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Genes and Development, ISSN 0890-9369, 08/2011, Volume 25, Issue 16, pp. 1680 - 1685
Journal Article
Diabetes, ISSN 0012-1797, 11/2011, Volume 60, Issue 11, pp. 2872 - 2882
OBJECTIVE-To evaluate whether healthy or diabetic adult mice can tolerate an extreme loss of pancreatic a-cells and how this sudden massive depletion affects... 
INSULIN | HYPERGLUCAGONEMIA | ENDOCRINE PANCREAS | GLUCOSE-HOMEOSTASIS | ENDOCRINOLOGY & METABOLISM | RECEPTOR GENE | SECRETION | DIFFERENTIATION | HYPERPLASIA | ISLET CELLS | EXPRESSION | Insulin-Secreting Cells - secretion | Apoptosis - drug effects | Cell Count | Glucagon - genetics | Male | Diphtheria Toxin - toxicity | Insulin - blood | Glucagon - blood | Diabetes Mellitus, Experimental - blood | Hypoglycemia - prevention & control | Intercellular Signaling Peptides and Proteins - metabolism | Glucagon-Secreting Cells - drug effects | Insulin-Secreting Cells - metabolism | Hyperglycemia - chemically induced | Glucagon-Secreting Cells - metabolism | Diabetes Mellitus, Experimental - chemically induced | Diabetes Mellitus, Experimental - metabolism | Glucagon-Secreting Cells - secretion | Hyperglycemia - prevention & control | Promoter Regions, Genetic | Signal Transduction | Glucagon-Secreting Cells - pathology | Intercellular Signaling Peptides and Proteins - genetics | Pancreas - drug effects | Pancreas - pathology | Receptors, Glucagon - metabolism | Mice, Transgenic | Pancreas - metabolism | Heparin-binding EGF-like Growth Factor | Insulin - metabolism | Animals | Insulin-Secreting Cells - drug effects | Tamoxifen - pharmacology | Diabetes Mellitus, Experimental - pathology | Glucagon - metabolism | Mice | Streptozocin - toxicity | Insulin-Secreting Cells - pathology | Selective Estrogen Receptor Modulators - pharmacology | Index Medicus | Abridged Index Medicus | Islet Studies
Journal Article
Development, ISSN 0950-1991, 01/2010, Volume 137, Issue 2, pp. 203 - 212
The transcription factor neurogenin 3 (Neurog3 or Ngn3) controls islet cell fate specification in multipotent pancreatic progenitor cells in the mouse embryo.... 
Mouse | Rfx | Endocrine | Zebrafish | Cell differentiation | Pancreas | Transcription factor | Neurogenin 3 | PROGENITOR CELLS | NEUROGENIN3 | BETA-CELLS | DEVELOPMENTAL BIOLOGY | HORMONE-EXPRESSING CELLS | PROTEIN ISL-1 | ENDOCRINE PANCREAS | GENE | EMBRYONIC STEM-CELLS | DIFFERENTIATION | Immunohistochemistry | Paired Box Transcription Factors - genetics | Homeodomain Proteins - metabolism | Pancreas - cytology | Winged-Helix Transcription Factors - metabolism | Embryo, Nonmammalian - metabolism | Stem Cells - cytology | Stem Cells - metabolism | Embryo, Mammalian - metabolism | Endocrine Cells - metabolism | In Situ Hybridization | Basic Helix-Loop-Helix Transcription Factors - metabolism | Gene Expression Regulation, Developmental | Islets of Langerhans - metabolism | Islets of Langerhans - cytology | Somatostatin - metabolism | Basic Helix-Loop-Helix Transcription Factors - genetics | Zebrafish Proteins - metabolism | Winged-Helix Transcription Factors - genetics | Cells, Cultured | Pancreas - metabolism | Transcription Factors - genetics | Reverse Transcriptase Polymerase Chain Reaction | Nerve Tissue Proteins - genetics | Pancreas - embryology | Homeodomain Proteins - genetics | Endoderm - metabolism | Ghrelin - metabolism | Nerve Tissue Proteins - metabolism | Transcription Factors - metabolism | Blotting, Northern | Animals | Endocrine Cells - cytology | Glucagon - metabolism | Mice | Zebrafish Proteins - genetics | In Vitro Techniques | Paired Box Transcription Factors - metabolism | Index Medicus | Development and Stem Cells
Journal Article
Cell Metabolism, ISSN 1550-4131, 12/2012, Volume 16, Issue 6, pp. 723 - 737
Journal Article
Nature Communications, ISSN 2041-1723, 12/2018, Volume 9, Issue 1, pp. 546 - 9
Journal Article
Gastroenterology, ISSN 0016-5085, 2014, Volume 146, Issue 7, pp. 1763 - 1774
Background & Aims The NACHT, LRR, and pyrin domain–containing protein 3 (NLRP3) inflammasome induces inflammation in response to organ injury, but little is... 
