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Journal of the National Cancer Institute, ISSN 0027-8874, 06/2005, Volume 97, Issue 12, pp. 880 - 887
Background. The epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor erlotinib (also known as Tarceva or OSI-774) has shown promising response... 
CELL LUNG-CANCER | BREAST-CANCER | AMPLIFICATION | ONCOLOGY | CYCLIN D1 | TYROSINE KINASE | PHOSPHATIDYLINOSITOL 3-KINASE | AKT | INHIBITORS | EXPRESSION | BRAIN-TUMORS | Erlotinib Hydrochloride | Immunohistochemistry | Receptor, Epidermal Growth Factor - genetics | Phosphorylation | Area Under Curve | Humans | Middle Aged | Receptor, Epidermal Growth Factor - drug effects | Drug Resistance, Neoplasm | Male | Antineoplastic Agents - therapeutic use | Antineoplastic Agents - administration & dosage | Glioma - metabolism | Supratentorial Neoplasms - drug therapy | PTEN Phosphohydrolase | Glioma - pathology | Tumor Suppressor Proteins - genetics | Dacarbazine - analogs & derivatives | Protein-Serine-Threonine Kinases - antagonists & inhibitors | Phosphoric Monoester Hydrolases - drug effects | Adult | Female | Quinazolines - administration & dosage | Protein-Serine-Threonine Kinases - metabolism | Proto-Oncogene Proteins - metabolism | Proto-Oncogene Proteins - antagonists & inhibitors | Dacarbazine - administration & dosage | Phosphoric Monoester Hydrolases - genetics | Drug Administration Schedule | Supratentorial Neoplasms - pathology | Supratentorial Neoplasms - metabolism | In Situ Hybridization, Fluorescence | Proto-Oncogene Proteins c-akt | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Quinazolines - therapeutic use | Aged | Tumor Suppressor Proteins - drug effects | Mutation | Glioma - drug therapy | Care and treatment | Diagnosis | Research | Gliomas | Protein kinases | Risk factors | Proteins | Oncology | Gene expression | Tumors | Index Medicus
Journal Article
Journal Article
Journal Article
JOURNAL OF MEDICINAL CHEMISTRY, ISSN 0022-2623, 03/2010, Volume 53, Issue 5, pp. 2239 - 2249
Journal Article
International Journal of Oncology, ISSN 1019-6439, 1/2013, Volume 42, Issue 1, pp. 118 - 126
Journal Article
Experimental Neurology, ISSN 0014-4886, 2007, Volume 206, Issue 2, pp. 269 - 279
Several lines of evidence indicate that phosphatidylinositol 3-kinase (PI3K) and PI3K-protein kinase B/Akt (PKB/Akt) signal pathway mediate the pain... 
Immunohistochemistry | Spinal cord | Protein kinase B/Akt | Dorsal root ganglia | Phosphatidylinositol 3-kinase | Neuropathic pain | MECHANICAL ALLODYNIA | DEPENDENT PHOSPHORYLATION | THERMAL HYPERALGESIA | protein kinase B/Akt | PRIMARY AFFERENT NEURONS | dorsal root ganglia | NECROSIS-FACTOR-ALPHA | NEUROSCIENCES | NEUROTROPHIC FACTORS | neuropathic pain | spinal cord | immunohistochemistry | PRIMARY SENSORY NEURONS | LONG-TERM POTENTIATION | GROWTH-FACTOR | NF-KAPPA-B | phosphatidylinositol 3-kinase | Male | Ganglia, Spinal - physiopathology | Peripheral Nervous System Diseases - physiopathology | Phosphatidylinositol 3-Kinases - metabolism | Phosphatidylinositol 3-Kinases - antagonists & inhibitors | Neurons, Afferent - enzymology | Ganglia, Spinal - enzymology | Neuralgia - physiopathology | Proto-Oncogene Proteins c-akt - metabolism | Enzyme Inhibitors - pharmacology | Spinal Cord - enzymology | Peripheral Nervous System Diseases - enzymology | Rats | Neuralgia - enzymology | Enzyme Activation - drug effects | Rats, Sprague-Dawley | Neuralgia - drug therapy | Hyperalgesia - physiopathology | Up-Regulation - drug effects | Animals | Hyperalgesia - drug therapy | Signal Transduction - drug effects | Spinal Cord - physiopathology | Ligation - adverse effects | Hyperalgesia - enzymology | Peripheral Nervous System Diseases - drug therapy | Proto-Oncogene Proteins c-akt - antagonists & inhibitors | Physiological aspects | Protein kinases | Index Medicus
Journal Article
Journal Article
The EMBO Journal, ISSN 0261-4189, 12/2006, Volume 25, Issue 24, pp. 5716 - 5725
Journal Article
Neuron, ISSN 0896-6273, 2009, Volume 62, Issue 4, pp. 471 - 478
NMDA receptor subunit composition varies throughout the brain, providing molecular diversity in NMDA receptor function. The NR2 subunits (NR2A–D) in large part... 
CELLBIO | MOLNEURO | SIGNALING | B-GAMMA | INSULIN | NEURONAL SURVIVAL | POTASSIUM DEPOLARIZATION | ENDOPLASMIC-RETICULUM | AKT | FACTOR-I | MEMBRANE-PROTEINS | SYNAPTIC PLASTICITY | NEUROSCIENCES | METHYL-D-ASPARTATE | Insulin-Like Growth Factor I - pharmacology | Gene Expression - drug effects | Gene Expression - genetics | Humans | Cerebellum - drug effects | Receptors, N-Methyl-D-Aspartate - metabolism | Neurons - cytology | Protein Transport - physiology | Green Fluorescent Proteins - genetics | Protein Transport - drug effects | Hippocampus - drug effects | N-Methylaspartate - pharmacology | Receptors, N-Methyl-D-Aspartate - genetics | Transfection - methods | Alanine - genetics | Dendrites - physiology | Neurons - physiology | Phosphorylation - drug effects | Neurons - drug effects | Oncogene Protein v-akt - metabolism | Proto-Oncogene Proteins c-akt - metabolism | Dendrites - drug effects | Immunoprecipitation - methods | Cerebellum - metabolism | Valine - analogs & derivatives | Cells, Cultured | Rats | Serine - genetics | Excitatory Amino Acid Antagonists - pharmacology | Protein Structure, Tertiary - genetics | Mutation - genetics | Serine - metabolism | 14-3-3 Proteins - metabolism | Hippocampus - metabolism | Animals | Signal Transduction - drug effects | Cerebellum - cytology | Signal Transduction - physiology | Biotinylation - methods | Mice | Valine - pharmacology | In Vitro Techniques | Cell Line, Transformed | Luminescent Proteins - metabolism | Brain | Methyl aspartate | Nervous system diseases | Neurons | Protein kinases | Proteins | Phosphorylation | Neurotoxicity | Brain research | Rodents | Software | Insulin-like growth factors | Mutation | Kinases | Binding sites | Index Medicus
Journal Article