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Journal of radiation research, ISSN 0449-3060, 09/2018, Volume 59, Issue 5, pp. 529 - 540
Journal Article
Molecular Cancer, ISSN 1476-4598, 07/2013, Volume 12, Issue 1, pp. 81 - 81
Background: Radiation exerts direct antitumor effects and is widely used in clinics, but the efficacy is severely compromised by tumor resistance. Therefore... 
mTOR | Radiation resistance | AZD8055 | Pancreatic cancer | MAMMALIAN TARGET | RAPAMYCIN | ACTIVATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | KINASE | DOWN-REGULATION | DRUG-RESISTANCE | CELL-LINES | RADIATION | INHIBITION | ONCOLOGY | EXPRESSION | Cell Cycle - genetics | TOR Serine-Threonine Kinases - metabolism | Apoptosis - drug effects | Apoptosis - radiation effects | Humans | Up-Regulation - radiation effects | Apoptosis - genetics | MicroRNAs - metabolism | Down-Regulation - radiation effects | Pancreatic Neoplasms - drug therapy | Radiation Tolerance - radiation effects | TOR Serine-Threonine Kinases - genetics | Female | Gene Expression Regulation, Neoplastic - drug effects | Morpholines - therapeutic use | Radiation, Ionizing | Cell Cycle - radiation effects | Pancreatic Neoplasms - pathology | Morpholines - pharmacology | Pancreatic Neoplasms - radiotherapy | Radiation Tolerance - genetics | Pancreatic Neoplasms - genetics | Treatment Outcome | Up-Regulation - genetics | Down-Regulation - drug effects | Down-Regulation - genetics | Radiation Tolerance - drug effects | Up-Regulation - drug effects | Xenograft Model Antitumor Assays | Phosphorylation - radiation effects | Animals | Mice, Nude | Cell Line, Tumor | Gene Expression Regulation, Neoplastic - radiation effects | MicroRNAs - genetics | Cell Cycle - drug effects | Ionizing radiation | MicroRNA | Drug resistance | Genetic regulation | Radiation therapy | Pancreas | Kinases | Rodents | Tumors | Index Medicus
Journal Article
International Journal of Radiation Oncology, Biology, Physics, ISSN 0360-3016, 2012, Volume 84, Issue 5, pp. 1166 - 1171
Purpose Local failure in unresectable pancreatic cancer may contribute to death. We hypothesized that intensification of local therapy would improve local... 
Radiology | Hematology, Oncology and Palliative Medicine | RATE INFUSION | THERAPY | RADIOSENSITIZATION | ONCOLOGY | ADENOCARCINOMA | I TRIAL | MAINTENANCE GEMCITABINE | RADIOTHERAPY | CARCINOMA | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | Organs at Risk - radiation effects | Adenocarcinoma - pathology | Humans | Middle Aged | Gastrointestinal Tract - radiation effects | Male | Cause of Death | Radiotherapy, Intensity-Modulated - adverse effects | Neutropenia - etiology | Radiation-Sensitizing Agents - administration & dosage | Time Factors | Aged, 80 and over | Deoxycytidine - adverse effects | Dose Fractionation | Female | Pancreatic Neoplasms - mortality | Adenocarcinoma - radiotherapy | Deoxycytidine - administration & dosage | Pancreatic Neoplasms - pathology | Radiotherapy, Intensity-Modulated - methods | Pancreatic Neoplasms - radiotherapy | Thrombocytopenia - chemically induced | Radiation-Sensitizing Agents - adverse effects | Disease Progression | Maximum Tolerated Dose | Aged | Deoxycytidine - analogs & derivatives | Adenocarcinoma - mortality | Cancer patients | Care and treatment | Gemcitabine | Nuclear radiation | Pancreatic cancer | Clinical trials | Product development | Cancer | Index Medicus | Adenocarcinoma | PATIENTS | VOMITING | FAILURES | PERFORMANCE | PANCREAS | NEUTROPHILS | DEATH | RADIATION DOSES | TOXICITY | BILIRUBIN | ALANINES | DEHYDRATION | CARCINOMAS | CREATININE | NAUSEA | RADIOLOGY AND NUCLEAR MEDICINE | DOSE RATES | ANOREXIA | FEVER | PERFORATION | chemoradiotherapy | pancreatic cancer | gemcitabine | IMRT | local control
Journal Article
Journal Article
Medical Physics, ISSN 0094-2405, 08/2014, Volume 41, Issue 8, pp. 154 - n/a
Purpose: Uncontrolled local growth is the cause of death in ∼30% of patients with unresectable pancreatic cancers. The addition of standard-dose radiotherapy... 
