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1. Full Text Oropharyngeal squamous cell carcinomas differentially express granzyme inhibitors
by van Kempen, Pauline M W and Noorlag, Rob and Swartz, Justin E and Bovenschen, Niels and Braunius, Weibel W and Vermeulen, Jeroen F and Van Cann, Ellen M and Grolman, Wilko and Willems, Stefan M
Cancer Immunology Immunotherapy, ISSN 0340-7004, 2016, Volume 65, Issue 5, pp. 575 - 85
Immunohistochemistry | Oropharyngeal Neoplasms/immunology | Multivariate Analysis | Papillomaviridae/immunology | Serpins/biosynthesis | Humans | Middle Aged | Kaplan-Meier Estimate | Male | CD3 Complex/immunology | Lymphocytes, Tumor-Infiltrating/immunology | Papillomavirus Infections/immunology | CD8-Positive T-Lymphocytes/immunology | Host-Pathogen Interactions/immunology | Antigens, Neoplasm/biosynthesis | CD4-Positive T-Lymphocytes/immunology | Aged, 80 and over | Carcinoma, Squamous Cell/immunology | Adult | Female | Aged | Oropharynx squamous cell carcinoma | Human papillomavirus | Immunology | Medicine & Public Health | Tumor microenvironment | Tumor-infiltrating lymphocytes | Oncology | Cancer Research | Granzyme inhibitors | Life Sciences & Biomedicine | Science & Technology | Oropharyngeal Neoplasms - immunology | Carcinoma, Squamous Cell - metabolism | Carcinoma, Squamous Cell - virology | Antigens, Neoplasm - biosynthesis | Host-Pathogen Interactions - immunology | CD4-Positive T-Lymphocytes - immunology | Serpins - biosynthesis | Papillomaviridae - immunology | CD8-Positive T-Lymphocytes - metabolism | Papillomavirus Infections - immunology | Lymphocytes, Tumor-Infiltrating - metabolism | Papillomavirus Infections - virology | Papillomaviridae - physiology | Antigens, Neoplasm - immunology | CD4-Positive T-Lymphocytes - metabolism | Oropharyngeal Neoplasms - virology | CD3 Complex - metabolism | Carcinoma, Squamous Cell - immunology | Serpins - immunology | Papillomavirus Infections - metabolism | CD3 Complex - immunology | Oropharyngeal Neoplasms - metabolism | CD8-Positive T-Lymphocytes - immunology | Lymphocytes, Tumor-Infiltrating - immunology | Squamous cell carcinoma | Chemotherapy | Analysis | Resveratrol | T cells | Papillomavirus infections | Cancer | Index Medicus | Original
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2. Full Text Two Listeria monocytogenes Vaccine Vectors That Express Different Molecular Forms of Human Papilloma Virus-16 (HPV-16) E7 Induce Qualitatively Different T Cell Immunity That Correlates with Their Ability to Induce Regression of Established Tumors Immortalized by HPV-16
by Gunn, George R and Zubair, Abba and Peters, Christian and Pan, Zhen-Kun and Wu, Tzyy-Choou and Paterson, Yvonne
The Journal of immunology (1950), ISSN 0022-1767, 12/2001, Volume 167, Issue 11, pp. 6471 - 6479
Life Sciences & Biomedicine | Immunology | Science & Technology | Spleen - immunology | Bacterial Vaccines - genetics | Humans | Papillomavirus E7 Proteins | Listeria monocytogenes - immunology | Vaccines, Synthetic - immunology | Papillomaviridae - genetics | Cancer Vaccines - genetics | Tumor Cells, Cultured - pathology | Heat-Shock Proteins - genetics | Lymphocyte Activation - genetics | Papillomaviridae - immunology | Tumor Cells, Cultured - virology | Bacterial Toxins | Listeria monocytogenes - metabolism | Oncogene Proteins, Viral - genetics | Epitopes, T-Lymphocyte - immunology | Cell Line, Transformed - immunology | Oncogene Proteins, Viral - metabolism | Papillomavirus