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PLoS ONE, ISSN 1932-6203, 01/2014, Volume 9, Issue 1, pp. e86289 - e86289
Infections with helminth parasites prevent/attenuate auto-inflammatory disease. Here we show that molecules secreted by a helminth parasite could prevent Type... 
B-CELLS | ALTERNATIVELY ACTIVATED MACROPHAGES | TGF-BETA | INFLAMMATORY DISEASES | SCHISTOSOMA-MANSONI | IMMUNE-RESPONSES | MULTIDISCIPLINARY SCIENCES | LYMPH-NODES | MICE | INFECTION | TRICHURIS-SUIS THERAPY | T-Lymphocytes, Regulatory - immunology | Helminths - immunology | Autoimmunity - immunology | Female | Diabetes Mellitus, Type 1 - immunology | T-Lymphocytes, Regulatory - parasitology | Transforming Growth Factor beta - immunology | Diabetes Mellitus, Type 1 - parasitology | Lectins - immunology | Macrophages, Peritoneal - immunology | Lymph Nodes - immunology | beta-N-Acetylhexosaminidases - immunology | Pancreas - immunology | B7-H1 Antigen - immunology | Macrophages, Peritoneal - parasitology | Diabetes Mellitus, Experimental - immunology | Diabetes Mellitus, Experimental - parasitology | Cell Differentiation - immunology | Fasciola hepatica - immunology | Autoantibodies - immunology | Animals | Lymph Nodes - parasitology | Interferon-gamma - immunology | Mice, Inbred NOD | Mice | Autoimmunity | Genetic markers | Type 1 diabetes | Environmental law | Immunoglobulin G | B cells | T cells | Health aspects | Insulitis | Disease | Infections | Lymphocytes T | Parasites | Macrophages | Inflammatory diseases | Lymph nodes | Proteins | Prevention | Lymphocytes | Splenocytes | Rodents | Pancreas | Antigens | Autoantibodies | Cytokines | Immunomodulation | Secretion | Diabetes mellitus | Mammals | Gene expression | Insulin | Studies | γ-Interferon | PD-L1 protein | Interferon | Diabetes | Autoimmune diseases | Peritoneum | Index Medicus
Journal Article
Cancer Cell, ISSN 1535-6108, 06/2012, Volume 21, Issue 6, pp. 822 - 835
Cancer-associated inflammation is thought to be a barrier to immune surveillance, particularly in pancreatic ductal adenocarcinoma (PDA). Gr-1 CD11b cells are... 
OVEREXPRESSION | MICROENVIRONMENT | ONCOLOGY | DUCTAL ADENOCARCINOMA | INTERLEUKIN-1-BETA | MICE | SUPPRESSOR-CELLS | INDUCTION | DIFFERENTIATION | MAMMARY CARCINOMAS | MOUSE MODELS | CELL BIOLOGY | Immunohistochemistry | Adenocarcinoma - pathology | CD8-Positive T-Lymphocytes - pathology | Pancreatic Neoplasms - metabolism | Granulocyte-Macrophage Colony-Stimulating Factor - metabolism | Humans | Carcinoma, Pancreatic Ductal - metabolism | Inflammation - metabolism | Adenocarcinoma - metabolism | RNA Interference | T-Lymphocytes - metabolism | Myeloid Cells - immunology | CD8-Positive T-Lymphocytes - metabolism | T-Lymphocytes - pathology | Carcinoma, Pancreatic Ductal - immunology | CD11b Antigen - immunology | Adenocarcinoma - immunology | Pancreatic Neoplasms - pathology | Receptors, Chemokine - metabolism | Mice, Transgenic | Inflammation - immunology | Receptors, Chemokine - immunology | Carcinoma, Pancreatic Ductal - pathology | Granulocyte-Macrophage Colony-Stimulating Factor - genetics | Mice, Knockout | Tumor Microenvironment - immunology | Models, Immunological | Animals | Granulocyte-Macrophage Colony-Stimulating Factor - immunology | Pancreatic Neoplasms - immunology | Cell Line, Tumor | Myeloid Cells - metabolism | T-Lymphocytes - immunology | Mice | CD11b Antigen - metabolism | Myeloid Cells - pathology | CD8-Positive T-Lymphocytes - immunology | Medical colleges | Analysis | Pancreatic cancer | Oncology, Experimental | Genetically modified organisms | Inflammation | Macrophage colony stimulating factor | Research | T cells | Tumors | Cancer | Index Medicus | granulocyte-macrophage colony stimulating factor | myeloid cells | T lymphocyte | carcinoma | pancreas
Journal Article
PLoS ONE, ISSN 1932-6203, 01/2013, Volume 8, Issue 1, pp. e54263 - e54263
Infectious pancreatic necrosis virus (IPNV) is a member of the family Birnaviridae that has been linked to high mortalities in juvenile salmonids and postsmolt... 
