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Archives of Oral Biology, ISSN 0003-9969, 2011, Volume 56, Issue 7, pp. 650 - 654
Abstract Objectives This study assessed the antibacterial activity of short-, medium-, and long-chain fatty acids against various oral microorganisms. Methods... 
Advanced Basic Science | Dentistry | Medium-chain | Antimicrobial activity | Long-chain fatty acids | Bacterial ecology | Short-chain | STREPTOCOCCUS-MUTANS | BACTERIA | PORPHYROMONAS-GINGIVALIS | MECHANISMS | PERIODONTAL-DISEASE | DENTAL BIOFILM | REACTIVATION | DENTISTRY, ORAL SURGERY & MEDICINE | INFECTION | Fatty Acids, Volatile - pharmacology | Propionates - pharmacology | Palmitic Acid - pharmacology | Anti-Infective Agents - pharmacology | Caproates - pharmacology | Humans | Caprylates - pharmacology | Fusobacterium nucleatum - drug effects | Lauric Acids - pharmacology | Candida albicans - drug effects | Streptococcus sanguis - drug effects | Pentanoic Acids - pharmacology | Butyric Acid - pharmacology | Streptococcus gordonii - drug effects | Aggregatibacter actinomycetemcomitans - drug effects | Biofilms - drug effects | Myristic Acid - pharmacology | Decanoic Acids - pharmacology | Acetic Acid - pharmacology | Isobutyrates - pharmacology | Materials Testing | Streptococcus mutans - drug effects | Microbial Interactions - drug effects | Mouth - microbiology | Formates - pharmacology | Fatty Acids - pharmacology | Porphyromonas gingivalis - drug effects | Lauric acid | Propionic acid | Data processing | Palmitic acid | Fatty acids | Butyric acid | Oral cavity | octanoic acid | Microorganisms | Biofilms | Formic acid | Antibacterial activity | Evolution | Acetic acid
Journal Article
PLoS ONE, ISSN 1932-6203, 2011, Volume 6, Issue 8, p. e23183
Elevated concentrations of serum non-esterified fatty acids (NEFA), associated with maternal disorders such as obesity and type II diabetes, alter the ovarian... 
IN-VITRO | OBESITY | INFERTILE WOMEN | METABOLISM | GLUCOSE-TRANSPORTER | MULTIDISCIPLINARY SCIENCES | PREIMPLANTATION DEVELOPMENT | STEARIC-ACID | BODY-MASS INDEX | PALMITIC ACID | INDUCE APOPTOSIS | Palmitic Acid - pharmacology | Apoptosis - drug effects | Cell Count | Zygote - metabolism | Blastocyst - physiology | Male | Fatty Acids, Nonesterified - pharmacology | Oxygen - metabolism | Receptor, IGF Type 2 - genetics | Amino Acids - metabolism | Oocytes - cytology | Oleic Acid - pharmacology | Palmitic Acid - blood | Cattle | Oleic Acid - blood | Pyruvic Acid - metabolism | Fatty Acids, Nonesterified - blood | Female | Zygote - cytology | Oocytes - metabolism | Blastocyst - metabolism | Gene Expression Regulation, Developmental - drug effects | Blastocyst - cytology | Reverse Transcriptase Polymerase Chain Reaction | DNA (Cytosine-5-)-Methyltransferases - genetics | Animals | Lactates - metabolism | Oocytes - physiology | Glucose Transporter Type 1 - genetics | Stearic Acids - blood | Glucose - metabolism | Zygote - physiology | Stearic Acids - pharmacology | Lactates | Obesity | Embryonic development | Embryo | Methyltransferases | RNA | Genes | Amino acids | Fatty acids | Apoptosis | Laboratories | Oxidative metabolism | Pyruvic acid | mRNA | Biochemistry | Oocytes | Insulin-like growth factor II receptors | Fertility | Quality | DNA methylation | Physiology | Carbohydrates | Maturation | Diabetes mellitus | Oxygen consumption | Blastocysts | Gene expression | Metabolism | Embryos | Esterification | Zygotes | Cell number | Insulin resistance | Hypoxia | Reproductive technologies | Diabetes | Lactic acid | Miscarriage | Viability | Metabolic disorders | Pharmaceuticals
Journal Article
Journal of Neurochemistry, ISSN 0022-3042, 03/2012, Volume 120, Issue 6, pp. 1060 - 1071
J. Neurochem. (2012) 120, 1060–1071. This study describes the effects of long‐chain fatty acids on inflammatory signaling in cultured astrocytes. Data show... 
