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Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 12/2012, Volume 109, Issue 50, pp. 20709 - 20713
Relief of pain is rewarding. Using a model of experimental postsurgical pain we show that blockade of afferent input from the injury with local anesthetic... 
Dopaminergic neurons | Nucleus accumbens | Pain | Catheterization | Neurons | Rats | Midbrain | Physical trauma | Behavioral neuroscience | Ventral tegmental area | Immunohistochemistry | Incision | In vivo microdialysis | Motivated behavior | motivated behavior | RAT | MORPHINE | CONDITIONED PLACE PREFERENCE | A10 DOPAMINE NEURONS | NOXIOUS STIMULI | FOS EXPRESSION | MULTIDISCIPLINARY SCIENCES | NUCLEUS-ACCUMBENS | ONGOING PAIN | ventral tegmental area | incision | immunohistochemistry | in vivo microdialysis | MODULATION | Pain, Postoperative - drug therapy | Nerve Block | Afferent Pathways - physiopathology | Male | Dopamine Antagonists - administration & dosage | Pain - drug therapy | Limbic System - physiopathology | Afferent Pathways - drug effects | Anesthetics, Local - administration & dosage | Disease Models, Animal | Limbic System - drug effects | Nucleus Accumbens - physiopathology | Ventral Tegmental Area - drug effects | Pain, Postoperative - psychology | Ventral Tegmental Area - physiopathology | Reinforcement (Psychology) | Rats, Sprague-Dawley | Pain - psychology | Animals | Pain - physiopathology | Models, Neurological | Reward | Nucleus Accumbens - drug effects | Pain, Postoperative - physiopathology | Psychological aspects | Care and treatment | Neural circuitry | Physiological aspects | Limbic system | Health aspects | Brain | Postoperative period | Dopamine | Surgery | Pain management | Index Medicus | Biological Sciences
Journal Article
Journal Article