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Journal of clinical oncology, ISSN 1527-7755, 2013, Volume 31, Issue 34, pp. 4333 - 4342
Journal Article
PLoS biology, ISSN 1545-7885, 2009, Volume 7, Issue 6, p. e1000121
Journal Article
Journal Article
Proceedings of the National Academy of Sciences - PNAS, ISSN 1091-6490, 2013, Volume 110, Issue 10, pp. 4039 - 4044
Journal Article
Leukemia, ISSN 0887-6924, 07/2011, Volume 25, Issue 7, pp. 1064 - 1079
... of genetic alterations in critical components in this pathway as well as mutations at upstream growth factor receptors... 
mTOR | translation | sensitivity | PI3K | therapy | resistance | TUMOR-SUPPRESSOR CANDIDATE | PROTEIN-KINASE | INITIATION-FACTOR 4E | ACUTE MYELOID-LEUKEMIA | GROWTH-FACTOR RECEPTOR | BONE-MARROW MICROENVIRONMENT | ONCOLOGY | AKT/PROTEIN-KINASE-B | ACUTE LYMPHOBLASTIC-LEUKEMIA | HEMATOPOIETIC STEM-CELLS | CHRONIC LYMPHOCYTIC-LEUKEMIA | HEMATOLOGY | Apoptosis - drug effects | Neoplastic Stem Cells - drug effects | Humans | Neoplasm Proteins - physiology | PTEN Phosphohydrolase - physiology | Apoptosis - genetics | Neoplasm Proteins - antagonists & inhibitors | Antineoplastic Agents - therapeutic use | Molecular Targeted Therapy | Phosphatidylinositol 3-Kinases - antagonists & inhibitors | Proto-Oncogene Proteins c-akt - genetics | Gene Expression Regulation, Leukemic - genetics | Mechanistic Target of Rapamycin Complex 1 | Multiprotein Complexes - antagonists & inhibitors | Transcription Factors - drug effects | TOR Serine-Threonine Kinases - antagonists & inhibitors | PTEN Phosphohydrolase - antagonists & inhibitors | TOR Serine-Threonine Kinases - genetics | Protein Processing, Post-Translational - drug effects | Drug Design | TOR Serine-Threonine Kinases - physiology | Antineoplastic Agents - pharmacology | Phosphorylation - drug effects | Neoplasm Proteins - genetics | Leukemia - genetics | Multiprotein Complexes - drug effects | PTEN Phosphohydrolase - genetics | Proteins - physiology | Transcription Factors - physiology | RNA, Messenger - genetics | Gene Expression Regulation, Leukemic - drug effects | Leukemia - drug therapy | Transcription Factors - antagonists & inhibitors | Proto-Oncogene Proteins c-akt - physiology | Multiprotein Complexes - physiology | Phosphatidylinositol 3-Kinases - genetics | Drug Resistance, Neoplasm - genetics | Pseudogenes | Signal Transduction - drug effects | Phosphatidylinositol 3-Kinases - physiology | Proteins - drug effects | RNA, Neoplasm - genetics | Protein Biosynthesis - drug effects | MicroRNAs - genetics | Proteins - antagonists & inhibitors | Proto-Oncogene Proteins c-akt - antagonists & inhibitors | Drug Resistance, Neoplasm - drug effects | Antimitotic agents | Genes | Leukemia | Physiological aspects | Development and progression | Genetic aspects | Research | Antineoplastic agents | Drug therapy | Health aspects
Journal Article
Journal Article
Cellular physiology and biochemistry, ISSN 1421-9778, 2015, Volume 36, Issue 3, pp. 956 - 965
Background: Berberine, a well-known component of the Chinese herbal medicine Huanglian, has wide range of biochemical and pharmacological effects, including... 
Original Paper | Berberine | miR-93 | Ovarian cancer cells | Cisplatin | APOPTOSIS | PHYSIOLOGY | INVOLVEMENT | CYCLE ARREST | MICRORNAS | mir-93 | CHEMOTHERAPY | CELL BIOLOGY | LEUKEMIA-CELLS | RESISTANCE | CHEMORESISTANCE | CARCINOMA | EXPRESSION | RNA, Small Interfering - genetics | Epithelial Cells - metabolism | Luciferases - metabolism | MicroRNAs - antagonists & inhibitors | Apoptosis - drug effects | Epithelial Cells - drug effects | Humans | Gene Expression Regulation, Neoplastic | MicroRNAs - metabolism | Proto-Oncogene Proteins c-akt - genetics | Luciferases - genetics | PTEN Phosphohydrolase - antagonists & inhibitors | Ribonucleosides - pharmacology | Female | Ovary - drug effects | Antineoplastic Agents - pharmacology | Proto-Oncogene Proteins c-akt - metabolism | Genes, Reporter | Ovary - metabolism | PTEN Phosphohydrolase - agonists | PTEN Phosphohydrolase - genetics | Ovary - pathology | Signal Transduction | PTEN Phosphohydrolase - metabolism | Epithelial Cells - pathology | Cisplatin - pharmacology | Drug Synergism | Berberine - pharmacology | Drug Resistance, Neoplasm - genetics | Cell Line, Tumor | MicroRNAs - genetics | G1 Phase Cell Cycle Checkpoints - drug effects | Proto-Oncogene Proteins c-akt - antagonists & inhibitors | Drug Resistance, Neoplasm - drug effects | RNA, Small Interfering - metabolism
Journal Article