brain inflammation | cytokines | reactive gliosis | dyslipidemia | obesity | Reactive gliosis | Obesity | Cytokines | Brain inflammation | Dyslipidemia | 3T3-L1 ADIPOCYTES | OXIDATIVE STRESS | ALZHEIMERS-DISEASE | BIOCHEMISTRY & MOLECULAR BIOLOGY | DIET-INDUCED OBESITY | NEUROSCIENCES | COGNITIVE FUNCTION | INDUCED INSULIN-RESISTANCE | TERM POTENTIATION | ENDOTHELIAL-CELLS | TNF-ALPHA | NEURONAL PLASTICITY | Animals, Newborn | Astrocytes - drug effects | Brain - cytology | Palmitic Acid - pharmacology | Cytokines - metabolism | Enzyme-Linked Immunosorbent Assay | Cells, Cultured | Enzyme Inhibitors - pharmacology | Rats | Male | Toll-Like Receptor 2 - metabolism | Rats, Sprague-Dawley | Toll-Like Receptor 4 - metabolism | Dose-Response Relationship, Drug | Gene Expression Regulation - drug effects | Oleic Acid - pharmacology | Animals | Drug Interactions | Signal Transduction - drug effects | Female | Fatty Acids - metabolism | Fatty Acids - pharmacology | Unsaturated fatty acids | Inflammation | Saturated fatty acids | Fatty acids | Omega-3 fatty acids | Neurochemistry | Signal transduction | Brain | Cells | Astrocytes | Data processing | MAP kinase | CD36 antigen | Docosahexaenoic acid | Palmitic acid | Microglia | Gliosis | c-Jun amino-terminal kinase | Toll-like receptors | Stearic acid | Metabolic disorders | Tumor necrosis factor- alpha
Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 05/2012, Volume 7, Issue 5, p. e36663
Journal Article
Atherosclerosis, ISSN 0021-9150, 2008, Volume 202, Issue 2, pp. 382 - 393
Abstract Increased circulating free fatty acids in subjects with type 2 diabetes may contribute to activation of macrophages, and thus the development of... 
Cardiovascular | Serine palmitoyltransferase | Palmitate | Atherosclerosis | Stearate | Ceramide | Diabetes | Proinflammatory cytokines | Macrophages | INDUCED INSULIN-RESISTANCE | SIGNAL-TRANSDUCTION | DIABETES-MELLITUS | TOLL-LIKE RECEPTOR-2 | TUMOR-NECROSIS-FACTOR | INTERLEUKIN-6 EXPRESSION | FACTOR-ALPHA PROMOTER | GENE-EXPRESSION | PERIPHERAL VASCULAR DISEASE | NF-KAPPA-B | Tumor Necrosis Factor-alpha - metabolism | Interleukin-8 - genetics | Palmitic Acid - pharmacology | Monocytes - cytology | Humans | Leukemia | Tumor Necrosis Factor-alpha - genetics | JNK Mitogen-Activated Protein Kinases - metabolism | Interleukin-1beta - genetics | RNA, Messenger - metabolism | Lauric Acids - pharmacology | Transcription Factor AP-1 - metabolism | Ceramides - biosynthesis | Interleukin-1beta - metabolism | Interleukin-8 - secretion | p38 Mitogen-Activated Protein Kinases - metabolism | Interleukin-8 - metabolism | Linoleic Acid - pharmacology | Monocytes - physiology | Cytokines - genetics | Interleukin-1beta - secretion | Cytokines - metabolism | Myristic Acid - pharmacology | Tumor Necrosis Factor-alpha - secretion | Cytokines - secretion | Myeloid Differentiation Factor 88 - genetics | Palmitoyl