Arteriosclerosis, Thrombosis, and Vascular Biology, ISSN 1079-5642, 04/2005, Volume 25, Issue 4, pp. 854 - 860
OBJECTIVE—The antioxidant properties of high-density lipoprotein (HDL) have been attributed to paraoxonase (PON) enzyme activity. Human scavenger receptor...
Scavenger receptor class B type 1 | CD36 and lysosomal integral membrane protein-II analogous-1 | Paraoxonase | Arylesterase | Polymorphism | HUMAN SERUM PARAOXONASE | MAJOR CARRIER | SR-BI | scavenger receptor class B type 1 | LIPID HYDROPEROXIDES | polymorphism | GENE POLYMORPHISMS | INHIBITS 3 | HIGH-DENSITY-LIPOPROTEIN | arylesterase | FACTOR-ACETYLHYDROLASE | PERIPHERAL VASCULAR DISEASE | CHOLESTEROL ESTERS | PLATELET-ACTIVATING-FACTOR | HEMATOLOGY | paraoxonase | Scavenger Receptors, Class B | Exons | Humans | Middle Aged | Coronary Disease - epidemiology | Male | Genetic Variation | Coronary Disease - metabolism | CD36 Antigens | Adult | Female | Genetic Predisposition to Disease - epidemiology | Gene Expression | Cholesterol, HDL - metabolism | Risk Factors | Genotype | RNA Stability | Aryldialkylphosphatase - genetics | Aryldialkylphosphatase - metabolism | Polymorphism, Genetic | Phenotype | Receptors, Scavenger | Coronary Disease - genetics | Alleles | Cholesterol, LDL - metabolism | Sex Distribution | Receptors, Immunologic - genetics | Receptors, Immunologic - metabolism
Scavenger receptor class B type 1 | CD36 and lysosomal integral membrane protein-II analogous-1 | Paraoxonase | Arylesterase | Polymorphism | HUMAN SERUM PARAOXONASE | MAJOR CARRIER | SR-BI | scavenger receptor class B type 1 | LIPID HYDROPEROXIDES | polymorphism | GENE POLYMORPHISMS | INHIBITS 3 | HIGH-DENSITY-LIPOPROTEIN | arylesterase | FACTOR-ACETYLHYDROLASE | PERIPHERAL VASCULAR DISEASE | CHOLESTEROL ESTERS | PLATELET-ACTIVATING-FACTOR | HEMATOLOGY | paraoxonase | Scavenger Receptors, Class B | Exons | Humans | Middle Aged | Coronary Disease - epidemiology | Male | Genetic Variation | Coronary Disease - metabolism | CD36 Antigens | Adult | Female | Genetic Predisposition to Disease - epidemiology | Gene Expression | Cholesterol, HDL - metabolism | Risk Factors | Genotype | RNA Stability | Aryldialkylphosphatase - genetics | Aryldialkylphosphatase - metabolism | Polymorphism, Genetic | Phenotype | Receptors, Scavenger | Coronary Disease - genetics | Alleles | Cholesterol, LDL - metabolism | Sex Distribution | Receptors, Immunologic - genetics | Receptors, Immunologic - metabolism
Journal Article
Journal of Clinical Lipidology, ISSN 1933-2874, 2014, Volume 8, Issue 3, pp. 249 - 255
Background Only a few studies have focused on the possible modulatory role of paraoxonase 1 (PON1) polymorphisms in lipid profiles, especially in children and...
