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Journal of Clinical Oncology, ISSN 0732-183X, 12/2013, Volume 31, Issue 34, pp. 4333 - 4342
Purpose The Group for Research in Adult Acute Lymphoblastic Leukemia (GRAALL) recently reported a significantly better outcome in T-cell acute lymphoblastic... 
REGRESSION | ACTIVATION | THERAPY | NOTCH1 | PRETHYMIC PHENOTYPE | ONCOLOGY | PATHWAY | GENES | PTEN | MUTATIONS | EXPRESSION | F-Box-WD Repeat-Containing Protein 7 | Multivariate Analysis | Predictive Value of Tests | ras Proteins - genetics | Proto-Oncogene Proteins p21(ras) | Humans | Male | Precursor T-Cell Lymphoblastic Leukemia-Lymphoma - mortality | Young Adult | Time Factors | DNA Mutational Analysis | Gene Deletion | Cell Cycle Proteins - genetics | Adult | Female | Precursor T-Cell Lymphoblastic Leukemia-Lymphoma - therapy | PTEN Phosphohydrolase - genetics | Genetic Predisposition to Disease | Membrane Proteins - genetics | Risk Factors | Kaplan-Meier Estimate | Proportional Hazards Models | Proto-Oncogene Proteins - genetics | Disease-Free Survival | Phenotype | GTP Phosphohydrolases - genetics | Precursor T-Cell Lymphoblastic Leukemia-Lymphoma - genetics | Precursor T-Cell Lymphoblastic Leukemia-Lymphoma - classification | Mutation | Receptor, Notch1 - genetics | Ubiquitin-Protein Ligases - genetics | F-Box Proteins - genetics | Index Medicus | GTP Phosphohydrolases | ras Proteins | Innate immunity | Life Sciences | F-Box Proteins | Immunology | PTEN Phosphohydrolase | Proto-Oncogene Proteins | Membrane Proteins | Ubiquitin-Protein Ligases | Precursor T-Cell Lymphoblastic Leukemia-Lymphoma | Receptor, Notch1 | Cell Cycle Proteins
Journal Article
2016, Methods in molecular biology, ISBN 9781493932979, Volume 1388
This volume provides detailed descriptions of prevailing and novel techniques used by experts in the study of PTEN function in disease and biology. 
PTEN Phosphohydrolase | Tumor Suppressor Proteins
Web Resource
Science, ISSN 0036-8075, 7/2013, Volume 341, Issue 6144, pp. 399 - 402
Journal Article
Nature, ISSN 0028-0836, 02/2015, Volume 518, Issue 7538, pp. 240 - 244
Journal Article
PLoS Biology, ISSN 1544-9173, 06/2009, Volume 7, Issue 6, pp. e1000121 - e1000121
Journal Article
Cell Metabolism, ISSN 1550-4131, 03/2014, Volume 19, Issue 3, pp. 393 - 406
Journal Article
Science, ISSN 0036-8075, 9/2009, Volume 325, Issue 5945, pp. 1261 - 1265
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 3/2010, Volume 107, Issue 12, pp. 5471 - 5476
The phosphatidylinositol 3-kinase (PI3K) signaling pathway is deregulated in many human diseases including cancer, diabetes, obesity, and autoimmunity. PI3K... 
Proteins | Phosphatases | HeLa cells | Lipids | Insulin resistance | Gene expression regulation | Physiological regulation | Insulin | Phosphatidylinositols | Cancer | Explains mouse phenotypes | Lipid phosphatase | Protein:protein interactions | PTEN tumor suppressor | Insulin signaling | CATALYTIC SUBUNIT | MULTIDISCIPLINARY SCIENCES | P85-ALPHA SUBUNIT | PHOSPHOINOSITIDE 3-KINASE | CANCER | MICE LACKING | 3'-KINASE | insulin signaling | GENE | PI3K | NEOPLASIA | lipid phosphatase | protein:protein interactions | explains mouse phenotypes | INCREASED INSULIN SENSITIVITY | Protein Subunits | Sequence Deletion | Humans | Cercopithecus aethiops | Phosphatidylinositol 3-Kinases - metabolism | Recombinant Fusion Proteins - metabolism | Phosphatidylinositol 3-Kinases - deficiency | Protein Interaction Domains and Motifs | Peptide Fragments - genetics | PTEN Phosphohydrolase - genetics | PTEN Phosphohydrolase - deficiency | Peptide Fragments - metabolism | Signal Transduction | Phosphatidylinositol 3-Kinases - chemistry | PTEN Phosphohydrolase - metabolism | Epidermal Growth Factor - metabolism | Recombinant Fusion Proteins - chemistry | Mice, Knockout | Phosphatidylinositol 3-Kinases - genetics | Insulin - metabolism | Peptide Fragments - chemistry | Phenotype | Animals | Protein Binding | Recombinant Fusion Proteins - genetics | Mice | HeLa Cells | COS Cells | PTEN Phosphohydrolase - chemistry | Phosphatidylinositol | Chemical properties | Research | Phosphotransferases | Protein-protein interactions | Tumors | Signal transduction | Cell growth | Enzyme kinetics | Kinases | Gene expression | Binding sites | Index Medicus | Biological Sciences
Journal Article
Nature, ISSN 0028-0836, 11/2014, Volume 515, Issue 7525, pp. 134 - 137
Journal Article
Nature Neuroscience, ISSN 1097-6256, 09/2010, Volume 13, Issue 9, pp. 1075 - 1081
Journal Article
Cellular Physiology and Biochemistry, ISSN 1015-8987, 06/2015, Volume 36, Issue 3, pp. 956 - 965
Background: Berberine, a well-known component of the Chinese herbal medicine Huanglian, has wide range of biochemical and pharmacological effects, including... 
Original Paper | Berberine | miR-93 | Ovarian cancer cells | Cisplatin | APOPTOSIS | PHYSIOLOGY | INVOLVEMENT | CYCLE ARREST | MICRORNAS | mir-93 | CHEMOTHERAPY | CELL BIOLOGY | LEUKEMIA-CELLS | RESISTANCE | CHEMORESISTANCE | CARCINOMA | EXPRESSION | RNA, Small Interfering - genetics | Epithelial Cells - metabolism | Luciferases - metabolism | MicroRNAs - antagonists & inhibitors | Apoptosis - drug effects | Epithelial Cells - drug effects | Humans | Gene Expression Regulation, Neoplastic | MicroRNAs - metabolism | Proto-Oncogene Proteins c-akt - genetics | Luciferases - genetics | PTEN Phosphohydrolase - antagonists & inhibitors | Ribonucleosides - pharmacology | Female | Ovary - drug effects | Antineoplastic Agents - pharmacology | Proto-Oncogene Proteins c-akt - metabolism | Genes, Reporter | Ovary - metabolism | PTEN Phosphohydrolase - agonists | PTEN Phosphohydrolase - genetics | Ovary - pathology | Signal Transduction | PTEN Phosphohydrolase - metabolism | Epithelial Cells - pathology | Cisplatin - pharmacology | Drug Synergism | Berberine - pharmacology | Drug Resistance, Neoplasm - genetics | Cell Line, Tumor | MicroRNAs - genetics | G1 Phase Cell Cycle Checkpoints - drug effects | Proto-Oncogene Proteins c-akt - antagonists & inhibitors | Drug Resistance, Neoplasm - drug effects | RNA, Small Interfering - metabolism | Index Medicus
Journal Article