Vaccines | Cell Line, Transformed - virology | T-Lymphocytes, Cytotoxic - immunology | Transforming Growth Factor beta - immunology | Cytotoxicity, Immunologic - genetics | Tumor Cells, Cultured - immunology | Genetic Vectors - immunology | Antineoplastic Agents - immunology | Hemolysin Proteins | Genetic Vectors - chemical synthesis | Mice, Inbred C57BL | Vaccines, Synthetic - genetics | Interferon-gamma - physiology | Spleen - cytology | Gene Expression Regulation, Viral - immunology | Oncogene Proteins, Viral - biosynthesis | Heat-Shock Proteins - immunology | Cell Line, Transformed - pathology | Cancer Vaccines - immunology | Animals | Bacterial Vaccines - immunology | CD4-Positive T-Lymphocytes - transplantation | Listeria monocytogenes - genetics | Mice | Oncogene Proteins, Viral - immunology | CD8-Positive T-Lymphocytes - immunology | Transforming Growth Factor beta - metabolism | E7 protein | AE7 protein | Index Medicus | Abridged Index Medicus
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3. Full Text Established Human Papillomavirus Type 16-Expressing Tumors Are Effectively Eradicated Following Vaccination with Long Peptides
by Zwaveling, Sander and Mota, Sandra C. Ferreira and Nouta, Jan and Johnson, Mark and Lipford, Grayson B and Offringa, Rienk and van der Burg, Sjoerd H and Melief, Cornelis J. M
The Journal of immunology (1950), ISSN 0022-1767, 07/2002, Volume 169, Issue 1, pp. 350 - 358
Life Sciences & Biomedicine | Immunology | Science & Technology | Oncogene Proteins, Viral - administration & dosage | Oligodeoxyribonucleotides - administration & dosage | Adjuvants, Immunologic - administration & dosage | Dendritic Cells - immunology | Humans | Molecular Sequence Data | Papillomavirus E7 Proteins | Th1 Cells - immunology | CD4-Positive T-Lymphocytes - immunology | Lymphocyte Activation - immunology | Papillomaviridae - immunology | CD40 Antigens - metabolism | CD40 Ligand - metabolism | Immunization, Secondary | Injections, Subcutaneous | Peptide Fragments - immunology | Tumor Virus Infections - immunology | Papillomavirus Infections - immunology | Epitopes, T-Lymphocyte - immunology | Tumor Cells, Cultured | Dendritic Cells - metabolism | Disease Models, Animal | Amino Acid Sequence | Oligodeoxyribonucleotides - immunology | Mice, Inbred C57BL | Peptide Fragments - administration & dosage | Cells, Cultured | Vaccines, Subunit - immunology | Oncogene Proteins, Viral - biosynthesis | Tumor Virus Infections - prevention & control | Mice, Knockout | Viral Vaccines - administration & dosage | Animals | Histocompatibility Antigens Class II - immunology | Papillomavirus Infections - prevention & control | Vaccines, Subunit - administration & dosage | Mice | Oncogene Proteins, Viral - immunology | CD8-Positive T-Lymphocytes - immunology | Viral Vaccines - immunology | Cell Line, Transformed | Index Medicus | Abridged Index Medicus
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4. Full Text A beneficial tumor microenvironment in oropharyngeal squamous cell carcinoma is characterized by a high T cell and low IL-17+ cell frequency
by Punt, Simone and nkers, Emilie and Welters, M and Goedemans, Renske and Koljenović, Senada and Bloemena, Elisabeth and Snijders, Peter and Gorter, Arko and Burg, Sjoerd and Baatenburg de Jong, Robert Jan and Jordanova, Ekaterina S
Cancer Immunology, Immunotherapy: other biological response modifications, ISSN 0340-7004, 04/2016, Volume 65, Issue 4, pp. 393 - 403