Cardiovascular | Lipid disorders | Paraoxonase 1 activity | Type 1 diabetes | Paraoxonase 1 polymorphisms | Cardiovascular risk | Keywords | ATHEROSCLEROSIS | RISK | GENE-CLUSTER POLYMORPHISMS | MELLITUS | SERUM PARAOXONASE | PON1 GENE | PLASMA-LIPOPROTEINS | PHARMACOLOGY & PHARMACY | CORONARY-HEART-DISEASE | ASSOCIATION | ARTERY-DISEASE | Haplotypes | Apolipoproteins - metabolism | Gene Frequency | Humans | Diabetes Mellitus, Type 1 - genetics | Spectrometry, Fluorescence | Genotype | Male | Cholesterol - metabolism | Aryldialkylphosphatase - genetics | Aryldialkylphosphatase - metabolism | Polymorphism, Genetic | Young Adult | Lipid Metabolism Disorders - genetics | Adolescent | Adult | Female | Child | Tunisia
Cardiovascular | Lipid disorders | Paraoxonase 1 activity | Type 1 diabetes | Paraoxonase 1 polymorphisms | Cardiovascular risk | Keywords | ATHEROSCLEROSIS | RISK | GENE-CLUSTER POLYMORPHISMS | MELLITUS | SERUM PARAOXONASE | PON1 GENE | PLASMA-LIPOPROTEINS | PHARMACOLOGY & PHARMACY | CORONARY-HEART-DISEASE | ASSOCIATION | ARTERY-DISEASE | Haplotypes | Apolipoproteins - metabolism | Gene Frequency | Humans | Diabetes Mellitus, Type 1 - genetics | Spectrometry, Fluorescence | Genotype | Male | Cholesterol - metabolism | Aryldialkylphosphatase - genetics | Aryldialkylphosphatase - metabolism | Polymorphism, Genetic | Young Adult | Lipid Metabolism Disorders - genetics | Adolescent | Adult | Female | Child | Tunisia
Journal Article
Atherosclerosis, ISSN 0021-9150, 12/2017, Volume 267, pp. 99 - 109
Type 1 diabetes (T1D) is a chronic autoimmune disease characterized by absence of insulin secretion due to destruction of the pancreatic beta-cells. Patients...
HDL functionality | Anti-inflammatory activity | Anti-oxidant activity | Type 1 diabetes | Cholesterol efflux | FAMILIAL HYPERCHOLESTEROLEMIA | CARDIAC & CARDIOVASCULAR SYSTEMS | LIPID-METABOLISM | TRANSFER PROTEIN-ACTIVITY | CHOLESTERYL ESTER TRANSFER | ACUTE CORONARY SYNDROME | PARAOXONASE ACTIVITY | HIGH-DENSITY-LIPOPROTEIN | ACUTE-PHASE RESPONSE | SERUM PARAOXONASE | CARDIOVASCULAR-DISEASE | PERIPHERAL VASCULAR DISEASE | Prevalence | Antioxidants - chemistry | Cardiovascular Diseases - metabolism | Diabetes Mellitus, Type 1 - physiopathology | Humans | Risk Factors | Diabetes Mellitus, Type 1 - complications | Cholesterol - metabolism | Diabetes Mellitus, Type 2 - blood | Insulin - metabolism | Insulin-Secreting Cells - metabolism | Animals | Anti-Inflammatory Agents - chemistry | Diabetes Mellitus, Type 1 - blood | Cholesterol, HDL - blood | Dyslipidemias - metabolism | Mice | Diabetes Mellitus, Type 2 - complications | Pancreatic beta cells | Chronic kidney failure | Low density lipoproteins | Diabetic nephropathies | Blood lipids | Risk factors
HDL functionality | Anti-inflammatory activity | Anti-oxidant activity | Type 1 diabetes | Cholesterol efflux | FAMILIAL HYPERCHOLESTEROLEMIA | CARDIAC & CARDIOVASCULAR SYSTEMS | LIPID-METABOLISM | TRANSFER PROTEIN-ACTIVITY | CHOLESTERYL ESTER TRANSFER | ACUTE CORONARY SYNDROME | PARAOXONASE ACTIVITY | HIGH-DENSITY-LIPOPROTEIN | ACUTE-PHASE RESPONSE | SERUM PARAOXONASE | CARDIOVASCULAR-DISEASE | PERIPHERAL VASCULAR DISEASE | Prevalence | Antioxidants - chemistry | Cardiovascular Diseases - metabolism | Diabetes Mellitus, Type 1 - physiopathology | Humans | Risk Factors | Diabetes Mellitus, Type 1 - complications | Cholesterol - metabolism | Diabetes Mellitus, Type 2 - blood | Insulin - metabolism | Insulin-Secreting Cells - metabolism | Animals | Anti-Inflammatory Agents - chemistry | Diabetes Mellitus, Type 1 - blood | Cholesterol, HDL - blood | Dyslipidemias - metabolism | Mice | Diabetes Mellitus, Type 2 - complications | Pancreatic beta cells | Chronic kidney failure | Low density lipoproteins | Diabetic nephropathies | Blood lipids | Risk factors
Journal Article
Arthritis & Rheumatology, ISSN 2326-5191, 08/2018, Volume 70, Issue 8, pp. 1240 - 1250
Objective To compare the activity of high‐density lipoprotein (HDL)–associated paraoxonase 1 (PON1) in patients with psoriasis (PsO) and patients with...
