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PloS one, ISSN 1932-6203, 02/2016, Volume 11, Issue 2, pp. e0148252 - e0148252
Fibroblast growth factor 21 (FGF21) is an important endocrine metabolic regulator expressed in multiple tissues including liver and adipose tissue. Although... 
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Tumor Necrosis Factor-alpha - metabolism | Pancreatitis - etiology | Tumor Necrosis Factor-alpha - genetics | Fibroblast Growth Factors - genetics | Male | Interferon-gamma - metabolism | Obesity - genetics | Fibroblast Growth Factors - metabolism | Pancreatitis - genetics | Hyperplasia - genetics | Forkhead Transcription Factors - metabolism | Islets of Langerhans - metabolism | Diet, High-Fat | Mitogen-Activated Protein Kinase 1 - genetics | Thy-1 Antigens - genetics | Obesity - etiology | Interferon-gamma - genetics | Hyperplasia - metabolism | Acinar Cells - metabolism | Dietary Fats - adverse effects | Fasting | Islets of Langerhans - pathology | Mitogen-Activated Protein Kinase 3 - genetics | Signal Transduction | Mice, Inbred C57BL | Gene Expression Regulation | Inflammation | Forkhead Transcription Factors - genetics | Organ Specificity | Receptors, Antigen, T-Cell, alpha-beta - genetics | Hyperplasia - etiology | Obesity - metabolism | Obesity - pathology | Hyperplasia - pathology | Thy-1 Antigens - metabolism | Acinar Cells - pathology | Animals | Mitogen-Activated Protein Kinase 3 - metabolism | Pancreatitis - pathology | Mice | Pancreatitis - metabolism | Receptors, Antigen, T-Cell, alpha-beta - metabolism | Mitogen-Activated Protein Kinase 1 - metabolism | Fibroblast growth factor | Phosphorylation | Adipose tissue | Laboratories | Liver | Hyperplasia | Lymphocytes T | Biology | Tissues | High fat diet | Infusion | Cell growth | Lymphocytes | Rodents | Interleukin 1 | Fibroblasts | Foxp3 protein | Physiology | Pancreas | Growth factors | Acinar cells | Cytokines | Immunoregulation | Extracellular signal-regulated kinase | Tumor necrosis factor-α | Metabolism | Fatty acids | Studies | Diet | γ-Interferon | Islet cells | Insulin resistance | Islets of Langerhans | Diabetes | Endocrinology | Index Medicus
Journal Article
Gastroenterology (New York, N.Y. 1943), ISSN 0016-5085, 2009, Volume 137, Issue 1, pp. 350 - 360.e5
Journal Article
Oncogene, ISSN 1476-5594, 08/2016, Volume 36, Issue 9, pp. 1232 - 1244
Pancreatic ductal adenocarcinoma (PDAC) is characterized by a high degree of inflammation and profound immune suppression. Here we identify Yes-associated... 
Biochemistry & Molecular Biology | Oncology | Genetics & Heredity | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Inflammation - pathology | Adenocarcinoma - pathology | Cell Proliferation | Pancreatic Neoplasms - metabolism | Prognosis | Proto-Oncogene Proteins p21(ras) - genetics | Humans | Carcinoma, Pancreatic Ductal - metabolism | Phosphoproteins - metabolism | Inflammation - metabolism | Adenocarcinoma - metabolism | T-Lymphocytes - metabolism | Biomarkers, Tumor - metabolism | Pancreatitis - immunology | Cell Differentiation | Phosphoproteins - physiology | T-Lymphocytes - pathology | Tumor Cells, Cultured | Carcinoma, Pancreatic Ductal - immunology | Macrophages - immunology | Myeloid-Derived Suppressor Cells - metabolism | Myeloid-Derived Suppressor Cells - pathology | Acute Disease | Myeloid-Derived Suppressor Cells - immunology | Cytokines - metabolism | Macrophages - pathology | Adenocarcinoma - immunology | Pancreatic Neoplasms - pathology | Survival Rate | Inflammation - immunology | Phosphoproteins - genetics | Mutation - genetics | Carcinoma, Pancreatic Ductal - pathology | Xenograft Model Antitumor Assays | Adaptor Proteins, Signal Transducing - physiology | Macrophages - metabolism | Animals | Pancreatic Neoplasms - immunology | Adaptor Proteins, Signal Transducing - genetics | Pancreatitis - pathology | T-Lymphocytes - immunology | Mice | Pancreatitis - metabolism | Adaptor Proteins, Signal Transducing - metabolism | Neoplasm Staging | Apoptosis | Proteins | Inflammation | Cytokines | Pancreatic cancer | Index Medicus | PDAC | MDSC | inflammation | acute pancreatitis | YAP | T cells | Macrophages
Journal Article
Gut, ISSN 0017-5749, 06/2014, Volume 63, Issue 6, pp. 903 - 910
Objective Although polymorphisms of the NOD2 gene predispose to the development of ileal Crohn's disease, the precise mechanisms of this increased... 
