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1. Full Text Cellular uptake of solid lipid nanoparticles and cytotoxicity of encapsulated paclitaxel in A549 cancer cells
by Yuan, Hong and Miao, Jing and Du, Yong-Zhong and You, Jian and Hu, Fu-Qiang and Zeng, Su
International Journal of Pharmaceutics, ISSN 0378-5173, 2008, Volume 348, Issue 1, pp. 137 - 145
The aim of this study was to investigate the cellular uptake of solid lipid nanoparticles (SLN) and cytotoxicity of its paclitaxel delivery system. The... 
Fluorescein isothiocyanate | Cytotoxicity | Cellular uptake | Polyethylene glycol monostearate | Solid lipid nanoparticles | Folic acid | SYSTEM | solid lipid nanoparticles | DOXORUBICIN | cellular uptake | DELIVERY | polyethylene glycol monostearate | LINE | PHARMACOLOGY & PHARMACY | ANTICANCER DRUGS | PARTICLE-SIZE | folic acid | fluorescein isothiocyanate | EFFICIENCY | cytotoxicity | Amines - chemistry | Paclitaxel - pharmacology | Nanoparticles - chemistry | Humans | Polyethylene Glycols - chemistry | Paclitaxel - pharmacokinetics | Triglycerides - chemistry | Paclitaxel - chemistry | Lipids - chemistry | Fluorescein-5-isothiocyanate - chemistry | Surface Properties | Inhibitory Concentration 50 | Antineoplastic Agents, Phytogenic - pharmacokinetics | Stearates - chemistry | Cell Survival - drug effects | Glycerides - chemistry | Fatty Acids - chemistry | Folic Acid - chemistry | Antineoplastic Agents, Phytogenic - chemistry | Static Electricity | Stearic Acids - chemistry | Particle Size | Cell Line, Tumor | Cell Proliferation - drug effects | Antineoplastic Agents, Phytogenic - pharmacology | Glycerin | Nanoparticles | Care and treatment | Polyethylene glycol | Fluorescein | Fluorescence | Glycerol | Nanotechnology | Cancer
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2. Full Text Use of a Lipid-Coated Mesoporous Silica Nanoparticle Platform for Synergistic Gemcitabine and Paclitaxel Delivery to Human Pancreatic Cancer in Mice
by Meng, Huan and Wang, Meiying and Liu, Huiyu and Liu, Xiangsheng and Situ, Allen and Wu, Bobby and Ji, Zhaoxia and Chang, Chong Hyun and Nel, Andre E
ACS Nano, ISSN 1936-0851, 04/2015, Volume 9, Issue 4, pp. 3540 - 3557
Recently, a commercial albumin-bound paclitaxel (PTX) nanocarrier (Abraxane) was approved as the first new drug for pancreatic ductal adenocarcinoma in almost... 
