Articles

Search Articles

Advanced search
Help

Catalogue

Articles

Databases

X
Search Filters
Format Format
Format Format
X
Sort by Item Count (A-Z)
Filter by Count
Journal Article (4473) 4473
Publication (1111) 1111
Book Chapter (15) 15
Conference Proceeding (9) 9
Book Review (6) 6
Dissertation (5) 5
Magazine Article (5) 5
Book / eBook (1) 1
Paper (1) 1
more...
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
proviruses - genetics (2798) 2798
humans (2661) 2661
animals (2026) 2026
virology (1616) 1616
molecular sequence data (1364) 1364
base sequence (1230) 1230
viruses (1081) 1081
hiv-1 - genetics (982) 982
female (944) 944
proviruses (939) 939
index medicus (925) 925
proviruses - isolation & purification (882) 882
mice (857) 857
polymerase chain reaction (838) 838
male (822) 822
dna (769) 769
dna, viral - genetics (767) 767
cell line (736) 736
dna, viral - analysis (670) 670
research article (605) 605
immunology (604) 604
infectious diseases (591) 591
hiv (536) 536
hiv infections - virology (532) 532
infection (525) 525
adult (513) 513
virus replication (503) 503
amino acid sequence (494) 494
expression (487) 487
proviruses - physiology (468) 468
viral load (441) 441
hiv-1 - physiology (439) 439
research (421) 421
middle aged (405) 405
cells, cultured (393) 393
transfection (393) 393
cloning, molecular (386) 386
transcription, genetic (381) 381
microbiology (373) 373
retroviridae - genetics (369) 369
virus diseases (366) 366
hiv-1 - isolation & purification (364) 364
mutation (360) 360
biochemistry & molecular biology (358) 358
replication (353) 353
virus integration (350) 350
human-immunodeficiency-virus (347) 347
human t-lymphotropic virus 1 - genetics (339) 339
genes, viral (315) 315
hiv-1 (312) 312
rna (307) 307
multidisciplinary sciences (294) 294
long terminal repeat (292) 292
lymphocytes (291) 291
rna, viral - genetics (289) 289
hiv infections - drug therapy (288) 288
gene expression (287) 287
genome, viral (280) 280
cells (278) 278
polymerase chain reaction - methods (275) 275
aids (271) 271
genetics & heredity (267) 267
genetic aspects (265) 265
dna, viral - isolation & purification (261) 261
biotechnology & applied microbiology (260) 260
genetic vectors (255) 255
genomes (251) 251
analysis (244) 244
repetitive sequences, nucleic acid (244) 244
health aspects (243) 243
infections (242) 242
leukocytes, mononuclear - virology (242) 242
phylogeny (242) 242
sequence analysis, dna (241) 241
blotting, southern (240) 240
human t-lymphotropic virus 1 - isolation & purification (237) 237
cell biology (230) 230
identification (228) 228
dna, viral - blood (226) 226
gene (225) 225
gene expression regulation, viral (223) 223
genes (221) 221
sequences (221) 221
restriction mapping (220) 220
hiv-1 - drug effects (217) 217
recombination, genetic (216) 216
protein (212) 212
retrovirus (208) 208
type-1 (204) 204
immunodeficiency-virus type-1 (201) 201
in-vivo (201) 201
endogenous retroviruses - genetics (193) 193
aged (191) 191
proteins (191) 191
hiv infections - immunology (190) 190
hiv infection (189) 189
htlv-i (189) 189
plasmids (185) 185
leukemia virus, murine - genetics (184) 184
medicine, research & experimental (183) 183
more...
Library Location Library Location
Language Language
Language Language
X
Sort by Item Count (A-Z)
Filter by Count
English (4384) 4384
Japanese (30) 30
Russian (28) 28
French (20) 20
Spanish (12) 12
German (10) 10
Chinese (5) 5
Italian (1) 1
Portuguese (1) 1
Turkish (1) 1
Ukrainian (1) 1
more...