Gastroenterology & Hepatology | Life Sciences & Biomedicine | Science & Technology | Defensins - metabolism | Defensins - genetics | Escherichia coli - drug effects | Peptides - genetics | Ileum - metabolism | Nod2 Signaling Adaptor Protein - genetics | RNA, Messenger - metabolism | alpha-Defensins - genetics | Microbial Sensitivity Tests | Salmonella enterica - drug effects | Feces - microbiology | Lectins, C-Type - metabolism | Peptides - metabolism | Antigens, Neoplasm - metabolism | Biomarkers, Tumor - metabolism | Transcription, Genetic | alpha-Defensins - metabolism | Ileum - cytology | Paneth Cells - metabolism | Protein Precursors - genetics | Mice, Inbred C57BL | Paneth Cells - cytology | Ribonuclease, Pancreatic - genetics | Muramidase - metabolism | Pancreatitis-Associated Proteins | Mice, Knockout | Protein Precursors - metabolism | alpha-Defensins - pharmacology | Animals | Nod2 Signaling Adaptor Protein - metabolism | Ribonuclease, Pancreatic - metabolism | Analysis | Antimicrobial peptides | Crohn's disease | Genetic aspects | Research | Gene expression | Risk factors | Genetic polymorphisms | Studies | Pathogenesis | Rodents | Antimicrobial agents | Inflammation | Clinical medicine | Laboratory animals | Crohns disease | Index Medicus | Abridged Index Medicus | IBD - GENETICS | INTESTINAL EPITHELIUM | BACTERIAL INTERACTIONS | CROHN'S DISEASE | Inflammatory Bowel Disease | 1506
Journal Article
Endocrinology, ISSN 0013-7227, 11/2015, Volume 156, Issue 11, pp. 3937 - 3949
Journal Article
BMC gastroenterology, ISSN 1471-230X, 11/2014, Volume 14, Issue 1, pp. 189 - 189
Data are accumulating that emphasize the important role of the intestinal barrier and intestinal permeability for health and disease. However, these terms are... 
Intestinal barrier | Obesity | CLOSTRIDIUM-DIFFICILE INFECTION | Tight junctions | HIGH-FAT DIET | Intestinal permeability | Prebiotics | Inflammatory bowel disease | Probiotics | Microbiota | APICAL-JUNCTIONAL COMPLEX | ENTEROPATHOGENIC ESCHERICHIA-COLI | Irritable bowel syndrome | EPITHELIAL BARRIER FUNCTION | HELICOBACTER-PYLORI CAGA | PLACEBO-CONTROLLED TRIAL | SEROTONIN REUPTAKE TRANSPORTER | IRRITABLE-BOWEL-SYNDROME | Gut health | SEVERE ACUTE-PANCREATITIS | Gastroenterology & Hepatology | Life Sciences & Biomedicine | Science & Technology | Biomarkers - metabolism | Probiotics - administration & dosage | Intestinal Mucosa - metabolism | Fatty Liver - metabolism | Humans | Critical Illness | Intestines - metabolism | Permeability | Inflammatory Bowel Diseases - metabolism | Intestines - immunology | Obesity - metabolism | Histamine - metabolism | Receptor, Cannabinoid, CB1 - metabolism | Animals | Intestines - microbiology | Diet | Intestinal Mucosa - immunology | Serotonin - metabolism | Ion Transport | Peptide Hydrolases - metabolism | Disease prevention | Medical research | Nutrition research | Immunology | Biomedical research | Research parks | Colleges & universities | Small intestine | Index Medicus | serotonin reuptake transporter | severe acute-pancreatitis | helicobacter-pylori caga | placebo-controlled trial | apical | high-fat diet | enteropathogenic escherichia-coli | irritable-bowel-syndrome | clostridium-difficile infection | epithelial barrier function
Journal Article