CHALLENGE | PROTEIN VP2 | MULTIDISCIPLINARY SCIENCES | BROOK TROUT | VACCINE | AQUATIC BIRNAVIRUSES | MONOCLONAL-ANTIBODIES | VIRULENCE | CARRIER STATE | STRAIN | IPNV | Immunohistochemistry | Threonine - immunology | Amino Acids - immunology | Viral Structural Proteins - immunology | Amino Acids - genetics | Antibodies, Viral - blood | Host-Pathogen Interactions - immunology | Proline - genetics | Salmo salar - virology | Viral Structural Proteins - genetics | Vaccination - methods | Alanine - genetics | Time Factors | Threonine - genetics | Fish Diseases - immunology | Proline - immunology | Pancreas, Exocrine - immunology | Fish Diseases - mortality | Alanine - immunology | Infectious pancreatic necrosis virus - genetics | Survival Rate | Cross Reactions - immunology | Antigens, Viral - immunology | Infectious pancreatic necrosis virus - immunology | Salmo salar - immunology | Vaccines, Attenuated - immunology | Vaccines, Inactivated - immunology | Animals | Fish Diseases - virology | Survival Analysis | Antibodies, Viral - immunology | Infectious pancreatic necrosis virus - physiology | Viral Vaccines - immunology | Pancreas, Exocrine - virology | Medical research | Salmon | Antibodies | Amino acids | Vaccines | Necrosis | Viral antibodies | Fishes | Medicine, Experimental | Cross infection | Virulence (Microbiology) | Nosocomial infections | Sea-water | Enzyme-linked immunosorbent assay | Residues | Immune response | Organs | Viruses | Homology | Infectious pancreatic necrosis | Immune systems | Tat protein | Infectious diseases | Immunogenicity | Salmonids | Genetics | Fish | Pancreas | Strains (organisms) | Neutralization | Seawater | Index Medicus
Journal Article
Immunity, ISSN 1074-7613, 2009, Volume 30, Issue 2, pp. 289 - 299
Journal Article
Journal Article
Immunity, ISSN 1074-7613, 10/2014, Volume 41, Issue 4, pp. 657 - 669
Journal Article
Journal of Immunology, ISSN 0022-1767, 12/2013, Volume 191, Issue 12, pp. 5858 - 5866
Inefficient thymic negative selection of self-specific T cells is associated with several autoimmune diseases, including type 1 diabetes. The factors that... 