toxicology | PBS | Kidneys | dosimetry | IMRT | Therapeutic applications | liver | Medical treatment planning | Photons | Scintigraphy | Proton therapy | Dose‐volume analysis | unresectable | kidney | Intensity modulated radiation therapy | Conformal radiation therapy | pancreas | radiation therapy | protons | Therapeutic applications, including brachytherapy | statistical testing | Cancer | Dosimetry/exposure assessment | FEASIBILITY | MODULATED RADIOTHERAPY IMRT | GEMCITABINE | CAPECITABINE | DOSE-ESCALATION | REDUCTION | ACUTE GASTROINTESTINAL TOXICITY | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | Radiotherapy Dosage | Humans | Middle Aged | Pancreatic Neoplasms - pathology | Pancreas - pathology | Pancreatic Neoplasms - radiotherapy | Protons - therapeutic use | Spinal Cord - radiation effects | Liver - radiation effects | Male | Tumor Burden | Photons - therapeutic use | Kidney - radiation effects | Proton Therapy | Duodenum - radiation effects | Female | Intestine, Small - radiation effects | Aged | Stomach - radiation effects | Pancreas - radiation effects | Radiotherapy Planning, Computer-Assisted | Radiotherapy, Intensity-Modulated | Index Medicus | SMALL INTESTINE | CRITICAL ORGANS | PATIENTS | NEOPLASMS | PANCREAS | RADIATION DOSES | TOXICITY | THREE-DIMENSIONAL CALCULATIONS | 60 APPLIED LIFE SCIENCES | PLANNING | KIDNEYS | LIVER | RADIOTHERAPY | SCATTERING | STOMACH
Journal Article
International Journal of Radiation Oncology, Biology, Physics, ISSN 0360-3016, 2011, Volume 81, Issue 1, pp. 181 - 188
Purpose This Phase II trial evaluated the toxicity, local control, and overall survival in patients treated with sequential gemcitabine and linear... 
Radiology | Hematology, Oncology and Palliative Medicine | Stereotactic body radiotherapy | Image-guided radiotherapy | Gemcitabine | Pancreatic cancer | CHEMORADIOTHERAPY | RADIOSURGERY | CHEMOTHERAPY | TRIAL | 5-FLUOROURACIL | ONCOLOGY | RANDOMIZED PHASE-III | FULL-DOSE GEMCITABINE | RADIOTHERAPY | UNRESECTABLE ADENOCARCINOMA | CARCINOMA | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | Radiotherapy Dosage | Adenocarcinoma - pathology | Prospective Studies | Drug Administration Schedule | Deoxycytidine - administration & dosage | Humans | Middle Aged | Pancreatic Neoplasms - pathology | Pancreatic Neoplasms - surgery | Male | Combined Modality Therapy - mortality | Adenocarcinoma - drug therapy | Feasibility Studies | Pancreatic Neoplasms - drug therapy | Aged, 80 and over | Deoxycytidine - adverse effects | Female | Aged | Combined Modality Therapy - methods | Pancreatic Neoplasms - mortality | Radiosurgery - methods | Deoxycytidine - analogs & derivatives | Adenocarcinoma - mortality | Adenocarcinoma - surgery | Care and treatment | Radiotherapy | Radiation | Cancer | Index Medicus | TOMOGRAPHY | GASTROINTESTINAL TRACT | DIGESTIVE SYSTEM | RADIATION EFFECTS | PANCREAS | MEDICINE | THERAPY | GLANDS | BIOLOGICAL EFFECTS | ENDOCRINE GLANDS | RADIOLOGY AND NUCLEAR MEDICINE | BIOLOGICAL RADIATION EFFECTS | RADIOLOGY | SMALL INTESTINE | ULCERS | DIAGNOSTIC TECHNIQUES | INJURIES | NEOPLASMS | TOXICITY | INTESTINES | COMPUTERIZED TOMOGRAPHY | RADIATION INJURIES | NUCLEAR MEDICINE | ORGANS | DISEASES | CARCINOMAS | BODY | PATHOLOGICAL CHANGES | PERFORATION
Journal Article
International Journal of Radiation Oncology, Biology, Physics, ISSN 0360-3016, 2016, Volume 97, Issue 2, pp. 323 - 332
Journal Article
PLoS ONE, ISSN 1932-6203, 11/2017, Volume 12, Issue 11, pp. e0186340 - e0186340
The aim of this study is to assess the radiation absorbed dose of F-18-Fluoro-L-DOPA derived from the Positron Emission Tomography (PET) images of infants age... 
