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The Journal of surgical research, ISSN 0022-4804, 3/2017, Volume 209, pp. 191 - 198
Journal Article
Scientific Reports, ISSN 2045-2322, 12/2019, Volume 9, Issue 1, pp. 1324 - 1324
Protein kinase D2 (PKD2) has been reported to be related with progression and invasion in various cancers. However, its prognostic value and the underlying... 
APOPTOSIS | INVASION | METASTASIS | PROTEIN-KINASE-D | MULTIDISCIPLINARY SCIENCES | CANCER STATISTICS | NF-KAPPA-B | EXPRESSION | MEMBER | FAMILY
Journal Article
BRITISH JOURNAL OF PHARMACOLOGY, ISSN 0007-1188, 08/2014, Volume 171, Issue 16, pp. 3895 - 3907
Background and PurposePulmonary arteries (PAs) are innervated, but little is known about the role of neuronal axis in pulmonary hypertension (PH). Here, we... 
ACTIVATION | ARTERIES | RAT | PROTEIN-KINASE-D | CA2 | PHOSPHORYLATION | PHARMACOLOGY & PHARMACY | SMOOTH-MUSCLE-CELLS | ANGIOTENSIN-II | MECHANISMS | NEUROPEPTIDE-Y
Journal Article
JOURNAL OF CELL BIOLOGY, ISSN 0021-9525, 06/2012, Volume 197, Issue 7, pp. 983 - 996
Epidermal growth factor receptor (EGFR) signaling is one of the crucial factors in breast cancer malignancy. Breast cancer cells often overexpress Arf6 and its... 
FIBRONECTIN RECEPTOR | 3D MICROENVIRONMENTS | PROTEIN-KINASE-D | CELL-MIGRATION | TRANS-GOLGI NETWORK | EXTRACELLULAR-MATRIX DEGRADATION | INTEGRIN BETA-1 | PLASMA-MEMBRANE | ALPHA-5-BETA-1 INTEGRIN | ARF6 | CELL BIOLOGY
Journal Article
Cell, ISSN 0092-8674, 01/2009, Volume 136, Issue 2, pp. 235 - 248
Dysfunction and loss of insulin-producing pancreatic β cells represent hallmarks of diabetes mellitus. Here, we show that mice lacking the mitogen-activated... 
CELLBIO | HUMDISEASE | SIGNALING | PLASMA-MEMBRANE TRANSPORT | SKELETAL-MUSCLE | TUMOR-NECROSIS-FACTOR | ACTIVATION | PROTEIN-KINASE-D | GOLGI NETWORK | BIOCHEMISTRY & MOLECULAR BIOLOGY | NEUROTENSIN SECRETION | P38 MAPK | PANCREATIC BETA-CELLS | P38-ALPHA | CELL BIOLOGY
Journal Article
DEVELOPMENTAL CELL, ISSN 1534-5807, 09/2012, Volume 23, Issue 3, pp. 560 - 572
Integrin recycling is critical for cell migration. Protein kinase D (PKD) mediates signals from the platelet-derived growth factor receptor (PDGF-R) to control... 
CANCER-CELLS | EFFECTOR | TRANSPORT | 3D MICROENVIRONMENTS | PROTEIN-KINASE-D | D-MEDIATED PHOSPHORYLATION | TRAFFICKING | DEVELOPMENTAL BIOLOGY | BINDING | ALPHA-5-BETA-1 INTEGRIN | CELL BIOLOGY
Journal Article
MOLECULAR BIOLOGY OF THE CELL, ISSN 1059-1524, 04/2012, Volume 23, Issue 8, pp. 1475 - 1485
During wound healing, hemidesmome disassembly enables keratinocyte migration and proliferation. Hemidesmosome dynamics are altered downstream of epidermal... 
CYTOPLASMIC DOMAIN | D PKD | F-ACTIN | PLECTIN | ALPHA-6-BETA-4 INTEGRIN | PROTEIN-KINASE-D | EPIDERMAL-GROWTH | EPIDERMOLYSIS-BULLOSA | BINDING | SUBUNIT | CELL BIOLOGY
Journal Article
AUTOPHAGY, ISSN 1554-8627, 03/2012, Volume 8, Issue 3, pp. 433 - 434
Journal Article
EMBO molecular medicine, ISSN 1757-4676, 07/2018, Volume 10, Issue 7, p. e8536
The myocyte enhancer factor 2 (MEF2) regulates transcription in cardiac myocytes and adverse remodeling of adult hearts. Activators of G protein-coupled... 
Immunology | prostaglandin E2 | myocyte enhancer factor 2 | protein kinase D | histone deacetylase 5 | p21‐activated kinase 2 | Cardiovascular System
Journal Article
Annals of Surgical Oncology, ISSN 1068-9265, 6/2019, Volume 26, Issue 6, pp. 1934 - 1941
The impact of specific co-mutations in epidermal growth factor receptor (EGFR)-mutated lung adenocarcinoma is unclear.Tissues from 147 consecutive patients... 
