X
Search Filters
Format Format
Format Format
X
Sort by Item Count (A-Z)
Filter by Count
Journal Article (9926) 9926
Publication (1424) 1424
Book Review (1360) 1360
Book Chapter (94) 94
Dissertation (36) 36
Conference Proceeding (31) 31
Government Document (20) 20
Data Set (3) 3
Web Resource (3) 3
Newspaper Article (2) 2
Book / eBook (1) 1
Paper (1) 1
more...
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
index medicus (8106) 8106
humans (6654) 6654
pten (4602) 4602
oncology (3455) 3455
animals (3249) 3249
female (3076) 3076
cancer (2905) 2905
pten phosphohydrolase - genetics (2865) 2865
mutation (2650) 2650
male (2407) 2407
pten phosphohydrolase - metabolism (2315) 2315
mice (2164) 2164
cell biology (1845) 1845
expression (1843) 1843
signal transduction (1804) 1804
pten protein (1561) 1561
tumors (1550) 1550
cell line, tumor (1516) 1516
middle aged (1494) 1494
apoptosis (1471) 1471
biochemistry & molecular biology (1431) 1431
genetic aspects (1398) 1398
phosphorylation (1354) 1354
proteins (1324) 1324
research (1236) 1236
gene expression (1235) 1235
adult (1231) 1231
proto-oncogene proteins c-akt - metabolism (1193) 1193
article (1186) 1186
aged (1181) 1181
kinases (1143) 1143
analysis (1116) 1116
gene (1073) 1073
phosphatidylinositol 3-kinases - metabolism (1073) 1073
pten phosphohydrolase (1061) 1061
mutations (1038) 1038
activation (1015) 1015
immunohistochemistry (978) 978
akt (936) 936
pathway (927) 927
cell proliferation (911) 911
gene expression regulation, neoplastic (875) 875
prognosis (872) 872
genetics & heredity (855) 855
genes (840) 840
tumor-suppressor (834) 834
breast cancer (823) 823
pathology (819) 819
metastasis (818) 818
multidisciplinary sciences (812) 812
growth (793) 793
phosphatase (768) 768
health aspects (763) 763
phosphoric monoester hydrolases - genetics (750) 750
carcinoma (740) 740
cells (715) 715
development and progression (709) 709
research article (691) 691
phosphatidylinositol 3-kinases - genetics (679) 679
prostate cancer (671) 671
akt protein (660) 660
phosphatases (652) 652
breast-cancer (647) 647
tumor-suppressor gene (637) 637
medicine (631) 631
tumor suppressor proteins - genetics (603) 603
survival (601) 601
prostate-cancer (598) 598
care and treatment (596) 596
physiological aspects (582) 582
cell cycle (569) 569
biology (559) 559
genetics (541) 541
cell growth (535) 535
protein (525) 525
tumor suppressor genes (520) 520
1-phosphatidylinositol 3-kinase (517) 517
tumor-suppressor pten (516) 516
inhibition (506) 506
pi3k (497) 497
signal transduction - drug effects (493) 493
tumorigenesis (491) 491
chemotherapy (484) 484
aged, 80 and over (483) 483
medicine, research & experimental (481) 481
mice, knockout (468) 468
science (468) 468
rodents (460) 460
breast neoplasms - genetics (452) 452
progression (451) 451
p53 (448) 448
proliferation (445) 445
genes, tumor suppressor (432) 432
tumor suppressor proteins (431) 431
breast (429) 429
down-regulation (421) 421
proto-oncogene proteins c-akt - genetics (420) 420
disease models, animal (419) 419
microrna (418) 418
neurosciences (415) 415
more...
Library Location Library Location
Language Language
Language Language
X
Sort by Item Count (A-Z)
Filter by Count
English (9891) 9891
Chinese (40) 40
Japanese (28) 28
French (22) 22
German (17) 17
Korean (8) 8
Polish (7) 7
Russian (7) 7
Spanish (6) 6
Turkish (4) 4
Czech (3) 3
Danish (3) 3
Hungarian (2) 2
Persian (1) 1
Slovak (1) 1
more...
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


Oncogene, ISSN 0950-9232, 09/2013, Volume 32, Issue 37, pp. 4417 - 4426
Journal Article
Journal of Allergy and Clinical Immunology, The, ISSN 0091-6749, 2016, Volume 138, Issue 6, pp. 1672 - 1680.e10
Journal Article
Clinical Cancer Research, ISSN 1078-0432, 05/2012, Volume 18, Issue 9, pp. 2704 - 2714
Journal Article
Science, ISSN 0036-8075, 11/2013, Volume 342, Issue 6160, pp. 866 - 871
Journal Article
Journal Article
Journal Article
Lung Cancer, ISSN 0169-5002, 2009, Volume 69, Issue 3, pp. 279 - 283
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 6/2010, Volume 107, Issue 22, pp. 10208 - 10213
PIK3CA mutations are reported to be present in approximately 25% of breast cancer (BC), particularly the estrogen receptor—positive (ER+) and... 
Datasets | Health outcomes | Prognosis | Cell lines | Breast cancer | Signatures | Gene expression | Genetic mutation | Tumors | Cancer | Gene expression profiling | PI3 kinase | MOLECULAR SUBTYPES | TYROSINE PHOSPHORYLATION | MULTIDISCIPLINARY SCIENCES | PTEN | 3-KINASE MUTATIONS | AKT | EXPRESSION PROFILES | TUMORS | INSULIN-RECEPTOR | PATHWAY | POOR-PROGNOSIS | gene expression profiling | Neoplasms, Hormone-Dependent - metabolism | Receptors, Estrogen - metabolism | Oligonucleotide Array Sequence Analysis | Humans | Multiprotein Complexes | Receptor, ErbB-2 - metabolism | DNA Primers - genetics | Gene Expression Profiling | Proto-Oncogene Proteins c-akt - genetics | Breast Neoplasms - metabolism | Mechanistic Target of Rapamycin Complex 1 | Neoplasms, Hormone-Dependent - genetics | Proteins | Antineoplastic Agents, Hormonal - therapeutic use | Base Sequence | Female | Sirolimus - therapeutic use | Signal Transduction | Breast Neoplasms - drug therapy | Phosphatidylinositol 3-Kinases - genetics | Transcription Factors - metabolism | Breast Neoplasms - genetics | Class I Phosphatidylinositol 3-Kinases | Antibiotics, Antineoplastic - therapeutic use | Tamoxifen - therapeutic use | Cell Line, Tumor | TOR Serine-Threonine Kinases | Mutation | Neoplasms, Hormone-Dependent - drug therapy | Receptors | Analysis | Estrogen | Genetic aspects | Research | Properties | Tamoxifen | Protein kinases | Health aspects | Genotype & phenotype | Oncology | Kinases | Clinical outcomes | Index Medicus | TOR protein | Transformation | Exons | Estrogens | AKT protein | Data processing | 1-Phosphatidylinositol 3-kinase | Signal transduction | Biological Sciences
Journal Article
Journal Article
by McRae, Jeremy F and Clayton, Stephen and Fitzgerald, Tomas W and Kaplanis, Joanna and Prigmore, Elena and Rajan, Diana and Sifrim, Alejandro and Aitken, Stuart and Akawi, Nadia and Alvi, Mohsan and Ambridge, Kirsty and Barrett, Daniel M and Bayzetinova, Tanya and Jones, Philip and Jones, Wendy D and King, Daniel and Krishnappa, Netravathi and Mason, Laura E and Singh, Tarjinder and Tivey, Adrian R and Ahmed, Munaza and Anjum, Uruj and Archer, Hayley and Armstrong, Ruth and Awada, Jana and Balasubramanian, Meena and Banka, Siddharth and Baralle, Diana and Barnicoat, Angela and Batstone, Paul and Baty, David and Bennett, Chris and Berg, Jonathan and Bernhard, Birgitta and Bevan, A. Paul and Bitner-Glindzicz, Maria and Blair, Edward and Blyth, Moira and Bohanna, David and Bourdon, Louise and Bourn, David and Bradley, Lisa and Brady, Angela and Brent, Simon and Brewer, Carole and Brunstrom, Kate and Bunyan, David J and Burn, John and Canham, Natalie and Castle, Bruce and Chandler, Kate and Chatzimichali, Elena and Cilliers, Deirdre and Clarke, Angus and Clasper, Susan and Clayton-Smith, Jill and Clowes, Virginia and Coates, Andrea and Cole, Trevor and Colgiu, Irina and Collins, Amanda and Collinson, Morag N and Connell, Fiona and Cooper, Nicola and Cox, Helen and Cresswell, Lara and Cross, Gareth and Crow, Yanick and D'Alessandro, Mariella and Dabir, Tabib and Davidson, Rosemarie and Davies, Sally and De Vries, Dylan and Dean, John and Deshpande, Charu and Devlin, Gemma and Dixit, Abhijit and Dobbie, Angus and Donaldson, Alan and Donnai, Dian and Donnelly, Deirdre and Donnelly, Carina and Douglas, Angela and Douzgou, Sofia and Duncan, Alexis and Eason, Jacqueline and Ellard, Sian and Ellis, Ian and Elmslie, Frances and Evans, Karenza and Everest, Sarah and Fendick, Tina and Fisher, Richard and Flinter, Frances and Foulds, Nicola and Fry, Andrew and Fryer, Alan and Gardiner, Carol and Gaunt, Lorraine and Ghali, Neeti and ... and Deciphering Developmental Disorders Study
Nature, ISSN 0028-0836, 02/2017, Volume 542, Issue 7642, pp. 433 - 438
The genomes of individuals with severe, undiagnosed developmental disorders are enriched in damaging de novo mutations (DNMs) in developmentally important... 
INTELLECTUAL DISABILITY | METAANALYSIS | VARIANTS | GENETICS | HEART-DEFECTS | MULTIDISCIPLINARY SCIENCES | GENES | SEQUENCE | FRAMEWORK | DISCOVERY | GENOME | Prevalence | Humans | Middle Aged | Parents | Male | Mi-2 Nucleosome Remodeling and Deacetylase Complex - genetics | Developmental Disabilities - genetics | Casein Kinase II - genetics | Autoantigens - genetics | Young Adult | ras GTPase-Activating Proteins - genetics | Adult | Female | Child | CDC2 Protein Kinase - genetics | Histone-Lysine N-Methyltransferase - genetics | Repressor Proteins - genetics | Sex Characteristics | Transcription Factors - genetics | DNA-Binding Proteins - genetics | Mutation - genetics | Nerve Tissue Proteins - genetics | Sequence Analysis, DNA | Homeodomain Proteins - genetics | DEAD-box RNA Helicases - genetics | Exome - genetics | Phenotype | Myeloid-Lymphoid Leukemia Protein - genetics | Adolescent | Heredity - genetics | Protein Phosphatase 2C - genetics | Cohort Studies | Child development deviations | Genetic aspects | Genetic disorders | Developmental disabilities | Distribution | Genes | Families & family life | Births | Genomes | Mutation | Causality | Estimates | Age | Index Medicus | TRIO | MYT1L | EHMT1 | HNRNPU | SUV420H1 | COL4A3BP | SYNGAP1 | PPP2R1A | POGZ | EP300 | KCNH1 | SCN1A | MEF2C | CDKL5 | CSNK2A1 | DYRK1A | CASK | ALG13 | FOXP1 | KAT6B | TBL1XR1 | KAT6A | SCN8A | KCNQ2 | EEF1A2 | KCNQ3 | ADNP | PhenIcons | SET | KMT2A | ANKRD11 | STXBP1 | FOXG1 | ZC4H2 | ITPR1 | De novo mutation | Seizures | ZBTB18 | CREBBP | SMAD4 | PDHA1 | IQSEC2 | AUTS2 | BCL11A | BRAF | SMARCA2 | GRIN2B | MED13L | GNAO1 | CNOT3 | TCF4 | SCN2A | CDK13 | GABRB3 | SETD5 | KDM5B | Developmental Disease | DDX3X | CHD8 | PTEN | CHD4 | TCF20 | CTCF | CHD2 | WDR45 | SLC6A1 | MECP2 | CHAMP1 | KIF1A | Average Faces | MSL3 | PPP2R5D | SMC1A | ARID1B | DNM1 | CNKSR2 | PACS1 | WAC | ZMYND11 | AHDC1 | NFIX | SATB2 | HDAC8 | PPM1D | GNAI1 | PURA | PUF60 | NSD1 | Intellectual Disability | SLC35A2 | DYNC1H1 | NAA10 | USP9X | PTPN11 | GATAD2B | ASXL1 | KANSL1 | ASXL3 | CTNNB1 | QRICH1
Journal Article