INTIMA-MEDIA THICKNESS | RHEUMATOID-ARTHRITIS | ANTIBODIES | INDIVIDUALS | MYELOPEROXIDASE | ARYLESTERASE ACTIVITIES | SERUM PARAOXONASE | ATHEROSCLEROSIS | POLYMORPHISM | RHEUMATOLOGY | APOLIPOPROTEIN-A-I | Aryldialkylphosphatase - blood | Severity of Illness Index | Blood Sedimentation | Cardiovascular Diseases - etiology | Arthritis, Psoriatic - enzymology | Lipoproteins, HDL - blood | Humans | Middle Aged | Risk Factors | Male | Inflammation | Cardiovascular Diseases - enzymology | Psoriasis - complications | Carboxylic Ester Hydrolases - blood | Arthritis, Psoriatic - complications | Arthritis, Psoriatic - blood | Adult | Female | Psoriasis - enzymology | C-Reactive Protein - analysis | Psoriasis - blood | Arylesterase | Dyslipidemia | Paraoxonase 1 | Arthritis | Density | Risk factors | Proteins | Body mass index | Soil testing | Red blood cells | Lipoproteins (high density) | Hypertension | Psoriasis | Diabetes mellitus | Health risks | Paraoxonase | Risk analysis | Joint diseases | E.S.R | Sedimentation | Patients | Quality of life | Laboratory tests | Serum levels | Body mass | Body size | Cardiovascular diseases | Health risk assessment | Metabolic disorders | Smoking
INTIMA-MEDIA THICKNESS | RHEUMATOID-ARTHRITIS | ANTIBODIES | INDIVIDUALS | MYELOPEROXIDASE | ARYLESTERASE ACTIVITIES | SERUM PARAOXONASE | ATHEROSCLEROSIS | POLYMORPHISM | RHEUMATOLOGY | APOLIPOPROTEIN-A-I | Aryldialkylphosphatase - blood | Severity of Illness Index | Blood Sedimentation | Cardiovascular Diseases - etiology | Arthritis, Psoriatic - enzymology | Lipoproteins, HDL - blood | Humans | Middle Aged | Risk Factors | Male | Inflammation | Cardiovascular Diseases - enzymology | Psoriasis - complications | Carboxylic Ester Hydrolases - blood | Arthritis, Psoriatic - complications | Arthritis, Psoriatic - blood | Adult | Female | Psoriasis - enzymology | C-Reactive Protein - analysis | Psoriasis - blood | Arylesterase | Dyslipidemia | Paraoxonase 1 | Arthritis | Density | Risk factors | Proteins | Body mass index | Soil testing | Red blood cells | Lipoproteins (high density) | Hypertension | Psoriasis | Diabetes mellitus | Health risks | Paraoxonase | Risk analysis | Joint diseases | E.S.R | Sedimentation | Patients | Quality of life | Laboratory tests | Serum levels | Body mass | Body size | Cardiovascular diseases | Health risk assessment | Metabolic disorders | Smoking
Journal Article
Toxicology and Applied Pharmacology, ISSN 0041-008X, 2009, Volume 235, Issue 1, pp. 1 - 9
Paraoxonase 1 (PON1) hydrolyzes a number of organophosphorus (OP) compounds including insecticides and nerve agents. The efficacy of PON1 to protect against a...