SUPPORTED MEMBRANES | paclitaxel | PHYSICAL-PROPERTIES | synergy | mesoporous silica nanoparticle | VIVO | NAB-PACLITAXEL | MATERIALS SCIENCE, MULTIDISCIPLINARY | CHEMISTRY, PHYSICAL | NANOSCIENCE & NANOTECHNOLOGY | MODEL | CYTIDINE DEAMINASE | CHEMISTRY, MULTIDISCIPLINARY | OVERCOME DRUG-RESISTANCE | co-delivery | pancreatic cancer | IN-VITRO | ratiometric | gemcitabine | BILAYERS PROTOCELLS | NANOTECHNOLOGY | Albumins - chemistry | Deoxycytidine - chemistry | Paclitaxel - pharmacology | Pancreatic Neoplasms - metabolism | Nanoparticles - chemistry | Humans | Deoxycytidine - pharmacology | Antineoplastic Agents - therapeutic use | Drug Carriers - chemistry | Pancreatic Neoplasms - drug therapy | Albumins - therapeutic use | Paclitaxel - chemistry | Deoxycytidine - therapeutic use | Female | Antineoplastic Agents - pharmacology | Gene Expression Regulation, Neoplastic - drug effects | Pancreatic Neoplasms - pathology | Silicon Dioxide - chemistry | Antineoplastic Agents - chemistry | Paclitaxel - therapeutic use | Drug Synergism | Albumins - pharmacology | Animals | Cell Transformation, Neoplastic | Cytidine Deaminase - metabolism | Cell Line, Tumor | Mice | Lipid Bilayers - chemistry | Porosity | Deoxycytidine - analogs & derivatives | Index Medicus | Drugs | Effectiveness | Metabolites | Biocompatibility | Lipids | Nanostructure | Tumors | Cancer
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3. Full Text "triple-punch" strategy for triple negative breast cancer therapy with minimized drug dosage and improved antitumor efficacy
by Su, Shishuai and Tian, Yanhua and Li, Yiye and Ding, Yanping and Ji, Tianjiao and Wu, Meiyu and Wu, Yan and Nie, Guangjun
ACS Nano, ISSN 1936-0851, 02/2015, Volume 9, Issue 2, pp. 1367 - 1378
Effective therapeutics against triple negative breast cancer (TNBC), which has no standard-of-care therapy, needs to be developed urgently. Here we... 
thermoresponsive | triple negative breast cancer | combination antitumor therapy | INDOCYANINE GREEN | CELLS | SURVIVIN | MATERIALS SCIENCE, MULTIDISCIPLINARY | DOXORUBICIN | CHEMISTRY, PHYSICAL | NANOSCIENCE & NANOTECHNOLOGY | MICELLES | RELEASE | CHEMISTRY, MULTIDISCIPLINARY | PACLITAXEL | NANOPARTICLES | CO-DELIVERY | INHIBITION | RNA, Small Interfering - genetics | Paclitaxel - pharmacology | Nanoparticles - chemistry | Inhibitor of Apoptosis Proteins - genetics | Humans | Polyethylene Glycols - chemistry | Antineoplastic Agents - therapeutic use | Methacrylates - chemistry | Triple Negative Breast Neoplasms - drug therapy | Drug Carriers - chemistry | RNA, Small Interfering - chemistry | Indocyanine Green - chemistry | Inhibitor of Apoptosis Proteins - deficiency | Paclitaxel - chemistry | Endocytosis | Triple Negative Breast Neoplasms - pathology | Female | Antineoplastic Agents - pharmacology | Drug Carriers - metabolism | Lactic Acid - chemistry | Antineoplastic Agents - chemistry | Paclitaxel - therapeutic use | Animals | Triple Negative Breast Neoplasms - genetics | Intracellular Space - metabolism | Nanomedicine - methods | Polyglycolic Acid - chemistry | Cell Line, Tumor | Drug Carriers - pharmacokinetics | Mice | Mice, Inbred BALB C
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4. Full Text Hybrid nanoparticles improve targeting to inflammatory macrophages through phagocytic signals
by Bagalkot, Vaishali and Badgeley, Marcus A and Kampfrath, Thomas and Deiuliis, Jeffrey A and Rajagopalan, Sanjay and Maiseyeu, Andrei
Journal of Controlled Release, ISSN 0168-3659, 11/2015, Volume 217, pp. 243 - 255
Macrophages are innate immune cells with great phenotypic plasticity, which allows them to regulate an array of physiological processes such as host defense,... 
