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Haematologica, ISSN 0390-6078, 02/2019, Volume 104, Issue 3, pp. 609 - 621
Hyper-IgE syndromes comprise a group of inborn errors of immunity. STAT3-deficient hyper-IgE syndrome is characterized by elevated serum IgE levels, recurrent... 
COMBINED IMMUNODEFICIENCY | CYTOKINE PRODUCTION | DEDICATOR | STAT3 | PROXIMAL EXTRACELLULAR DOMAINS | LEUKEMIA INHIBITORY FACTOR | MUTATIONS | HEMATOLOGY | DEFICIENCY | SIGNAL TRANSDUCER | TH1 DIFFERENTIATION
Journal Article
Journal Article
Molecular Cell, ISSN 1097-2765, 2008, Volume 31, Issue 5, pp. 737 - 748
Journal Article
European Journal of Human Genetics, ISSN 1018-4813, 01/2010, Volume 18, Issue 1, pp. 26 - 32
Journal Article
International Journal of Oncology, ISSN 1019-6439, 2017, Volume 51, Issue 1, pp. 145 - 157
Dominant-activating mutations in the RET (rear-ranged during transfection) proto-oncogene, which encodes a receptor tyrosine kinase, is often associated with... 
RET | Ellipticine | Medullary thyroid carcinoma | G-quadruplex | EXTRACELLULAR DOMAIN | ellipticine | BINDING PROTEIN | PAPILLARY CARCINOMAS | PROXIMAL PROMOTER REGION | POLYMERASE STOP ASSAY | G-QUADRUPLEX STRUCTURES | ONCOLOGY | SIGNALING PATHWAY | PROGRESSIVE MEDULLARY | medullary thyroid carcinoma | RECEPTOR TYROSINE KINASE | I-MOTIF STRUCTURES | Carbazoles - chemistry | Proto-Oncogene Proteins c-ret - metabolism | Apoptosis - drug effects | Pyridines - chemistry | Humans | Male | Biomarkers, Tumor | Carcinoma, Papillary - metabolism | Piperidines - pharmacology | G-Quadruplexes | Antineoplastic Agents - pharmacology | Tumor Cells, Cultured | Ellipticines - chemistry | Proto-Oncogene Proteins c-ret - antagonists & inhibitors | Pyridines - therapeutic use | Carcinoma, Neuroendocrine - metabolism | Piperidines - chemistry | Carcinoma, Neuroendocrine - drug therapy | Ellipticines - pharmacology | Carcinoma, Papillary - drug therapy | Antineoplastic Agents - chemistry | Mice, SCID | Carcinoma, Papillary - pathology | Xenograft Model Antitumor Assays | Animals | Signal Transduction - drug effects | Thyroid Neoplasms - drug therapy | Carcinoma, Neuroendocrine - pathology | Piperidines - therapeutic use | Carbazoles - therapeutic use | Cell Proliferation - drug effects | Mice | Pyridines - pharmacology | Carbazoles - pharmacology | Proto-Oncogene Proteins c-ret - genetics | Thyroid Neoplasms - metabolism | Thyroid Neoplasms - pathology | Cell proliferation | Care and treatment | Research | Pharmacokinetics | Thyroid diseases | Proteins | Phosphorylation | Thyroid cancer | Rodents | Ligands | Metastasis | Mutation | Gene expression | Kinases | Deoxyribonucleic acid--DNA
Journal Article
Journal Article