Coenzyme A - metabolism | Monocytes - drug effects | Cell Line, Tumor | RNA, Small Interfering | Myeloid Differentiation Factor 88 - metabolism | Stearic Acids - pharmacology | Fatty Acids - pharmacology | Type 2 diabetes | Phorbol esters | Cytokines | RNA | Analysis | Development and progression | Mitogens | Saturated fatty acids | Phosphotransferases | cytology | Fatty Acids | Dermatologi och venereologi | Dermatology and Venereal Diseases | Mikrobiologi inom det medicinska området | Interleukin-8 | Transcription Factor AP-1 | Lauric Acids | genetics | biosynthesis | pharmacology | Ceramides | JNK Mitogen-Activated Protein Kinases | Tumor | Palmitic Acid | Palmitoyl Coenzyme A | p38 Mitogen-Activated Protein Kinases | Cell Line | Myristic Acid | Small Interfering | Stearic Acids | physiology | drug effects | Interleukin-1beta | Myeloid Differentiation Factor 88 | Messenger | Tumor Necrosis Factor-alpha | Monocytes | secretion | Microbiology in the medical area | Linoleic Acid | metabolism
Journal Article
British Journal of Pharmacology, ISSN 0007-1188, 06/2017, Volume 174, Issue 11, pp. 1349 - 1365
Palmitoylethanolamide (PEA) has emerged as a potential nutraceutical, because this compound is naturally produced in many plant and animal food sources, as... 
ALLERGIC CONTACT-DERMATITIS | NEUROPATHIC PAIN | PPAR-ALPHA | ACTIVATED-RECEPTOR-ALPHA | ENDOCANNABINOID-RELATED MOLECULES | CONCISE GUIDE | FATTY-ACID AMIDE | PHARMACOLOGY & PHARMACY | CENTRAL-NERVOUS-SYSTEM | CANNABINOID CB2 RECEPTOR | N-PALMITOYL-ETHANOLAMINE | Neurodegenerative Diseases - diet therapy | Analgesics - pharmacology | Ethanolamines - pharmacology | Ethanolamines - adverse effects | Palmitic Acids - adverse effects | Chemistry, Pharmaceutical - methods | Anti-Inflammatory Agents - pharmacology | Humans | Analgesics - administration & dosage | Ethanolamines - administration & dosage | Palmitic Acids - administration & dosage | Particle Size | Inflammation - diet therapy | Animals | Anti-Inflammatory Agents - adverse effects | Neuroprotective Agents - pharmacology | Anti-Inflammatory Agents - administration & dosage | Neuroprotective Agents - adverse effects | Palmitic Acids - pharmacology | Neuroprotective Agents - administration & dosage | Dietary Supplements | Analgesics - adverse effects | Flavonoids | Nervous system diseases | Pharmacology | Flavones | Health aspects | Bioflavonoids | Peripheral nervous system | Neuroprotection | Food plants | Particle size | Pain perception | Food sources | Neurodegenerative diseases | Palmitoylethanolamide | Nervous system | Inflammatory diseases | Antioxidants | Reviews | Nutraceuticals | Themed Section | Review
Journal Article
Journal of Neuroscience, ISSN 0270-6474, 12/2008, Volume 28, Issue 51, pp. 13985 - 13994
Nicotine stimulates the activity of mesolimbic dopamine neurons, which is believed to mediate the rewarding and addictive properties of tobacco use.... 
