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JAMA : the journal of the American Medical Association, ISSN 0098-7484, 03/2018, Volume 319, Issue 9, pp. 872 - 882
Journal Article
Neuron (Cambridge, Mass.), ISSN 0896-6273, 2011, Volume 70, Issue 3, pp. 482 - 494
Transient receptor potential melastatin-3 (TRPM3) is a broadly expressed Ca 2+-permeable nonselective cation channel. Previous work has demonstrated robust... 
TEMPERATURE | TRPV4 | CATION CHANNEL | ION-CHANNEL | PREGNENOLONE SULFATE | VANILLOID RECEPTOR-1 | COLD | CAPSAICIN-RECEPTOR | NEUROSCIENCES | MICE LACKING | EVOKED ACTIVATION | Hyperalgesia - chemically induced | Telemetry - methods | Calcium - metabolism | Capsaicin - pharmacology | Humans | Ganglia, Spinal - cytology | Transient Receptor Potential Channels - deficiency | Inflammation - metabolism | Time Factors | Behavior, Animal - drug effects | Sensory Receptor Cells - metabolism | Disease Models, Animal | Membrane Potentials - drug effects | Plant Oils - pharmacology | Trigeminal Ganglion - cytology | Mice, Knockout | Blood Glucose - drug effects | Patch-Clamp Techniques | Hyperalgesia - genetics | Transient Receptor Potential Channels - genetics | Gene Expression Regulation - radiation effects | TRPM Cation Channels - genetics | Blood Glucose - genetics | Mice | Inflammation - chemically induced | Mustard Plant | Pain Threshold - physiology | TRPM Cation Channels - deficiency | Membrane Potentials - genetics | Pregnenolone - adverse effects | Dose-Response Relationship, Drug | Transfection - methods | Bridged Bicyclo Compounds, Heterocyclic - therapeutic use | Freund's Adjuvant - adverse effects | Pain Threshold - drug effects | Nifedipine - pharmacology | Hot Temperature - adverse effects | Hyperalgesia - metabolism | Gene Expression Regulation - genetics | Mice, Inbred C57BL | Pain Measurement - drug effects | Calcium Channel Blockers - pharmacology | Pain Measurement - methods | Animals | Sensory Receptor Cells - drug effects | TRPM Cation Channels - antagonists & inhibitors | Hyperalgesia - drug therapy | TRPA1 Cation Channel | Inflammation - genetics | Acrylamides - therapeutic use | TRPM Cation Channels - metabolism | Cell Line, Transformed | Chemotherapy | Progesterone | Sulfates | Cancer | Heat | Behavior | Cold | Neurons | Rodents
Journal Article
Gastroenterology (New York, N.Y. 1943), ISSN 0016-5085, 2016, Volume 150, Issue 4, pp. 875 - 887.e9
Abstract Background & Aims Histamine sensitizes the nociceptor TRPV1 and has been shown to contribute to visceral hypersensitivity in animals. We investigated... 
Gastroenterology and Hepatology | Sensory Neurons | Drug | Transient Receptor Potential Cation Channel Subfamily V Member 1 | Treatment | PROTEIN-KINASE-C | LINACLOTIDE | COLONIC HYPERSENSITIVITY | DISORDERS | MUTATIONAL ANALYSIS | POTENTIAL VANILLOID 1 | CLINICAL-TRIALS | BINDING-SITE | PLACEBO-CONTROLLED TRIAL | ION CHANNELS | GASTROENTEROLOGY & HEPATOLOGY | Abdominal Pain - prevention & control | Humans | Middle Aged | Male | Young Adult | Receptors, Histamine H1 - drug effects | TRPV Cation Channels - metabolism | Receptors, Histamine H1 - metabolism | Time Factors | Irritable Bowel Syndrome - diagnosis | Rectum - innervation | Pain Threshold - drug effects | Adult | Female | Surveys and Questionnaires | Neurons - metabolism | Neurons - drug effects | Analgesics - adverse effects | Analgesics - therapeutic use | Irritable Bowel Syndrome - metabolism | Butyrophenones - therapeutic use | Double-Blind Method | Abdominal Pain - physiopathology | Irritable Bowel Syndrome - drug therapy | Treatment Outcome | Abdominal Pain - metabolism | Irritable Bowel Syndrome - physiopathology | Remission Induction | Butyrophenones - adverse effects | Histamine H1 Antagonists - adverse effects | Belgium | Histamine H1 Antagonists - therapeutic use | Biopsy | Calcium Signaling - drug effects | Piperidines - therapeutic use | Piperidines - adverse effects | Adolescent | Gastrointestinal Agents - therapeutic use | Quality of Life | Aged | Gastrointestinal Agents - adverse effects | Pain Measurement | Receptor Cross-Talk - drug effects | Drugs | Histamine | Care and treatment | Drug delivery systems | Gastrointestinal diseases | Irritable bowel syndrome | Research institutes | Vehicles
Journal Article
Journal Article
Nature neuroscience, ISSN 1546-1726, 2010, Volume 13, Issue 10, pp. 1265 - 1270
Peripheral cannabinoid receptors exert a powerful inhibitory control over pain initiation, but the endocannabinoid signal that normally engages this intrinsic... 