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


1. Full Text Conditional tolerance of temperate phages via transcription-dependent CRISPR-Cas targeting
by Goldberg, Gregory W and Jiang, Wenyan and Bikard, David and Marraffini, Luciano A
Nature, ISSN 0028-0836, 08/2014, Volume 514, Issue 7524, pp. 633 - 637
A fundamental feature of immune systems is the ability to distinguish pathogenic from self and commensal elements, and to attack the former but tolerate the... 
IMMUNITY | COMPLEX | ANTIVIRAL DEFENSE | PROTEIN | RNA | DNA | MULTIDISCIPLINARY SCIENCES | SEQUENCE | SYSTEMS | STAPHYLOCOCCUS-AUREUS | INTERFERENCE | Proviruses - physiology | Bacteriophages - pathogenicity | Staphylococcus epidermidis - immunology | Lysogeny - immunology | Molecular Sequence Data | Proviruses - immunology | Proviruses - genetics | Base Sequence | Bacteriophages - genetics | Transcription, Genetic | Clustered Regularly Interspaced Short Palindromic Repeats - genetics | Clustered Regularly Interspaced Short Palindromic Repeats - immunology | CRISPR-Associated Proteins - immunology | Lysogeny - genetics | CRISPR-Cas Systems - immunology | DNA, Viral - metabolism | Immune Tolerance | Proviruses - pathogenicity | CRISPR-Cas Systems - genetics | Bacteriophages - immunology | Staphylococcus epidermidis - genetics | DNA, Viral - immunology | CRISPR-Associated Proteins - metabolism | CRISPR-Cas Systems - physiology | Bacteriophages - physiology | DNA, Viral - genetics | Staphylococcus epidermidis - virology | Bacteriophages | Infection | Genetic research | Research | Genetic transcription | Health aspects | Immune system | Staphylococcus infections | Genomes | Efficiency | Bacteriology | Deoxyribonucleic acid--DNA
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
2. Full Text Defective HIV-1 Proviruses Are Expressed and Can Be Recognized by Cytotoxic T Lymphocytes, which Shape the Proviral Landscape
by Pollack, Ross A and Jones, R. Brad and Pertea, Mihaela and Bruner, Katherine M and Martin, Alyssa R and Thomas, Allison S and Capoferri, Adam A and Beg, Subul A and Huang, Szu-Han and Karandish, Sara and Hao, Haiping and Halper-Stromberg, Eitan and Yong, Patrick C and Kovacs, Colin and Benko, Erika and Siliciano, Robert F and Ho, Ya-Chi
Cell Host & Microbe, ISSN 1931-3128, 04/2017, Volume 21, Issue 4, pp. 494 - 506.e4
Despite antiretroviral therapy, HIV-1 persists in memory CD4 T cells, creating a barrier to cure. The majority of HIV-1 proviruses are defective and considered... 
APOBEC-mediated G-to-A hypermutations | defective HIV-1 proviruses | HIV-1 cure | alternative splicing | cold-target inhibition | HIV-1 latent reservoir | HIV-1 proviral landscape | cell-associated HIV-1 RNA | cytotoxic T lymphocytes | defective ribosomal product | SUPPRESSIVE ANTIRETROVIRAL THERAPY | ALTERNATIVE READING FRAMES | MICROBIOLOGY | MHC CLASS-I | VIROLOGY | MESSENGER-RNA | CELL SURVIVAL | IMMUNODEFICIENCY-VIRUS TYPE-1 | INFECTED PATIENTS | LATENT RESERVOIR | CD8(+) LYMPHOCYTES | PARASITOLOGY | VIRAL RESERVOIR | Genetic Variation | T-Lymphocytes, Cytotoxic - immunology | HIV-1 - immunology | HIV Infections - pathology | Proviruses - genetics | Proviruses - classification | HIV Infections - virology | Humans | Proviruses - immunology | HIV-1 - genetics | HIV-1 - classification | Highly active antiretroviral therapy | Antiviral agents | Medical colleges | Microbiology | T cells | HIV (Viruses) | Antigenic determinants
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
3. Full Text Relationship between intact HIV-1 proviruses in circulating CD4+ T cells and rebound viruses emerging during treatment interruption
by Lu, Ching-Lan and Lu, Ching-Lan and Pai, Joy A and Pai, Joy A and Nogueira, Lilian and Nogueira, Lilian and Mendoza, Pilar and Mendoza, Pilar and Gruell, Henning and Oliveira, Thiago Y and Oliveira, Thiago Y and Barton, John and Lorenzi, Julio C.C and Lorenzi, Julio C C and Cohen, Yehuda Z and Cohen, Yehuda Z and Cohn, Lillian B and Cohn, Lillian B and Klein, Florian and Caskey, Marina and Caskey, Marina and Nussenzweig, Michel C and Nussenzweig, Michel C and Jankovic, Mila and Jankovic, Mila
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 11/2018, Volume 115, Issue 48, pp. E11341 - E11348
Combination antiretroviral therapy controls but does not cure HIV-1 infection because a small fraction of cells harbor latent viruses that can produce rebound... 