Peroxisome proliferator-activated receptor | Electrophysiology | Fatty acid amide hydrolase | Patch clamp | Dopamine neurons | Endocannabinoids | Nicotine | PPAR-ALPHA | nicotine | patch clamp | ANANDAMIDE HYDROLYSIS | NEUROSCIENCES | MOUSE THALAMIC SYNAPTOSOMES | VENTRAL TEGMENTAL AREA | AMIDE HYDROLASE | dopamine neurons | ACETYLCHOLINE-RECEPTORS | fatty acid amide hydrolase | ESTER URB597 | electrophysiology | CORTICAL-NEURONS | endocannabinoids | INFLAMMATORY PAIN | peroxisome proliferator-activated receptor | CB1 RECEPTORS | PPAR alpha - drug effects | Cannabinoid Receptor Antagonists | Protein-Tyrosine Kinases - metabolism | Injections, Intraventricular | Male | Ventral Tegmental Area - cytology | Nicotine - pharmacology | Receptors, Cannabinoid - metabolism | Piperidines - pharmacology | Benzamides - pharmacology | Neurons - metabolism | Oleic Acids - pharmacology | Palmitic Acids - pharmacology | Neurons - drug effects | Dopamine - metabolism | Organ Culture Techniques | Carbamates - pharmacology | Pyrazoles - pharmacology | Amidohydrolases - metabolism | Ventral Tegmental Area - drug effects | Appetite Depressants - pharmacology | Enzyme Inhibitors - pharmacology | Rats | Amidohydrolases - antagonists & inhibitors | Enzyme Activation - drug effects | Ethanolamines | Nicotine - antagonists & inhibitors | Rats, Sprague-Dawley | Arachidonic Acids - pharmacology | Patch-Clamp Techniques | Animals | Rimonabant | Ventral Tegmental Area - metabolism | PPAR alpha - metabolism | Lipoxygenase Inhibitors - pharmacology
Journal Article
Nature Medicine, ISSN 1078-8956, 08/2012, Volume 18, Issue 8, pp. 1232 - 1238
Primary astrocytomas of grade 3 or 4 according to the classification system of the World Health Organization (high-grade astrocytomas or HGAs) are preponderant... 
MEDICINE, RESEARCH & EXPERIMENTAL | STEM-CELLS | ADULT NEUROGENESIS | BIOCHEMISTRY & MOLECULAR BIOLOGY | ENDOPLASMIC-RETICULUM STRESS | MICE LACKING | CELL BIOLOGY | CANNABINOID RECEPTORS | GLIOBLASTOMA | ACID AMIDE HYDROLASE | IN-VIVO | VANILLOID RECEPTOR TRPV1 | GLIAL PROGENITORS | Endocannabinoids - pharmacology | Capsaicin - pharmacology | Capsaicin - therapeutic use | Humans | Male | Antineoplastic Agents - therapeutic use | Brain - metabolism | Oleic Acids - metabolism | Arachidonic Acids - metabolism | TRPV Cation Channels - biosynthesis | Glioblastoma - metabolism | Amidohydrolases - deficiency | Palmitic Acids - pharmacology | Neoplasm Proteins - genetics | Real-Time Polymerase Chain Reaction | Dopamine - metabolism | Tumor Cells, Cultured - drug effects | Capsaicin - analogs & derivatives | Brain Neoplasms - drug therapy | Mice, Knockout | Glioblastoma - pathology | Polyunsaturated Alkamides - pharmacology | Mice | Glioblastoma - drug therapy | Aging - metabolism | Cell Movement | Endocannabinoids - metabolism | Ethanolamines - pharmacology | TRPV Cation Channels - analysis | Neoplasm Proteins - physiology | Brain Neoplasms - pathology | Gene Expression Regulation, Neoplastic | Culture Media, Conditioned - pharmacology | Brain - growth & development | Brain Neoplasms - metabolism | Tumor Cells, Cultured - pathology | Female | Oleic Acids - pharmacology | TRPV Cation Channels - physiology | Neoplasm Proteins - biosynthesis | Amidohydrolases - genetics | Mice, Inbred C57BL | RNA, Small Interfering - pharmacology | TRPV Cation Channels - agonists | Dopamine - pharmacology | Neural Stem Cells - physiology | Mice, SCID | Arachidonic Acids - pharmacology | TRPV Cation Channels - genetics | Animals | Dopamine - analogs & derivatives | Neoplasm Proteins - agonists | Neural Stem Cells - metabolism | Apoptosis | Care and treatment | Cell death | Brain tumors | Genetic aspects | Diagnosis | Research | Gene expression | Astrocytoma | Pediatrics | Signal transduction | Brain cancer | Neurobiology | Cell and Molecular Biology | Basic Medicine | Medical and Health Sciences | Medicin och hälsovetenskap | Cell- och molekylärbiologi | Medicinska och farmaceutiska grundvetenskaper
Journal Article
Neuropharmacology, ISSN 0028-3908, 06/2013, Volume 69, pp. 115 - 126
Journal Article