CANNABINOID RECEPTORS | SYSTEM | CB2 RECEPTORS | LOCALIZATION | FAAH | ACTIVATION | ACID AMIDE HYDROLASE | INHIBITORS | NEUROSCIENCES | RAT MODEL | ANALGESIA | Cannabinoid Receptor Modulators - metabolism | Pyrazoles - therapeutic use | Male | Sciatica - drug therapy | Monoacylglycerol Lipases - metabolism | Arachidonic Acids - metabolism | Cannabinoid Receptor Modulators - therapeutic use | Pain - genetics | Time Factors | Statistics, Nonparametric | Escape Reaction - drug effects | Amidohydrolases - deficiency | Endocannabinoids | Disease Models, Animal | Drug Administration Routes | Rats | Pain - pathology | Rats, Sprague-Dawley | Cannabinoids - pharmacology | Mice, Knockout | Ethylene Glycols - metabolism | Cannabinoids - therapeutic use | Arachidonic Acids - therapeutic use | Hyperalgesia - genetics | Indoles - therapeutic use | Mice | Carrageenan | Enzyme Inhibitors | Spinal Cord - metabolism | Polyunsaturated Alkamides - therapeutic use | Motor Activity - drug effects | Tritium | Pain - chemically induced | Formaldehyde | Pain Threshold - drug effects | Amidohydrolases - metabolism | Oncogene Proteins v-fos - metabolism | Tissue Distribution - drug effects | Drug Administration Schedule | Pain - prevention & control | Gene Expression Regulation - genetics | Mice, Inbred C57BL | Pain Measurement - drug effects | Polyunsaturated Alkamides - metabolism | Feeding Behavior - drug effects | Gene Expression Regulation - drug effects | PPAR alpha - deficiency | Animals | Hyperalgesia - drug therapy | Peripheral Nervous System Diseases | Piperidines - therapeutic use | Cannabinoid Receptor Modulators - antagonists & inhibitors | Chromatography, Liquid - methods | Mass Spectrometry - methods | Cannabinoids | Care and treatment | Pain | Analgesics | Evoked potentials (Electrophysiology) | Physiological aspects | Dosage and administration | Research | Methods
Journal Article
European Neuropsychopharmacology, ISSN 0924-977X, 2013, Volume 24, Issue 4, pp. 608 - 620
.... In this study, we have investigated the analgesic effects of BCP in animal models of inflammatory and neuropathic pain... 
Internal Medicine | Psychiatry | Beta-caryophyllene | CB2 | Dietary cannabinoid | Inflammatory pain | Neuropathic pain | CELLS | ACTIVATION | PSYCHIATRY | ESSENTIAL OIL | INVOLVEMENT | ANANDAMIDE | MECHANISMS | NEUROSCIENCES | CLINICAL NEUROLOGY | RESPONSES | MULTIPLE-SCLEROSIS | PHARMACOLOGY & PHARMACY | MICE | CONSTITUENTS | Phytochemicals - therapeutic use | Spinal Cord - drug effects | Spinal Cord - metabolism | Receptor, Cannabinoid, CB2 - agonists | Neuralgia - metabolism | Motor Activity - drug effects | Male | Sesquiterpenes - administration & dosage | Receptor, Cannabinoid, CB2 - genetics | Phytochemicals - adverse effects | Sesquiterpenes - adverse effects | Sesquiterpenes - therapeutic use | Sciatic Nerve - immunology | Neuralgia - immunology | Sciatic Nerve - metabolism | Cannabinoid Receptor Agonists - adverse effects | Cannabinoid Receptor Agonists - therapeutic use | Behavior, Animal - drug effects | Neurons - metabolism | Sciatic Nerve - drug effects | Neurons - drug effects | Sciatic Neuropathy - drug therapy | Disease Models, Animal | Phytochemicals - administration & dosage | Sciatic Neuropathy - immunology | Hyperalgesia - metabolism | Administration, Oral | Nerve Tissue Proteins - agonists | Neurons - immunology | Cannabinoid Receptor Agonists - administration & dosage | Nerve Tissue Proteins - genetics | Neuralgia - drug therapy | Gene Expression Regulation - drug effects | Nerve Tissue Proteins - metabolism | Spinal Cord - immunology | Hyperalgesia - immunology | Receptor, Cannabinoid, CB2 - metabolism | Animals | Anti-Inflammatory Agents, Non-Steroidal - adverse effects | Hyperalgesia - drug therapy | Anti-Inflammatory Agents, Non-Steroidal - therapeutic use | Anti-Inflammatory Agents, Non-Steroidal - administration & dosage | Mice | Mice, Congenic | Pain Measurement | Sciatic Neuropathy - metabolism
Journal Article
American Journal of Health-System Pharmacy, ISSN 1079-2082, 11/2017, Volume 74, Issue 22, pp. 1865 - 1877
Journal Article
Cochrane library, ISSN 1465-1858, 2013, Volume 2019, Issue 1, p. CD006146
Journal Article