AMINO-ACID DECARBOXYLASE | INSULIN | F-18-FDOPA PET/CT | COMPUTED TOMOGRAPHY | POSITRON-EMISSION-TOMOGRAPHY | FOCAL FORM | F-18-DOPA PET | MULTIDISCIPLINARY SCIENCES | L-DOPA | PARKINSONS-DISEASE | BRAIN-TUMORS | Muscles - radiation effects | Humans | Infant | Liver - radiation effects | Male | Positron-Emission Tomography | Radiation Dosage | Tissue Distribution - radiation effects | Congenital Hyperinsulinism - metabolism | Kidney - radiation effects | Congenital Hyperinsulinism - pathology | Image Processing, Computer-Assisted | Levodopa - administration & dosage | Female | Lung - radiation effects | Radiometry - methods | Pancreas - radiation effects | Congenital Hyperinsulinism - diagnostic imaging | Infant, Newborn | Phenols | CT imaging | Infants | Genetic disorders | PET imaging | Radiation | Neonates | Dosimeters | Biomedical research | Liver | Emission analysis | Bladder | Amino acids | Image reconstruction | Computed tomography | Urinary bladder | Mathematical analysis | Tomography | Levodopa | Dosimetry | Pancreas | Radioactivity | Dihydroxyphenylalanine | Excretion | Kidneys | Dopamine | Congenital diseases | Medical imaging | Organs | Positron emission | Muscles | Radiation dosimetry | Metabolism | Insulin | Radiation dosage | Studies | Babies | Lungs | Adults | Dopa | Positron emission tomography | Kidney transplantation | Index Medicus
Journal Article
International Journal of Radiation Oncology, Biology, Physics, ISSN 0360-3016, 2012, Volume 83, Issue 5, pp. 1355 - 1364
Summary Pancreatic carcinoma is a leading cause of cancer-related mortality. Approximately 30% of pancreatic cancer patients present with locally advanced,... 
Radiology | Hematology, Oncology and Palliative Medicine | Pancreatic adenocarcinoma | Intensity-modulated radiation therapy | Quality assurance | Chemoradiotherapy | Locally advanced | CONSOLIDATIVE CHEMORADIATION | INTENSITY-MODULATED RADIOTHERAPY | RADIATION-THERAPY | DOSE-ESCALATION | STEREOTACTIC RADIOSURGERY | ONCOLOGY | PHASE-I TRIAL | MAINTENANCE GEMCITABINE | TUMOR MOTION | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | COOPERATIVE-ONCOLOGY-GROUP | CONCURRENT CAPECITABINE | Chemoradiotherapy - standards | Organs at Risk - radiation effects | Radiotherapy Planning, Computer-Assisted - methods | United States | Humans | Spinal Cord - radiation effects | Liver - radiation effects | Pancreatic Neoplasms - drug therapy | Clinical Trials, Phase III as Topic | Kidney - diagnostic imaging | Liver - diagnostic imaging | Intestine, Small - radiation effects | Stomach - radiation effects | France | Stomach - diagnostic imaging | Radiotherapy Dosage | Chemoradiotherapy - methods | Pancreatic Neoplasms - pathology | Radiotherapy, Intensity-Modulated - methods | Spinal Cord - diagnostic imaging | Pancreatic Neoplasms - radiotherapy | Tumor Burden | Quality Assurance, Health Care | Randomized Controlled Trials as Topic | Radiography | Kidney - radiation effects | Organs at Risk - diagnostic imaging | Intestine, Small - diagnostic imaging | Clinical Trials, Phase II as Topic | Radiotherapy, Conformal - methods | Online health care information services | Chemotherapy | Analysis | Oncology, Experimental | Pancreatic cancer | Radiation | Universities and colleges | Research | Radiotherapy | Cancer | Index Medicus | MORTALITY | PATIENTS | QUALITY ASSURANCE | CLINICAL TRIALS | PANCREAS | RADIATION DOSES | CHEMOTHERAPY | PLANNING | KIDNEYS | IRRADIATION | SPINAL CORD | HEALTH HAZARDS | RECOMMENDATIONS | LIVER | CARCINOMAS | RADIOLOGY AND NUCLEAR MEDICINE | RADIOTHERAPY | COMBINED THERAPY | STOMACH
Journal Article
International Journal of Radiation Oncology, Biology, Physics, ISSN 0360-3016, 2016, Volume 94, Issue 4, pp. 755 - 765
Journal Article