PON1 polymorphism | Chlorpyrifos | Pharmacogenetics | Paraoxonase 1 | Diazoxon | Chlorpyrifos oxon | Diazinon | CHLORPYRIFOS OXON | TOXICITY | Chlorpyrifos axon | ARYLESTERASE | GENE | Q192R POLYMORPHISM | PHARMACOLOGY & PHARMACY | HUMAN-SERUM PARAOXONASE | TOXICOLOGY | CORONARY-HEART-DISEASE | PROMOTER | MOLECULAR-BASIS | EXPRESSION | Chlorpyrifos - analogs & derivatives | Isoenzymes | Humans | Substrate Specificity | Aryldialkylphosphatase - genetics | Aryldialkylphosphatase - metabolism | Organophosphorus Compounds - metabolism | Polymorphism, Genetic | Chlorpyrifos - metabolism | Gene Expression Regulation, Enzymologic | Hydrolysis | Insecticides - metabolism | Molecular Structure | Enzymes | Enzyme inhibitors | War use | Analysis | Medical genetics | Gases, Asphyxiating and poisonous | Index Medicus | HYDROLYSIS | IN VIVO | 60 APPLIED LIFE SCIENCES | ENZYMES | SUBSTRATES | PARATHION
PON1 polymorphism | Chlorpyrifos | Pharmacogenetics | Paraoxonase 1 | Diazoxon | Chlorpyrifos oxon | Diazinon | CHLORPYRIFOS OXON | TOXICITY | Chlorpyrifos axon | ARYLESTERASE | GENE | Q192R POLYMORPHISM | PHARMACOLOGY & PHARMACY | HUMAN-SERUM PARAOXONASE | TOXICOLOGY | CORONARY-HEART-DISEASE | PROMOTER | MOLECULAR-BASIS | EXPRESSION | Chlorpyrifos - analogs & derivatives | Isoenzymes | Humans | Substrate Specificity | Aryldialkylphosphatase - genetics | Aryldialkylphosphatase - metabolism | Organophosphorus Compounds - metabolism | Polymorphism, Genetic | Chlorpyrifos - metabolism | Gene Expression Regulation, Enzymologic | Hydrolysis | Insecticides - metabolism | Molecular Structure | Enzymes | Enzyme inhibitors | War use | Analysis | Medical genetics | Gases, Asphyxiating and poisonous | Index Medicus | HYDROLYSIS | IN VIVO | 60 APPLIED LIFE SCIENCES | ENZYMES | SUBSTRATES | PARATHION
Journal Article
Atherosclerosis, ISSN 0021-9150, 2013, Volume 228, Issue 2, pp. 353 - 361
Abstract Objectives Paraoxonase 1 (PON1) was suggested to play an anti-inflammatory role. In the present study we questioned whether PON1 has a direct impact...