Gastroenterology and Hepatology | Innate Immune Response | Immune Regulation | Pancreas | Mouse Model | ACTIVATION | NLRP3 INFLAMMASOME | GPR81 | AGONISTS | GENE | TLR9 | MICE | HEPATOTOXICITY | GASTROENTEROLOGY & HEPATOLOGY | EXPRESSION | SEVERITY | Liver - pathology | Inflammasomes - metabolism | Receptors, G-Protein-Coupled - metabolism | NLR Family, Pyrin Domain-Containing 3 Protein | Humans | Male | NF-kappa B - metabolism | Monocytes - immunology | Lipopolysaccharides | Liver - immunology | Liver - drug effects | RNA Interference | Interleukin-1beta - metabolism | Toll-Like Receptors - drug effects | Anti-Inflammatory Agents - administration & dosage | Toll-Like Receptors - metabolism | Cytoprotection | Disease Models, Animal | Galactosamine | Chemical and Drug Induced Liver Injury - prevention & control | Anti-Inflammatory Agents - pharmacology | Down-Regulation | Liver - metabolism | Injections, Intraperitoneal | Pancreas - pathology | Pancreas - metabolism | Pancreas - immunology | Toll-Like Receptor 4 - metabolism | Chemical and Drug Induced Liver Injury - immunology | Monocytes - drug effects | Macrophages - metabolism | Signal Transduction - drug effects | Chemical and Drug Induced Liver Injury - metabolism | Sodium Lactate - pharmacology | beta-Arrestins | Mice | Receptors, G-Protein-Coupled - genetics | RNA, Small Interfering - metabolism | Monocytes - metabolism | Pancreatitis - prevention & control | Arrestins - metabolism | Dose-Response Relationship, Drug | Pancreatitis - genetics | Transfection | Inflammasomes - drug effects | Sodium Lactate - administration & dosage | Pancreatitis - immunology | Chemical and Drug Induced Liver Injury - pathology | Chemical and Drug Induced Liver Injury - etiology | Macrophages - immunology | Cell Line | Immunity, Innate - drug effects | Toll-Like Receptor 4 - drug effects | Mice, Inbred C57BL | Pancreas - drug effects | Chemical and Drug Induced Liver Injury - genetics | Pancreatitis - chemically induced | Animals | Carrier Proteins - metabolism | beta-Arrestin 2 | Inflammasomes - immunology | Macrophages - drug effects | Pancreatitis - pathology | Pancreatitis - metabolism | Ceruletide | Lactates | Gastrointestinal diseases | Inflammation | Index Medicus | Abridged Index Medicus
Journal Article
Gastroenterology, ISSN 0016-5085, 2011, Volume 141, Issue 2, pp. 731 - 741.e4
Background & Aims Animal studies have indicated that pancreatic exocrine acinar cells have phenotypic plasticity. In rodents, acinar cells can differentiate... 
Gastroenterology and Hepatology | Metaplasia | Reprogramming | Exocrine Pancreas | Tissue Engineering | BETA-CELLS | INTRAEPITHELIAL NEOPLASIA | HUMAN EXOCRINE PANCREAS | ADULT HUMAN PANCREAS | IN-VITRO | NOTCH SIGNALING PATHWAY | GENERATION | MICE | GROWTH-FACTOR | DIFFERENTIATION | GASTROENTEROLOGY & HEPATOLOGY | Cell Proliferation | Chymotrypsin - metabolism | Humans | Glycoproteins - metabolism | Carbonic Anhydrase II - metabolism | Ki-67 Antigen - metabolism | Cell Transdifferentiation - genetics | RNA, Messenger - metabolism | Pancreatic Ducts - metabolism | Antigens, CD - metabolism | Cell Transdifferentiation - physiology | Peptides - metabolism | Pancreas, Exocrine - cytology | Cell Lineage - genetics | Genes, Reporter | Hepatocyte Nuclear Factor 1-beta - metabolism | Plant Lectins - pharmacokinetics | Biomarkers - metabolism | SOX9 Transcription Factor - metabolism | Green Fluorescent Proteins - metabolism | Promoter Regions, Genetic | Pancreatic Ducts - cytology | Transduction, Genetic | Cell Survival | Cells, Cultured | Cystic Fibrosis Transmembrane Conductance Regulator - metabolism | Signal Transduction - genetics | AC133 Antigen | Cell Lineage - physiology | Phenotype | Signal Transduction - physiology | Pancreas, Exocrine - metabolism | Keratin-19 - metabolism | Mitogen-Activated Protein Kinases - metabolism | Keratin | Epidermal growth factor | Analysis | Fluorescein | Fluorescence | Cystic fibrosis | Diabetes | Universities and colleges | Research | Protein kinases | Index Medicus | Abridged Index Medicus
Journal Article
Genome Research, ISSN 1088-9051, 01/2011, Volume 21, Issue 1, pp. 95 - 105
Journal Article
Journal of Experimental Medicine, ISSN 0022-1007, 06/2013, Volume 210, Issue 6, pp. 1137 - 1151
Journal Article
Histochemistry and Cell Biology, ISSN 0948-6143, 11/2011, Volume 136, Issue 5, pp. 595 - 607
Journal Article
Obesity, ISSN 1930-7381, 03/2008, Volume 16, Issue 3, pp. 553 - 565
Journal Article