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1. Full Text 5′-Triphosphate-Dependent Activation of PKR by RNAs with Short Stem-Loops
by Subba Rao Nallagatla and Jungwook Hwang and Rebecca Toroney and Xiaofeng Zheng and Craig E. Cameron and Philip C. Bevilacqua
Science (American Association for the Advancement of Science), ISSN 0036-8075, 11/2007, Volume 318, Issue 5855, pp. 1455 - 1458
Phosphorylation | Double stranded RNA | Delta cells | RNA | Epithelial cells | Cell lines | Viruses | Innate immunity | Reports | Biochemistry | Vero cells | Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Fundamental and applied biological sciences. Psychology | Fundamental immunology | Biological and medical sciences | Immunobiology | Genetics of the immune response | eIF-2 Kinase - metabolism | Humans | Cercopithecus aethiops | Molecular Sequence Data | RNA - genetics | Transfection | Base Sequence | Eukaryotic Initiation Factor-2 - metabolism | RNA, Double-Stranded - metabolism | DEAD-box RNA Helicases - metabolism | Nucleic Acid Conformation | RNA, Double-Stranded - chemistry | Vero Cells | RNA - metabolism | DEAD Box Protein 58 | Interferon-alpha - metabolism | Immunity, Innate | RNA - chemistry | Polyphosphates - metabolism | Interferon-alpha - immunology | Animals | Interferon-beta - metabolism | RNA, Double-Stranded - genetics | Cell Line, Tumor | Enzyme Activation | Phosphoric Monoester Hydrolases - metabolism | Physiological aspects | Genetic aspects | Properties | Protein kinases | Viroids | Genetics | Immunology | Molecular biology | Kinases | Ribonucleic acid--RNA | Ribonucleic acid | Index Medicus
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2. Full Text PKR: A kinase to remember
by Gal-Ben-Ari, Shunit and Barrera, Iliana and Ehrlich, Marcelo and Rosenblum, Kobi
Frontiers in molecular neuroscience, ISSN 1662-5099, 01/2019, Volume 11, pp. 480 - 480
Learning and memory | Signal transduction | Alzheimer’s disease | Protein synthesis | PKR | Aging | Metabolic stress | Cancer | Neurosciences | Neurosciences & Neurology | Life Sciences & Biomedicine | Science & Technology | Influence | Research | Metabolic syndrome X | Protein kinases | Risk factors | Cell proliferation | eIF-2 kinase | Phosphorylation | Transcription | Therapeutic applications | Gene regulation | Metabolism | Kinases | Proteins | Protein kinase R | Neurodegeneration | Information processing | Cell cycle | Interferon | Endoplasmic reticulum | Metabolic disorders | Apoptosis | protein synthesis | metabolic stress | aging | learning and memory | signal transduction
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3. Full Text PKR activation by noncanonical ligands: a 5 '-triphosphate requirement versus antisense contamination
by Safran, Sarah A and Eckert, Debra M and Leslie, Evan A and Bass, Brenda L
RNA (Cambridge), ISSN 1355-8382, 09/2019, Volume 25, Issue 9, pp. 1192 - 1201
Life Sciences & Biomedicine | Biochemistry & Molecular Biology | Science & Technology | eIF-2 kinase | Phosphorylation | Transcription | Double-stranded RNA | Antisense RNA | Ultracentrifugation | RNA polymerase | Kinases | DNA-directed RNA polymerase | Contamination | Cell activation | Protein kinase | Interferon | Dimerization | Index Medicus | dsRNA | T7 RNA polymerase | ss-dsRNA | PKR | snoRNA | antisense
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4. Full Text Structure and Degradation of Circular RNAs Regulate PKR Activation in Innate Immunity
by Liu, Chu-Xiao and Li, Xiang and Nan, Fang and Jiang, Shan and Gao, Xiang and Guo, Si-Kun and Xue, Wei and Cui, Yange and Dong, Kaige and Ding, Huihua and Qu, Bo and Zhou, Zhaocai and Shen, Nan and Yang, Li and Chen, Ling-Ling
Cell (Cambridge), ISSN 0092-8674, 05/2019, Volume 177, Issue 4, pp. 865 - 880.e21
circRNAs | systemic lupus erythematosus | double-stranded RNAs | circular RNAs | circRNA structure | RNase L | PKR | circRNA degradation | autoimmune disease | innate immune responses | Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Cell Line | Leukocytes, Mononuclear - metabolism | Phosphorylation | Endoribonucleases - metabolism | eIF-2 Kinase - metabolism | Humans | Middle Aged | RNA, Circular - metabolism | Immunity, Innate - genetics | eIF-2 Kinase - immunology | Virus Diseases - metabolism | Autoimmune Diseases - genetics | RNA, Circular - genetics | Leukocytes, Mononuclear - immunology | Lupus Erythematosus, Systemic - genetics | RNA Splicing - genetics | Adolescent | Adult | Female | RNA, Double-Stranded - metabolism | RNA, Circular - physiology | RNA - metabolism | RNA Stability - physiology | Virus diseases | Lupus | Medical colleges | Systemic lupus erythematosus | RNA | Ribonuclease | Molecular biology | T cells | Cells | Protein kinases | Index Medicus
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5. Full Text STAU1 binding 3′ UTR IRAlus complements nuclear retention to protect cells from PKR-mediated translational shutdown
by Elbarbary, Reyad A and Li, Wencheng and Tian, Bin and Maquat, Lynne E
Genes & development, ISSN 0890-9369, 07/2013, Volume 27, Issue 13, pp. 1495 - 1510
Inverted repeat Alu elements | Translation | STAU1 | PKR | Myogenesis | p54 | Nuclear export | Genetics & Heredity | Life Sciences & Biomedicine | Developmental Biology | Science & Technology | Cell Biology | RNA-Binding Proteins - genetics | RNA Transport | Cytoskeletal Proteins - genetics | Humans | Cells, Cultured | Gene Expression Regulation | RNA, Messenger - metabolism | Cell Nucleus - metabolism | HEK293 Cells | Protein Binding | Cytoskeletal Proteins - metabolism | 3' Untranslated Regions | Alu Elements - genetics | RNA-Binding Proteins - metabolism | Nervous system | Degeneration | Protein kinases | Analysis | Index Medicus | nuclear export | translation | Research Paper | myogenesis | p54nrb | inverted repeat Alu elements
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6. Full Text Impact of Protein Kinase PKR in Cell Biology: from Antiviral to Antiproliferative Action
by M. A. García and J. Gil and I. Ventoso and S. Guerra and E. Domingo and C. Rivas and M. Esteban
Microbiology and Molecular Biology Reviews, ISSN 1092-2172, 12/2006, Volume 70, Issue 4, pp. 1032 - 1060
Life Sciences & Biomedicine | Microbiology | Science & Technology | Fundamental and applied biological sciences. Psychology | Biological and medical sciences | Cells - drug effects | Antiviral Agents - pharmacology | Animals | eIF-2 Kinase - physiology | Signal Transduction - drug effects | Interferons - pharmacology | Humans | Cell Biology | Interferon | Research | Bacterial genetics | Protein kinases | Cellular control mechanisms | Side effects | RNA-protein interactions | Cellular biology | Kinases | Antiviral drugs | Apoptosis | Index Medicus | Reviews
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