Oncology | Medicine & Public Health | Surgical Oncology | Surgery | SURGERY | TRIALS | ONCOLOGY | PROTEIN-KINASE-D | RESISTANCE | KRAS | CANCER | Index Medicus
Journal Article
Journal of virology, ISSN 0022-538X, 12/2018, Volume 92, Issue 23
The assembly of new herpes simplex virus 1 (HSV-1) particles takes place in the nucleus. These particles then travel across the two nuclear membranes and... 
GGA1 | Arf | arfaptin | PKD | protein kinase D | HSV | CERT | transport | Nir2 | egress | COMPLEX | NUCLEAR-MEMBRANE | VIROLOGY | GENE | U(S)3 PROTEINS | TRANS-GOLGI NETWORK | VESICLE FORMATION | SURFACE | VESICULAR TRANSPORT | ENDOPLASMIC-RETICULUM | TYPE-1 U(L)34
Journal Article
PLoS ONE, ISSN 1932-6203, 2011, Volume 6, Issue 7, pp. e22453 - e22453
Background: Despite over forty years of investigation on low-level light therapy (LLLT), the fundamental mechanisms underlying photobiomodulation at a cellular... 
CYTOCHROME-C-OXIDASE | CELLS | KAPPA-B ACTIVATION | PROTEIN-KINASE-D | SIGNALING PATHWAY | RED-LIGHT | MULTIDISCIPLINARY SCIENCES | INFRARED RADIATION | GENE-EXPRESSION | TRANSCRIPTION FACTOR | IR RADIATION | Embryo, Mammalian - radiation effects | Luciferases - metabolism | Reactive Oxygen Species - metabolism | Signal Transduction | Cells, Cultured | Immunoblotting | NF-kappa B - metabolism | Antioxidants - pharmacology | Mitochondria - drug effects | Embryo, Mammalian - metabolism | Pregnancy | Animals | Fibroblasts - radiation effects | NF-kappa B - genetics | Embryo, Mammalian - cytology | Adenosine Triphosphate - metabolism | Mitochondria - radiation effects | Female | Fibroblasts - cytology | Mice | Low-Level Light Therapy | Fibroblasts - metabolism | Antioxidants | Lasers in surgery | Genes | Luciferase | Radiation | Genetic engineering | Mitogens | Phototherapy | Lasers in medicine | Cytochrome | Bioluminescence | Reactive oxygen species | Transcription factors | Laboratories | Biology | Activation | Mitochondria | Cell growth | E coli | Lasers | Laser radiation | Antimycin A | Fibroblasts | Infrared radiation | NF-κB protein | Oxygen | Engineering schools | Level (quantity) | Dermatology | Transgenic mice | Inflammation | Embryo fibroblasts | Dentistry | Light therapy | Gene expression | Embryos | Rotenone | Medicine | Signaling | Inhibitors | Paraquat | Electron transport | Respiration | Apoptosis | Index Medicus
Journal Article
Molecular and Cellular Pharmacology, 2017, Volume 9, Issue 1, pp. 1 - 4
Journal Article
Biochemical Journal, ISSN 0264-6021, 12/2007, Volume 408, Issue 3, pp. 297 - 315
The specificities of 65 compounds reported to be relatively specific inhibitors of protein kinases have been profiled against a panel of 70-80 protein kinases.... 
Drug discovery | Kinase profiling | Protein kinase | Anti-cancer drugs | Inhibitor specificity | RHO-ASSOCIATED KINASE | TUMOR PROGRESSION | FAMILY-MEMBERS | BIOCHEMISTRY & MOLECULAR BIOLOGY | CELL-PROLIFERATION | protein kinase | P38 MAP KINASE | CYCLIN-DEPENDENT KINASES | RECEPTOR TYROSINE KINASES | drug discovery | kinase profiling | SB 203580 | anti-cancer drugs | ISOFORMS IN-VITRO | P90 RSK | inhibitor specificity | Amino Acid Sequence | Cell Line | Phosphorylation | Recombinant Proteins - antagonists & inhibitors | Animals | Mitogen-Activated Protein Kinases - antagonists & inhibitors | Humans | Drug Design | Protein Kinase Inhibitors - pharmacology | Enzyme Activation | Mitogen-Activated Protein Kinases - metabolism | Spodoptera | Index Medicus | Yes1, Yamaguchi sarcoma viral oncogene homologue 1 | CSK, C-terminal Src kinase | Lck, lymphocyte cell-specific protein-tyrosine kinase | EGF, epidermal growth factor | FGF-R, fibroblast-growth-factor receptor | PAK, p21-activated protein kinase | PDK, 3-phosphoinositide-dependent protein kinase | PI3K, phosphatidylinositol (phosphoinositide) 3-kinase | NEK, NIMA (never in mitosis in Aspergillus nidulans)-related kinase | RSK, p90 ribosomal S6 kinase | HEK-293 cells, human embryonic kidney-293 cells | VEGF, vascular endothelial growth factor (vasoendothelial growth factor) | EF2K, elongation-factor-2 kinase | CK, casein kinase | PTEN, phosphatase and tensin homologue deleted on chromosome 10 | ERK, extracellular-signal-regulated kinase | ATM, ataxia telangiectasia mutated | SRPK, serine-arginine protein kinase | IL-1, interleukin 1 | MNK, MAPK-integrating protein kinase | ROCK, Rho-dependent protein kinase | CaMKK, CaMK kinase | GST, glutathione transferase | MKK1, MAPK kinase-1 (also called MEK1, MAPK or ERK kinase 1) | GAK, cyclin G-associated kinase | FMK, fluoromethylketone | MST, mammalian homologue Ste20-like kinase | PKA, cAMP-dependent protein kinase | FKBP, FK506-binding protein | PPAR, peroxisome-proliferator-activated receptor | IKK, inhibitory κB kinase | PH, pleckstrin homology | MBP, myelin basic protein | AICAR, aminoimidazole-4-carboxamide-1-β-D-ribofuranoside | MAPKAP-K, MAPK-activated protein kinase | Sf21, Spodoptera frugiperda (fall armyworm) 21 | MARK, microtubule-affinity-regulating kinase | PIM, provirus integration site for Moloney murine leukaemia virus | LPS, lipopolysaccharide | MSK, mitogen- and stress-activated protein kinase | MAPK, mitogen-activated protein kinase | MELK, maternal embryonic leucine-zipper kinase | His6, hexahistidine | CAK, cyclin-dependent kinase-activating kinase | Eph-A2, Ephrin A2 receptor | PLK, polo-like kinase | ATF2, activating transcription factor 2 | PKD, protein kinase D | Src, sarcoma kinase | AMPK, AMP-activated protein kinase | MMS, methyl methanesulfonate | CHK, checkpoint kinase | JNK, c-Jun N-terminal kinase | TORC1, mTOR (mammalian target of rapamycin)–raptor (regulatory associated protein of mTOR) complex | BRSK, brain-specific kinase | RIP2, receptor-interacting protein 2 | IGF-1, insulin-like growth factor-1 | S6K1, S6 kinase 1 | DYRK, dual-specificity tyrosine-phosphorylated and -regulated kinase | HIPK, homeodomain-interacting protein kinase | ZMP, aminoimidazole-4-carboxamide-1-β-D-ribofuranoside monophosphate | PRAK, p38-regulated activated kinase | PKC, protein kinase C | Src-I1, Src inhibitor 1 | TANK, TRAF (tumour-necrosis-factor-receptor-associated factor)-family-member-associated nuclear factor κB activator | NFAT, nuclear factor for activated T-cells | PHK, phosphorylase kinase | GSK3, glycogen synthase kinase 3 | PKB, protein kinase B (also called Akt) | CaMK, calmodulin-dependent kinase | CDK, cyclin-dependent protein kinase | NDRG, N-myc downstream-regulated gene | SmMLCK, smooth-muscle myosin light-chain kinase | TBK1, TANK-binding kinase 1 | PRK, protein kinase C-related kinase | SGK, serum- and glucocorticoid-induced kinase
Journal Article
Journal of Leukocyte Biology, ISSN 0741-5400, 09/2018, Volume 104, Issue 3, pp. 615 - 630
Neutrophils are important mediators of the innate immune defense and of the host response to a physical trauma. Because aberrant infiltration of injured sites... 
PMN | slingshot2 | motility | protein kinase D | actin | cofilin | PROTEIN-KINASE-D | INFLAMMATORY RESPONSES | PHOSPHORYLATION | CHEMOTAXIS | INVASIVE TUMOR-CELLS | LIM-KINASE | IMMUNOLOGY | INTESTINAL EPITHELIAL-CELLS | CELL BIOLOGY | COFILIN ACTIVITY | SLINGSHOT | HEMATOLOGY | PANCREATIC-CANCER CELLS | Index Medicus
Journal Article
IUBMB Life, ISSN 1521-6543, 04/2011, Volume 63, Issue 4, pp. spcone - spcone
Protein kinase D1/2 signaling in endothelial cells by Ian M. Evans and Ian C. Zachary, pp. 258–263. 
protein kinase D | cancer | VEGF | angiogenesis
Journal Article
Journal of Molecular and Cellular Cardiology, ISSN 0022-2828, 05/2018, Volume 118, pp. 13 - 25
Class IIa histone deacetylases (HDACs) are transcriptional repressors whose nuclear export in the cardiac myocyte is associated with the induction of... 
mAKAP | PKD | HDAC5 | Phosphorylation | Scaffold | PKA | TRANSCRIPTIONAL ACTIVITY | ACTIVATION | CARDIAC & CARDIOVASCULAR SYSTEMS | HISTONE DEACETYLASE 5 | PROTEIN-KINASE-D | HEART-FAILURE | MUSCLE | NUCLEAR EXPORT | CELL BIOLOGY | PHOSPHATIDYLINOSITOL 4-PHOSPHATE | AKAP-LBC | scaffold | phosphorylation
Journal Article