Latent reservoir | HIV | Analytical treatment interruption | Sequencing | ANTIBODIES | RECOMBINATION | THERAPY | analytical treatment interruption | MULTIDISCIPLINARY SCIENCES | SEQUENCE | IDENTIFICATION | latent reservoir | sequencing | Antibodies, Neutralizing - administration & dosage | Proviruses - physiology | Proviruses - classification | Virus Latency | HIV Infections - virology | Humans | Phylogeny | HIV-1 - genetics | HIV Antibodies - administration & dosage | Proviruses - growth & development | HIV-1 - classification | Anti-HIV Agents - administration & dosage | HIV-1 - growth & development | HIV-1 - physiology | Proviruses - genetics | Virus Replication | HIV Infections - drug therapy | CD4-Positive T-Lymphocytes - virology | Biological Sciences | PNAS Plus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
4. Full Text Stimulation of HIV-1-Specific Cytolytic T Lymphocytes Facilitates Elimination of Latent Viral Reservoir after Virus Reactivation
by Shan, Liang and Deng, Kai and Shroff, Neeta S and Durand, Christine M and Rabi, S. Alireza and Yang, Hung-Chih and Zhang, Hao and Margolick, Joseph B and Blankson, Joel N and Siliciano, Robert F
Immunity, ISSN 1074-7613, 03/2012, Volume 36, Issue 3, pp. 491 - 501
Highly active antiretroviral therapy (HAART) suppresses HIV-1 replication but cannot eliminate the virus because HIV-1 establishes latent infection.... 
IN-VITRO SYSTEM | VIREMIA | HIV-INFECTION | IMMUNOLOGICAL CONTROL | CYTOTOXIC LYMPHOCYTES | ACTIVE ANTIRETROVIRAL THERAPY | GENE-EXPRESSION | VALPROIC ACID | HIV-1-INFECTED PATIENTS | IMMUNOLOGY | CELL DEPLETION | T-Lymphocytes, Cytotoxic - immunology | Proviruses - physiology | HIV-1 - pathogenicity | HIV-1 - drug effects | Lymphocyte Activation | Coculture Techniques | HIV Infections - virology | Humans | Cytopathogenic Effect, Viral | Proviruses - immunology | Antiretroviral Therapy, Highly Active | CD4-Positive T-Lymphocytes - immunology | HIV Infections - immunology | Proviruses - drug effects | HIV-1 - immunology | HIV-1 - physiology | Virus Replication | HIV Infections - drug therapy | CD4-Positive T-Lymphocytes - virology | Virus Latency - immunology | CD4-Positive T-Lymphocytes - drug effects | Cytotoxicity, Immunologic | Virus diseases | Highly active antiretroviral therapy | Antiviral agents | Medical colleges | Lymphocytes | Analysis | HIV (Viruses) | T cells | Health aspects | Public health | Studies | Acquired immune deficiency syndrome--AIDS | Human immunodeficiency virus--HIV | Viruses | Infections | Gene expression | Patients | Immune system | Apoptosis
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
5. Full Text Administration of vorinostat disrupts HIV-1 latency in patients on antiretroviral therapy
by Archin, N.M and Liberty, A.L and Kashuba, A.D and Choudhary, S.K and Kuruc, J.D and Crooks, A.M and Parker, D.C and Anderson, E.M and Kearney, M.F and Strain, M.C and Richman, D.D and Hudgens, M.G and Bosch, R.J and Coffin, J.M and Eron, J.J and Hazuda, D.J and Margolis, D.M
Nature, ISSN 0028-0836, 07/2012, Volume 487, Issue 7408, pp. 482 - 485
Despite antiretroviral therapy, proviral latency of human immunodeficiency virus type 1 (HIV-1) remains a principal obstacle to curing the infection(1).... 