Cardiovascular | M1 activation | Inflammation | Paraoxonase 1 (PON1) | Macrophages | Atherosclerosis | CELLS | OXIDATIVE STRESS | ACTIVATION | LACTONASE ACTIVITY | MECHANISM | MEMBRANE | HIGH-AFFINITY | DENSITY-LIPOPROTEIN | PERIPHERAL VASCULAR DISEASE | TRANSGENIC MICE | Tumor Necrosis Factor-alpha - metabolism | Inflammation - pathology | Reactive Oxygen Species - metabolism | Oxidative Stress | Humans | Interferon-gamma - metabolism | Necrosis | Inflammation Mediators - metabolism | Interleukin-6 - metabolism | Macrophages - immunology | Cell Line | Macrophages - pathology | Mice, Inbred C57BL | Mice, Transgenic | Inflammation - immunology | Aryldialkylphosphatase - genetics | Aryldialkylphosphatase - metabolism | Macrophages - enzymology | Phenotype | Animals | Lipopolysaccharides - pharmacology | Inflammation - genetics | Macrophages - drug effects | Inflammation - prevention & control | Mice | Scavenger Receptors, Class B - metabolism | Macrophage Activation - drug effects | Inflammation - enzymology | Phagocytosis
Cardiovascular | M1 activation | Inflammation | Paraoxonase 1 (PON1) | Macrophages | Atherosclerosis | CELLS | OXIDATIVE STRESS | ACTIVATION | LACTONASE ACTIVITY | MECHANISM | MEMBRANE | HIGH-AFFINITY | DENSITY-LIPOPROTEIN | PERIPHERAL VASCULAR DISEASE | TRANSGENIC MICE | Tumor Necrosis Factor-alpha - metabolism | Inflammation - pathology | Reactive Oxygen Species - metabolism | Oxidative Stress | Humans | Interferon-gamma - metabolism | Necrosis | Inflammation Mediators - metabolism | Interleukin-6 - metabolism | Macrophages - immunology | Cell Line | Macrophages - pathology | Mice, Inbred C57BL | Mice, Transgenic | Inflammation - immunology | Aryldialkylphosphatase - genetics | Aryldialkylphosphatase - metabolism | Macrophages - enzymology | Phenotype | Animals | Lipopolysaccharides - pharmacology | Inflammation - genetics | Macrophages - drug effects | Inflammation - prevention & control | Mice | Scavenger Receptors, Class B - metabolism | Macrophage Activation - drug effects | Inflammation - enzymology | Phagocytosis
Journal Article
7.
Paraoxonase 1 Gene L55M Polymorphism and Paraoxonase 1 Activity in Obstructive Sleep Apnea Patients
2019, Advances in Experimental Medicine and Biology, Volume 1150, 8
The antioxidant enzyme paraoxonase-1 (PON1) may limit oxidative stress in the development of cardiovascular diseases (CVD) and obstructive sleep apnea (OSA)....
MEDICINE, RESEARCH & EXPERIMENTAL | Oxidative stress | MYOCARDIAL-INFARCTION | Antioxidant activity | PON1 | Paraoxonase enzyme | RISK | HEALTHY | Gene polymorphism | Obstructive sleep apnea | ENDOTHELIAL FUNCTION | SERUM PARAOXONASE | Q192R | RESPIRATORY SYSTEM | Atherosclerosis | DISEASE | BIOLOGY | STRESS | ASSOCIATION
MEDICINE, RESEARCH & EXPERIMENTAL | Oxidative stress | MYOCARDIAL-INFARCTION | Antioxidant activity | PON1 | Paraoxonase enzyme | RISK | HEALTHY | Gene polymorphism | Obstructive sleep apnea | ENDOTHELIAL FUNCTION | SERUM PARAOXONASE | Q192R | RESPIRATORY SYSTEM | Atherosclerosis | DISEASE | BIOLOGY | STRESS | ASSOCIATION
Book Chapter
Arteriosclerosis, Thrombosis, and Vascular Biology, ISSN 1079-5642, 07/2019, Volume 39, Issue 7, pp. 1483 - 1491
OBJECTIVE—Albuminuria is an important risk factor for cardiovascular disease in diabetes mellitus. We determined whether albuminuria associates with...
