X
Search Filters
Format Format
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
index medicus (1197) 1197
animals (824) 824
pu.1 (733) 733
humans (682) 682
mice (636) 636
transcription factor pu.1 (396) 396
biochemistry & molecular biology (376) 376
differentiation (372) 372
proto-oncogene proteins - metabolism (357) 357
trans-activators - metabolism (349) 349
expression (346) 346
cell biology (324) 324
proto-oncogene proteins - genetics (323) 323
immunology (320) 320
transcription factors (316) 316
trans-activators - genetics (308) 308
gene expression (285) 285
hematology (283) 283
cell differentiation (277) 277
pu.1 protein (251) 251
oncology (203) 203
gene-expression (201) 201
molecular sequence data (199) 199
leukemia (196) 196
base sequence (190) 190
transcription factors - metabolism (189) 189
hematopoiesis (185) 185
gene expression regulation (183) 183
gene (182) 182
cell line (174) 174
promoter regions, genetic (172) 172
transcription factor (171) 171
cells, cultured (166) 166
abridged index medicus (158) 158
transcription factors - genetics (157) 157
article (153) 153
cells (153) 153
binding sites (152) 152
protein binding (152) 152
proteins (151) 151
transcription, genetic (145) 145
macrophages (140) 140
colony-stimulating factor (139) 139
activation (138) 138
genes (136) 136
dna-binding proteins - metabolism (135) 135
dna-binding proteins - genetics (134) 134
acute myeloid-leukemia (132) 132
analysis (132) 132
research (132) 132
genetics & heredity (131) 131
signal transduction (128) 128
mice, inbred c57bl (125) 125
female (120) 120
genetic aspects (118) 118
multidisciplinary sciences (115) 115
proto-oncogene proteins - physiology (114) 114
trans-activators - physiology (113) 113
cell differentiation - genetics (112) 112
transcription (111) 111
stem cells (110) 110
mice, knockout (109) 109
male (108) 108
mutation (106) 106
in-vivo (101) 101
stem-cells (101) 101
factor pu.1 (100) 100
hematopoietic stem-cells (100) 100
dendritic cells (99) 99
macrophage (97) 97
cancer (96) 96
cell lineage (95) 95
cell line, tumor (94) 94
transfection (94) 94
transcriptional activation (93) 93
chromatin (90) 90
dna-binding (90) 90
hematopoietic stem cells - cytology (89) 89
research article (88) 88
macrophages - metabolism (85) 85
promoter (85) 85
protein (84) 84
amino acid sequence (83) 83
apoptosis (82) 82
lineage commitment (81) 81
nf-kappa-b (80) 80
inflammation (79) 79
physiological aspects (78) 78
dna binding proteins (77) 77
hematopoietic stem cells - metabolism (77) 77
hemic and lymphatic diseases (76) 76
transcription factors - physiology (76) 76
dna (74) 74
dna - metabolism (74) 74
promoter regions, genetic - genetics (74) 74
rodents (73) 73
lymphocytes (72) 72
medicine, research & experimental (72) 72
reverse transcriptase polymerase chain reaction (72) 72
cytokines (71) 71
more...
Language Language
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 9/2011, Volume 108, Issue 36, pp. 14902 - 14907
Epstein-Barr virus nuclear antigen 2 (EBNA2) regulation of transcription through the cell transcription factor RBPJ is essential for resting B-lymphocyte (RBL)... 
T lymphocytes | Up regulation | Chromatin | B lymphocytes | DNA | Nucleosomes | Gene expression regulation | Epstein Barr virus infections | Human herpesvirus 4 | Binding sites | Development | Lymphoma | Leukemia | Notch | leukemia | development | SIGNAL-BINDING-PROTEIN | CIS-ELEMENT | MULTIDISCIPLINARY SCIENCES | lymphoma | C-MYC | NUCLEAR ANTIGEN-2 | FATE | GENOME | LONG-RANGE INTERACTION | GENE | PROMOTER | J-KAPPA | Cell Proliferation | Herpesvirus 4, Human - genetics | Proto-Oncogene Proteins c-ets - genetics | Genome, Viral - genetics | Humans | Transcription Factor RelA - genetics | Viral Proteins - metabolism | Trans-Activators - genetics | B-Lymphocytes - virology | Epstein-Barr Virus Infections - genetics | Core Binding Factor alpha Subunits - metabolism | Transcription, Genetic | Proto-Oncogene Proteins c-ets - metabolism | Epstein-Barr Virus Nuclear Antigens - metabolism | Immunoglobulin J Recombination Signal Sequence-Binding Protein - genetics | B-Lymphocytes - metabolism | Proto-Oncogene Proteins - metabolism | Immunoglobulin J Recombination Signal Sequence-Binding Protein - metabolism | Epstein-Barr Virus Nuclear Antigens - genetics | Response Elements | Nucleosomes - metabolism | Viral Proteins - genetics | Nucleosomes - genetics | Proto-Oncogene Proteins - genetics | Proto-Oncogene Proteins c-myc - metabolism | Core Binding Factor alpha Subunits - genetics | Transcription Factor RelA - metabolism | Cell Line, Tumor | Trans-Activators - metabolism | Proto-Oncogene Proteins c-myc - genetics | Herpesvirus 4, Human - metabolism | Epstein-Barr Virus Infections - metabolism | Physiological aspects | Transcription factors | Epstein-Barr virus | Genetic aspects | Lymphocytes | Health aspects | Cell growth | Deoxyribonucleic acid--DNA | Index Medicus | ETS protein | Lymphoblasts | Introns | Data processing | Genomes | Myc protein | Promoters | Early B-cell factor | Infection | Enhancers | PU.1 protein | Lymphocytes B | Fluorescence in situ hybridization | RelA protein | Conformation | Biological Sciences
Journal Article
PLoS ONE, ISSN 1932-6203, 05/2015, Volume 10, Issue 5, pp. e0126385 - e0126385
The murine Cebpa gene contains an evolutionarily conserved 453 bp enhancer located at +37 kb that, together with its promoter, directs expression to myeloid... 
