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Molecular Cell, ISSN 1097-2765, 11/2011, Volume 44, Issue 4, pp. 647 - 659
To prevent ATR activation, telomeres deploy the single-stranded DNA binding activity of TPP1/POT1a. POT1a blocks the binding of RPA to telomeres, suggesting... 
LENGTH REGULATOR | COMPLEX | ABERRANT HOMOLOGOUS RECOMBINATION | MAMMALIAN TELOMERES | REPLICATION PROTEIN-A | HUMAN-CELLS | BIOCHEMISTRY & MOLECULAR BIOLOGY | DYSKERATOSIS-CONGENITA | SINGLE-STRANDED-DNA | CHECKPOINT ACTIVATION | HUMAN POT1 | CELL BIOLOGY | Serine Proteases - genetics | Protein Binding - genetics | Humans | DNA, Single-Stranded - genetics | DNA-Binding Proteins - metabolism | Telomere-Binding Proteins - genetics | Dipeptidyl-Peptidases and Tripeptidyl-Peptidases - metabolism | Cell Cycle Proteins - genetics | Telomere - metabolism | Telomere-Binding Proteins - metabolism | Aminopeptidases - metabolism | Dipeptidyl-Peptidases and Tripeptidyl-Peptidases - genetics | Protein-Serine-Threonine Kinases - metabolism | Recombinant Proteins - metabolism | Serine Proteases - metabolism | Aminopeptidases - genetics | Gene Expression | DNA, Single-Stranded - metabolism | Cell Cycle Proteins - metabolism | Protein-Serine-Threonine Kinases - genetics | Recombinant Proteins - genetics | Signal Transduction - genetics | Ataxia Telangiectasia Mutated Proteins | DNA-Binding Proteins - genetics | DNA, Single-Stranded - chemistry | Mice, Knockout | Animals | DNA Repair | Telomeric Repeat Binding Protein 2 - metabolism | Mice | DNA Damage | HeLa Cells | Telomeric Repeat Binding Protein 2 - genetics | Analysis | DNA | Automated teller machines
Journal Article
Journal Article
MOLECULAR AND CELLULAR BIOLOGY, ISSN 0270-7306, 11/2019, Volume 39, Issue 21
TIN2 is an important regulator of telomere length, and mutations in TINF2, the gene encoding TIN2, cause short-telomere syndromes. While the genetics... 
shelterin | LOCALIZATION | COMPLEX | alternative splicing | PROTECTION | PROTEIN TPP1 | BIOCHEMISTRY & MOLECULAR BIOLOGY | telomere | processivity | TRF1 | CELL BIOLOGY | LENGTH REGULATOR | telomerase | DYSKERATOSIS-CONGENITA | POT1 | TPP1 | MUTATIONS | TIN2
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Journal Article
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