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Biochimica et Biophysica Acta - Proteins and Proteomics, ISSN 1570-9639, 06/2004, Volume 1699, Issue 1-2, pp. 35 - 44
During the maturation of extracellular proteins, disulfide bonds that chemically cross-link specific cysteines are often added to stabilize a protein or to... 
Protein disulfide isomerase | Extracellular protein | Folding catalyst
Journal Article
HAEMATOLOGICA, ISSN 0390-6078, 03/2019, Volume 104, Issue 3, pp. 419 - 421
Journal Article
Circulation, ISSN 0009-7322, 03/2019, Volume 139, Issue 10, pp. 1300 - 1319
BACKGROUND:Platelet-neutrophil interactions contribute to vascular occlusion and tissue damage in thromboinflammatory disease. Platelet glycoprotein Ibα... 
blood platelets | inflammation | neutrophils | protein disulfide isomerase | glycoprotein Ibalpha
Journal Article
Chemico-Biological Interactions, ISSN 0009-2797, 06/2017, Volume 272, pp. 117 - 124
Oxidative stress arising from inflammatory processes is a serious cause of cell and tissue damage. Tempol is an efficient antioxidant with superoxide... 
Protein disulfide isomerase | Reductase activity | Chaperone | Tempol
Journal Article
2011, Protein reviews, ISBN 9781441972729, Volume 14
Web Resource
2011, Protein reviews, ISBN 9781441972729, Volume 14
Web Resource
Methods (San Diego, Calif.), ISSN 1046-2023, 07/2019
This study describes the theoretical basis and the methods for the facile synthesis and characterization of four fluorogenic probes,... 
Journal Article
BLOOD, ISSN 0006-4971, 05/2013, Volume 121, Issue 19, pp. 3779 - 3780
Journal Article
FEBS Journal, ISSN 1742-464X, 04/2008, Volume 275, Issue 8, pp. 1813 - 1823
Adhesive properties of endothelial cells are influenced by the thioldisulfide balance. However, the molecular mechanism of this effect is unclear, although... 
endothelial cells | integrins | protein disulfide isomerase | Protein disulfide isomerase | Endothelial cells | Integrins
Journal Article
11/2012
Protein disulfide isomerases (PDIs) catalyze the oxidation and isomerization of disulfide bonds in proteins passing through the endoplasmic reticulum (ER).... 
disulfide bonds | chaperone | 0487 | Protein Disulfide Isomerase | protein folding | biogenesis & biodegradation | Endoplasmic reticulum
Dissertation
NEW ENGLAND JOURNAL OF MEDICINE, ISSN 0028-4793, 08/2008, Volume 359, Issue 9, pp. 938 - 949
  Thrombosis is a critical event in the arterial diseases associated with myocardial infarction and stroke, and venous thromboembolic disorders account for... 
COAGULATION-FACTOR-XII | MEDICINE, GENERAL & INTERNAL | TISSUE FACTOR ACTIVITY | PROTEIN-DISULFIDE-ISOMERASE | FACTOR PROCOAGULANT ACTIVITY | BLOOD-COAGULATION | PLATELET-AGGREGATION | FACTOR-POSITIVE MICROPARTICLES | IN-VIVO | P-SELECTIN | VON-WILLEBRAND-FACTOR | Heart attacks | Blood platelets | Nitric oxide | Collagen | Blood clots | Endothelium
Journal Article
by Eunyoug Lee and and Do Hee Lee
BMB Reports, ISSN 1976-6696, 2017, Volume 50, Issue 8, p. 401
The protein disulfide isomerase (PDI) family is a group of multifunctional endoplasmic reticulum (ER) enzymes that mediate the formation of disulfide bonds,... 
Protein disulfide isomerase | Chaperone | Cancer | Proteo-stasis
Journal Article
BLOOD, ISSN 0006-4971, 04/2017, Volume 129, Issue 16, pp. 2291 - 2302
Expanding evidence indicates multiple interactions between the hemostatic system and innate immunity, and the coagulation and complement cascades. Here we show... 
CROSS-TALK | THIOL ISOMERASES | WHOLE-BLOOD | PROTEIN DISULFIDE-ISOMERASE | ENDOTHELIAL-CELLS | IN-VIVO | DEEP-VEIN THROMBOSIS | PAROXYSMAL-NOCTURNAL HEMOGLOBINURIA | HEMATOLOGY | VON-WILLEBRAND-FACTOR | TISSUE FACTOR
Journal Article
HAEMATOLOGICA, ISSN 0390-6078, 03/2019, Volume 104, Issue 3, pp. 546 - 555
Combination chemotherapy has proven to be a favorable strategy to treat acute leukemia. However, the introduction of novel compounds remains challenging and is... 
NETWORK | INDUCED APOPTOSIS | PROTEIN DISULFIDE-ISOMERASE | RESISTANCE | REDOX | MECHANISMS | INHIBITOR | HEMATOLOGY | REVEALS
Journal Article
ChemMedChem, ISSN 1860-7179, 1/2018, Volume 13, Issue 2, pp. 164 - 177
Protein disulfide isomerase (PDI) is overexpressed in glioblastoma, the most aggressive form of brain cancer, and folds nascent proteins responsible for the... 
unfolded protein response | drug discovery | protein disulfide isomerase | oxidoreductases | cancer
Journal Article
BLOOD, ISSN 0006-4971, 11/2013, Volume 122, Issue 22, pp. 3642 - 3650
The platelet protein disulfide isomerase called ERp57 mediates platelet aggregation, but its role in thrombus formation is unknown. To determine the specific... 
ADHESION | ACTIVATION | ALPHA-IIB-BETA-3 | PROTEIN DISULFIDE-ISOMERASE | IN-VIVO | MEGAKARYOCYTE | MICE | HEMATOLOGY | HEMOSTASIS | ANTIPLATELET THERAPY | AGGREGATION
Journal Article
The EMBO Journal, ISSN 0261-4189, 08/2019, Volume 38, Issue 15, pp. e102743 - n/a
ATF 6 is a major signal transducer for cellular reprogramming in response to protein mis‐folding in the endoplasmic reticulum. However, the mechanism by which... 
BIOCHEMISTRY & MOLECULAR BIOLOGY | CELL BIOLOGY | Proteins | Protein disulfide-isomerase | Protein folding | Endoplasmic reticulum | Golgi apparatus | Index Medicus
Journal Article
Microbiology and Biotechnology Letters, ISSN 1598-642X, 09/2018, Volume 46, Issue 3, pp. 244 - 252
Journal Article
American Journal of Physiology - Renal Physiology, ISSN 0363-6127, 08/2017, Volume 313, Issue 2, pp. F461 - F466
The role and mechanism of renal protein disulfide isomerase (PDI) in blood pressure regulation has not been tested before. Here, we test this possibility in... 
Protein disulfide isomerase | Keap1 | Oxidative stress | receptor | Nrf2 | Index Medicus | protein disulfide isomerase | oxidative stress | AT1 receptor
Journal Article
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