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Trends in biochemical sciences (Amsterdam. Regular ed.), ISSN 0968-0004, 2014, Volume 39, Issue 4, pp. 183 - 190
Journal Article
Journal Article
Cancer research (Chicago, Ill.), ISSN 1538-7445, 2011, Volume 71, Issue 3, pp. 629 - 633
The importance of PTEN (phosphatase and tensin homolog located on chromosome 10) in cancer has surpassed all predictions and expectations from the time it was... 
NUCLEAR PTEN | GENE | ONCOLOGY | HEMATOPOIETIC STEM-CELLS | PROSTATE-CANCER | MUTATION | EXPRESSION | PTEN/MMAC1 | BREAST | PTEN Phosphohydrolase - genetics | Animals | Neoplasms - genetics | Humans | PTEN Phosphohydrolase - biosynthesis | Neoplasms - enzymology | PTEN Phosphohydrolase - metabolism | Mice | Neoplasms - pathology | Genes, Tumor Suppressor
Journal Article
PLoS biology, ISSN 1545-7885, 2009, Volume 7, Issue 6, p. e1000121
Journal Article
Journal of allergy and clinical immunology, ISSN 0091-6749, 2017, Volume 139, Issue 2, pp. 607 - 620.e15
Background Patients with heterozygous germline mutations in phosphatase and tensin homolog deleted on chromosome 10 (PTEN) experience autoimmunity and lymphoid... 
Allergy and Immunology | PHTS | autoimmunity | immunologic synapse | PTEN | Regulatory T cells | PH domain leucine-rich repeat protein phosphatase | phosphatases | phosphoinositide 3-kinase | HOMEOSTASIS | PROTEIN | KINASE | PROMOTER MUTATIONS | RILEY-RUVALCABA-SYNDROME | IMMUNOLOGY | ALLERGY | RESOLUTION MELTING ANALYSIS | AKT-MTOR | LYMPHOID HYPERPLASIA | EXPRESSION | Autoimmunity | Humans | Hyperplasia | Middle Aged | Phosphoprotein Phosphatases - metabolism | Male | Immunological Synapses - metabolism | Young Adult | Forkhead Transcription Factors - metabolism | Membrane Potential, Mitochondrial | Adult | Child | Hamartoma Syndrome, Multiple - immunology | Lymphocyte Subsets - physiology | T-Lymphocytes, Regulatory - physiology | PTEN Phosphohydrolase - genetics | Hamartoma Syndrome, Multiple - genetics | Signal Transduction | Cells, Cultured | B-Lymphocytes - physiology | PTEN Phosphohydrolase - metabolism | Nuclear Proteins - metabolism | Mutation - genetics | Protein Transport | Adolescent | Protein Binding | Aged | Medical colleges | Care and treatment | Phosphatases | Gene mutations | Analysis | Children's hospitals | Genomics | Medical genetics | Genetic research | T cells | Tumors | Hamartoma | Proteins | Blood & organ donations | Hematology | Biopsy | Lymphocytes | T cell receptors | Mutation | Kinases | Metabolism | Phosphatase | FACS, Fluorescence-activated cell sorting | TCR, T-cell receptor | mTOR complex 1 | NHERF1, Na+ | H+-exchanger 3 regulatory factor | MALT, Mucosa-associated lymphoid tissue | APC, Allophycocyanin | SHIP, Src homology domain 2–containing inositol phosphatase | HRM, High Resolution DNA Melting | FITC, Fluorescein isothiocyanate | PP2A, Protein phosphatase 2A | mTORC1, PTEN | PHTS, PTEN hamartoma tumor syndrome | PerCP, Peridinin-chlorophyll-protein complex | CS, Cowden syndrome | POD, Peroxidase | Tmem, Memory T | TMRE, Tetramethylrhodamine-ethylester | Immune Deficiencies, Infection, and Systemic Immune Disorders | IC50, Inhibitory concentration of 50 | CTLA-4, Cytotoxic T lymphocyte–associated antigen 4 | PHLPP, PH domain leucine-rich repeat protein phosphatase | AKT | DLG1, Scaffold protein discs, large homolog 1 | FOXP3, Forkhead box P3 | ICAM-1, Intercellular adhesion molecule 1 | iTreg, In vitro induced regulatory T | PE, Phycoerythrin | PI3K, Phosphoinositide 3-kinase | mTOR, Mammalian target of rapamycin | PTEN, Phosphatase and tensin homologue deleted on chromosome 10
Journal Article
Molecules (Basel, Switzerland), ISSN 1420-3049, 2018, Volume 23, Issue 2, p. 285
The tumor suppressor PTEN is a major homeostatic regulator, by virtue of its lipid phosphatase activity against phosphatidylinositol 3,4,5-trisphosphate... 
Stem-cells | Wound healing | Tissue injury | Small molecule pten inhibitor | Infertility | Diabetes | Pain relief | Neuroregeneration | Response to infection | Cancer | wound healing | BIOCHEMISTRY & MOLECULAR BIOLOGY | stem-cells | PROTEIN-TYROSINE PHOSPHATASES | infertility | TUMOR-SUPPRESSOR PTEN | small molecule PTEN inhibitor | TAU-PHOSPHORYLATION | CHROMOSOME-10 PTEN | CHEMISTRY, MULTIDISCIPLINARY | response to infection | ISCHEMIA-REPERFUSION INJURY | neuroregeneration | tissue injury | REDOX REGULATION | CORTICOSPINAL TRACT AXONS | TENSIN HOMOLOG PTEN | ENHANCES REGENERATIVE GROWTH | cancer | SPINAL-CORD-INJURY | diabetes | pain relief | Cell Survival - drug effects | Phosphatidylinositol Phosphates - metabolism | TOR Serine-Threonine Kinases - metabolism | Humans | PTEN Phosphohydrolase - metabolism | Myocardial Ischemia - enzymology | Phosphatidylinositol 3-Kinases - metabolism | Neurodegenerative Diseases - drug therapy | Enzyme Inhibitors - therapeutic use | Myocardial Ischemia - drug therapy | PTEN Phosphohydrolase - antagonists & inhibitors | Enzyme Inhibitors - chemistry | Cell Proliferation - drug effects | Proto-Oncogene Proteins c-akt - metabolism | Wound Healing - drug effects | Neurodegenerative Diseases - enzymology | TOR protein | Cell survival | Phosphatidylinositol 3,4,5-triphosphate | AKT protein | Catalytic activity | Kinases | Phosphatase | 1-Phosphatidylinositol 3-kinase | Phosphatidylinositol | Regeneration | Signaling | Molecular modelling | Ischemia | Enzymatic activity | Tumor suppressor genes | Protein phosphatase | Catalysis | Inhibition | Heart diseases | PTEN protein
Journal Article
Journal of clinical oncology, ISSN 1527-7755, 2013, Volume 31, Issue 34, pp. 4333 - 4342
Journal Article