CELLS | ACTIVATION | SUBEROYLANILIDE HYDROXAMIC ACID | MULTIDISCIPLINARY SCIENCES | IN-VIVO | VALPROIC ACID | INFECTION | HISTONE DEACETYLASE INHIBITORS | TYPE-1 | EXPRESSION | PCR | Gene Expression Regulation, Viral - drug effects | Humans | Hydroxamic Acids - adverse effects | Histone Deacetylase Inhibitors - administration & dosage | RNA, Viral - blood | Virus Latency - drug effects | Proviruses - drug effects | HIV-1 - growth & development | Proviruses - genetics | Hydroxamic Acids - administration & dosage | Anti-HIV Agents - therapeutic use | CD4-Positive T-Lymphocytes - virology | Hydroxamic Acids - pharmacology | Biomarkers - metabolism | HIV Infections - blood | Risk Assessment | HIV-1 - drug effects | CD4-Positive T-Lymphocytes - cytology | HIV Infections - virology | RNA, Viral - biosynthesis | CD4-Positive T-Lymphocytes - metabolism | Viremia - drug therapy | HIV-1 - genetics | Proviruses - growth & development | Histones - drug effects | Up-Regulation - drug effects | Acetylation - drug effects | Viremia - virology | HIV Infections - drug therapy | Histone Deacetylase Inhibitors - pharmacology | Histones - metabolism | CD4-Positive T-Lymphocytes - drug effects | Histone Deacetylase Inhibitors - adverse effects | Physiological aspects | Antiviral agents | HIV patients | Health aspects | Vorinostat | Antiretroviral drugs | Plasma | Cell culture | Lymphocytes | Human immunodeficiency virus--HIV | Genomes | Drug therapy | Drug dosages
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
6. Full Text HIV-1 antibody 3BNC117 suppresses viral rebound in humans during treatment interruption
by Scheid, Johannes F and Horwitz, Joshua A and Bar-On, Yotam and Kreider, Edward F and Lu, Ching-Lan and Lorenzi, Julio C. C and Feldmann, Anna and Braunschweig, Malte and Nogueira, Lilian and Oliveira, Thiago and Shimeliovich, Irina and Patel, Roshni and Burke, Leah and Cohen, Yehuda Z and Hadrigan, Sonya and Settler, Allison and Witmer-Pack, Maggi and West, Anthony P and Juelg, Boris and Keler, Tibor and Hawthorne, Thomas and Zingman, Barry and Gulick, Roy M and Pfeifer, Nico and Learn, Gerald H and Seaman, Michael S and Bjorkman, Pamela J and Klein, Florian and Schlesinger, Sarah J and Walker, Bruce D and Hahn, Beatrice H and Nussenzweig, Michel C and Caskey, Marina
Nature, ISSN 0028-0836, 07/2016, Volume 535, Issue 7613, pp. 556 - 560
Interruption of combination antiretroviral therapy in HIV-1-infected individuals leads to rapid viral rebound. Here we report the results of a phase IIa open... 