CELLS | INHIBITION | MULTIDISCIPLINARY SCIENCES | GRANULOCYTIC DIFFERENTIATION | C-MYB | LEUKEMIA | PROMOTER | TRANSCRIPTION FACTOR | CCAAT-Enhancer-Binding Proteins - metabolism | Proto-Oncogene Proteins - metabolism | Cell Line | CCAAT-Enhancer-Binding Protein-alpha - metabolism | Core Binding Factor Alpha 2 Subunit - metabolism | Proto-Oncogene Proteins c-ets - genetics | Humans | Proto-Oncogene Proteins - genetics | Regulatory Sequences, Nucleic Acid - genetics | Point Mutation - genetics | Animals | GATA2 Transcription Factor - metabolism | Trans-Activators - genetics | CCAAT-Enhancer-Binding Protein-alpha - genetics | Protein Binding | Trans-Activators - metabolism | Enhancer Elements, Genetic - genetics | Mice | Proto-Oncogene Proteins c-ets - metabolism | CCAAT-Enhancer-Binding Proteins - genetics | Core Binding Factor Alpha 2 Subunit - genetics | GATA2 Transcription Factor - genetics | Pediatrics | Transformation | Transcription factors | Ets-1 protein | Transcription | Leukemia | Stem cell transplantation | Oncology | Genomes | CCAAT/enhancer-binding protein | CEBPA gene | FLI-1 protein | Hematopoietic stem cells | PU.1 protein | Allografts | Granulocytes | Granulocyte colony-stimulating factor | Interleukin 3 | Hematopoiesis | Rodents | c-Myb protein | Deoxyribonucleic acid--DNA | CRISPR | Myeloid cells | Myeloid leukemia | Transgenic mice | Runx1 protein | Gene expression | Monocytes | Stem cells | Genetic engineering | Mutation | Leukocytes (granulocytic) | Acute myeloid leukemia | Integrity | Index Medicus | Deoxyribonucleic acid | DNA
Journal Article
Journal Article
Blood, ISSN 0006-4971, 07/2014, Volume 124, Issue 3, pp. 393 - 402
Bone morphogenetic protein (BMP) signaling regulates early hematopoietic development, proceeding from mesoderm patterning through the progressive commitment... 
C/EBP-ALPHA | EMBRYONIC STEM-CELLS | KINASE | GENE-EXPRESSION | SELF-RENEWAL | BONE MORPHOGENETIC PROTEIN-4 | DIFFERENTIATION | WNT | HEMATOLOGY | PU.1 | BLOOD | Bone Morphogenetic Proteins - antagonists & inhibitors | Embryonic Stem Cells - metabolism | RNA, Small Interfering - genetics | CCAAT-Enhancer-Binding Protein-alpha - metabolism | Embryonic Stem Cells - cytology | Receptors, Notch - metabolism | Myelopoiesis - genetics | Intracellular Signaling Peptides and Proteins - metabolism | Mesoderm - cytology | Gene Knockdown Techniques | MAP Kinase Signaling System | Embryoid Bodies - metabolism | Intercellular Signaling Peptides and Proteins - metabolism | Bone Morphogenetic Protein Receptors - antagonists & inhibitors | Bone Morphogenetic Proteins - metabolism | Embryoid Bodies - cytology | Smad5 Protein - metabolism | Smad1 Protein - genetics | Myeloid Progenitor Cells - cytology | Membrane Proteins - metabolism | p38 Mitogen-Activated Protein Kinases - metabolism | Smad5 Protein - genetics | Myelopoiesis - drug effects | Pyrazoles - pharmacology | Myeloid Progenitor Cells - metabolism | Myelopoiesis - physiology | Smad5 Protein - antagonists & inhibitors | Cells, Cultured | Bone Morphogenetic Protein Receptors - metabolism | Pyrimidines - pharmacology | Smad1 Protein - antagonists & inhibitors | Embryoid Bodies - drug effects | Animals | Embryonic Stem Cells - drug effects | Myeloid Progenitor Cells - drug effects | Signal Transduction - drug effects | Smad1 Protein - metabolism | Mesoderm - metabolism | Mice | Smad Proteins - metabolism | Index Medicus | Abridged Index Medicus | Hematopoiesis and Stem Cells
Journal Article
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 2017, Volume 292, Issue 39, pp. 16044 - 16054
Journal Article
Nature Immunology, ISSN 1529-2908, 2017, Volume 18, Issue 6, pp. 694 - 704
The transcription factor STAT5 has a critical role in B cell acute lymphoblastic leukemia (B-ALL). How STAT5 mediates this effect is unclear. Here we found... 
