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Biochemical journal, ISSN 0264-6021, 07/2009, Volume 421, Issue 1, pp. 29 - 42
mTOR (mammalian target of rapamycin) stimulates cell growth by phosphorylating and promoting activation of AGC (protein kinase A/protein kinase G/protein... 
Phosphoinositide 3-kinase (PI3K) | Akt/protein kinase B (PKB) | Serum and glucocorticoid protein kinase (SGK) | P70 ribosomal S6 kinase (S6K) | Kinase inhibitor | Cancer | IN-VIVO ROLE | PROTEIN-KINASE B/AKT | BINDING PARTNER | RAG GTPASES | PHOSPHORYLATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | AKT | IDENTIFICATION | P70 S6 KINASE | kinase inhibitor | phosphoinositide 3-kinase (PI3K) | p70 ribosomal S6 kinase (S6K) | HYDROPHOBIC MOTIF | cancer | serum and glucocorticoid protein kinase (SGK) | PDK1 | Cell Line | Humans | Multiprotein Complexes | Morpholines - pharmacology | Transcription Factors - antagonists & inhibitors | Gene Expression Profiling | G1 Phase - drug effects | Pyrimidines - pharmacology | Morpholines - chemistry | Pyrimidines - chemistry | Mechanistic Target of Rapamycin Complex 1 | Gene Expression Regulation - drug effects | Proteins | Transcription Factors - metabolism | Animals | Fibroblasts - drug effects | Cell Proliferation - drug effects | Mice | TOR Serine-Threonine Kinases | Fibroblasts - metabolism | PI3K, phosphoinositide 3-kinase | PDK, 3-phosphoinositide-dependent protein kinase | AMPK, AMP-activated protein kinase | mTORC, mTOR complex | DTT, dithiothreitol | SPHK, sphingosine kinase | ERK, extracellular-signal-regulated kinase | RSK, ribosomal S6 kinase | PH domain, pleckstrin homology domain | protein kinase B (PKB) | protein kinase G | NDRG1, N-Myc downstream-regulated gene-1 | IGF, insulin-like growth factor | mTOR, mammalian target of rapamycin | GST, glutathione transferase | SGK, serum and glucocorticoid protein kinase | PKC, protein kinase C | S6K, p70 ribosomal S6 kinase | eIF4E, eukaryotic initiation factor 4E | 4E-BP1, eIF4E-binding protein 1 | protein kinase C family | Akt | PRAS40, proline-rich Akt substrate of 40 kDa | HEK-293 cell, human embryonic kidney 293 cell | MEF, mouse embryonic fibroblast | AGC family, protein kinase A | MAPK, mitogen-activated protein kinase
Journal Article
International journal of oncology, ISSN 1019-6439, 01/2013, Volume 42, Issue 1, pp. 118 - 126
Journal Article
British journal of clinical pharmacology, ISSN 0306-5251, 2016, Volume 82, Issue 4, pp. 943 - 956
Journal Article
Biochemical journal, ISSN 1470-8728, 2007, Volume 404, Issue 3, pp. 449 - 458
Recent genetic knock-in and pharmacological approaches have suggested that, of class IA PI3Ks (phosphatidylinositol 3-kinases), it is the p110α isoform... 
Phosphatidylinositol 3-kinase (PI3K) | Protein kinase B/akt | Insulin signalling | PIK3CB | PIK3CA | AS252424 | 3T3-L1 ADIPOCYTES | 3-kinase (PI3K) | CATALYTIC SUBUNIT | P110-ALPHA | protein kinase B/Akt | BIOCHEMISTRY & MOLECULAR BIOLOGY | insulin signalling | PHOSPHOINOSITIDE 3-KINASE | P110-BETA | phosphatidylinositol | PIK3CA GENE | HIGH-FREQUENCY | EMBRYONIC LETHALITY | BREAST CANCERS | GROWTH-FACTOR | Recombinant Proteins - metabolism | Cell Line | Cricetinae | Enzyme Inhibitors - metabolism | Isoenzymes - genetics | Humans | Phosphatidylinositol 3-Kinases - metabolism | Recombinant Proteins - genetics | Phosphatidylinositol 3-Kinases - antagonists & inhibitors | Phosphatidylinositol 3-Kinases - genetics | Insulin - metabolism | Animals | Isoenzymes - metabolism | Enzyme Inhibitors - chemistry | Signal Transduction - physiology | Mice | Molecular Structure | Proto-Oncogene Proteins c-akt - metabolism | Isoenzymes - antagonists & inhibitors | Proto-Oncogene Proteins c-akt - antagonists & inhibitors | FBS, fetal bovine serum | Akt | PKB, protein kinase B | GPCR, G-protein-coupled receptor | DMEM, Dulbecco's modified Eagle's medium | NCS, newborn calf serum | SH2, Src homology 2 | CHO-IR cells, Chinese-hamster ovary cells expressing human insulin receptor | PI3K, phosphatidylinositol 3-kinase | PI, phosphatidylinositol | phosphatidylinositol 3-kinase (PI3K) | protein kinase B
Journal Article
Proceedings of the National Academy of Sciences - PNAS, ISSN 0027-8424, 11/2016, Volume 113, Issue 44, pp. 12538 - 12543
Increased levels of a cleaved form of prolactin (molecular weight 16 kDa) have been associated with preeclampsia. To study the effects of prolactin on blood... 
Hypertension | Lactation | Protein kinase B/Akt | ACTIVATION | protein kinase B/Akt | CANCER CELLS | RAT | MULTIDISCIPLINARY SCIENCES | PREECLAMPSIA | PREGNANCY | 16K PROLACTIN | lactation | MICE | hypertension | EXPRESSION | CARBOXYPEPTIDASE-D | Blood pressure | Prolactin | Health aspects | Nitric oxide | Biological Sciences | Akt | protein kinase B
Journal Article
Journal Article