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New BIOTECHNOLOGY, ISSN 1871-6784, 05/2014, Volume 31, Issue 3, pp. 242 - 245
Plants are capable of producing a wide variety of secondary metabolites which have a diverse range of functions that can be exploited for medicinal purposes;... 
NATURAL-PRODUCT | TAXADIENE | TAXA-4,11-DIENE | PLANT-CELL CULTURE | ISOPRENOID BIOSYNTHESIS | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | TAXOL | RING | TAXUS | BIOCHEMICAL RESEARCH METHODS | 1ST TOTAL-SYNTHESIS | Paclitaxel - chemistry | Biosynthetic Pathways | Paclitaxel - biosynthesis | Humans | Physiological aspects | Paclitaxel
Journal Article
Nature, ISSN 0028-0836, 01/2011, Volume 469, Issue 7328, pp. 116 - 122
Journal Article
Fungal Diversity, ISSN 1560-2745, 5/2013, Volume 60, Issue 1, pp. 161 - 170
Journal Article
Oncology Reports, ISSN 1021-335X, 12/2012, Volume 28, Issue 6, pp. 2091 - 2100
Journal Article
Applied Microbiology and Biotechnology, ISSN 0175-7598, 10/2001, Volume 57, Issue 1, pp. 13 - 19
Journal Article
Nature Communications, ISSN 2041-1723, 12/2019, Volume 10, Issue 1, pp. 1 - 12
Production of the anticancer drug Taxol and its precursors in heterologous hosts is more sustainable than extraction from tissues of yew trees or chemical... 
Cytochrome | Reductases | Taxol | Hydroxylase | Cytochrome P450 | Yew | Biosynthesis | NADPH-ferrihemoprotein reductase | Metabolism | Intermediates | Engineering | Organic chemistry | Precursors | Paclitaxel | Metabolic engineering | Chemical synthesis | Taxanes | Cytochromes P450 | Reductase
Journal Article
The Journal of Immunology, ISSN 0022-1767, 01/2001, Volume 166, Issue 1, pp. 574 - 581
Overproduction of inflammatory mediators by macrophages in response to Gram-negative LPS has been implicated in septic shock. Recent reports indicate that... 
SIGNAL-TRANSDUCTION | BACTERIAL LIPOPOLYSACCHARIDE | TYROSINE PHOSPHORYLATION | IMMUNE-RESPONSES | MURINE MACROPHAGES | ENDOTHELIAL-CELLS | IMMUNOLOGY | SEQUENCE-BINDING PROTEIN | DEPENDENT MECHANISMS | NF-KAPPA-B | CUTTING EDGE | Prostaglandin-Endoperoxide Synthases - biosynthesis | Interferon Regulatory Factors | Toll-Like Receptor 4 | Tumor Necrosis Factor-alpha - genetics | NF-kappa B - metabolism | Interferon-gamma - metabolism | CD11 Antigens - genetics | CD11 Antigens - biosynthesis | Toll-Like Receptors | Membrane Glycoproteins - physiology | Receptors, Cell Surface - physiology | Chemokines, CXC - biosynthesis | p38 Mitogen-Activated Protein Kinases | Interleukin-12 - biosynthesis | Adjuvants, Immunologic - physiology | NF-kappa B - antagonists & inhibitors | CD18 Antigens - genetics | Isoenzymes - genetics | Repressor Proteins - genetics | Macrophages - enzymology | Mice, Knockout | Macrophages - metabolism | Repressor Proteins - biosynthesis | Lipopolysaccharides - pharmacology | Active Transport, Cell Nucleus - immunology | Mice | Tumor Necrosis Factor-alpha - biosynthesis | CD18 Antigens - physiology | Phosphorylation | Paclitaxel - pharmacology | Interleukin-12 - genetics | Cyclooxygenase 2 | Interleukin-12 - antagonists & inhibitors | JNK Mitogen-Activated Protein Kinases | Adjuvants, Immunologic - genetics | CD11 Antigens - physiology | Macrophages - immunology | Prostaglandin-Endoperoxide Synthases - genetics | Drosophila Proteins | Lipopolysaccharide Receptors - physiology | Gene Expression Regulation - immunology | Mice, Inbred C57BL | Cells, Cultured | Interferon-gamma - physiology | Adjuvants, Immunologic - biosynthesis | Chemokines, CXC - genetics | Chemokine CXCL10 | Cyclooxygenase Inhibitors - pharmacology | Gene Expression Regulation - drug effects | Animals | Cyclooxygenase 2 Inhibitors | Macrophages - drug effects | Isoenzymes - biosynthesis | CD18 Antigens - biosynthesis | Mitogen-Activated Protein Kinases - metabolism
Journal Article