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science & technology (116) 116
life sciences & biomedicine (115) 115
pxr (102) 102
humans (85) 85
pharmacology & pharmacy (60) 60
pregnane x receptor (46) 46
animals (45) 45
receptors, steroid - genetics (45) 45
receptors, steroid - metabolism (42) 42
car (36) 36
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female (26) 26
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adult (18) 18
gene expression (18) 18
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biochemistry & molecular biology (17) 17
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liver - metabolism (16) 16
polymorphism, single nucleotide (16) 16
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cytochrome p-450 cyp3a - genetics (14) 14
metabolism (14) 14
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cancer (13) 13
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physiological aspects (13) 13
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cytochrome p-450 (11) 11
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genetic aspects (11) 11
induction (11) 11
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oncology (11) 11
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xenobiotics - metabolism (11) 11
analysis (10) 10
cell biology (10) 10
cytochrome p-450 cyp3a - biosynthesis (10) 10
digestive system diseases (10) 10
genotype (10) 10
liver (10) 10
proteins (10) 10
review (10) 10
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cytochrome p-450 enzyme system - metabolism (9) 9
fxr (9) 9
gastroenterology & hepatology (9) 9
gene expression regulation - drug effects (9) 9
life sciences (9) 9
p-glycoprotein (9) 9
rats (9) 9
biomedicine (8) 8
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cytochrome p-450 enzyme system - genetics (8) 8
cytochrome p450 (8) 8
hepatocytes - metabolism (8) 8
neoplasms - drug therapy (8) 8
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rna, messenger - metabolism (8) 8
transcription factors - metabolism (8) 8
biology (7) 7
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gene frequency (7) 7
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young adult (7) 7
atp-binding cassette, sub-family b, member 1 - genetics (6) 6
bile acids (6) 6
cyp3a (6) 6
drug resistance (6) 6
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Journal Article
International journal of cancer, ISSN 0020-7136, 08/2012, Volume 131, Issue 4, pp. 803 - 812
Journal Article
Journal of acquired immune deficiency syndromes (1999), ISSN 1525-4135, 12/2010, Volume 55, Issue 5, pp. 536 - 549
HIV protease inhibitor | polymorphism | drug interactions | PXR | CYP450 | antiretroviral therapy | Infectious Diseases | Immunology | Life Sciences & Biomedicine | Science & Technology | Fundamental and applied biological sciences. Psychology | Miscellaneous | Infectious diseases | Microbiology | Viral diseases | Biological and medical sciences | Medical sciences | Human viral diseases | Epidemiology | Virology | Anti-HIV Agents - pharmacology | Aryl Hydrocarbon Hydroxylases - biosynthesis | Oxidoreductases, N-Demethylating - genetics | Humans | Middle Aged | Aryl Hydrocarbon Hydroxylases - genetics | Reverse Transcriptase Inhibitors - pharmacology | Male | HIV Protease Inhibitors - pharmacology | Drug Interactions | Cytochrome P-450 CYP3A - genetics | Adult | Anti-HIV Agents - therapeutic use | Female | African Continental Ancestry Group - genetics | Reverse Transcriptase Inhibitors - therapeutic use | Cell Line | Cytochrome P-450 CYP3A - biosynthesis | Promoter Regions, Genetic | European Continental Ancestry Group - genetics | HIV Infections - genetics | Africa South of the Sahara | Genotype | HIV Protease Inhibitors - therapeutic use | Hep G2 Cells | Androstanes | Receptors, Steroid - genetics | HIV Infections - drug therapy | Polymorphism, Single Nucleotide | Oxidoreductases, N-Demethylating - biosynthesis | Pregnane X Receptor | Cytochrome P-450 CYP2B6 | Antiretroviral drugs | Acquired immune deficiency syndrome--AIDS | Drug therapy | Gene expression | Human immunodeficiency virus--HIV | Polymorphism | Index Medicus | AIDS/HIV
