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Development, ISSN 0950-1991, 01/2010, Volume 137, Issue 2, pp. 203 - 212
The transcription factor neurogenin 3 (Neurog3 or Ngn3) controls islet cell fate specification in multipotent pancreatic progenitor cells in the mouse embryo.... 
Mouse | Rfx | Endocrine | Zebrafish | Cell differentiation | Pancreas | Transcription factor | Neurogenin 3 | PROGENITOR CELLS | NEUROGENIN3 | BETA-CELLS | DEVELOPMENTAL BIOLOGY | HORMONE-EXPRESSING CELLS | PROTEIN ISL-1 | ENDOCRINE PANCREAS | GENE | EMBRYONIC STEM-CELLS | DIFFERENTIATION | Immunohistochemistry | Paired Box Transcription Factors - genetics | Homeodomain Proteins - metabolism | Pancreas - cytology | Winged-Helix Transcription Factors - metabolism | Embryo, Nonmammalian - metabolism | Stem Cells - cytology | Stem Cells - metabolism | Embryo, Mammalian - metabolism | Endocrine Cells - metabolism | In Situ Hybridization | Basic Helix-Loop-Helix Transcription Factors - metabolism | Gene Expression Regulation, Developmental | Islets of Langerhans - metabolism | Islets of Langerhans - cytology | Somatostatin - metabolism | Basic Helix-Loop-Helix Transcription Factors - genetics | Zebrafish Proteins - metabolism | Winged-Helix Transcription Factors - genetics | Cells, Cultured | Pancreas - metabolism | Transcription Factors - genetics | Reverse Transcriptase Polymerase Chain Reaction | Nerve Tissue Proteins - genetics | Pancreas - embryology | Homeodomain Proteins - genetics | Endoderm - metabolism | Ghrelin - metabolism | Nerve Tissue Proteins - metabolism | Transcription Factors - metabolism | Blotting, Northern | Animals | Endocrine Cells - cytology | Glucagon - metabolism | Mice | Zebrafish Proteins - genetics | In Vitro Techniques | Paired Box Transcription Factors - metabolism | Index Medicus | Development and Stem Cells
Journal Article
Nature Structural and Molecular Biology, ISSN 1545-9993, 10/2012, Volume 19, Issue 10, pp. 1023 - 1032
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 1/2010, Volume 107, Issue 1, pp. 40 - 45
Although cancer is a disease with genetic and epigenetic origins, the possible effects of reprogramming by defined factors remain to be fully understood. We... 
Neurons | Induced pluripotent stem cells | Epithelial cells | Stem cells | Cell lines | Adipocytes | Pluripotent stem cells | Embryonic stem cells | Cellular differentiation | Cells | Epigenetics | Cancer stem cells | Differentiation | PLURIPOTENT STEM-CELLS | differentiation | pluripotent stem cells | embryonic stem cells | MULTIDISCIPLINARY SCIENCES | NANOG | cancer stem cells | IDENTIFICATION | epigenetics | LINES | Paired Box Transcription Factors - genetics | Neoplastic Stem Cells - cytology | Gastrointestinal Neoplasms - genetics | Neoplastic Stem Cells - drug effects | Epigenesis, Genetic | Homeodomain Proteins - metabolism | Humans | SOXB1 Transcription Factors - metabolism | DNA (Cytosine-5-)-Methyltransferases - metabolism | Octamer Transcription Factor-3 - genetics | Gastrointestinal Neoplasms - pathology | DNA Methylation | Retroviridae - genetics | SOXB1 Transcription Factors - genetics | Lentivirus - genetics | Antineoplastic Agents - pharmacology | Eye Proteins - genetics | Cell Differentiation - physiology | Neoplastic Stem Cells - physiology | Repressor Proteins - metabolism | Gastrointestinal Neoplasms - metabolism | Biomarkers - metabolism | Nanog Homeobox Protein | Pluripotent Stem Cells - cytology | Pluripotent Stem Cells - physiology | Repressor Proteins - genetics | PAX6 Transcription Factor | Mice, SCID | Homeodomain Proteins - genetics | DNA (Cytosine-5-)-Methyltransferases - genetics | Animals | Eye Proteins - metabolism | Cell Differentiation - drug effects | Octamer Transcription Factor-3 - metabolism | Pluripotent Stem Cells - drug effects | Cell Line, Tumor | Mice, Inbred NOD | Mice | Paired Box Transcription Factors - metabolism | Epigenetic inheritance | Care and treatment | Gastrointestinal cancer | Physiological aspects | Genetic aspects | Research | Proteins | Gene expression | Rodents | Deoxyribonucleic acid--DNA | Cancer | Index Medicus | Biological Sciences
Journal Article
Developmental Cell, ISSN 1534-5807, 05/2013, Volume 25, Issue 3, pp. 256 - 269
Journal Article
Nature, ISSN 0028-0836, 2014, Volume 511, Issue 7509, pp. 358 - 361
Journal Article
Journal Article
Human Molecular Genetics, ISSN 0964-6906, 2/2008, Volume 17, Issue 4, pp. 478 - 489
We previously demonstrated that the transcription factor Pax4 is important for β-cell replication and survival in rat islets. Herein, we investigate Pax4... 
