamond Blackfan anemia is a red cell hypoplasia that typically presents within the first year of life. Most cases of Diamond Blackfan anemia are caused by... 
Ribosomopathy | Nucleolar stress | Anemia | Haploinsufficiency | PROTEIN S19 DEFICIENCY | RNA | BIOCHEMISTRY & MOLECULAR BIOLOGY | 40S RIBOSOMAL-SUBUNITS | TREACHER-COLLINS-SYNDROME | MYELODYSPLASTIC SYNDROME | P53 | BIOPHYSICS | GENE | BIOGENESIS | MOLECULAR-BASIS | MARROW FAILURE | Physiological aspects | Tumor proteins
Journal Article