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American Journal of Agricultural Economics, ISSN 0002-9092, 01/2012, Volume 94, Issue 2, pp. 800 - 814
Journal Article
PLoS ONE, ISSN 1932-6203, 09/2015, Volume 10, Issue 9, p. e0138605
Obesity has been shown to impair myocardial performance. Some factors have been suggested as responsible for possible cardiac abnormalities in models of... 
RAT CARDIOMYOCYTES | PHOSPHOLAMBAN PHOSPHORYLATION | HIGH-FAT-DIET | INSULIN-RESISTANCE | MULTIDISCIPLINARY SCIENCES | CYCLASE ACTIVITY | CONTRACTILE RESPONSE | LEFT-VENTRICULAR MASS | SYSTOLIC FUNCTION | FAILING HEARTS | UP-REGULATION | GTP-Binding Protein alpha Subunits, Gs - metabolism | Heart - physiopathology | Adiposity - drug effects | Calcium - pharmacology | Rats, Wistar | Adrenergic beta-Agonists - pharmacology | Diet, High-Fat - adverse effects | Myocardial Contraction - drug effects | Male | Obesity - physiopathology | Blotting, Western | Obesity - metabolism | Papillary Muscles - physiopathology | Animals | Signal Transduction - drug effects | Time Factors | Isoproterenol - pharmacology | Heart - drug effects | Obesity - etiology | Papillary Muscles - metabolism | Blood Pressure - drug effects | Papillary Muscles - drug effects | Receptors, Adrenergic, beta - metabolism | Heart | Phosphorylation | Adipose tissue | Calcium | Impairment | Isoproterenol | Heart function | Kinases | Contraction | High fat diet | Proteins | Signal transduction | Receptors | Rodents | Blood pressure | Cardiology | Physical education | Heart diseases | Obesity | Carbohydrates | Cardiac muscle | Abnormalities | Muscles | Rats | Cardiomyocytes | Fatty acids | Medicine | Signaling | Diet | Diabetes | Laboratory animals | Calcium (extracellular) | Calcium ions
Journal Article
British Journal of Pharmacology, ISSN 0007-1188, 10/2013, Volume 170, Issue 4, pp. 768 - 778
Journal Article
Journal Article
Journal Article
Cardiovascular Drugs and Therapy, ISSN 0920-3206, 4/2018, Volume 32, Issue 2, pp. 169 - 173
Antazoline is a first-generation antihistaminic agent with additional anticholinergic properties and antiarrhythmic potential. Recent data shows its high... 
Antazoline | Antiarrhythmic drug | Medicine & Public Health | Electrophysiological study | Cardiology | FIBRILLATION | PHARMACOLOGICAL AGENTS | CARDIAC & CARDIOVASCULAR SYSTEMS | EFFICACY | SAFETY | CARDIOVERSION | VERNAKALANT | PHARMACOLOGY & PHARMACY | ANTIARRHYTHMIC PROPERTIES | TERMINATION | Heart Atria - drug effects | Humans | Middle Aged | Catheter Ablation | Male | Papillary Muscles - surgery | Tachycardia, Atrioventricular Nodal Reentry - surgery | Dose-Response Relationship, Drug | Young Adult | Heart Rate - drug effects | Adult | Female | Heart Atria - physiopathology | Action Potentials - drug effects | Heart Conduction System - surgery | Tachycardia, Atrioventricular Nodal Reentry - drug therapy | Tachycardia, Atrioventricular Nodal Reentry - diagnosis | Antazoline - administration & dosage | Treatment Outcome | Heart Conduction System - drug effects | Anti-Arrhythmia Agents - administration & dosage | Atrial Flutter - physiopathology | Tachycardia, Atrioventricular Nodal Reentry - physiopathology | Heart Atria - surgery | Papillary Muscles - physiopathology | Heart Conduction System - physiopathology | Atrial Flutter - diagnosis | Atrial Flutter - drug therapy | Aged | Papillary Muscles - drug effects | Atrial Flutter - surgery | Heart | Antiallergic agents | Analysis | Atrial fibrillation | Anti-arrhythmia drugs | Intervals | Conduction | Atrium | Parameters | Arrhythmia | Cardiac muscle | Muscles | Rhythm | Event-related potentials | Males | Ablation | Patients | Reduction | Sinuses | Fibrillation | Restoration | Refractory period | Reagents | Acetylcholine receptors | Electrocardiography | In vivo methods and tests | Prolongation | Original
Journal Article
Journal of the American College of Cardiology, ISSN 0735-1097, 09/2017, Volume 70, Issue 10, pp. 1232 - 1244
After myocardial infarction (MI), mitral valve (MV) tethering stimulates adaptive leaflet growth, but counterproductive leaflet thickening and fibrosis augment... 