POTENT | REPLICATION | GENETIC-DETERMINANTS | BROADLY NEUTRALIZING ANTIBODIES | MULTIDISCIPLINARY SCIENCES | PASSIVE TRANSFER | SEQUENCE | CD4 BINDING | ANTIRETROVIRAL THERAPY | INFECTION | MONOCLONAL-ANTIBODIES | Anti-HIV Agents - pharmacology | Antibodies, Neutralizing - administration & dosage | Disease Reservoirs - virology | Humans | Middle Aged | Male | Proviruses - immunology | Anti-HIV Agents - administration & dosage | Tissue Distribution | Young Adult | HIV Infections - immunology | Proviruses - drug effects | Antibodies, Neutralizing - immunology | HIV-1 - growth & development | HIV Antibodies - immunology | HIV Envelope Protein gp160 - chemistry | Time Factors | Antibodies, Neutralizing - therapeutic use | Binding Sites - immunology | Adult | Anti-HIV Agents - therapeutic use | Female | HIV Antibodies - therapeutic use | Historically Controlled Study | Binding Sites - drug effects | HIV Envelope Protein gp160 - metabolism | Drug Administration Schedule | HIV-1 - drug effects | HIV Infections - virology | HIV Antibodies - administration & dosage | Viral Load - immunology | Proviruses - growth & development | HIV-1 - immunology | HIV Envelope Protein gp160 - antagonists & inhibitors | Adolescent | HIV Infections - drug therapy | Aged | HIV Envelope Protein gp160 - immunology | Viral Load - drug effects | CD4 Antigens - metabolism | Prevention | Antiviral agents | HIV antibodies | Dosage and administration | Host-virus relationships | Drug therapy, Combination | Drug therapy | Health aspects | HIV infection | Methods | Clinical trials | Antiretroviral drugs | Immunoglobulins | Human immunodeficiency virus--HIV | Binding sites
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
7. Full Text Total HIV-1 DNA, a marker of viral reservoir dynamics with clinical implications
by Avettand-Fènoë, Véronique and Hocqueloux, Laurent and Ghosn, Jade and Cheret, Antoine and Frange, Pierre and Melard, Adeline and Viard, Jean-Paul and Rouzioux, Christine
Clinical Microbiology Reviews, ISSN 0893-8512, 10/2016, Volume 29, Issue 4, pp. 859 - 880
HIV-1 DNApersists in infected cells despite combined antiretroviral therapy (cART), forming viral reservoirs. Recent trials of strategies targeting latent HIV... 
REAL-TIME PCR | LONG-TERM NONPROGRESSORS | STRUCTURED TREATMENT INTERRUPTIONS | DROPLET DIGITAL PCR | ACTIVE ANTIRETROVIRAL THERAPY | IMMUNE ACTIVATION | CD4(+) T-CELLS | MICROBIOLOGY | PERIPHERAL-BLOOD | VIRUS TYPE-1 INFECTION | BLOOD MONONUCLEAR-CELLS | Proviruses - physiology | Proviruses - isolation & purification | Virus Latency | HIV Infections - virology | Humans | DNA, Viral - analysis | HIV-1 - genetics | Viral Load | HIV-1 - physiology | Proviruses - genetics | HIV-1 - isolation & purification | Biomarkers | DNA, Viral - genetics | Reviews
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
8. Full Text CD32a is a marker of a CD4 T-cell HIV reservoir harbouring replication-competent proviruses
by Descours, Benjamin and Petitjean, Gaël and López-Zaragoza, José-Luis and Bruel, Timothée and Raffel, Raoul and Psomas, Christina and Reynes, Jacques and Lacabaratz, Christine and Levy, Yves and Schwartz, Olivier and Lelievre, Jean Daniel and Benkirane, Monsef
Nature, ISSN 0028-0836, 03/2017, Volume 543, Issue 7646, pp. 564 - 567
The persistence of the HIV reservoir in infected individuals is a major obstacle to the development of a cure for HIV1-3. Here, using an in vitro model of... 