atherosclerosis | KIDNEY-DISEASE | COMPLICATIONS TRIAL/EPIDEMIOLOGY | proteomics | RISK | triglycerides | GENE POLYMORPHISMS | albuminuria | HEART-DISEASE | INTERVENTIONS | SERUM PARAOXONASE | kidney diseases | INFLAMMATION | CARDIOVASCULAR-DISEASE | PERIPHERAL VASCULAR DISEASE | HDL CHOLESTEROL | HEMATOLOGY | lipoproteins
atherosclerosis | KIDNEY-DISEASE | COMPLICATIONS TRIAL/EPIDEMIOLOGY | proteomics | RISK | triglycerides | GENE POLYMORPHISMS | albuminuria | HEART-DISEASE | INTERVENTIONS | SERUM PARAOXONASE | kidney diseases | INFLAMMATION | CARDIOVASCULAR-DISEASE | PERIPHERAL VASCULAR DISEASE | HDL CHOLESTEROL | HEMATOLOGY | lipoproteins
Journal Article
JAMA, ISSN 0098-7484, 03/2008, Volume 299, Issue 11, pp. 1265 - 1276
CONTEXT Paraoxonase 1 (PON1) is reported to have antioxidant and cardioprotective properties. The relationship between PON1 genotypes and functional activity...
LIPOPROTEIN | MEDICINE, GENERAL & INTERNAL | METAANALYSIS | PROTEIN | SERUM PARAOXONASE | ATHEROSCLEROSIS | MICE | CORONARY-HEART-DISEASE | ASSOCIATION | GENOME | ARTERY-DISEASE | Aryldialkylphosphatase - blood | Prognosis | Prospective Studies | Humans | Middle Aged | Oxidative Stress - physiology | Risk Factors | Proportional Hazards Models | Logistic Models | Male | Chromatography, High Pressure Liquid | Aryldialkylphosphatase - genetics | Cardiovascular Diseases - genetics | Polymorphism, Genetic | Tandem Mass Spectrometry | Polymerase Chain Reaction | Cardiovascular Diseases - blood | Cardiovascular Diseases - epidemiology | Female | Aged | Fluorescence Polarization | Oxidative stress | Genetic aspects | Research | Cardiovascular diseases | Health aspects | Risk factors | Genetic polymorphisms | Antioxidants | Genetics | Cardiovascular disease | Polymorphism
LIPOPROTEIN | MEDICINE, GENERAL & INTERNAL | METAANALYSIS | PROTEIN | SERUM PARAOXONASE | ATHEROSCLEROSIS | MICE | CORONARY-HEART-DISEASE | ASSOCIATION | GENOME | ARTERY-DISEASE | Aryldialkylphosphatase - blood | Prognosis | Prospective Studies | Humans | Middle Aged | Oxidative Stress - physiology | Risk Factors | Proportional Hazards Models | Logistic Models | Male | Chromatography, High Pressure Liquid | Aryldialkylphosphatase - genetics | Cardiovascular Diseases - genetics | Polymorphism, Genetic | Tandem Mass Spectrometry | Polymerase Chain Reaction | Cardiovascular Diseases - blood | Cardiovascular Diseases - epidemiology | Female | Aged | Fluorescence Polarization | Oxidative stress | Genetic aspects | Research | Cardiovascular diseases | Health aspects | Risk factors | Genetic polymorphisms | Antioxidants | Genetics | Cardiovascular disease | Polymorphism
Journal Article
Journal of the Science of Food and Agriculture, ISSN 0022-5142, 10/2014, Volume 94, Issue 13, pp. 2752 - 2757
BACKGROUND Paraoxonase 1 (PON1) protects the oxidative modification of low‐density lipoprotein (LDL) and is a major anti‐atherosclerotic protein component of...