endothelial-to-mesenchymal transition | ischemic mitral regurgitation | TGF-β | VCAM-1 | losartan | CD45 | CARDIAC-VALVE | CARDIAC & CARDIOVASCULAR SYSTEMS | NECROSIS-FACTOR-ALPHA | ANGIOTENSIN-II | TGF-beta | GROWTH-FACTOR-BETA | TO-MESENCHYMAL TRANSITION | CONVERTING ENZYME-INHIBITION | ENDOTHELIAL-CELLS | CARDIOVASCULAR-DISEASES | COMPENSATORY MECHANISM | Endothelial Cells - metabolism | Humans | Losartan - pharmacology | Echocardiography, Three-Dimensional | Angiotensin II Type 1 Receptor Blockers - pharmacology | Mitral Valve Insufficiency - diagnosis | Papillary Muscles - diagnostic imaging | Myocardial Infarction - complications | Ventricular Remodeling | Animals | Myocardial Infarction - drug therapy | Mitral Valve - diagnostic imaging | Mitral Valve - drug effects | Fibrosis | Myocardial Infarction - physiopathology | Sheep | Mitral Valve Insufficiency - etiology | Endothelial Cells - pathology | Papillary Muscles - drug effects | Mitral Valve Insufficiency - physiopathology | Transforming Growth Factor beta - metabolism | Disease Models, Animal | Heart valve diseases | Bone morphogenetic proteins | Transforming growth factors | Heart attack | Stem cells | Analysis | Endothelium | Myocardial infarction | Cell proliferation | Flow cytometry | Vascular cell adhesion molecule 1 | Heart attacks | Mesenchyme | Smooth muscle | In vitro testing | Vascularization | Cell adhesion molecules | Cell activation | Histopathology | Ischemia | Actin | Cell adhesion | Fibroblasts | Blood pressure | Cardiology | Growth factors | Heart diseases | Heart failure | Enzymes | Mitral valve | Echocardiography | Endothelial cells | Hemopoiesis | Cytometry | Molecular modelling | Collagen | Infarction | Ventricle
Journal Article
PLoS ONE, ISSN 1932-6203, 05/2017, Volume 12, Issue 5, p. e0177469
Hibernators have a distinctive ability to adapt to seasonal changes of body temperature in a range between 37 degrees C and near freezing, exhibiting, among... 
