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Arteriosclerosis, Thrombosis, and Vascular Biology, ISSN 1079-5642, 09/2008, Volume 28, Issue 9, pp. 1654 - 1659
Journal Article
Archives of Pathology and Laboratory Medicine, ISSN 0003-9985, 10/2014, Volume 138, Issue 10, pp. 1337 - 1343
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 9/2016, Volume 113, Issue 36, pp. 10127 - 10132
Systemic autoinflammatory diseases are caused by mutations in genes that function in innate immunity. Here, we report an autoinflammatory disease caused by... 
Autoinflammatory disease | Cytokines | Nf-κb pathway | Linear deubiquitinase | OTULIN | ACTIVATION | AMYLOPECTINOSIS | NF-kappa B pathway | UBIQUITIN | MULTIDISCIPLINARY SCIENCES | linear deubiquitinase | ASSEMBLY COMPLEX | CELL-DEATH | HOIP | SHARPIN | autoinflammatory disease | INFLAMMATION | LUBAC DEFICIENCY | cytokines | IMMUNODEFICIENCY | Fibroblasts - enzymology | Humans | NF-kappa B - immunology | Child, Preschool | Male | Fever - physiopathology | Leukocytes, Mononuclear - immunology | HEK293 Cells | Female | Child | Cytokines - genetics | Failure to Thrive - physiopathology | Hereditary Autoinflammatory Diseases - pathology | Cytokines - immunology | Dermatitis - physiopathology | Signal Transduction | Hereditary Autoinflammatory Diseases - enzymology | Gene Expression Regulation | Ubiquitin - genetics | Endopeptidases - deficiency | Hereditary Autoinflammatory Diseases - diagnosis | Fibroblasts - pathology | Endopeptidases - immunology | Leukocytes, Mononuclear - pathology | Endopeptidases - genetics | NF-kappa B - genetics | Pedigree | Age of Onset | Alleles | Fibroblasts - immunology | Leukocytes, Mononuclear - enzymology | Panniculitis - physiopathology | Consanguinity | Mutation | Ubiquitin - immunology | Hereditary Autoinflammatory Diseases - genetics | Allelomorphism | Genetic aspects | Gene mutations | Autoimmune diseases | Health aspects | Biological Sciences | NF-κB pathway
Journal Article
Arteriosclerosis, Thrombosis, and Vascular Biology, ISSN 1079-5642, 07/2008, Volume 28, Issue 7, pp. 1304 - 1310
Journal Article
Diabetes/Metabolism Research and Reviews, ISSN 1520-7552, 09/2015, Volume 31, Issue 6, pp. 545 - 561
Summary Obesity is associated with a systemic chronic low‐grade inflammation that contributes to the development of metabolic disorders such as cardiovascular... 
microbiota | intestinal epithelial cells | type 2 diabetes | inflammation | muscular cells | adipose cells | high‐fat diet | cytokines | TLR | gut peptides | obesity | Type 2 diabetes | Obesity | Microbiota | Cytokines | Adipose cells | High-fat diet | Gut peptides | Intestinal epithelial cells | Inflammation | Muscular cells | OXIDATIVE STRESS | NECROSIS-FACTOR-ALPHA | METABOLICALLY HEALTHY | GUT MICROBIOTA | INDUCED INSULIN-RESISTANCE | TOLL-LIKE RECEPTOR-4 | SIGNALING PATHWAY | high-fat diet | ENDOCRINOLOGY & METABOLISM | REGULATORY T-CELLS | ENDOPLASMIC-RETICULUM | Intestinal Mucosa - metabolism | Adipose Tissue, White - immunology | Diabetes Mellitus, Type 2 - microbiology | Myositis - etiology | Obesity - immunology | Humans | Immunity, Mucosal | Intestinal Mucosa - secretion | Adipose Tissue, White - metabolism | Diet, High-Fat - adverse effects | Muscle, Skeletal - metabolism | Gastrointestinal Hormones - secretion | Diabetes Mellitus, Type 