Head and neck cancer | Th17 cell | Tumor microenvironment | T cell | IL-17 | Treg | Oncology | Immunology | Life Sciences & Biomedicine | Science & Technology | Forkhead Transcription Factors - immunology | Oropharyngeal Neoplasms - immunology | T-Lymphocytes, Regulatory - metabolism | Humans | Middle Aged | Interleukin-17 - immunology | Male | T-Lymphocytes, Regulatory - immunology | Papillomaviridae - immunology | T-Lymphocytes - metabolism | Th17 Cells - metabolism | Forkhead Transcription Factors - metabolism | Aged, 80 and over | Papillomavirus Infections - immunology | Adult | Female | Papillomavirus Infections - virology | Granulocytes - metabolism | Papillomavirus Infections - complications | Kaplan-Meier Estimate | CD3 Complex - metabolism | Carcinoma, Squamous Cell - immunology | Oropharyngeal Neoplasms - complications | Tumor Microenvironment - immunology | Interleukin-17 - metabolism | Microscopy, Confocal | Carcinoma, Squamous Cell - complications | CD3 Complex - immunology | Lymphocyte Count | Th17 Cells - immunology | T-Lymphocytes - immunology | Aged | Granulocytes - immunology | Index Medicus | Original
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5. Full Text A placebo-controlled randomized HPV16 synthetic long-peptide vaccination study in women with high-grade cervical squamous intraepithelial lesions
by van Steenwijk, P.J.D and Ramwadhdoebe, T.H and Lowik, M.J.G and van der Minne, C.E and Berends-van der Meer, D and Fathers, L.M and Valentijn, A.R.P.M and Oostendorp, J and Fleuren, G.J and Hellebrekers, B.W.J and Welters, M.J.P and van Poelgeest, M.I and Melief, C.J.M and Kenter, G.G and van der Burg, S.H
Cancer Immunology and Immunotherapy, ISSN 0340-7004, 2012, Volume 61, Issue 9, pp. 1485 - 1492
Immunology | Medicine & Public Health | Immunotherapy | Vaccination | Oncology | Cancer Research | HSIL | HPV16 | Life Sciences & Biomedicine | Science & Technology | Gynecology. Andrology. Obstetrics | Pharmacology. Drug treatments | Biological and medical sciences | Medical sciences | Antineoplastic agents | Female genital diseases | Tumors | Uterine Cervical Dysplasia - therapy | Papillomavirus Vaccines - therapeutic use | Humans | Papillomavirus E7 Proteins - immunology | Uterine Cervical Neoplasms - immunology | Hypersensitivity, Delayed - immunology | Cervical Intraepithelial Neoplasia - virology | Papillomavirus Infections - therapy | Uterine Cervical Dysplasia - immunology | Cancer Vaccines - immunology | Cancer Vaccines - therapeutic use | Papillomaviridae - immunology | Cervical Intraepithelial Neoplasia - therapy | Repressor Proteins - immunology | Papillomavirus Infections - immunology | Uterine Cervical Neoplasms - virology | Female | Papillomavirus Vaccines - immunology | T-Lymphocytes - immunology | Oncogene Proteins, Viral - immunology | Cervical Intraepithelial Neoplasia - immunology | Uterine Cervical Neoplasms - therapy | Index Medicus | Short Communication
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6. Full Text CD8+ and CD4+ tumour infiltrating lymphocytes in relation to human papillomavirus status and clinical outcome in tonsillar and base of tongue squamous cell carcinoma
by Nordfors, Cecilia and Grün, Nathalie and Tertipis, Nikolaos and Ährlund-Richter, Andreas and Haeggblom, Linnea and Sivars, Lars and Du, Juan and Nyberg, Tommy and Marklund, Linda and Munck-Wikland, Eva and Näsman, Anders and Ramqvist, Torbjörn and Dalianis, Tina
European journal of cancer (1990), ISSN 0959-8049, 2013, Volume 49, Issue 11, pp. 2522 - 2530