Obesity | Theranostic nanoparticles | Intravital imaging | Inflammation | Magnetic resonance imaging | Atherosclerosis | CORE-SHELL NANOPARTICLES | ATHEROSCLEROTIC PLAQUES | CONTRAST AGENTS | DRUG-DELIVERY | PHOSPHOLIPASE A | CHEMISTRY, MULTIDISCIPLINARY | ENDOTHELIAL-CELLS | INTRACELLULAR DELIVERY | PPAR-GAMMA | PHARMACOLOGY & PHARMACY | EXPRESSION | ADIPOSE-TISSUE | Nanoparticles - chemistry | Obesity - immunology | Polyethylene Glycols - chemistry | Thiazolidinediones - chemistry | Thiazolidinediones - administration & dosage | Tamoxifen - administration & dosage | Polystyrenes - chemistry | Cholesterol - chemistry | Paclitaxel - chemistry | Fluorescein-5-isothiocyanate - chemistry | Tamoxifen - chemistry | Anti-Inflammatory Agents - administration & dosage | Paclitaxel - administration & dosage | Cytokines - genetics | Macrophages - immunology | Phospholipases A2 - chemistry | Cell Line | Cholesterol - analogs & derivatives | Atherosclerosis - immunology | Mice, Inbred C57BL | Phosphatidylserines - chemistry | Gadolinium - chemistry | Mice, Knockout | Animals | Anti-Inflammatory Agents - chemistry | Apolipoproteins E - genetics | Macrophages - drug effects | Nanoparticles - administration & dosage | Phosphatidylethanolamines - chemistry | Phagocytosis | Nanoparticles | Drugs | Drug delivery systems | Physiological aspects | Lipids | Macrophages | Vehicles | Fluorescein | Cardiovascular agents
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5. Full Text Reversible Lysine Modification on Proteins by Using Functionalized Boronic Acids
by Cal, Pedro M. S. D and Frade, Raquel F. M and Cordeiro, Carlos and Gois, Pedro M. P
Chemistry – A European Journal, ISSN 0947-6539, 05/2015, Volume 21, Issue 22, pp. 8182 - 8187
Iminoboronates have been utilized to successfully install azide and alkyne bioorthogonal functions on proteins, which may then be further reacted with their... 
cycloaddition | protein modifications | drug design | conjugation | boronic acids | FOLATE RECEPTOR | BONDS | CHEMISTRY | SYSTEMS | CANCER | CHEMISTRY, MULTIDISCIPLINARY | DELIVERY | Cell Line | Paclitaxel - pharmacology | Muramidase - chemistry | Humans | Folic Acid - chemistry | Models, Molecular | Antineoplastic Agents, Phytogenic - chemistry | Polyethylene Glycols - chemistry | Alkynes - chemistry | Boronic Acids - chemistry | Azides - chemistry | Neoplasms - drug therapy | Paclitaxel - chemistry | Animals | Insulin - chemistry | Imines - chemistry | Cell Line, Tumor | Proteins - chemistry | Antineoplastic Agents, Phytogenic - pharmacology | Lysine - chemistry | Proteins | Drugstores | Lysine | Polyols | Pharmacy | Fructose | Acids | Polyethylene glycol | Drugs | Conjugates | Strategy | Folic acid
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6. Full Text Hyaluronic acid-decorated poly(lactic-co-glycolic acid) nanoparticles for combined delivery of docetaxel and tanespimycin
by Pradhan, Roshan and Ramasamy, Thiruganesh and Choi, Ju Yeon and Choi, Han-Gon and Kim, Jong Oh and Kim, Jeong Hwan and Poudel, Bijay Kumar and Tak, Jin Wook and Nukolova, Natalia and Yong, Chul Soon
Carbohydrate Polymers, ISSN 0144-8617, 06/2015, Volume 123, pp. 313 - 323
Multiple-drug combination therapy is becoming more common in the treatment of advanced cancers because this approach can decrease side effects and delay or... 
