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Journal Article
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 2017, Volume 292, Issue 44, pp. 18290 - 18302
Strain SYK-6 of the bacterium Sphingobium sp. catabolizes lignin-derived biphenyl via a meta-cleavage pathway. In this pathway, LigY is proposed to catalyze... 
CATABOLISM | ACID | EPSILON-SEMIALDEHYDE DECARBOXYLASE | BIOCHEMISTRY & MOLECULAR BIOLOGY | C BOND HYDROLASE | CRYSTAL-STRUCTURES | metalloenzyme | meta-cleavage | amidohydrolase superfamily | bacterial metabolism | GENE | BPHD | hydrolase | LIGNIN-RELATED BIPHENYL | DEGRADATION | lignin degradation | CATALYTIC MECHANISM | zinc | C-C hydrolase | aromatic compound | Hydrolases - genetics | Zinc - metabolism | Bacterial Proteins - chemistry | Substrate Specificity | Apoenzymes - classification | Crystallography, X-Ray | Phylogeny | Parabens - metabolism | Vanillic Acid - analogs & derivatives | Apoenzymes - metabolism | Caproates - metabolism | Hydrolases - classification | Binding Sites | Amidohydrolases - metabolism | Hydrolases - metabolism | Recombinant Proteins - metabolism | Biocatalysis | Mutagenesis, Site-Directed | Amidohydrolases - genetics | Bacterial Proteins - genetics | Models, Molecular | Recombinant Proteins - chemistry | Vanillic Acid - metabolism | Amidohydrolases - chemistry | Recombinant Proteins - classification | Hydrolysis | Sequence Homology, Amino Acid | Sphingomonadaceae - enzymology | Apoenzymes - genetics | Phthalic Acids - metabolism | Apoenzymes - chemistry | Bacterial Proteins - metabolism | Ligands | Protein Conformation | Bacterial Proteins - classification | Glutarates - metabolism | Hydrolases - chemistry | Structural Homology, Protein | Mutation | Amidohydrolases - classification | Amino Acid Substitution | Enzymology
Journal Article
British Journal of Nutrition, ISSN 0007-1145, 7/2009, Volume 102, Issue 2, pp. 201 - 206
Oligomers and polymers of flavan-3-ols (proanthocyanidins) are very abundant in the Mediterranean diet, but are poorly absorbed. However, when these... 
TNF-α | IL-1β | Microbial metabolism | IL-6 | Phenolic acids | Atherosclerosis | TNF-alpha | URINARY-EXCRETION | IL-1 beta | NECROSIS-FACTOR-ALPHA | FLAVONOIDS | MONOLAYERS | TRANSEPITHELIAL TRANSPORT | IN-VITRO | POLYPHENOLS | NUTRITION & DIETETICS | CAFFEIC ACID | EXPRESSION | Propionates - pharmacology | Propionates - metabolism | 3,4-Dihydroxyphenylacetic Acid - pharmacology | Humans | Depression, Chemical | Caffeic Acids - pharmacology | Male | Anti-Inflammatory Agents - metabolism | Parabens - metabolism | Hippurates - metabolism | Leukocytes, Mononuclear - immunology | Polyphenols | Adult | Female | Flavonoids - pharmacology | Phenols - pharmacology | Interleukin-1beta - secretion | Bacteria - metabolism | Hippurates - pharmacology | 3,4-Dihydroxyphenylacetic Acid - metabolism | Leukocytes, Mononuclear - drug effects | Anti-Inflammatory Agents - pharmacology | Tumor Necrosis Factor-alpha - secretion | Cells, Cultured | Cytokines - secretion | Phenylacetates - metabolism | Phenols - metabolism | Interleukin-6 - secretion | Parabens - pharmacology | Flavonoids - metabolism | Lipopolysaccharides - pharmacology | Caffeic Acids - metabolism | Phenylacetates - pharmacology | Leucòcits | Fenols | Leucocytes | Flavonoids | Citoquines | Antiinflammatory agents | Cytokines | Phenols | Bacteria | Bacteris | Flavonoides | Agents antiinflamatoris
Journal Article
Journal of Bacteriology, ISSN 0021-9193, 03/2008, Volume 190, Issue 5, pp. 1620 - 1630
Journal Article
Archives of Toxicology, ISSN 0340-5761, 11/2016, Volume 90, Issue 11, pp. 2699 - 2709
Journal Article
Environmental Pollution, ISSN 0269-7491, 08/2019, Volume 251, pp. 137 - 145
Maternal exposure to phthalates may cause some adverse health effects on both mother and fetus, but variations of phthalate exposure and metabolism during... 
Variations | Phthalate metabolism | Repeated measurement analysis | Chinese pregnant women | TEMPORAL VARIABILITY | PRENATAL EXPOSURE | DI(2-ETHYLHEXYL) PHTHALATE | CHILDREN | ENVIRONMENTAL SCIENCES | URINARY CONCENTRATIONS | PREDICTORS | ESTERS | PREGNANT-WOMEN | BISPHENOL-A | PARABENS | Pregnancy | Esters | Metabolites | Pregnant women | Analysis | Index Medicus
Journal Article
Journal Article
Science, ISSN 0036-8075, 3/2012, Volume 335, Issue 6072, pp. 1110 - 1114
The sulfonamide antibiotics inhibit dihydropteroate synthase (DHPS), a key enzyme in the folate pathway of bacteria and primitive eukaryotes. However,... 
Molecules | Enzymes | Antibacterials | Active sites | Pterins | REPORTS | Crystals | Diphosphates | Catalysis | Drug resistance | Crystal structure | MECHANISM | RECOGNITION | CRYSTAL-STRUCTURE | MULTIDISCIPLINARY SCIENCES | SULFONAMIDE | STAPHYLOCOCCUS-AUREUS | INHIBITORS | FARNESYLPYROPHOSPHATE SYNTHETASE | TRIMETHOPRIM-SULFAMETHOXAZOLE | Diphosphates - metabolism | Models, Chemical | Dihydropteroate Synthase - genetics | Sulfathiazoles - pharmacology | Drug Resistance, Bacterial | Molecular Sequence Data | Crystallography, X-Ray | Bacillus anthracis - enzymology | Parabens - metabolism | Anti-Bacterial Agents - chemistry | Yersinia pestis - drug effects | Sulfathiazoles - chemistry | Bacillus anthracis - drug effects | Sulfamethoxazole - metabolism | Amino Acid Sequence | Catalytic Domain | Biocatalysis | 4-Aminobenzoic Acid - chemistry | Crystallization | Models, Molecular | Sulfathiazoles - metabolism | Anti-Bacterial Agents - metabolism | Sulfamethoxazole - chemistry | Diphosphates - chemistry | Magnesium - chemistry | Mutagenesis | Sulfamethoxazole - pharmacology | Dihydropteroate Synthase - chemistry | Parabens - chemistry | Protein Conformation | Anti-Bacterial Agents - pharmacology | Dihydropteroate Synthase - metabolism | 4-Aminobenzoic Acid - metabolism | Yersinia pestis - enzymology | Drug resistance in microorganisms | Research | Properties | Sulfonamides | Health aspects | Bacteria | Mutation | Antibiotics | Index Medicus | CATALYSIS | REACTION KINETICS | ANTIBIOTICS | BACTERIA | MUTAGENESIS | PTERIDINES | ENZYMES | SUBSTRATES | SULFONAMIDES | MUTATIONS | 60 APPLIED LIFE SCIENCES | RESIDUES
Journal Article