APOPTOSIS | REPLICATION | GLUCAGON-LIKE PEPTIDE-1 | REGENERATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | GENETICS & HEREDITY | GENE-EXPRESSION | PDX1 | FATTY-ACIDS | DIFFERENTIATION | DYSFUNCTION | BETA-CELL PROLIFERATION | Paired Box Transcription Factors - genetics | Islets of Langerhans - drug effects | Mitogens - pharmacology | Diabetes Mellitus, Type 2 - genetics | Epigenesis, Genetic | Homeodomain Proteins - metabolism | Humans | Diabetes Mellitus, Type 2 - metabolism | Interleukin-1beta - genetics | RNA, Messenger - metabolism | Obesity - genetics | Insulin-Secreting Cells - metabolism | Transfection | Islets of Langerhans - metabolism | fas Receptor - genetics | Insulin-Secreting Cells - cytology | Insulin Secretion | Diabetes Mellitus, Type 2 - complications | Gene Expression | Signal Transduction | Obesity - complications | RNA, Messenger - genetics | Glucagon-Like Peptide 1 - pharmacology | Rats | Glucose - pharmacology | Homeodomain Proteins - genetics | Obesity - metabolism | Insulin - metabolism | Animals | Activins - pharmacology | Betacellulin | Insulin-Secreting Cells - drug effects | Intercellular Signaling Peptides and Proteins - pharmacology | Cell Proliferation - drug effects | In Vitro Techniques | Paired Box Transcription Factors - metabolism | Index Medicus | Glucagon-Like Peptide 1 | Cell Proliferation | Activins | Glucose | Antigens, CD95 | Life Sciences | Endocrinology and metabolism | Diabetes Mellitus, Type 2 | Insulin-Secreting Cells | Obesity | Paired Box Transcription Factors | Intercellular Signaling Peptides and Proteins | Interleukin-1beta | Insulin | Human health and pathology | Homeodomain Proteins | Islets of Langerhans | Mitogens | RNA, Messenger
Journal Article
Journal Article
Developmental Biology, ISSN 0012-1606, 2005, Volume 286, Issue 1, pp. 217 - 224
Recently, the expression of the peptide hormone ghrelin was detected in α-cells of the islets of Langerhans as well as in ε-cells, a newly discovered endocrine... 
Glucagon | Ghrelin | Arx | Neurogenin3 | Pax4 | Development | Endocrine | Pax6 | Pancreas | HOMEODOMAIN TRANSCRIPTION FACTOR | development | ALPHA-CELLS | MOUSE PANCREAS | BETA-CELLS | INSULIN-SECRETION | ISLET-CELL | DEVELOPMENTAL BIOLOGY | ghrelin | HORMONE | pancreas | glucagon | DIFFERENTIATION | neurogenin3 | endocrine | Paired Box Transcription Factors - genetics | Paired Box Transcription Factors - deficiency | Homeodomain Proteins - metabolism | Nerve Tissue Proteins - deficiency | Transcription Factors - deficiency | Green Fluorescent Proteins - genetics | Peptide Hormones - genetics | Peptide Hormones - metabolism | Basic Helix-Loop-Helix Transcription Factors - metabolism | Gene Expression Regulation, Developmental | Islets of Langerhans - metabolism | Mice, Mutant Strains | Islets of Langerhans - cytology | Eye Proteins - genetics | Basic Helix-Loop-Helix Transcription Factors - deficiency | Repressor Proteins - metabolism | Recombinant Proteins - metabolism | Green Fluorescent Proteins - metabolism | Basic Helix-Loop-Helix Transcription Factors - genetics | Repressor Proteins - genetics | Mice, Transgenic | PAX6 Transcription Factor | Recombinant Proteins - genetics | Transcription Factors - genetics | Nerve Tissue Proteins - genetics | Homeodomain Proteins - genetics | Nerve Tissue Proteins - metabolism | Transcription Factors - metabolism | Animals | Eye Proteins - metabolism | Glucagon - metabolism | Islets of Langerhans - growth & development | Mice | Paired Box Transcription Factors - metabolism | Index Medicus | Green Fluorescent Proteins | Paired Box Transcription Factors | Repressor Proteins | Biochemistry, Molecular Biology | Nerve Tissue Proteins | Recombinant Proteins | Life Sciences | Peptide Hormones | Homeodomain Proteins | Transcription Factors | Islets of Langerhans | Molecular biology | Eye Proteins | Basic Helix-Loop-Helix Transcription Factors
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 1/2011, Volume 108, Issue 1, pp. 155 - 160
The neural crest (NC) emerges from combinatorial inductive events occurring within its progenitor domain, the neural border (NB). Several transcription factors... 