paraoxonase 1 | quercetin | catechin | low‐density lipoproteins | onion | oxidative stress | Oxidative stress | Catechin | Onion | Low-density lipoproteins | Paraoxonase 1 | Quercetin | ANTIOXIDANT ACTIVITY | DIETARY POLYPHENOLS | LIPID-PEROXIDATION | FOOD SCIENCE & TECHNOLOGY | ATHEROSCLEROSIS | PON1 ACTIVITY | low-density lipoproteins | IN-VITRO | SERUM PARAOXONASE | LDL | AGRICULTURE, MULTIDISCIPLINARY | GENE-EXPRESSION | MICE | CHEMISTRY, APPLIED | Aryldialkylphosphatase - blood | Up-Regulation | Oxidative Stress | Rats, Wistar | Onions - chemistry | Male | Aryldialkylphosphatase - chemistry | Onions - economics | Atherosclerosis - enzymology | Phytotherapy - adverse effects | Catechin - therapeutic use | Dietary Supplements - adverse effects | Catechin - adverse effects | Quercetin - therapeutic use | Lipoproteins, LDL - analysis | Biomarkers - blood | Random Allocation | India | Atherosclerosis - blood | Antioxidants - therapeutic use | Animals | Lipoproteins, LDL - antagonists & inhibitors | Plant Roots - chemistry | Quercetin - adverse effects | Antioxidants - adverse effects | Lipid Peroxidation | Plant Extracts - therapeutic use | Atherosclerosis - prevention & control | Plant Extracts - adverse effects | Flavonoids | Flavones | Bioflavonoids | Low density lipoproteins | Oxidation-reduction reaction | Blood lipids
paraoxonase 1 | quercetin | catechin | low‐density lipoproteins | onion | oxidative stress | Oxidative stress | Catechin | Onion | Low-density lipoproteins | Paraoxonase 1 | Quercetin | ANTIOXIDANT ACTIVITY | DIETARY POLYPHENOLS | LIPID-PEROXIDATION | FOOD SCIENCE & TECHNOLOGY | ATHEROSCLEROSIS | PON1 ACTIVITY | low-density lipoproteins | IN-VITRO | SERUM PARAOXONASE | LDL | AGRICULTURE, MULTIDISCIPLINARY | GENE-EXPRESSION | MICE | CHEMISTRY, APPLIED | Aryldialkylphosphatase - blood | Up-Regulation | Oxidative Stress | Rats, Wistar | Onions - chemistry | Male | Aryldialkylphosphatase - chemistry | Onions - economics | Atherosclerosis - enzymology | Phytotherapy - adverse effects | Catechin - therapeutic use | Dietary Supplements - adverse effects | Catechin - adverse effects | Quercetin - therapeutic use | Lipoproteins, LDL - analysis | Biomarkers - blood | Random Allocation | India | Atherosclerosis - blood | Antioxidants - therapeutic use | Animals | Lipoproteins, LDL - antagonists & inhibitors | Plant Roots - chemistry | Quercetin - adverse effects | Antioxidants - adverse effects | Lipid Peroxidation | Plant Extracts - therapeutic use | Atherosclerosis - prevention & control | Plant Extracts - adverse effects | Flavonoids | Flavones | Bioflavonoids | Low density lipoproteins | Oxidation-reduction reaction | Blood lipids
Journal Article
Biochemia Medica, ISSN 1330-0962, 06/2011, Volume 21, Issue 2, pp. 122 - 130
Journal Article
Biochemical Pharmacology, ISSN 0006-2952, 2011, Volume 81, Issue 3, pp. 337 - 344
Paraoxonase 1 (PON1) is a high density lipoprotein (HDL)-associated enzyme displaying esterase and lactonase activity. PON1 hydrolyzes several organophosphorus...