GLUTAMIC-ACID DECARBOXYLASE | DENDRITIC CELLS | EPITHELIAL-CELLS | AIRE | NONOBESE DIABETIC MICE | HEMATOPOIETIC STEM-CELLS | BONE-MARROW | NEGATIVE SELECTION | CENTRAL TOLERANCE | IMMUNOLOGY | SELF-TOLERANCE | Salivary Glands - immunology | Salivary Glands - pathology | Clonal Selection, Antigen-Mediated | Transcription Factors - deficiency | Colon - immunology | Adoptive Transfer | Autoimmune Diseases - etiology | T-Lymphocytes, Regulatory - pathology | T-Lymphocytes, Regulatory - immunology | Thymus Gland - transplantation | CD4-Positive T-Lymphocytes - immunology | Aging - immunology | Diabetes Mellitus, Type 1 - etiology | Animals, Suckling | Thymus Gland - pathology | Female | Thymus Gland - growth & development | Diabetes Mellitus, Type 1 - immunology | Colitis - immunology | Animals, Newborn | Transcription Factors - physiology | Specific Pathogen-Free Organisms | Islets of Langerhans - pathology | Colon - pathology | Autoimmune Diseases - immunology | Diabetes Mellitus, Type 1 - pathology | Islets of Langerhans - immunology | Pancreas - pathology | Polyendocrinopathies, Autoimmune - pathology | Mice, Inbred NOD - immunology | Mice, SCID | Organ Specificity | Pancreas - immunology | Mice, Knockout | Polyendocrinopathies, Autoimmune - immunology | Autoimmunity - physiology | Lymphoid Tissue - pathology | Colitis - etiology | Animals | Autoantigens - immunology | Thymus Gland - immunology | Colon - microbiology | Mice | CD8-Positive T-Lymphocytes - immunology | Cytotoxicity, Immunologic | Index Medicus | Abridged Index Medicus
Journal Article
Journal of Immunology, ISSN 0022-1767, 08/2017, Volume 199, Issue 3, pp. 894 - 902
Journal Article
PLoS ONE, ISSN 1932-6203, 05/2014, Volume 9, Issue 5, pp. e96565 - e96565
Objective: The immune response to pancreatic ductal adenocarcinoma (PDA) may play a role in defining its uniquely aggressive biology; therefore, we sought to... 
MULTIDISCIPLINARY SCIENCES | BONE-MARROW | PERIPHERAL-BLOOD | SUPPRESSOR-CELLS | CANCER | CARCINOMA | T-CELLS | TUMOR MICROENVIRONMENT | GEMCITABINE | CLINICAL-SIGNIFICANCE | TH17 CELLS | Adenocarcinoma - pathology | CD8-Positive T-Lymphocytes - pathology | Humans | Middle Aged | Interleukin-17 - immunology | Male | Antineoplastic Agents - therapeutic use | CD4-Positive T-Lymphocytes - pathology | T-Lymphocytes, Regulatory - pathology | T-Lymphocytes, Regulatory - immunology | CD4-Positive T-Lymphocytes - immunology | Aged, 80 and over | Adult | Female | Carcinoma, Pancreatic Ductal - immunology | Tumor Microenvironment - drug effects | Adenocarcinoma - immunology | Pancreas - drug effects | Pancreas - pathology | Pancreas - immunology | Adenocarcinoma - drug therapy | Carcinoma, Pancreatic Ductal - pathology | Carcinoma, Pancreatic Ductal - drug therapy | T-Lymphocytes, Regulatory - drug effects | Granulocyte-Macrophage Colony-Stimulating Factor - immunology | CD8-Positive T-Lymphocytes - drug effects | Interferon-gamma - immunology | Neoadjuvant Therapy - methods | Aged | Programmed Cell Death 1 Receptor - immunology | CD8-Positive T-Lymphocytes - immunology | CD4-Positive T-Lymphocytes - drug effects | Adenocarcinoma | Immunohistochemistry | Interferon | T cells | Comparative analysis | Flow cytometry | Therapy | Animal models | CD8 antigen | Helper cells | Effector cells | Systematic review | Lymphocytes T | Metastasis | Immunity | Cancer therapies | Blood | Metastases | Immunology | Lymphocytes | Surgery | Pancreas | Medical research | Immunological memory | Memory cells | Myeloid cells | Immune response | Cell survival | Immunoregulation | Stroma | Inflammation | Survival | Interleukin 17 | Hemopoiesis | CD4 antigen | Immune systems | Medicine | Studies | Pathology | Cytometry | Immunosuppression | Chemotherapy | Medical prognosis | γ-Interferon | Pancreatic cancer | Infiltration | Evolution & development | Tumors | Apoptosis | Index Medicus
Journal Article