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International Journal of Molecular Sciences, ISSN 1422-0067, 10/2019, Volume 20, Issue 20, p. 5075
Rapid reconstruction of genome-scale protein–protein interaction (PPI) networks is instrumental in understanding the cellular processes and disease... 
protein–protein interaction | paralog/ortholog | negative data sampling | machine learning | l2-regularized logistic regression
Journal Article
Genetics, ISSN 0016-6731, 12/2019, Volume 213, Issue 4, pp. 1301 - 1316
Gene duplications increase organismal robustness by providing freedom for gene divergence or by increasing gene dosage. The yeast histone chaperones Fpr3 and... 
paralog | nucleolus | chromatin | histone chaperone | genetic interactions | Investigations
Journal Article
Veterinary Parasitology, ISSN 0304-4017, 02/2019, Volume 266, pp. 103 - 110
Canine babesiosis caused by sensu stricto became an emerging disease of dogs across Europe calling for attention also in countries where it was an only rare... 
Genotype | 18S rDNA paralog | Cytb | Babesia canis | COI | MOLECULAR CHARACTERIZATION | THEILERIA | GEOGRAPHICAL-DISTRIBUTION | DERMACENTOR-RETICULATUS | 18S rDNA paralog | DNA | DOGS | SEQUENCE | VETERINARY SCIENCES | RIBOSOMAL-RNA GENE | DIFFERENTIATION | PCR | PARASITOLOGY | Genetic aspects | Cytochrome b | Phylogeny | Analysis | Genomics
Journal Article
Briefings in Bioinformatics, ISSN 1467-5463, 9/2011, Volume 12, Issue 5, pp. 379 - 391
Journal Article
Molecular biology and evolution, ISSN 0737-4038, 12/2017, Volume 34, Issue 12, pp. 3089 - 3098
Gene duplication is thought to play a major role in phenotypic evolution. Yet the forces involved in the functional divergence of young duplicate genes remain... 
subfunctionalization | duplicate genes | functional evolution | neofunctionalization | paralogs | Discoveries
Journal Article
Small GTPases, ISSN 2154-1248, 2018, p. 1
We examined sequence conservation and signatures of selection in Rab7 proteins across 11 Paramecium aurelia species, and determined the localization patterns... 
paralog | Rab7 | ortholog | protein evolution | Paramecium | phagosome | effector | lysosome | RILP
Journal Article
Nucleic acids research, ISSN 0305-1048, 2015, Volume 43, Issue 1, pp. W78 - W84
Genome wide analysis of orthologous clusters is an important component of comparative genomics studies. Identifying the overlap among orthologous clusters can... 
ORGANISMS | DIAGRAMS | LISTS | FAMILIES | BIOCHEMISTRY & MOLECULAR BIOLOGY | PARALOGS | PROTEINS | BLAST | SOFTWARE | Sequence Analysis, Protein | Multigene Family | Animals | Genomics | Molecular Sequence Annotation | Software | Genome, Plant | Internet | Phylogeny | Cluster Analysis | Web Server issue
Journal Article
Current Protocols in Bioinformatics, ISSN 1934-3396, 2011, Volume 6, Issue 35, pp. 6.12.1 - 19
OrthoMCL is an algorithm for grouping proteins into ortholog groups based on their sequence similarity. OrthoMCL-DB is a public database that allows users to... 
Reciprocal best hits | Markov clustering | MCL | Paralog | Proteome | Ortholog groups | OrthoMCL | Proteins - genetics | Computational Biology - methods | Proteome - genetics | Algorithms | Species Specificity | Databases, Genetic | Proteome - classification | Proteins - classification | Software
Journal Article
Annual Review of Genetics, ISSN 0066-4197, 2005, Volume 39, Issue 1, pp. 309 - 338
Journal Article
Journal of Theoretical Biology, ISSN 0022-5193, 07/2019, Volume 472, pp. 54 - 66
The phylogenetic trees of genes and the species which they belong to are similar, but distinct due to various evolutionary processes which affect genes but do... 
Gene loss | Recombination | Phylogenetic network | Gene duplication | Paralog exchange | Reconciliation | EVOLUTION | BIOLOGY | MATHEMATICAL & COMPUTATIONAL BIOLOGY | DUPLICATION | ALGORITHMS | LINEAGE | Biotechnology | Anopheles | Algorithms | Phylogeny | Genes | Analysis
Journal Article
Virology, ISSN 0042-6822, 04/2019, Volume 530, pp. 65 - 74
The eukaryotic translation elongation factor 1A (eEF1A) has two cell-type specific paralogs, eEF1A1 and eEF1A2. Both paralogs undertake a canonical function in... 
HIV-1 | Reverses transcription | Paralog | HEK 293T cell | eEF1A | Replication | Human primary skeletal muscle cell | CELLS | ELONGATION-FACTOR 1A | RNA | COMPLEXES | VIROLOGY | INTERACTS | IMMUNODEFICIENCY-VIRUS TYPE-1 | INFECTION | PROTEINS | EXPRESSION
Journal Article
Archives of Biochemistry and Biophysics, ISSN 0003-9861, 02/2019, Volume 662, pp. 121 - 128
Multigene families such as chemokines arose as a result of gene duplication events, followed by mutations and selection. GRO chemokines are three duplicated... 
Molecular evolution | Paralog proteins | 8-Anilinonaphthalene-1-sulfonic acid | Growth related oncogene chemokines | CXCL3 | BIOCHEMISTRY & MOLECULAR BIOLOGY | IDENTIFICATION | MAGNESIUM | EVOLUTION | BIOPHYSICS | FLUORESCENCE | SITES | CONSTRAINTS | RECEPTORS | PROTEINS
Journal Article
Nature Reviews Genetics, ISSN 1471-0056, 05/2013, Volume 14, Issue 5, pp. 360 - 366
Orthologues and paralogues are types of homologous genes that are related by speciation or duplication, respectively. Orthologous genes are generally assumed... 
Phenotype | Animals | Humans | Models, Animal | Models, Genetic | Phylogeny | Sequence Analysis | Genomics - methods | Evolution, Molecular | PROTEIN | CONSERVATION | COMPARATIVE GENOMICS | ENZYMES | PARALOGS | GENETICS & HEREDITY | CLASSIFICATION | IDENTIFICATION | HOMOLOGY | BLAST | QUEST | Usage | Evolutionary biology | Comparative analysis | Genomics
Journal Article