Hematology, Oncology and Palliative Medicine | CD8+ TILs | Clinical outcome | Base of tongue cancer | CD4+ TILs | Tonsillar cancer | HPV | CD4 | CD8 | TILs | Life Sciences & Biomedicine | Oncology | Science & Technology | Biological and medical sciences | Multiple tumors. Solid tumors. Tumors in childhood (general aspects) | Medical sciences | Pharmacology. Drug treatments | Tumors | Head and Neck Neoplasms - virology | Carcinoma, Squamous Cell - pathology | Carcinoma, Squamous Cell - virology | Humans | Middle Aged | Male | Tonsillar Neoplasms - immunology | CD4-Positive T-Lymphocytes - immunology | Papillomaviridae - immunology | Squamous Cell Carcinoma of Head and Neck | Tongue Neoplasms - virology | Aged, 80 and over | Papillomavirus Infections - immunology | Adult | Female | Papillomavirus Infections - virology | Tonsillar Neoplasms - therapy | Tonsillar Neoplasms - pathology | Tongue Neoplasms - therapy | Head and Neck Neoplasms - therapy | Carcinoma, Squamous Cell - therapy | Treatment Outcome | Papillomaviridae - isolation & purification | Carcinoma, Squamous Cell - immunology | Tongue Neoplasms - pathology | Head and Neck Neoplasms - pathology | Head and Neck Neoplasms - immunology | Pilot Projects | Tonsillar Neoplasms - virology | Aged | Tongue Neoplasms - immunology | CD8-Positive T-Lymphocytes - immunology | Biomarkers, Tumor - immunology | Lymphocytes, Tumor-Infiltrating - immunology | CD4 antigen | Index Medicus | Medicin och hälsovetenskap
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7. Full Text Papillomavirus-Like Particles Induce Acute Activation of Dendritic Cells
by Lenz, Petra and Day, Patricia M and Pang, Yuk-Ying S and Frye, Stephan A and Jensen, Peter N and Lowy, Douglas R and Schiller, John T
The Journal of immunology (1950), ISSN 0022-1767, 05/2001, Volume 166, Issue 9, pp. 5346 - 5355
Life Sciences & Biomedicine | Immunology | Science & Technology | JC Virus - immunology | Dendritic Cells - immunology | Humans | Interphase - immunology | Th1 Cells - immunology | Papillomaviridae - genetics | Th1 Cells - virology | Lymphocyte Activation - immunology | Papillomaviridae - immunology | Cattle | Virus Assembly - genetics | Inflammation Mediators - metabolism | Oncogene Proteins, Viral - genetics | Capsid - metabolism | Dendritic Cells - virology | Dendritic Cells - metabolism | Oncogene Proteins, Viral - metabolism | Virion - immunology | Cytokines - metabolism | Mice, Inbred C57BL | Cells, Cultured | Immunophenotyping | Protein Binding - immunology | BK Virus - immunology | Capsid - immunology | Cell Differentiation - immunology | Animals | Virus Assembly - immunology | Capsid Proteins | Bovine papillomavirus 1 - immunology | Mice | Oncogene Proteins, Viral - immunology | Human papillomavirus 16 | Index Medicus | Abridged Index Medicus
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8. Full Text Developments in L2-based human papillomavirus (HPV) vaccines
by Schellenbacher, Christina and Roden, Richard B.S and Kirnbauer, Reinhard
Virus research, ISSN 0168-1702, 03/2017, Volume 231, pp. 166 - 175