FC-GAMMA RECEPTORS | INTEGRATION | BROADLY NEUTRALIZING ANTIBODIES | MACROPHAGES | MULTIDISCIPLINARY SCIENCES | ACTIVE ANTIRETROVIRAL THERAPY | INFECTION | LATENT RESERVOIR | SAMHD1 | VPX | Proviruses - isolation & purification | Humans | DNA, Viral - analysis | Gene Expression Profiling | Virus Latency - drug effects | Receptors, IgG - metabolism | HIV Infections - immunology | HIV-1 - growth & development | Proviruses - genetics | HIV-1 - isolation & purification | Cell Division | HEK293 Cells | Anti-HIV Agents - therapeutic use | CD4-Positive T-Lymphocytes - virology | HIV Infections - blood | Cell Separation | CD4-Positive T-Lymphocytes - cytology | HIV Infections - virology | CD4-Positive T-Lymphocytes - metabolism | Cells, Cultured | Up-Regulation - genetics | HIV-1 - genetics | Proviruses - growth & development | Virus Replication | HIV Infections - drug therapy | Virus Latency - immunology | Virus Latency - genetics | T cells | HIV (Viruses) | Health aspects | Proteins | Lymphocytes | Human immunodeficiency virus--HIV | Gene expression | Viral infections | Deoxyribonucleic acid--DNA | Virology | Life Sciences | Human health and pathology
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
9. Full Text Comparative Analysis of Measures of Viral Reservoirs in HIV-1 Eradication Studies
by Eriksson, Susanne and Graf, Erin H and Dahl, Viktor and Strain, Matthew C and Yukl, Steven A and Lysenko, Elena S and Bosch, Ronald J and Lai, Jun and Chioma, Stanley and Emad, Fatemeh and Abdel-Mohsen, Mohamed and Hoh, Rebecca and Hecht, Frederick and Hunt, Peter and Somsouk, Ma and Wong, Joseph and Johnston, Rowena and Siliciano, Robert F and Richman, Douglas D and O'Doherty, Una and Palmer, Sarah and Deeks, Steven G and Siliciano, Janet D
PLoS Pathogens, ISSN 1553-7366, 02/2013, Volume 9, Issue 2, p. e1003174
HIV-1 reservoirs preclude virus eradication in patients receiving highly active antiretroviral therapy (HAART). The best characterized reservoir is a small,... 
LOW-LEVEL VIREMIA | PLASMA VIREMIA | CD4(+) T-CELLS | MICROBIOLOGY | PERIPHERAL-BLOOD | BLOOD MONONUCLEAR-CELLS | LATENT HIV-1 | INFECTED INDIVIDUALS | VIROLOGY | ACTIVE ANTIRETROVIRAL THERAPY | IN-VIVO | IMMUNODEFICIENCY-VIRUS TYPE-1 | PARASITOLOGY | Proviruses - isolation & purification | Disease Reservoirs - virology | Humans | Middle Aged | DNA, Viral - analysis | Male | Leukocytes, Mononuclear - virology | RNA, Viral - genetics | Proviruses - genetics | Virus Integration - drug effects | Polymerase Chain Reaction | Adult | Female | DNA, Viral - drug effects | Leukocytes, Mononuclear - drug effects | HIV Infections - genetics | HIV Infections - virology | RNA, Viral - analysis | HIV - isolation & purification | Proviruses - growth & development | HIV - growth & development | Antiretroviral Therapy, Highly Active | HIV - genetics | HIV Infections - drug therapy | Aged | DNA, Viral - genetics | RNA, Viral - drug effects | Viral Load - drug effects | Longitudinal Studies | CD4-Positive T-Lymphocytes - drug effects | Physiological aspects | HIV patients | Virulence (Microbiology) | Research | T cells | Health aspects | Plasma | Clinical trials | Statistical methods | Infections | Genomes | Grants | Experiments | Acquired immune deficiency syndrome--AIDS | Lymphocytes | Normal distribution | Human immunodeficiency virus--HIV | Drug therapy | Deoxyribonucleic acid--DNA | AIDS | HIV | Acquired immune deficiency syndrome | Deoxyribonucleic acid | DNA | Human immunodeficiency virus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights