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Journal Article
Diabetes, ISSN 0012-1797, 03/2011, Volume 60, Issue 3, pp. 981 - 992
OBJECTIVE-Chronic hypoxia has been recognized as a key regulator in renal tubulointerstitial fibrosis, as seen in diabetic nephropathy, which is associated... 
HYPOXIA PROMOTES FIBROGENESIS | KIDNEY-DISEASE | INSULIN | RESPIRATORY-CHAIN | TO-MESENCHYMAL TRANSITION | ACTIVATED PROTEIN-KINASE | EPITHELIAL-CELLS | MITOCHONDRIAL COMPLEX-I | PATHWAY | ENDOCRINOLOGY & METABOLISM | GLUCOSE-TRANSPORT | Immunohistochemistry | Epithelial Cells - metabolism | Metformin - therapeutic use | Diabetes Mellitus, Type 2 - genetics | Epithelial Cells - drug effects | Humans | Male | Diabetes Mellitus, Type 2 - metabolism | Oxygen Consumption - physiology | Hypoxia-Inducible Factor 1, alpha Subunit - metabolism | Adenylate Kinase - metabolism | Diabetic Nephropathies - prevention & control | Hypoglycemic Agents - therapeutic use | Cell Line | Insulin - pharmacology | Hypoxia-Inducible Factor 1, alpha Subunit - genetics | Diabetic Nephropathies - metabolism | Metformin - pharmacology | Rats | Diabetic Nephropathies - genetics | Reverse Transcriptase Polymerase Chain Reaction | Hypoglycemic Agents - pharmacology | Rats, Zucker | Leupeptins - pharmacology | Animals | Analysis of Variance | Signal Transduction - drug effects | Oxygen Consumption - drug effects | Cysteine Proteinase Inhibitors - pharmacology | Kidney Tubules, Proximal - metabolism | Signal Transduction - physiology | Diabetes Mellitus, Type 2 - drug therapy | Adenylate Kinase - genetics | Insulin - therapeutic use | Kidney Tubules, Proximal - drug effects | Complications
Journal Article
Nature Immunology, ISSN 1529-2908, 07/2010, Volume 11, Issue 7, pp. 608 - 617
The mechanisms that initiate T helper type 2 (T(H)2) responses are poorly understood. Here we demonstrate that cysteine protease-induced T(H)2 responses occur... 
OXIDATIVE STRESS | IN-VIVO DEPLETION | IMMUNE-RESPONSES | DISTINCT | AIRWAY INFLAMMATION | IL-4 PRODUCTION | IMMUNOLOGY | THYMIC STROMAL LYMPHOPOIETIN | CUTTING EDGE | LANGERHANS CELLS | ANTIGEN | Epithelial Cells - metabolism | Langerhans Cells - pathology | Reactive Oxygen Species - metabolism | Th2 Cells - immunology | Adaptor Proteins, Vesicular Transport - metabolism | Interleukin-4 - biosynthesis | Basophils - pathology | Reactive Oxygen Species - immunology | Basophils - immunology | Langerhans Cells - immunology | Papain - immunology | Cytokines - genetics | Signal Transduction | Lymphocyte Activation | Mice, Inbred C57BL | Cell Communication | Epithelial Cells - pathology | Mice, Transgenic | Toll-Like Receptor 4 - metabolism | Mice, Knockout | Animals | Epithelial Cells - immunology | Antigens - immunology | Mice | Mice, Inbred BALB C | Basophils - metabolism | Langerhans Cells - metabolism | Cytokines - biosynthesis | Physiological aspects | Cellular signal transduction | Research | Active oxygen | T cells | Proteases | Cysteine | Epithelial cells | Interleukin | Helper cells | Cysteine proteinase | Lipids | Lymphocytes T | CD70 antigen | Lymph nodes | Thymus | Proteins | Interleukin 4 | Cooperation | Toll-like receptors | Immune system | Immunization | Lymphatic system | Dendritic cells | Papain | Interleukin 12 | TLR4 protein | Molecular chains | Signaling | Thymic stromal lymphopoietin | Skin | Leukocytes (basophilic) | Cell migration | Antigens | Interleukin-4 | Reactive Oxygen Species | Toll-Like Receptor 4 | Cytokines | Langerhans Cells | Epithelial Cells | Adaptor Proteins, Vesicular Transport | Th2 Cells | Life Sciences | Immunology | Basophils
Journal Article
Immunological Reviews, ISSN 0105-2896, 07/2017, Volume 278, Issue 1, pp. 162 - 172
Journal Article
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 2/2010, Volume 107, Issue 7, pp. 3076 - 3080
Journal Article
Biochemical Journal, ISSN 0264-6021, 03/2015, Volume 466, Issue 2, pp. 299 - 309
Journal Article
Arteriosclerosis, thrombosis, and vascular biology, ISSN 1079-5642, 2016, Volume 36, Issue 8, pp. 1647 - 1650
Journal Article