Journal Article
Journal Article
Journal of hepatology, ISSN 0168-8278, 2012, Volume 58, Issue 1, pp. 155 - 168
Gastroenterology and Hepatology | Gallstones | Liver cancer | Bile acids | Fatty liver disease | Cholestasis | Liver regeneration | Gastroenterology & Hepatology | Life Sciences & Biomedicine | Science & Technology | Animals | Carrier Proteins - metabolism | Cholestasis - metabolism | Membrane Glycoproteins - metabolism | Humans | Liver - metabolism | Bile Acids and Salts - metabolism | Liver Diseases - metabolism | Liver Regeneration - physiology | Receptors, Cytoplasmic and Nuclear - metabolism | Drug resistance in microorganisms | Corticosteroids | Glucagon | Calcifediol | Ursodiol | Deoxycholic acid | Epidermal growth factor | Vitamin D | Physiological aspects | Fibroblast growth factors | Alfacalcidol | Index Medicus | IBABP (FABP6, ILBP), intestinal bile acid-binding protein, fatty acid-binding protein 6 | PFIC, progressive familial intrahepatic cholestasis | TNFα, tumor necrosis factor α | 3 (human) | SRC2, p160 steroid receptor coactivator | NAFLD, non-alcoholic fatty liver disease | BA, bile acid | bile acid receptor | 8, cholesterol efflux pump, ATP-binding cassette, subfamily G, member 5 | UDCA, ursodeoxycholic acid | LRH-1 (NR5A2), liver receptor homolog-1 | LCA, lithocholic acid | LXRα (NR1H3), liver X receptor alpha | PPARγ (NR1C3), peroxisome proliferator-activated receptor gamma | OSTαβ, organic solute transporter alpha | ABCG5 | AMPK, AMP activated protein kinase | NASH, non-alcoholic steatohepatitis | SHP (NR0B2), short heterodimer partner | OATP1A2 (SLCO1A2, OATP1, OATP-A, SLC21A3), solute carrier organic anion transporter family, member 1A2 | EGFR, epidermal growth factor receptor | IL6, interleukin 6 | TGR5, G protein-coupled bile acid receptor | PH, partial hepatectomy | AE2, anion exchanger 2 | PSC, primary sclerosing cholangitis | OATP1B1 (SLCO1B1, OATP2, OATP-C, SLC21A6), solute carrier organic anion transporter family, member 1B1 | RARα (NR1B1), retinoic acid receptor alpha | GLP-1, glucagon like peptide 1 | VDR (NR1I1), vitamin D receptor. Please note that for the convenience of better readability and clarity, abbreviations for transporters and nuclear receptors were capitalized throughout this article when symbols were identical for human and rodents | MRP2 (ABCC2), multidrug resistance-associated protein 2, ATP-binding cassette, subfamily C, member 2 | NTCP (SLC10A1), sodium | CAR (NR1I3), constitutive androstane receptor | taurocholate cotransporting polypeptide, solute carrier family 10, member 1 | PPARα (NR1C1), peroxisome proliferator-activated receptor alpha | Review | GR (NR3C1), glucocorticoid receptor | Bile acids, Cholestasis, Fatty liver disease, Gallstones, Liver regeneration, Liver cancer | 19, fibroblast growth factor 15 | Mdr2 | ICP, intrahepatic cholestasis of pregnancy | BRIC, benign recurrent intrahepatic cholestasis | OATP1B3 (SLCO1B3, OATP8, SLC21A8), solute carrier organic anion transporter family, member 1B3 | MRP3 (ABCC3), multidrug resistance-associated protein 3, ATP-binding cassette, subfamily C, member 3 | beta | MDR1 (ABCB1), p-glycoprotein, ATP-binding cassette, subfamily B, member 1 | norUDCA, norursodeoxycholic acid | 6-ECDCA, 6-ethylchenodeoxycholic acid | FXR (NR1H4), farnesoid X receptor | BCRP (ABCG2), breast cancer resistance protein, ATP-binding cassette, subfamily G, member 2 | HNF4α (NR2A1), hepatocyte nuclear factor 4 alpha | PBC, primary biliary cirrhosis | MDR3 (ABCB4), multidrug resistance protein 2 (rodents) | HNF1α, hepatocyte nuclear factor 1 alpha | NR, nuclear receptor | FGF15 | RXRα (NR2B1), retinoid X receptor alpha | PXR (NR1I2), pregnane X receptor | BSEP (ABCB11), bile salt export pump | HCC, hepatocellular carcinoma | MRP4 (ABCC4), multidrug resistance-associated protein 4, ATP-binding cassette, subfamily C, member 4 | TPN, total parenteral nutrition
Journal Article