CARDIAC SARCOPLASMIC-RETICULUM | CAPACITATIVE CALCIUM-ENTRY | TRPC CHANNELS | 2-AMINOETHOXYDIPHENYL BORATE | FOOD-RESTRICTED RATS | GROUND-SQUIRREL | MULTIDISCIPLINARY SCIENCES | RAT VENTRICULAR MYOCYTES | LOW-TEMPERATURE | FORCE-FREQUENCY-RELATIONSHIP | 2-AMINOETHYLDIPHENYL BORATE | Sarcoplasmic Reticulum Calcium-Transporting ATPases - metabolism | Temperature | Calcium - metabolism | Cells, Cultured | Myocardial Contraction - drug effects | Rats | Male | Rats, Sprague-Dawley | Sciuridae - metabolism | Gene Expression Regulation - drug effects | Sciuridae - physiology | Animals | Signal Transduction - drug effects | Hibernation | Papillary Muscles - physiology | Indoles - pharmacology | Sarcoplasmic Reticulum - metabolism | Papillary Muscles - drug effects | Heart | Regulations | Arrhythmia | Freezing | Loads (forces) | Proteins | Winter | Temperature effects | Freezing point | Sensors | Activation energy | Low temperature | Cardiac muscle | Violence | Body temperature | Diseases | Blood circulation | Annual variations | Myocardium | Electrochemistry | Hypoxia | Hemodynamics | Calcium (extracellular) | Hypothermia | Viscosity | Polyethylenes | Oxidative stress | Membranes | Calcium | Science | Homeostasis | Homology | Antagonists | Heart function | Tissues | Contraction | Ca2+-transporting ATPase | Seasonal variations | Control | Rodents | Arousal | Ion channels | Excitation | Heart diseases | Food | Automation | Calcium channels | Calcium (intracellular) | Diabetes mellitus | Muscles | Ion transport | Cardiomyocytes | Environmental factors | Pharmacology | Biophysics | Sympathetic nervous system | Ventricle | Acidosis | Apoptosis
Journal Article
American Journal of Physiology - Heart and Circulatory Physiology, ISSN 0363-6135, 2015, Volume 309, Issue 11, pp. H1936 - H1946
We investigated cardiac contractility in the ACTC E361G transgenic mouse model of dilated cardiomyopathy (DCM). No differences in cardiac dimensions or... 
Dobutamine | Heart muscle contractility | Dilated cardiomyopathy | Angiotensin II stress | MOUSE PAPILLARY-MUSCLE | PRESSURE-OVERLOAD | CARDIAC & CARDIOVASCULAR SYSTEMS | PHYSIOLOGY | C57BL/6J MICE | PHOSPHORYLATION | HEART-FAILURE | MODEL | angiotensin II stress | TROPONIN-I | heart muscle contractility | ACTIN EXPRESSION | PERIPHERAL VASCULAR DISEASE | dobutamine | SKELETAL | dilated cardiomyopathy | TRANSGENIC MICE | Phosphorylation | Age Factors | Calcium - metabolism | Myocardial Contraction - drug effects | Adrenergic beta-1 Receptor Agonists - pharmacology | Ventricular Dysfunction, Left - chemically induced | Actins - genetics | Mice, Inbred CBA | Papillary Muscles - metabolism | Angiotensin II | Cardiomyopathy, Dilated - chemically induced | Disease Models, Animal | Cardiomyopathy, Dilated - genetics | Excitation Contraction Coupling - drug effects | Genetic Predisposition to Disease | Mice, Inbred C57BL | Ventricular Function, Left - drug effects | Ventricular Pressure - drug effects | Mice, Transgenic | Cardiotonic Agents - pharmacology | Cardiomyopathy, Dilated - metabolism | Dobutamine - pharmacology | Ventricular Dysfunction, Left - physiopathology | Ventricular Dysfunction, Left - metabolism | Papillary Muscles - physiopathology | Phenotype | Animals | Cardiomyopathy, Dilated - physiopathology | Mutation | Papillary Muscles - drug effects | Troponin I - metabolism | Genetic aspects | Stress (Psychology) | Analysis | Cardiomyopathy, Dilated | Angiotensin | Heart | Gene mutations | Observations | Health aspects | Contraction | Muscle Mechanics and Ventricular Function
Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 07/2017, Volume 12, Issue 7, p. e0180103
Background In the diabetic heart the beta-adrenergic response is altered partly by down-regulation of the beta 1-adrenoceptor, reducing its positive inotropic... 
MORTALITY | STIMULATION | MYOCARDIAL-INFARCTION |