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Gastroenterology, ISSN 0016-5085, 2008, Volume 135, Issue 2, pp. 621 - 631.e8
Although both endocrine and the exocrine pancreas display a significant capacity for tissue regeneration and renewal, the existence of progenitor cells in the... 
Gastroenterology and Hepatology | ACINAR-CELL | AXOLOTL TAIL REGENERATION | GROWTH-FACTOR-ALPHA | MOUSE | STEM-CELL | BETA-CELL | PROLIFERATION | DIFFERENTIATION | GASTROENTEROLOGY & HEPATOLOGY | CANCER | TRANSDIFFERENTIATION | Nestin | Cell Proliferation | Epithelial Cells - metabolism | Receptors, G-Protein-Coupled - metabolism | Epithelial Cells - drug effects | Pancreatic Ducts - drug effects | Pancreas, Exocrine - pathology | Hedgehog Proteins - metabolism | Pancreatic Ducts - pathology | Pancreas, Exocrine - drug effects | Stem Cells - metabolism | Pancreatic Ducts - metabolism | Time Factors | Smoothened Receptor | Veratrum Alkaloids - pharmacology | Cell Differentiation | Genes, Reporter | Disease Models, Animal | Mice, Inbred C57BL | Epithelial Cells - pathology | Mice, Transgenic | Pancreatic Elastase - metabolism | Pancreatitis - chemically induced | Cell Transformation, Neoplastic - metabolism | Nerve Tissue Proteins - metabolism | Metaplasia | Regeneration - drug effects | Animals | Signal Transduction - drug effects | Stem Cells - drug effects | Stem Cells - pathology | Pancreatitis - pathology | Mice | Pancreas, Exocrine - metabolism | Receptors, G-Protein-Coupled - genetics | Pancreatitis - metabolism | Ceruletide | Intermediate Filament Proteins - metabolism | Research | Pancreatic cancer | Analysis | Oncology, Experimental | Cancer | Index Medicus | Abridged Index Medicus
Journal Article
Diabetes, ISSN 0012-1797, 12/2015, Volume 64, Issue 12, pp. 4123 - 4134
The exocrine pancreas can give rise to endocrine insulin-producing cells upon ectopic expression of key transcription factors. However, the need for genetic... 
PROGENITOR CELLS | INSULIN | IN-VITRO | EMBRYONIC STEM-CELLS | MOUSE | ENDOCRINOLOGY & METABOLISM | OSTEOGENIC PROTEIN-1 | MESENCHYMAL TRANSITION | IDENTIFICATION | BETA-LIKE CELLS | EXPRESSION | C-Peptide - blood | Bone Morphogenetic Protein 7 - genetics | Homeodomain Proteins - metabolism | Humans | Pancreas, Exocrine - pathology | Male | Transplantation, Heterologous | Pancreas, Exocrine - drug effects | Diabetes Mellitus, Experimental - therapy | Kidney | Diabetes Mellitus, Experimental - blood | Insulin-Secreting Cells - metabolism | Cell Transdifferentiation - drug effects | Diabetes Mellitus, Experimental - metabolism | C-Peptide - metabolism | Insulin Secretion | Biomarkers - metabolism | Recombinant Proteins - metabolism | Cells, Cultured | Transplantation, Heterotopic | Recombinant Proteins - pharmacology | Cell Lineage | Insulin - metabolism | Animals | Insulin-Secreting Cells - drug effects | Mice, Nude | Bone Morphogenetic Protein 7 - metabolism | Fluorescent Antibody Technique | Diabetes Mellitus, Experimental - pathology | Trans-Activators - metabolism | Pancreas, Exocrine - metabolism | Insulin-Secreting Cells - pathology | Bone Morphogenetic Protein 7 - pharmacology | Insulin-Secreting Cells - transplantation | Care and treatment | Analysis | Aging | Insulin resistance | Cystic fibrosis | Influence | Diabetes | Research | Islet Studies
Journal Article
Diabetic Medicine, ISSN 0742-3071, 08/2013, Volume 30, Issue 8, pp. 946 - 955
Journal Article
Journal Article
American Journal of Pathology, The, ISSN 0002-9440, 2016, Volume 186, Issue 11, pp. 2934 - 2944
Journal Article
PLoS Genetics, ISSN 1553-7390, 04/2017, Volume 13, Issue 4, p. e1006740
Arf4 is proposed to be a critical regulator of membrane protein trafficking in early secretory pathway. More recently, Arf4 was also implicated in regulating... 
