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humans (774) 774
index medicus (705) 705
pten (601) 601
animals (512) 512
pten phosphohydrolase - metabolism (440) 440
pten phosphohydrolase - genetics (375) 375
oncology (321) 321
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phosphorylation (264) 264
biochemistry & molecular biology (252) 252
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proto-oncogene proteins c-akt - metabolism (231) 231
cell biology (211) 211
phosphatase (207) 207
cell line, tumor (199) 199
akt (194) 194
phosphatidylinositol 3-kinases - metabolism (186) 186
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gene expression regulation, neoplastic (92) 92
akt protein (88) 88
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multidisciplinary sciences (86) 86
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pi3k (80) 80
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phosphoric monoester hydrolases - genetics (78) 78
rats (78) 78
genetics & heredity (77) 77
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phosphoric monoester hydrolases - metabolism (75) 75
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ACS Chemical Biology, ISSN 1554-8929, 11/2006, Volume 1, Issue 12, pp. 780 - 790
Journal Article
Nature Cell Biology, ISSN 1465-7392, 06/2011, Volume 13, Issue 6, pp. 730 - 735
Journal Article
Journal Article
Circulation, ISSN 0009-7322, 10/2007, Volume 116, Issue 14, pp. 1585 - 1595
Background - Oxidative stress plays a causal role in vascular injury in diabetes mellitus, but the mechanisms and targets remain poorly understood. Methods and... 
Endothelium-derived factors | Hyperglycemia | Peroxynitrite | Apoptosis | Endothelium | endothelium | AORTIC ENDOTHELIAL-CELLS | CARDIAC & CARDIOVASCULAR SYSTEMS | peroxynitrite | ACTIVATED PROTEIN-KINASE | PHOSPHORYLATION | NITRIC-OXIDE SYNTHASE | apoptosis | endothelium-derived factors | hyperglycemia | HIGH GLUCOSE | TUMOR-SUPPRESSOR | INSULIN HYPERSENSITIVITY | PERIPHERAL VASCULAR DISEASE | HEMATOLOGY | TYROSINE NITRATION | EXPRESSION | Diabetes Mellitus, Experimental - drug therapy | Phosphorylation | Humans | Male | Endothelium, Vascular - enzymology | Threonine - metabolism | Hyperglycemia - drug therapy | Up-Regulation - physiology | Hyperglycemia - pathology | Diabetes Mellitus, Experimental - metabolism | Proto-Oncogene Proteins c-akt - metabolism | Umbilical Veins - cytology | Protein-Serine-Threonine Kinases - metabolism | Insulin - pharmacology | Reactive Nitrogen Species - metabolism | Cells, Cultured | PTEN Phosphohydrolase - metabolism | Serine - metabolism | Hypoglycemic Agents - pharmacology | Hyperglycemia - metabolism | Animals | Signal Transduction - drug effects | Peroxynitrous Acid - metabolism | Diabetes Mellitus, Experimental - pathology | Endothelium, Vascular - pathology | Signal Transduction - physiology | Mice | Apoptosis - physiology | Oxidative stress | Blood circulation disorders | Diabetics | Blood sugar | Physiological aspects | Research | Health aspects | Protein kinases | Risk factors
Journal Article
Journal Article
BMC Cancer, ISSN 1471-2407, 08/2008, Volume 8, Issue 1, pp. 234 - 234
Journal Article
BMC Medical Genomics, ISSN 1755-8794, 11/2017, Volume 10, Issue 1, pp. 64 - 8
Background: MiRNAs are frequently abnormally expressed in the progression of human osteosarcoma. Phosphatase and tensin homologue deleted on chromosome 10... 
MiR-30a | PTEN | Anti-tumor | Osteosarcoma | MIRNA | GENETICS & HEREDITY | TUMOR-GROWTH | CARCINOMA | Genetic aspects | MicroRNA | Research | Gene expression
Journal Article
British Journal of Pharmacology, ISSN 0007-1188, 12/2007, Volume 152, Issue 8, pp. 1172 - 1184
Journal Article
摘要 PTEN (phosphatase and Tensin homolog deleted on chromosome 10,亦稱MMAC1 or TEP1)為一種磷酸酶,擷抗磷脂酰肌醇激酶(PI3K;phosphoinositide 3-kinase)所引起的生理活性。內皮分化因子(Endothlial... 
鹼性纖維母細胞 | endothelial cells | 生長因子補充劑 | gas glands | insulin | 類胰島素生長因子 | EDF-1 | PTEN | IGF-1 | bFGF | 過氧化體增殖劑活化受器 | PI3K | PPAR | 睪固酮 | 胰島素增敏劑 | steroids | 卵巢發育指數 | GSI | 紅體發育指數
Dissertation
The FEBS Journal, ISSN 1742-464X, 01/2014, Volume 281, Issue 1, pp. 88 - 103
Phosphatase and tensin homologue deleted on chromosome 10 (PTEN) has been reported to play a role in the suppression of activated hepatic stellate cells... 
DNA methylation | microRNA‐29b | DNA methyltransferase | hepatic stellate cells | phosphatase and tensin homologue deleted on chromosome 10 | microRNA-29b | ACTIVATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | RECEPTOR | IN-VITRO | INHIBITION | METHYLTRANSFERASES | GROWTH | TUMORIGENESIS | EXPRESSION | PROGRESSION | RNA, Small Interfering - genetics | Luciferases - metabolism | Apoptosis - drug effects | Humans | Male | DNA (Cytosine-5-)-Methyltransferases - antagonists & inhibitors | Liver Cirrhosis - chemically induced | Proto-Oncogene Proteins c-akt - genetics | DNA (Cytosine-5-)-Methyltransferases - metabolism | PTEN Phosphohydrolase - antagonists & inhibitors | Antineoplastic Agents - pharmacology | Proto-Oncogene Proteins c-akt - metabolism | Liver Cirrhosis - genetics | Real-Time Polymerase Chain Reaction | Hepatic Stellate Cells - pathology | Hepatic Stellate Cells - drug effects | Chromosome Deletion | PTEN Phosphohydrolase - genetics | Promoter Regions, Genetic | Liver Cirrhosis - prevention & control | RNA, Messenger - genetics | Cells, Cultured | Curcumin - pharmacology | Gene Expression Regulation | PTEN Phosphohydrolase - metabolism | Rats | Carbon Tetrachloride - toxicity | Reverse Transcriptase Polymerase Chain Reaction | Rats, Sprague-Dawley | Blotting, Western | DNA (Cytosine-5-)-Methyltransferases - genetics | Animals | Cell Proliferation - drug effects | MicroRNAs - genetics | Chromosomes, Human, Pair 10 - genetics | DNA Methylation - drug effects | Liver diseases | Phosphatases | MicroRNA | Liver | DNA | Fibrosis | Genetic research | Genetic transcription | Methylation | Epigenetics | MicroRNAs | Apoptosis
Journal Article
Journal Article
2007
PTEN is a tumour suppressor protein named after its homology with phosphatase and tensin and its frequent deletion on chromosome 10. PTEN was discovered to be... 
Dissertation