MAINTENANCE | ACTIVATION | PROTEIN | DISRUPTION | SUPER-ENHANCERS | IKAROS | ACUTE LYMPHOBLASTIC-LEUKEMIA | RECEPTOR | IMMUNOLOGY | NF-KAPPA-B | EXPRESSION | Prognosis | Humans | Gene Expression Regulation, Neoplastic | Protein Kinase C beta - genetics | B-Lymphocytes | Precursor Cell Lymphoblastic Leukemia-Lymphoma - mortality | NF-kappa B p50 Subunit - genetics | Ikaros Transcription Factor - genetics | Precursor Cell Lymphoblastic Leukemia-Lymphoma - metabolism | STAT5 Transcription Factor - metabolism | Protein-Tyrosine Kinases - genetics | Flow Cytometry | Chromatin Immunoprecipitation | Trans-Activators - genetics | Pre-B Cell Receptors - genetics | Real-Time Polymerase Chain Reaction | Signal Transduction | PAX5 Transcription Factor - genetics | Interferon Regulatory Factors - genetics | Proto-Oncogene Proteins - genetics | Survival Rate | Multiplex Polymerase Chain Reaction | Precursor Cell Lymphoblastic Leukemia-Lymphoma - genetics | Animals | Adaptor Proteins, Signal Transducing - genetics | Mice | Care and treatment | Immune response | Development and progression | STAT5 | Genetic aspects | Acute lymphocytic leukemia | Health aspects | Protein kinase C | Transcription factors | Ikaros protein | Acute lymphatic leukemia | Cell survival | Leukemia | Gene regulation | T cell receptors | Stat5 protein | Lymphatic leukemia | B-cell receptor | Gene expression | Pax5 protein | Bruton's tyrosine kinase | Defects | Enhancers | PU.1 protein | BLNK protein | Lymphocytes B | Interferon regulatory factor 4 | Index Medicus
Journal Article
Journal of Experimental Medicine, ISSN 0022-1007, 2016, Volume 213, Issue 2, pp. 209 - 223
DNA double-strand breaks (DSBs) activate a canonical DNA damage response, including highly conserved cell cycle checkpoint pathways that prevent cells with... 
MEDICINE, RESEARCH & EXPERIMENTAL | LIGHT-CHAIN RECOMBINATION | SPI-C | ACUTE LYMPHOBLASTIC-LEUKEMIA | BONE-MARROW | V(D)J RECOMBINATION | GENE-EXPRESSION | CYCLE ARREST | DIFFERENTIATION | IMMUNOLOGY | NF-KAPPA-B | PU.1 ETS DOMAIN | Cell Proliferation | Ataxia Telangiectasia Mutated Proteins - metabolism | Protein-Tyrosine Kinases - metabolism | Homeodomain Proteins - metabolism | Precursor Cells, B-Lymphoid - metabolism | Precursor Cells, B-Lymphoid - immunology | Intracellular Signaling Peptides and Proteins - metabolism | DNA Breaks, Double-Stranded | DNA-Binding Proteins - deficiency | DNA-Binding Proteins - metabolism | Signal Transduction - immunology | NF-kappa B p52 Subunit - deficiency | NF-kappa B p52 Subunit - genetics | Gene Rearrangement, B-Lymphocyte, Light Chain | Cell Cycle Checkpoints - immunology | Syk Kinase | Protein-Serine-Threonine Kinases - metabolism | Proto-Oncogene Proteins - metabolism | Mice, Transgenic | DNA-Binding Proteins - genetics | Homeodomain Proteins - genetics | NF-kappa B p52 Subunit - metabolism | Mice, Knockout | Animals | Precursor Cells, B-Lymphoid - cytology | Trans-Activators - metabolism | Ataxia Telangiectasia Mutated Proteins - deficiency | Mice | Adaptor Proteins, Signal Transducing - metabolism | Ataxia Telangiectasia Mutated Proteins - genetics | Pre-B Cell Receptors - metabolism | Index Medicus
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 06/2017, Volume 114, Issue 23, pp. 5800 - 5807
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 1/1997, Volume 94, Issue 2, pp. 569 - 574
Journal Article
Glia, ISSN 0894-1491, 11/2018, Volume 66, Issue 11, pp. 2470 - 2486
Microglia are known to regulate several aspects of the development of the central nervous system. When microglia colonize the spinal cord, from E11.5 in the... 
