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The Journal of biological chemistry, ISSN 0021-9258, 04/2015, Volume 290, Issue 16, pp. 10325 - 10335
Life Sciences & Biomedicine | Biochemistry & Molecular Biology | Science & Technology | Electron Transport | Protein Kinases - genetics | Dopaminergic Neurons - pathology | Humans | Mitochondrial Degradation - genetics | Dopaminergic Neurons - metabolism | HEK293 Cells | Parkinson Disease - metabolism | Protein Kinases - deficiency | Disease Models, Animal | Fibroblasts - metabolism | Nitric Oxide - biosynthesis | Parkinson Disease - pathology | Signal Transduction | Mice, Inbred C57BL | Gene Expression Regulation | Ubiquitin-Protein Ligases - metabolism | Mitochondria - metabolism | Parkinson Disease - genetics | Fibroblasts - pathology | Mice, Knockout | Nitric Oxide Synthase Type I - deficiency | Protein Transport | Animals | Protein Binding | Mice | Nitric Oxide Synthase Type I - genetics | Primary Cell Culture | Ubiquitin-Protein Ligases - genetics | Index Medicus | Parkinson Disease | Molecular Bases of Disease | nNOS | Nitric Oxide | Mitophagy | PTEN-induced Putative Kinase 1 (PINK1) | Parkin
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The Journal of biological chemistry, ISSN 0021-9258, 07/2015, Volume 290, Issue 27, pp. 16882 - 16893
Life Sciences & Biomedicine | Biochemistry & Molecular Biology | Science & Technology | Protein Kinases - metabolism | Mitochondria - enzymology | Protein Kinases - genetics | Humans | Mice, Inbred C57BL | Protein Kinases - chemistry | NF-kappa B - metabolism | Mitochondria - metabolism | Amino Acid Motifs | Mitochondrial Degradation | Cytosol - enzymology | Ubiquitination | Animals | Mitochondria - genetics | NF-kappa B - genetics | Neurons - enzymology | TNF Receptor-Associated Factor 6 - metabolism | Cytosol - metabolism | Mice | Neurons - metabolism | Protein Stability | TNF Receptor-Associated Factor 6 - genetics | Index Medicus | Parkinson disease | ubiquitylation (ubiquitination) | mitophagy | PTEN-induced putative kinase 1 (PINK1) | parkin | Cell Biology
Journal Article
Journal of the American College of Cardiology, ISSN 0735-1097, 10/2018, Volume 72, Issue 16, pp. C14 - C14
Journal Article
Biochemical and biophysical research communications, ISSN 0006-291X, 08/2016, Volume 476, Issue 4, pp. 299 - 305
β-cells | Autophagy | Phosphatase and tensin homologue (PTEN)-induced putative kinase 1 | Apoptosis | High glucose | Biochemistry & Molecular Biology | Biophysics | Life Sciences & Biomedicine | Science & Technology | Protein Kinases - metabolism | RNA, Small Interfering - genetics | Protein Kinases - genetics | Rats, Wistar | PTEN Phosphohydrolase - metabolism | Male | Insulin-Secreting Cells - metabolism | Animals | RNA Interference | Glucose - metabolism | Insulin-Secreting Cells - cytology | Index Medicus
Journal Article
Journal of diabetes investigation, ISSN 2040-1116, 05/2015, Volume 6, Issue 3, pp. 250 - 255
Heart | Phosphatase and tensin homolog‐induced putative kinase 1/Parkin | Diabetes | Phosphatase and tensin homolog-induced putative kinase 1/Parkin | Life Sciences & Biomedicine | Endocrinology & Metabolism | Science & Technology | Phosphatases | Tensin | Parkinson's disease | Neurodegenerative diseases | Diabetes mellitus | Cardiomyocytes | Mitochondrial DNA | Kinases | Morbidity | Risk factors | Mitochondria | PTEN-induced putative kinase | Myocardium | Parkin protein | Cardiovascular diseases | ATP | PTEN protein | Movement disorders | Adenosine triphosphate | Apoptosis | Phosphatase and tensin homolog-induced putative kinase 1 | Mini Review | Parkin
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Journal of international medical research, ISSN 0300-0605, 5/2020, Volume 48, Issue 5, pp. 300060519896143 - 300060519896143
Journal Article
FEBS letters, ISSN 0014-5793, 12/2015, Volume 589, Issue 24, pp. 3760 - 3772
Rearranged during transfection | Parkinson disease | Drug addiction | Mouse model | Dopaminergic system | Glia cell line-derived neurotrophic factor | MAOA/MAOB | orphan nuclear receptor and transcription factor | cytoplasmic SH2 domain containing protein tyrosine phosphatase | Ras | RRF | COMT | PTEN-induced putative kinase 1 | SH3 and multiple ankyrin repeat domains 3, proline-rich synapse-associated protein 2 (ProSAP2) | PI3K | sorting protein-related receptor with A-type repeats, a member of the mammal Vps10p domain receptor | subunits of the Ca2+-sensitive, voltage gated A-type K+ channel | SH2 domain containing transforming protein 1 | Nurr1 | proprotein convertases | protein kinase B, serine/threonine-specific protein kinase | calcium-calmodulin-dependent protein kinase II β isoform | FRS2 | phosphatase and tensin homolog | catecholamine | SHP-2 | growth factor receptor-bound protein 2, 7 and 10, adaptor proteins | fibroblast growth factor receptor substrate 2, adaptor protein | monoamine oxidases A and B | carbonyl cyanide m-chlorophenyl hydrazone | ERK | brain derived neurotrophic factor | deglycase, oxidative stress sensor and redox-sensitive chaperone and protease | VTA | tyrosines, which can be phosphorylated | cAMP | extracellular-signal-regulated kinases, classical MAPKs | CaMKIIβ | Kv4.3 and KChip3 | GRB2/7/10 | Ser/Thr | SNP | endoplasmatic reticulum | nerve growth factor | monoamine, neurotransmitter type including dopamine, epinephrine (adrenaline) and norepinephrine (noradrenaline) | TGF-β | SN | Akt, PKB | phospholipase γ cleaves the phospholipid phosphatidylinositol 4,5-bisphosphate (PIP2) into diacyl glycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) ppp3R1/ppp3CB, calcineurin subunits | PC5A, PC5B, and PC7 | EGR1 | proprotein convertase subtilisin/kexin type 6 | substantia nigra | phosphotyrosine-interaction domain | BDNF | adaptor protein of the PDZ-LIM family | γ-aminobutyric acid, inhibitory neurotransmitter in mammalian central nervous system | Tyr | FosB/ΔFosB | IRS1/2 | LIM | dopamine transporter | enhanced green fluorescent protein | GDNF | DAT | SOS | 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine | retro-rubal field | transforming growth factor β is a secreted protein that controls proliferation and cellular differentiation | MPTP | GTPase | DA | hypoxia-inducible factor-1alpha | GDNF family of ligands | Ret | GPI | Shank3 | NCAM | Enigma | JNK | (rearranged during transfection) canonical GDNF receptor, a receptor tyrosine kinase | PTEN | 6-OHDA | DJ-1 | (rapidly accelerated fibrosarcoma/rat fibrosarcoma) family of serine/threonine-protein kinase | SHC | NF-κB | (acronym combining the first letters of three proteins – post synaptic density protein (PSD95), Drosophila disc large tumor suppressor (Dlg1), and zonula occludens-1 protein (zo-1) that have this common domain) protein interaction domain | phosphotyrosine-binding domains | insulin receptor substrate 1, adaptor protein, contains a PTB and PH domain | Rac1 | GFRα | nuclear factor ‘kappa-light-chain-enhancer’ of activated B-cells, transcription factor family with Rel homology domain (RHD) | catechol-O-methyltransferase | early growth response protein 1, Zif268 (zinc finger protein 225), NGFI-A (nerve growth factor-induced protein A), is a zinc finger transcription factor | serine and threonine, which can be phosphorylated | GDNF family receptor α | PKA | protein kinase A, a family of cAMP-dependent protein kinase | MAPK | NGF | ER | SorLA | ventral tegmental area | son of sevenless, family of guanine nucleotide exchange factors that act on Ras | GABA | HIF-1a | Ras-related C3 botulinum toxin substrate 1 (Rho family), a small GTPase, like CDC42 | GAP1/2 | PTB | (Rat sarcoma) family of small membrane-associated GTPase | cycles between an active GTP-bound and an inactive GDP-bound state | glycogen synthase kinase 3β | Src | glia cell line-derived neurotrophic factor | PACE4, PCSK6 | pleckstrin homology domain | co-repressor for element-1-silencing transcription factor, a chromatin-modifying corepressor complex that acts with REST (repressor for element-1 silencing transcription factor) complex | c-Jun N-terminal kinases, members of the MAPK family of proteins | EGFP | cell division control protein 42 homolog, a plasma membrane-associated small GTPase of the Rho family | (acronym combining the first letters of three proteins – Lin11, Isl-1 and Mec-3 – that have this common domain) protein interaction domain of two contiguous zinc finger domains, separated by a two-amino acid residue hydrophobic linker | CCCP | (sarcoma protein) membrane-associated tyrosine kinase with different Src homology (SH) domains characteristic for all 9 members of the Src family kinases | DOK1/4/5/6 | (Ras homolog) family of small GTPases including Cdc42, Rac1, and RhoA | single-nucleotide polymorphism analysis | VPS10P | Rho | MEN2B | phosphatidylinositol-4,5-bisphosphate 3-kinase | 6-hydroxy-dopamine | mitogen-activated protein kinase, can phosphorylate serine, threonine, and tyrosine, e.g. p38MAPK | Cdc42 | docking proteins, have a PH and SH3 domain | GFLs | PDZ | vacuolar protein sorting 10 protein-domain receptors are type 1 transmembrane proteins | PLCγ | GTPase-activating proteins 1 and 2 | 3′,5′-cyclic adenosine monophosphate | neuronal cell adhesion molecule | TIEG | TGF-β-inducible early-response gene, a zinc finger transcription factor Vav2, adaptor protein and guanine nucleotide exchange factor for the Rho family of Ras-related GTPases | PINK1 | PD | Raf | CoREST | PH | PI | multiple endocrine neoplasia 2 type B, mutation in the kinase domain of the Ret leading to constitutive active receptor | dopaminergic | glycosylphosphatidylinositol | FBJ murine osteosarcoma viral oncogene homolog B, a transcription factor with a truncated Δ form | gsk3β | Biochemistry & Molecular Biology | Biophysics | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Glial Cell Line-Derived Neurotrophic Factor - physiology | Parkinson Disease - pathology | Animals | Proto-Oncogene Proteins c-ret - physiology | Dopamine - physiology | Mesencephalon - metabolism | Humans | Dopaminergic Neurons - physiology | Parkinson Disease - metabolism | Synaptic Transmission | Mesencephalon - pathology | Physiological aspects | Neurons | Parkinson's disease | Index Medicus
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