ADP-RIBOSYLATION FACTOR | ROD PHOTORECEPTORS | C-TERMINUS | TRANSGENIC MOUSE | GENETICS & HEREDITY | MITOTIC SPINDLE | TRAFFICKING | OUTER SEGMENT | INTRAFLAGELLAR TRANSPORT PROTEIN | DOMINANT RETINITIS-PIGMENTOSA | PRIMARY CILIA | Sequence Deletion | Cilia - pathology | Kidney - pathology | Nucleotide Motifs - genetics | Retinal Degeneration - genetics | Humans | Pancreas, Exocrine - pathology | Cilia - genetics | Kidney Diseases, Cystic - pathology | Mice, Knockout | Kidney - metabolism | Animals | Pancreas, Exocrine - growth & development | Photoreceptor Cells - metabolism | Kidney Diseases, Cystic - genetics | Mice | Photoreceptor Cells - pathology | Retinal Degeneration - pathology | ADP-Ribosylation Factors - genetics | Disease Models, Animal | Gene mutations | Retinal degeneration | Physiological aspects | Genetic aspects | Research | Risk factors | Membrane proteins | Funding | Colleges & universities | Retina | Biochemistry | Lethality | Assaying | Dehydrogenase | Proteins | Assembly | Obesity | Data acquisition | Abnormalities | Amino acid sequence | Electron microscopy | Organelles | Stem cells | Cytoskeleton | Mutation | Collecting duct | Kidney transplantation | Anomalies | Residues | Membranes | Retinitis pigmentosa | Amino acids | Cases (containers) | Rod outer segment membranes | Medical schools | Defects | Visual perception | Malfunctions | Specialization | Clonal deletion | Rodents | Degeneration | Pancreas | Cilia | Data processing | C-Terminus | Medicine | Vertebrates | Cell death | Hedgehog protein | Coiling | Blindness | Photoreceptors | Kidney diseases | Position (location) | Collapsin response mediator protein 2
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 12/2008, Volume 105, Issue 48, pp. 18913 - 18918
Journal Article
Gastroenterology, ISSN 0016-5085, 2008, Volume 134, Issue 7, pp. 2080 - 2090
Background & Aims: Although the cell of origin for pancreatic cancer remains unknown, prior studies have suggested that pancreatic neoplasia may be initiated... 
Gastroenterology and Hepatology | COOPERATE | TRANSGENIC ZEBRAFISH | DUCTAL ADENOCARCINOMA | ACUTE LYMPHOBLASTIC-LEUKEMIA | MOUSE | DIFFERENTIATION | GASTROENTEROLOGY & HEPATOLOGY | CANCER | HEDGEHOG | PROGRESSION | REQUIREMENT | ras Proteins - genetics | Proto-Oncogene Proteins p21(ras) | Cell Proliferation | Pancreatic Neoplasms - metabolism | Humans | Gene Expression Regulation, Neoplastic | Pancreas, Exocrine - pathology | Hedgehog Proteins - metabolism | ras Proteins - metabolism | Recombinant Fusion Proteins - metabolism | Neoplasms, Experimental - pathology | Neoplastic Stem Cells - metabolism | Time Factors | Cell Transformation, Neoplastic - genetics | Chromosomes, Artificial, Bacterial | Neoplasms, Experimental - genetics | Neoplastic Stem Cells - pathology | Cell Differentiation | Proto-Oncogene Proteins - metabolism | Green Fluorescent Proteins - metabolism | Signal Transduction | Animals, Genetically Modified | Neoplasm Invasiveness | Pancreatic Neoplasms - pathology | Pancreatic Neoplasms - enzymology | Genotype | Pancreatic Neoplasms - genetics | Proto-Oncogene Proteins - genetics | Transcription Factors - genetics | Cell Transformation, Neoplastic - metabolism | Zebrafish - genetics | Phenotype | Animals | Zebrafish - metabolism | Pancreas, Exocrine - metabolism | Neoplasms, Experimental - metabolism | Cell Transformation, Neoplastic - pathology | Microscopy, Fluorescence | Cell Movement | Research | Pancreatic cancer | Oncology, Experimental | Cancer
Journal Article