neurogenesis | development | cell death | microglia | dorsal root ganglia | embryonic macrophage | STEM-CELLS | ACTIVATION | RAT | BOUNDARY CAP CELLS | PROLIFERATION | BINDING PROTEIN | PU.1 | NEUROSCIENCES | NEUROTROPHINS | NEURAL CREST | EXPRESSION | Microglia - metabolism | Embryo, Mammalian | Receptors, Interleukin-8A - genetics | Galectin 3 - metabolism | Ki-67 Antigen - metabolism | Ganglia, Spinal - cytology | Green Fluorescent Proteins - genetics | Receptors, Nerve Growth Factor - metabolism | Tubulin - metabolism | Sensory Receptor Cells - physiology | Cell Death | Trans-Activators - genetics | Female | Histocompatibility Antigens Class II - metabolism | Microfilament Proteins - metabolism | Gene Expression Regulation, Developmental - physiology | Calcium-Binding Proteins - metabolism | Proto-Oncogene Proteins - metabolism | Green Fluorescent Proteins - metabolism | Cytokines - metabolism | Mice, Transgenic | Proto-Oncogene Proteins - genetics | Receptor Protein-Tyrosine Kinases - metabolism | Macrophages - metabolism | Animals | Receptors, Interleukin-8A - metabolism | Trans-Activators - metabolism | Mice | Embryonic development | Neurons | Cell death | Analysis | Macrophages | Ganglion | Fatty acids | Protein binding | Cell proliferation | Brain | Spinal cord | Central nervous system | Glial stem cells | Proteins | Reduction | Embryogenesis | Alterations | PU.1 protein | Dorsal root ganglia | Developmental stages | Sensory neurons | TrkA protein | TrkA receptors | Deprivation | Tropomyosin | Embryos | Ablation | Microglia | Immune systems | Axons | Neural stem cells | TrkB receptors | Index Medicus
Journal Article
Cell, ISSN 0092-8674, 05/2018, Volume 173, Issue 4, pp. 920 - 933.e13
Inflammasome activation is critical for host defenses against various microbial infections. Activation of the NLRC4 inflammasome requires detection of... 
Salmonella | ICSBP | NLR | inflammasome | IRF8 | NLRC4 | Burkholderia | caspase-1 | PU.1 | NAIP | IFN | AIM2 INFLAMMASOME | INNATE IMMUNE RECOGNITION | GASDERMIN D | DENDRITIC CELLS | BIOCHEMISTRY & MOLECULAR BIOLOGY | BACTERIAL LIGANDS | GENE-EXPRESSION | FACTOR-I | SEQUENCE-BINDING-PROTEIN | DIFFERENTIAL ROLES | CELL BIOLOGY | Inflammasomes - metabolism | Interferon Regulatory Factors - antagonists & inhibitors | Neuronal Apoptosis-Inhibitory Protein - genetics | Interferon Regulatory Factors - metabolism | NLR Family, Pyrin Domain-Containing 3 Protein - genetics | Pseudomonas aeruginosa - pathogenicity | RNA Interference | Flagellin - metabolism | Apoptosis Regulatory Proteins - genetics | Transcription, Genetic | Electrophoretic Mobility Shift Assay | Macrophages - microbiology | Calcium-Binding Proteins - metabolism | Promoter Regions, Genetic | Pyroptosis | Cytokines - metabolism | Salmonella typhimurium - pathogenicity | NLR Family, Pyrin Domain-Containing 3 Protein - metabolism | Cells, Cultured | Interferon Regulatory Factors - genetics | Macrophages - cytology | Neuronal Apoptosis-Inhibitory Protein - metabolism | Apoptosis Regulatory Proteins - metabolism | Macrophages - metabolism | Animals | Protein Binding | Mice | Calcium-Binding Proteins - genetics | RNA, Small Interfering - metabolism | Interferon | Bacterial infections | Genetic transcription | Biological response modifiers | Index Medicus | infection | SPI1 | ALR | infectious diseases | immunity | Pseudomonas | type I interferon | interferon regulatory factor | pathogen | IRF
Journal Article