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Analytical Biochemistry, ISSN 0003-2697, 04/2019, Volume 570, pp. 27 - 31
Previously, we developed a kinase cycling method using creatine kinase and pyruvate kinase (RMPK) both from rabbit muscle in the presence of an excess amount... 
Pyruvate kinase | preference | Enzymatic cycling
Journal Article
ELIFE, ISSN 2050-084X, 07/2017, Volume 6
Journal Article
Journal of Infectious Diseases, ISSN 0022-1899, 07/2017, Volume 216, Issue 2, p. 276
Journal Article
Biochemistry, ISSN 0006-2960, 8/2016, Volume 55, Issue 33, pp. 4731 - 4736
Human pyruvate kinase isoform M2 (PKM2) is a glycolytic enzyme isoform implicated in cancer. Malignant cancer cells have higher levels of dimeric PKM2, which... 
Pyruvate kinase | SAICAR | Quaternary structure
Journal Article
Toxins, ISSN 2072-6651, 06/2019, Volume 11, Issue 7, p. 379
Antimalarial drug resistance is an enormous global threat. Recently, antimicrobial peptides (AMPs) are emerging as a new source of antimalarials. In this... 
cytokine | antimicrobial peptide | malaria | ATP | pyruvate kinase
Journal Article
Critical Reviews in Food Science and Nutrition, ISSN 1040-8398, 06/2019, Volume 59, Issue sup1, pp. S153 - S161
Methicillin-resistant Staphylococcus aureus (MRSA) is a notorious bacterial pathogen that induces high mortality and morbidity. Due to the emergence of... 
plant antimicrobials | efflux pump | quorum sensing | MRSA | pyruvate kinase
Journal Article
12/2009
Background: Recent studies have confirmed that alterations in the isoenzyme of pyruvate kinase (PK) provide tumor cells with selective growth advantage. Aims:... 
human brain | Alanine inhibition | astrocytomas | isozymes | pyruvate kinase
Web Resource
Circulation, ISSN 0009-7322, 10/2017, Volume 136, Issue 25, pp. 2468 - 2485
BACKGROUND—An emerging 'metabolic theory' of pulmonary hypertension (PH) suggests that cellular and mitochondrial metabolic dysfunction underlies the pathology... 
splicing factors | hypoxia | Shikonin | mitochondria | pyruvate kinase | TEPP-46 | metabolism
Journal Article
LANCET, ISSN 0140-6736, 01/2008, Volume 371, Issue 9606, pp. 64 - 74
Glucose-6-phosphate dehydrogenase (G6PD) deficiency is the most common human enzyme defect, being present in more than 400 million people worldwide. The global... 
HEMOLYTIC-ANEMIA | MOLECULAR CHARACTERIZATION | MALARIA-G-6-PD HYPOTHESIS | SEVERE NEONATAL HYPERBILIRUBINEMIA | SEQUENCE-ANALYSIS | MEDICINE, GENERAL & INTERNAL | G6PD DEFICIENCY | PLASMODIUM-FALCIPARUM | PYRUVATE-KINASE DEFICIENCY | RED-CELLS | GLUCOSE-6-PHOSPHATE-DEHYDROGENASE DEFICIENCY
Journal Article
12/2011
Aim of the Study: The aim of this study was to evaluate platelet enzyme activity in cases of leukemia. Materials and Methods: Platelet enzymes... 
leukemia | glucose-6-phosphate dehydrogenase | platelet enzyme abnormalities | pyruvate kinase | chronic myeloid leukemia | Acute myeloid leukemia | hexokinase
Web Resource
by Bian, ZH and Zhang, JW and Li, M and Feng, YY and Wang, X and Zhang, J and Yao, SR and Jin, GY and Du, J and Han, WF and Yin, Y and Huang, SL and Fei, BJ and Zou, J and Huang, ZH
CLINICAL CANCER RESEARCH, ISSN 1078-0432, 10/2018, Volume 24, Issue 19, pp. 4808 - 4819
Purpose: Long non-coding RNAs (lncRNAs) play key roles in human cancers. Here, FEZFl-AS1, a highly overexpressed lncRNA in colorectal cancer, was identified by... 
COLON-CANCER | LONG NONCODING RNA | ONCOLOGY | GASTRIC-CANCER | PATHWAY | POOR-PROGNOSIS | PYRUVATE-KINASE M2 | TRANSCRIPTION | CELL-PROLIFERATION | IDENTIFICATION | CARCINOMA
Journal Article
Clinics and Research in Hepatology and Gastroenterology, ISSN 2210-7401, 07/2019
BACKGROUNDAlthough pyruvate kinase M2 (PKM2) has been shown to be among the crucial enzymes that regulate aerobic glycolysis in multiple tumour cells, its role... 
Journal Article
Chinese Journal of Applied Ecology, ISSN 1001-9332, 11/2017, Volume 28, Issue 11, pp. 3521 - 3526
Journal Article
Nature Cell Biology, ISSN 1465-7392, 02/2015, Volume 17, Issue 2, pp. 183 - 194
Journal Article
GASTROENTEROLOGY, ISSN 0016-5085, 02/2016, Volume 150, Issue 2, pp. 328 - 339
Intracellular components must be recycled for cells to maintain energy and ensure quality control of proteins and organelles. Autophagy is a highly conserved... 
LIPID-METABOLISM | Lysosome | LIVER AUTOPHAGY | Macroautophagy | YEAST SACCHAROMYCES-CEREVISIAE | LYSOSOMAL PROTEOLYSIS | HEPATOCELLULAR-CARCINOMA | Lipophagy | PYRUVATE-KINASE | Chaperone-Mediated Autophagy | CALORIC RESTRICTION | CYTOSOLIC PROTEINS | GASTROENTEROLOGY & HEPATOLOGY | Cancer | DEFECTIVE HEPATIC AUTOPHAGY
Journal Article
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