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Science, ISSN 0036-8075, 11/2007, Volume 318, Issue 5855, pp. 1455 - 1458
Journal Article
Nature, ISSN 0028-0836, 08/2012, Volume 488, Issue 7413, pp. 670 - 674
The inflammasome regulates the release of caspase activation-dependent cytokines, including interleukin (IL)-1 beta, IL-18 and high-mobility group box 1... 
PATHWAYS | APOPTOSIS | ACID | PROTEIN-KINASE PKR | MULTIDISCIPLINARY SCIENCES | INFECTION | NLRP3 INFLAMMASOME | ELF2-ALPHA | STRESS | BINDING | SUBSTRATE RECOGNITION | Crystallins - metabolism | Interleukin-6 - analysis | Phosphorylation | Inflammasomes - metabolism | NLR Family, Pyrin Domain-Containing 3 Protein | eIF-2 Kinase - metabolism | Humans | Salmonella Infections - immunology | Male | Salmonella Infections - metabolism | HMGB1 Protein - secretion | Interleukin-1beta - blood | eIF-2 Kinase - deficiency | Adenosine Triphosphate - pharmacology | CARD Signaling Adaptor Proteins - metabolism | Transfection | Interleukin-6 - blood | Rotenone - pharmacology | Female | Membrane Proteins - metabolism | Escherichia coli - physiology | Macrophages, Peritoneal - drug effects | eIF-2 Kinase - genetics | Calcium-Binding Proteins - metabolism | Cell Line | Salmonella typhimurium - physiology | Interleukin-18 - blood | Salmonella typhimurium - immunology | Inflammasomes - agonists | Mice, Inbred C57BL | Peritonitis - metabolism | Cells, Cultured | Escherichia coli - immunology | Antigens, Bacterial - pharmacology | Escherichia coli Infections - metabolism | eIF-2 Kinase - antagonists & inhibitors | Apoptosis Regulatory Proteins - metabolism | Animals | Carrier Proteins - metabolism | Bacterial Toxins - pharmacology | Uric Acid - pharmacology | RNA, Double-Stranded - immunology | RNA, Double-Stranded - pharmacology | Escherichia coli Infections - immunology | Mice | Adaptor Proteins, Signal Transducing - metabolism | Macrophages, Peritoneal - metabolism | HMGB1 Protein - blood | Physiological aspects | Chromosomal proteins | Research | Cytokines | Aluminum | Health aspects | Proteins | E coli | Pathogenesis | Plasmids | Bone marrow | Bacteria | Kinases | Index Medicus
Journal Article
by Kang, R and Tang, DL
SCIENCE SIGNALING, ISSN 1937-9145, 10/2012, Volume 5, Issue 247
Double-stranded RNA-dependent protein kinase (PKR) is implicated in inflammation and immune dysfunction through its regulation of mitogen-activated protein... 
APOPTOSIS | IMMUNITY | KAPPA-B KINASE | ACTIVATION | INTERFERON | PROTEIN-KINASE PKR | BIOCHEMISTRY & MOLECULAR BIOLOGY | REGULATES AUTOPHAGY | HMGB1 RELEASE | IL-1-BETA | INFLAMMASOMES | CELL BIOLOGY
Journal Article
European Journal of Immunology, ISSN 0014-2980, 05/2013, Volume 43, Issue 5, pp. 1147 - 1152
Journal Article
Journal Article
细胞研究:英文版, ISSN 1001-0602, 2013, Volume 23, Issue 2, pp. 168 - 170
Inflammasomes are multiprotein complexes that detect and respond to foreign and endogenous danger signals by activating caspase-1; ac-tive caspase-1, in turn,... 
蛋白激酶 | 内源性 | PKR | 复合物 | 生物活性 | 细胞因子 | ACTIVATION | HMGB1 | PROTEIN-KINASE PKR | ELF2-ALPHA | SUBSTRATE RECOGNITION | CELL BIOLOGY | Animals | Carrier Proteins - metabolism | Inflammasomes - metabolism | NLR Family, Pyrin Domain-Containing 3 Protein | Humans | Shock, Septic - prevention & control | Nitric Oxide - metabolism | Index Medicus | Research Highlight
Journal Article
Scientific Reports, ISSN 2045-2322, 12/2017, Volume 7, Issue 1, pp. 3335 - 9
Journal Article
PLoS Pathogens, ISSN 1553-7366, 03/2016, Volume 12, Issue 3, pp. e1005489 - e1005489
Journal Article