Tanespimycin | Combined therapy | Poly(lactic-co-glycolic acid) | Docetaxel | Synergic effect | POLYMER SCIENCE | SELF-ASSEMBLED NANOPARTICLES | CHEMISTRY, ORGANIC | ANTICANCER DRUG | MICELLES | FORMULATION | CANCER | PACLITAXEL | PHASE-II TRIAL | CO-DELIVERY | 17-ALLYLAMINO-17-DEMETHOXYGELDANAMYCIN | CHEMISTRY, APPLIED | PLGA NANOPARTICLES | Taxoids - toxicity | Benzoquinones - administration & dosage | Nanoparticles - chemistry | Humans | Body Weight - drug effects | Transplantation, Heterologous | Benzoquinones - chemistry | Antineoplastic Agents - administration & dosage | Drug Carriers - chemistry | Antineoplastic Agents - toxicity | Lactams, Macrocyclic - chemistry | Water - chemistry | Benzoquinones - toxicity | Lactams, Macrocyclic - administration & dosage | Oils - chemistry | Taxoids - chemistry | Cell Survival - drug effects | Lactic Acid - chemistry | Emulsions - chemistry | Hyaluronic Acid - chemistry | Antineoplastic Agents - chemistry | Lactams, Macrocyclic - toxicity | Particle Size | Microscopy, Confocal | Taxoids - administration & dosage | Animals | Carcinoma, Squamous Cell - drug therapy | Mice, Nude | Polyglycolic Acid - chemistry | Cell Line, Tumor | Mice | Antimitotic agents | Drugstores | Antineoplastic agents | Hyaluronic acid | Pharmacy
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7. Full Text Effect of HM30181 mesylate salt-loaded microcapsules on the oral absorption of paclitaxel as a novel P-glycoprotein inhibitor
by Kim, Dong Wuk and Kim, Yong Il and Kim, Dong Shik and Kim, Jin Cheul and Kim, Jong Oh and Kim, Kyeong Soo and Jin, Sung Giu and Park, Jae-Hyun and Yong, Chul Soon and Youn, Yu Seok and Woo, Jong Soo and Choi, Han-Gon
International Journal of Pharmaceutics, ISSN 0378-5173, 06/2016, Volume 506, Issue 1-2, pp. 93 - 101
The purpose of this study was to develop HM30181 mesylate salt (HM30181M)-loaded microcapsules as a novel P-glycoprotein inhibitor for enhancing the oral... 
HM30181 mesylate salt | Bioavailability | Microcapsule | Paclitaxel | Solubility | P-glycoprotein inhibitor | CANCER-CELLS | DRUG-DELIVERY SYSTEM | SOLID DISPERSION | RATS | DOCETAXEL | NANOPARTICLES | ENHANCED STABILITY | PHYSICOCHEMICAL CHARACTERIZATION | BETA-CYCLODEXTRIN | PHARMACOLOGY & PHARMACY | Paclitaxel - metabolism | Paclitaxel - pharmacology | Capsules - pharmacology | Lactose - analogs & derivatives | Capsules - metabolism | Methylcellulose - analogs & derivatives | Biological Availability | Male | Drug Carriers - chemistry | Benzopyrans - chemistry | Isoquinolines - chemistry | Paclitaxel - chemistry | Tetrazoles - chemistry | ATP Binding Cassette Transporter, Sub-Family B - antagonists & inhibitors | Powders - pharmacology | Administration, Oral | Silicon Dioxide - chemistry | Phosphoric Acids - chemistry | Rats | Capsules - chemistry | Mesylates - chemistry | Rats, Sprague-Dawley | Powders - chemistry | Methylcellulose - chemistry | Animals | Lactose - chemistry | Polymers - chemistry | Antimitotic agents | Drugstores | Antineoplastic agents | Pharmacy | Phosphates | Phosphoric acid | Powders | Polymers | Silica
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8. Full Text Exploration of Fluorine Chemistry at the Multidisciplinary Interface of Chemistry and Biology
by Ojima, Iwao
The Journal of Organic Chemistry, ISSN 0022-3263, 07/2013, Volume 78, Issue 13, pp. 6358 - 6383
Over the last three decades, my engagement in “fluorine chemistry” has evolved substantially because of the multidisciplinary nature of the research programs.... 
MEDICINAL CHEMISTRY | BETA-AMINO ACIDS | LACTAM-SYNTHON-METHOD | TARGETING DRUG-DELIVERY | ASYMMETRIC-SYNTHESIS | NEW-GENERATION TAXOIDS | ANTICANCER AGENTS | CHEMISTRY, ORGANIC | ANGIOTENSIN-CONVERTING ENZYME | CARBON NANOTUBES | BOUND PACLITAXEL CONFORMATION | Hydrocarbons, Fluorinated - chemistry | Chemistry | Biology
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9. Full Text Biocompatible Zr-based nanoscale MOFs coated with modified poly(ε-caprolactone) as anticancer drug carriers
by Filippousi, Maria and Turner, Stuart and Leus, Karen and Siafaka, Panoraia I and Tseligka, Eirini D and Vandichel, Matthias and Nanaki, Stavroula G and Vizirianakis, Ioannis S and Bikiaris, Dimitrios N and Van Der Voort, Pascal and Van Tendeloo, Gustaaf
International Journal of Pharmaceutics, ISSN 0378-5173, 07/2016, Volume 509, Issue 1-2, pp. 208 - 218
Nanoscale Zr-based metal organic frameworks (MOFs) UiO-66 and UiO-67 were studied as potential anticancer drug delivery vehicles. Two model drugs were used,... 
Polymer | Drug delivery | SEM | UiO-67 | ADF-STEM | Metal-organic frameworks/UiO-66 | MICROSPHERES | STABILITY | ENCAPSULATION | RELEASE | DELIVERY | NANOPARTICLES | IN-VITRO | METAL-ORGANIC FRAMEWORKS | CISPLATIN | DEGRADATION | PHARMACOLOGY & PHARMACY | Nanoparticles - chemistry | Humans | Coated Materials, Biocompatible - chemistry | Delayed-Action Preparations - chemistry | Polyethylene Glycols - chemistry | Caproates - chemistry | Antineoplastic Agents - administration & dosage | Antineoplastic Agents - chemistry | Drug Carriers - chemistry | Cisplatin - administration & dosage | Delayed-Action Preparations - administration & dosage | Particle Size | Paclitaxel - chemistry | Cisplatin - chemistry | Zirconium - chemistry | Cell Line, Tumor | Hydrophobic and Hydrophilic Interactions | Polymers - chemistry | Vitamin E - chemistry | Paclitaxel - administration & dosage | Drug Delivery Systems - methods | Lactones - chemistry | Antimitotic agents | Drugs | Drug delivery systems | Analysis | Catalysis | Antineoplastic agents | Vehicles | Squamous cell carcinoma | Gliomas | Polyethylene glycol | Polymer industry | Polyols | Index Medicus
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10. Full Text Paclitaxel-loaded PEGylated PLGA-based nanoparticles: In vitro and in vivo evaluation
by Danhier, Fabienne and Lecouturier, Nathalie and Vroman, Benoît and Jérôme, Christine and Marchand-Brynaert, Jacqueline and Feron, Olivier and Préat, Véronique
Journal of Controlled Release, ISSN 0168-3659, 2009, Volume 133, Issue 1, pp. 11 - 17
The purpose of this study was to develop Cremophor EL-free nanoparticles loaded with Paclitaxel (PTX), intended to be intravenously administered, able to... 
PLGA | PEGylated nanoparticle | Anti-tumoral activity | Paclitaxel | CELLS | PHOSPHORYLATION | CREMOPHOR-EL | DRUG-RELEASE | CHEMISTRY, MULTIDISCIPLINARY | CELLULAR UPTAKE | CANCER-THERAPY | DELIVERY | PHARMACOKINETICS | TAXOL | PHARMACOLOGY & PHARMACY | PARTICLE-SIZE | Paclitaxel - pharmacology | Nanoparticles - chemistry | Apoptosis - drug effects | Humans | Ethylene Oxide - chemistry | Male | Polyethylene Glycols - chemistry | Drug Carriers - chemistry | Paclitaxel - chemistry | Flow Cytometry | Glycerol - pharmacology | Antineoplastic Agents, Phytogenic - therapeutic use | Drug Evaluation, Preclinical | Glycerol - analogs & derivatives | Lactones - chemistry | Cell Survival - drug effects | Lactic Acid - chemistry | Antineoplastic Agents, Phytogenic - chemistry | Mice, Inbred Strains | Paclitaxel - therapeutic use | Neoplasms - drug therapy | Surface-Active Agents - pharmacology | Particle Size | Animals | Polyglycolic Acid - chemistry | Survival Analysis | Excipients - pharmacology | Mice | HeLa Cells | Antineoplastic Agents, Phytogenic - pharmacology | Neoplasms - pathology | Drugs | Nanoparticles | Chemotherapy | Drug delivery systems | Nanotechnology | Cervical cancer | Cancer | Vehicles
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11. Full Text Biodegradable, Hydrogen Peroxide, and Glutathione Dual Responsive Nanoparticles for Potential Programmable Paclitaxel Release
by Chen, Daiqin and Zhang, Guoqiang and Li, Ruimin and Guan, Mirong and Wang, Xueyun and Zou, Toujun and Zhang, Ying and Wang, Chunru and Shu, Chunying and Hong, Hao and Wan, Li-Jun
Journal of the American Chemical Society, ISSN 0002-7863, 06/2018, Volume 140, Issue 24, pp. 7373 - 7376
Reactive oxygen species (ROS) and glutathione (GSH) dual responsive nanoparticulate drug delivery systems (nano-DDSs) hold great promise to improve the... 
POLYMERIC NANOPARTICLES | GENE DELIVERY | PRODRUG | DRUG-DELIVERY | SYNERGISTIC THERAPY | NANOMEDICINE | ALPHA-LIPOIC ACID | BIOMEDICAL APPLICATIONS | CHEMISTRY, MULTIDISCIPLINARY | CANCER-THERAPY | CHEMOTHERAPY | Paclitaxel - pharmacology | Cricetulus | Nanoparticles - chemistry | Humans | Sulfides - chemistry | Drug Carriers - toxicity | Male | Sulfides - chemical synthesis | Antineoplastic Agents - therapeutic use | Drug Carriers - chemistry | Hydrogen Peroxide - chemistry | Paclitaxel - chemistry | Sulfides - toxicity | Biodegradable Plastics - toxicity | Biodegradable Plastics - chemical synthesis | Antineoplastic Agents - pharmacology | Prostatic Neoplasms - drug therapy | CHO Cells | Polymers - chemical synthesis | Drug Carriers - chemical synthesis | Antineoplastic Agents - chemistry | Nanoparticles - toxicity | Paclitaxel - therapeutic use | Xenograft Model Antitumor Assays | Animals | Green Chemistry Technology - methods | Polymers - toxicity | Cell Line, Tumor | Drug Liberation | Polymers - chemistry | Glutathione - chemistry | Mice | Biodegradable Plastics - chemistry | Index Medicus
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12. Full Text A poly(ethylene glycol)-based surfactant for formulation of drug-loaded mucus penetrating particles
by Mert, Olcay and Lai, Samuel K and Ensign, Laura and Yang, Ming and Wang, Ying-Ying and Wood, Joseph and Hanes, Justin
Journal of Controlled Release, ISSN 0168-3659, 02/2012, Volume 157, Issue 3, pp. 455 - 460
Mucosal surfaces are protected by a highly viscoelastic and adhesive mucus layer that traps most foreign particles, including conventional drug and gene... 
Drug delivery | PEG | Mucin | Vitamin E TPGS | VITAMIN-E-TPGS | PACLITAXEL TAXOL(R) | BARRIER | CONTROLLED-RELEASE | POLY(VINYL ALCOHOL) | MICROPARTICLES | CHEMISTRY, MULTIDISCIPLINARY | DELIVERY | NANOPARTICLES | TRACKING | PHARMACOLOGY & PHARMACY | FABRICATION | Paclitaxel - chemistry | Lactic Acid - chemistry | Nanoparticles - chemistry | Humans | Polyglycolic Acid - chemistry | Antineoplastic Agents, Phytogenic - chemistry | Polyethylene Glycols - chemistry | Surface-Active Agents - chemistry | Vitamin E - chemistry | Cervix Mucus - chemistry | Chemistry, Pharmaceutical | Drug Carriers - chemistry | Drugs | Ethylene glycol | Drug delivery systems | Polyethylene | Surface active agents | Glycols | Nucleic acids | Vehicles | drug delivery | mucin
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13. Full Text Well‐Defined, Reversible Boronate Crosslinked Nanocarriers for Targeted Drug Delivery in Response to Acidic pH Values and cis‐Diols
by Li, Yuanpei and Xiao, Wenwu and Xiao, Kai and Berti, Lorenzo and Luo, Juntao and Tseng, Harry P and Fung, Gabriel and Lam, Kit S
Angewandte Chemie International Edition, ISSN 1433-7851, 03/2012, Volume 51, Issue 12, pp. 2864 - 2869
Demand and deliver: Micelles reversibly crosslinked by boronate esters (see scheme) show in vitro and in vivo stability, and thus minimize premature drug... 
boronate | controlled release | FRET | micelles | nanocarriers | NANOPARTICLES | PACLITAXEL DELIVERY | RELEASE | CHEMISTRY, MULTIDISCIPLINARY | Nanoparticles - chemistry | Humans | Catechols - chemistry | Boronic Acids - chemistry | Drug Carriers - chemistry | Neoplasms - drug therapy | Paclitaxel - chemistry | Micelles | Glucose - chemistry | Cell Line, Tumor | Fluorescence Resonance Energy Transfer | Mannitol - chemistry | Paclitaxel - administration & dosage | Hydrogen-Ion Concentration
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14. Full Text Biodegradation and Toxicity of Protease/Redox/pH Stimuli-Responsive PEGlated PMAA Nanohydrogels for Targeting Drug delivery
by Jin, Sha and Wan, Jiaxun and Meng, Lizheng and Huang, Xiaoxing and Guo, Jia and Liu, Li and Wang, Changchun
ACS Applied Materials & Interfaces, ISSN 1944-8244, 09/2015, Volume 7, Issue 35, pp. 19843 - 19852
The application of nanomaterials in intelligent drug delivery is developing rapidly for treatment of cancers. In this paper, we fabricated a new kind of... 
dual-drug loading | biodegradable | acute toxicity | surface modification | intravital fluorescence imaging | nanohydrogels | multi stimuli-responsive | THERAPEUTICS | MATERIALS SCIENCE, MULTIDISCIPLINARY | CONTROLLED-RELEASE | NANOSCIENCE & NANOTECHNOLOGY | CANCER | PACLITAXEL | NANOPARTICLES | THERAPY | CISPLATIN | GENE-TRANSFER | NANOGELS | dual-drug loading multi stimuli-responsive | LIPOSOMES | Paclitaxel - metabolism | Paclitaxel - pharmacology | Glutathione - metabolism | Humans | Polyethylene Glycols - chemistry | Doxorubicin - chemistry | Drug Carriers - chemistry | Antineoplastic Agents - metabolism | Paclitaxel - chemistry | Antineoplastic Agents - pharmacology | Doxorubicin - metabolism | Peptide Hydrolases - metabolism | Biodegradation, Environmental | Cell Survival - drug effects | Drug Carriers - metabolism | Oxidation-Reduction | Folic Acid - chemistry | Polymethacrylic Acids - chemistry | Antineoplastic Agents - chemistry | Mice, Inbred ICR | Animals | Drug Liberation | Nanostructures - chemistry | Glutathione - chemistry | Mice | HeLa Cells | Doxorubicin - pharmacology | Hydrogels - chemistry | Hydrogen-Ion Concentration | Index Medicus
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