Vertebrates | Up regulation | Ectoderm | Transcription factors | Messenger RNA | Neurons | Government regulation | Evolution | Embryos | Neural crest | Pax3 | Msx1 | Xenopus embryo | Hairy2 | Zic1 | MULTIDISCIPLINARY SCIENCES | SIGNALS | FIBROBLAST-GROWTH-FACTOR | INDUCTION | SPECIFICATION | TRANSCRIPTION FACTOR AP-2 | XENOPUS-LAEVIS | EVOLUTION | ECTODERM | EXPRESSION | EMBRYOS | Paired Box Transcription Factors - genetics | PAX3 Transcription Factor | Gene Regulatory Networks - genetics | Xenopus laevis - embryology | Xenopus Proteins - genetics | Humans | Gene Expression Regulation, Developmental - genetics | Transcription Factors - genetics | Reverse Transcriptase Polymerase Chain Reaction | Transcription Factor AP-2 - metabolism | Gene Knockdown Techniques | Neural Crest - metabolism | Transcription Factors - metabolism | Transcription Factor AP-2 - genetics | Animals | Epistasis, Genetic | Models, Biological | Neural Crest - embryology | Xenopus Proteins - metabolism | Electrophoretic Mobility Shift Assay | Paired Box Transcription Factors - metabolism | Gene Expression Regulation, Developmental - physiology | Genetic aspects | Neural circuitry | Gene expression | Health aspects | Analysis | Cellular biology | Genes | Index Medicus | Paired Box Transcription Factors | Xenopus laevis | Neurons and Cognition | Psychology and behavior | Neurobiology | Xenopus Proteins | Transcription Factor AP-2 | Gene Regulatory Networks | Neural Crest | Life Sciences | Gene Expression Regulation, Developmental | Cognitive Sciences | Transcription Factors | Biological Sciences
Journal Article
The Journal of Cell Biology, ISSN 0021-9525, 9/2010, Volume 190, Issue 5, pp. 867 - 879
Skeletal muscle satellite cells are adult stem cells responsible for postnatal skeletal muscle growth and regeneration. Paired-box transcription factor Pax7... 
Skeletal muscle satellite cells | Artificial satellites | Cell growth | MicroRNA | Stem cells | Cell lines | Muscles | Cellular differentiation | Skeletal muscle | Myoblasts | PROGENITOR CELLS | RNA INTERFERENCE | MYOGENESIS | REGENERATION | EMBRYONIC STEM-CELLS | HEART-FAILURE | SELF-RENEWAL | FATE DETERMINATION | EXPRESSION | PROGRESSION | CELL BIOLOGY | Paired Box Transcription Factors - genetics | Up-Regulation | Cell Proliferation | MicroRNAs - metabolism | PAX7 Transcription Factor - metabolism | Stem Cells - cytology | Muscle, Skeletal - cytology | Stem Cells - metabolism | Cell Differentiation - genetics | Myoblasts - metabolism | Regeneration - genetics | Satellite Cells, Skeletal Muscle - physiology | Cell Differentiation - physiology | Cell Line | Muscle, Skeletal - growth & development | PAX7 Transcription Factor - physiology | Muscle Development - physiology | Satellite Cells, Skeletal Muscle - cytology | Cells, Cultured | Satellite Cells, Skeletal Muscle - metabolism | Muscle, Skeletal - physiology | Regeneration - physiology | Proteins - genetics | Animals | Proteins - metabolism | Muscle Development - genetics | Mice | MicroRNAs - genetics | Paired Box Transcription Factors - metabolism | Muscle cells | Research | RNA | Studies | Proteins | Musculoskeletal system | Survival analysis | Genes | Cells | Index Medicus
Journal Article
Nature, ISSN 0028-0836, 11/2012, Volume 491, Issue 7422, pp. 66 - 71
Journal Article