2 - metabolism | Obesity - microbiology | Myositis - immunology | Muscle, Skeletal - immunology | Systemic Vasculitis - microbiology | Intestinal Mucosa - immunology | Diabetes Mellitus, Type 2 - immunology | Panniculitis - microbiology | Gastrointestinal Hormones - metabolism | Systemic Vasculitis - etiology | Diabetes Mellitus, Type 2 - etiology | Obesity - etiology | Panniculitis - immunology | Systemic Vasculitis - physiopathology | Panniculitis - etiology | Gastrointestinal Microbiome | Systemic Vasculitis - immunology | Intestinal Mucosa - microbiology | Enteritis - physiopathology | Obesity - metabolism | Animals | Enteritis - etiology | Models, Biological | Enteritis - microbiology | Myositis - microbiology | Enteritis - immunology | Panniculitis - physiopathology | Myositis - physiopathology | Adipose tissues | Microbiota (Symbiotic organisms) | Gastrointestinal system | Muscles | Development and progression | Insulin resistance
Journal Article
American Journal of Physiology - Heart and Circulatory Physiology, ISSN 0363-6135, 09/2012, Volume 303, Issue 6, pp. H672 - H679
Donato AJ, Henson GD, Morgan RG, Enz RA, Walker AE, Lesniewski LA. TNF-alpha impairs endothelial function in adipose tissue resistance arteries of mice with... 
Obesity | Visceral adipose tissue | Tumor necrosis factor | High-fat feeding | Endothelium | endothelium | BETA-ADRENERGIC STIMULATION | METABOLIC SYNDROME | OXIDATIVE STRESS | CARDIAC & CARDIOVASCULAR SYSTEMS | PHYSIOLOGY | SKELETAL-MUSCLE ARTERIOLES | VASCULAR DYSFUNCTION | BLOOD-FLOW | high-fat feeding | SODIUM-NITROPRUSSIDE | tumor necrosis factor | INSULIN-RESISTANCE | INFLAMMATION | NITRIC-OXIDE | PERIPHERAL VASCULAR DISEASE | obesity | visceral adipose tissue | Tumor Necrosis Factor-alpha - metabolism | Adipose Tissue, White - blood supply | Obesity - immunology | Tumor Necrosis Factor-alpha - blood | Arteries - immunology | Nitric Oxide Synthase - antagonists & inhibitors | Endothelium, Vascular - drug effects | Male | Glucose Intolerance - immunology | Obesity - blood | Dose-Response Relationship, Drug | Diet, High-Fat | Inflammation Mediators - metabolism | Obesity - etiology | Panniculitis - immunology | Glucose Intolerance - physiopathology | Macrophages - immunology | Disease Models, Animal | Endothelium, Vascular - immunology | Recombinant Proteins - metabolism | Vascular Resistance | Vasodilator Agents - pharmacology | Endothelium, Vascular - physiopathology | Enzyme Inhibitors - pharmacology | Insulin Resistance | Antibodies, Neutralizing - pharmacology | Obesity - physiopathology | Phenotype | Animals | Endothelium, Vascular - metabolism | Arteries - physiopathology | Panniculitis - physiopathology | Mice | Nitric Oxide Synthase - metabolism | Vasodilation - drug effects | Nitric Oxide - metabolism | Tumor Necrosis Factor-alpha - antagonists & inhibitors | Vascular Biology and Microcirculation
Journal Article
Circulation Research, ISSN 0009-7330, 09/2010, Volume 107, Issue 5, pp. 650 - 658
Journal Article
The Journal of Nutritional Biochemistry, ISSN 0955-2863, 10/2017, Volume 48, pp. 74 - 82
Journal Article
Journal of the American Academy of Dermatology, ISSN 0190-9622, 2014, Volume 72, Issue 4, pp. 628 - 633
Journal Article
Nature Reviews. Drug Discovery, ISSN 1474-1776, 2012, Volume 11, Issue 8, pp. 633 - 652
Journal Article