Antioxidants | Anti-diabetic drugs | Paraoxonase 1 | Polyphenols | Alcohol | Statins | Hypolipemic drugs | OXIDATIVE STRESS | PARAOXONASE/ARYLESTERASE ACTIVITIES | LIPID-PEROXIDATION | ANTIOXIDANT ENZYME | INCREASES SERUM PARAOXONASE | CHOLESTERYL ESTER TRANSFER | HIGH-DENSITY-LIPOPROTEIN | GENE-EXPRESSION | PHARMACOLOGY & PHARMACY | E-DEFICIENT MICE | APOLIPOPROTEIN-A-I | Enzyme Activators - pharmacology | Cardiovascular Diseases - prevention & control | Humans | Esterases - metabolism | Antioxidants - pharmacology | Alcohol Drinking | Hypolipidemic Agents - pharmacology | Aryldialkylphosphatase - genetics | Aryldialkylphosphatase - metabolism | Hypoglycemic Agents - pharmacology | Polymorphism, Genetic | Gene Expression Regulation, Enzymologic | Diet | Environmental Pollutants - antagonists & inhibitors | Flavonoids - pharmacology | Phenols - pharmacology | Index Medicus | alcohol | polyphenols | antioxidants | statins | anti-diabetic drugs | hypolipemic drugs
Antioxidants | Anti-diabetic drugs | Paraoxonase 1 | Polyphenols | Alcohol | Statins | Hypolipemic drugs | OXIDATIVE STRESS | PARAOXONASE/ARYLESTERASE ACTIVITIES | LIPID-PEROXIDATION | ANTIOXIDANT ENZYME | INCREASES SERUM PARAOXONASE | CHOLESTERYL ESTER TRANSFER | HIGH-DENSITY-LIPOPROTEIN | GENE-EXPRESSION | PHARMACOLOGY & PHARMACY | E-DEFICIENT MICE | APOLIPOPROTEIN-A-I | Enzyme Activators - pharmacology | Cardiovascular Diseases - prevention & control | Humans | Esterases - metabolism | Antioxidants - pharmacology | Alcohol Drinking | Hypolipidemic Agents - pharmacology | Aryldialkylphosphatase - genetics | Aryldialkylphosphatase - metabolism | Hypoglycemic Agents - pharmacology | Polymorphism, Genetic | Gene Expression Regulation, Enzymologic | Diet | Environmental Pollutants - antagonists & inhibitors | Flavonoids - pharmacology | Phenols - pharmacology | Index Medicus | alcohol | polyphenols | antioxidants | statins | anti-diabetic drugs | hypolipemic drugs
Journal Article
Journal of Affective Disorders, ISSN 0165-0327, 2014, Volume 159, pp. 23 - 30
Abstract Background Major depression and bipolar disorder are accompanied by the activation of immune-inflammatory and Oxidative and Nitrosative Stress (O&NS)...
Psychiatry | Oxidative stress | Depression | Bipolar disorder | Inflammation | Paraoxonase | Cytokines | PATHWAYS | PSYCHIATRY | INTERLEUKIN-6 | CLINICAL NEUROLOGY | CIGARETTE-SMOKING | SERUM PARAOXONASE | RISK-FACTOR | SUICIDAL-BEHAVIOR | ASSOCIATION | EXPRESSION | Aryldialkylphosphatase - blood | Depressive Disorder, Major - blood | Humans | Middle Aged | Genotype | Logistic Models | Male | Smoking - genetics | Biomarkers - blood | Genetic Markers | Aryldialkylphosphatase - genetics | Bipolar Disorder - genetics | Gene-Environment Interaction | Polymorphism, Genetic | Depressive Disorder, Major - genetics | Adult | Female | Antioxidants | Medical research | Medical colleges | Genetic research | Physiological aspects | Medicine, Experimental | Genetic aspects | Major depressive disorder | Index Medicus
Psychiatry | Oxidative stress | Depression | Bipolar disorder | Inflammation | Paraoxonase | Cytokines | PATHWAYS | PSYCHIATRY | INTERLEUKIN-6 | CLINICAL NEUROLOGY | CIGARETTE-SMOKING | SERUM PARAOXONASE | RISK-FACTOR | SUICIDAL-BEHAVIOR | ASSOCIATION | EXPRESSION | Aryldialkylphosphatase - blood | Depressive Disorder, Major - blood | Humans | Middle Aged | Genotype | Logistic Models | Male | Smoking - genetics | Biomarkers - blood | Genetic Markers | Aryldialkylphosphatase - genetics | Bipolar Disorder - genetics | Gene-Environment Interaction | Polymorphism, Genetic | Depressive Disorder, Major - genetics | Adult | Female | Antioxidants | Medical research | Medical colleges | Genetic research | Physiological aspects | Medicine, Experimental | Genetic aspects | Major depressive disorder | Index Medicus
Journal Article