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Cancer Chemotherapy and Pharmacology, ISSN 0344-5704, 7/2016, Volume 78, Issue 1, pp. 41 - 49
The Hedgehog pathway inhibitor vismodegib exhibits pH-dependent solubility, and in vitro studies have shown that vismodegib is a substrate of P-glycoprotein... 
Medicine & Public Health | CYP inhibitors | Clinical pharmacology | Oncology | Cancer Research | Pharmacology/Toxicology | Clinical drug–drug interaction | Pharmacokinetic | Proton-pump inhibitor | P-glycoprotein inhibitor | SINGLE | HUMAN PLASMA | ORAL ABSORPTION | MASS-SPECTROMETRY | GDC-0449 | ONCOLOGY | Clinical drug-drug interaction | PHARMACOLOGY & PHARMACY | HEALTHY-VOLUNTEERS | HEDGEHOG SIGNALING PATHWAY | SOLID-PHASE EXTRACTION | Fluconazole - pharmacology | Proton Pump Inhibitors - pharmacology | Cytochrome P-450 CYP3A Inhibitors - administration & dosage | Pyridines - administration & dosage | Cytochrome P-450 CYP3A Inhibitors - pharmacology | Area Under Curve | Humans | ATP-Binding Cassette, Sub-Family B, Member 1 - metabolism | Fluconazole - administration & dosage | Solubility | Pyridines - pharmacokinetics | Anilides - pharmacokinetics | ATP-Binding Cassette, Sub-Family B, Member 1 - antagonists & inhibitors | Itraconazole - pharmacology | Cytochrome P-450 CYP2C9 Inhibitors - administration & dosage | Cytochrome P-450 CYP2C9 Inhibitors - pharmacology | Drug Interactions | Anilides - administration & dosage | Proton Pump Inhibitors - administration & dosage | Rabeprazole - pharmacology | Female | Itraconazole - administration & dosage | Hydrogen-Ion Concentration | Rabeprazole - administration & dosage | Drug interactions | Cytochrome P-450 | Index Medicus | Original
Journal Article
Journal of Allergy and Clinical Immunology, The, ISSN 0091-6749, 2014, Volume 135, Issue 1, pp. 187 - 197.e4
Journal Article
Journal of the American College of Cardiology, ISSN 0735-1097, 07/2010, Volume 56, Issue 2, pp. 134 - 143
Journal Article
Journal of Gastroenterology and Hepatology, ISSN 0815-9319, 03/2018, Volume 33, Issue 3, pp. 623 - 630
Journal Article
Circulation, ISSN 0009-7322, 02/2012, Volume 125, Issue 8, pp. 978 - 986
Journal Article
Lancet, The, ISSN 0140-6736, 2007, Volume 369, Issue 9573, pp. 1621 - 1626
Summary Background Guidelines on pain management recommend that patients at risk of ulcers receive either a cyclo-oxygenase (COX 2) inhibitor or a... 
Internal Medicine | ESOMEPRAZOLE | MEDICINE, GENERAL & INTERNAL | NONSTEROIDAL ANTIINFLAMMATORY DRUGS | NSAID | CYCLOOXYGENASE-2 INHIBITORS | ARTHRITIS PATIENTS | NAPROXEN | COMPLICATIONS | HELICOBACTER-PYLORI | PEPTIC-ULCER | CELECOXIB | Pyrazoles - therapeutic use | Humans | Esomeprazole - adverse effects | Male | Secondary Prevention | Osteoarthritis - drug therapy | Esomeprazole - therapeutic use | Peptic Ulcer Hemorrhage - prevention & control | Female | Drug Therapy, Combination | Pyrazoles - adverse effects | Anti-Ulcer Agents - therapeutic use | Double-Blind Method | Proton Pump Inhibitors | Risk Factors | Anti-Ulcer Agents - adverse effects | Peptic Ulcer Hemorrhage - chemically induced | Treatment Outcome | Celecoxib | Peptic Ulcer Hemorrhage - therapy | Anti-Inflammatory Agents, Non-Steroidal - adverse effects | Sulfonamides - therapeutic use | Anti-Inflammatory Agents, Non-Steroidal - therapeutic use | Sulfonamides - adverse effects | Aged | Cyclooxygenase Inhibitors - adverse effects | Cyclooxygenase Inhibitors - therapeutic use | Prevention | Complications and side effects | COX-2 inhibitors | Relapse | Gastrointestinal bleeding | Peptic ulcer | Proton pump inhibitors | Dosage and administration | Drug therapy | Diseases | Drugs | Medical research | Physical examinations | Hospitals | Analgesics | Ulcers | Terminal illnesses | Clinical trials | Pharmaceuticals | Index Medicus | Abridged Index Medicus
Journal Article
Clinical Gastroenterology and Hepatology, ISSN 1542-3565, 2016, Volume 14, Issue 6, pp. 809 - 815.e1
Journal Article
Journal Article