HPV infection and disease | Human papillomavirus (HPV) vaccine | Squamous cell cancer (SCC) | Cutaneous and anogenital warts (condylomata) | Minor capsid protein (L2) | Cervical cancer (CxCa) | Life Sciences & Biomedicine | Science & Technology | Virology | Immunogenicity, Vaccine | Recombinant Fusion Proteins - immunology | Head and Neck Neoplasms - virology | Oncogene Proteins, Viral - chemistry | Papillomaviridae - drug effects | Humans | Vaccination | Cross Protection | Papillomavirus Vaccines - biosynthesis | Uterine Cervical Neoplasms - pathology | Epitopes - immunology | Papillomavirus Infections - pathology | Papillomaviridae - immunology | Capsid Proteins - chemistry | Vaccines, Virus-Like Particle | Capsid Proteins - immunology | Papillomavirus Infections - immunology | Female | Oncogene Proteins, Viral - genetics | Papillomavirus Infections - virology | Papillomavirus Vaccines - administration & dosage | Antibodies, Viral - biosynthesis | Head and Neck Neoplasms - prevention & control | Papillomaviridae - growth & development | Cancer Vaccines - administration & dosage | Cancer Vaccines - biosynthesis | Uterine Cervical Neoplasms - prevention & control | Uterine Cervical Neoplasms - immunology | Vaccines, Subunit - immunology | Recombinant Fusion Proteins - chemistry | Head and Neck Neoplasms - pathology | Papillomaviridae - pathogenicity | Cancer Vaccines - immunology | Head and Neck Neoplasms - immunology | Animals | Vaccines, Subunit - biosynthesis | Antibodies, Neutralizing - biosynthesis | Papillomavirus Infections - prevention & control | Vaccines, Subunit - administration & dosage | Immunity, Humoral - drug effects | Recombinant Fusion Proteins - genetics | Uterine Cervical Neoplasms - virology | Papillomavirus Vaccines - immunology | Epitopes - chemistry | Mice | Oncogene Proteins, Viral - immunology | Capsid Proteins - genetics | Prevention | Vaccines | Viral proteins | Health aspects | Papillomavirus infections | Wildlife conservation | Peptides | Development and progression | Papillomaviruses | Warts | Sexually transmitted diseases | Analysis | Skin | Cervical cancer | Antigenic determinants | Index Medicus | Human Papillomavirus (HPV) Vaccine | Cervical Cancer (CxCa) | Minor Capsid Protein (L2) | Squamous Cell Cancer (SCC) | cutaneous and anogenital warts (condylomata)
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9. Full Text Lipidated L2 epitope repeats fused with a single-chain antibody fragment targeting human FcγRI elicited cross-neutralizing antibodies against a broad spectrum of human papillomavirus types
by Zhang, Ting and Liu, Hongyang and Chen, Xue and Wang, Zhirong and Wang, Shuo and Qu, Chunfeng and Zhang, Jingzhi and Xu, Xuemei
Vaccine, ISSN 0264-410X, 2016, Volume 34, Issue 46, pp. 5531 - 5539
Allergy and Immunology | Papillomavirus | hFcγRI targeting | Lipoprotein | Immunology | Life Sciences & Biomedicine | Medicine, Research & Experimental | Science & Technology | Research & Experimental Medicine | Immunogenicity, Vaccine | Oncogene Proteins, Viral - administration & dosage | Papillomaviridae - chemistry | Oncogene Proteins, Viral - chemistry | Capsid Proteins - administration & dosage | Humans | Cross Protection | Receptors, IgG - immunology | Epitopes - immunology | Antibodies, Neutralizing - immunology | Papillomaviridae - immunology | Animals | Immunoglobulin Fc Fragments - immunology | Antibodies, Neutralizing - biosynthesis | Papillomavirus Infections - prevention & control | Capsid Proteins - chemistry | Capsid Proteins - immunology | Papillomavirus Infections - immunology | Papillomavirus Vaccines - immunology | Vaccines, Virus-Like Particle - immunology | Mice | Mice, Inbred BALB C | Oncogene Proteins, Viral - immunology | Papillomavirus Vaccines - administration & dosage | Index Medicus
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