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Journal Article
Cellular and Molecular Life Sciences, ISSN 1420-682X, 04/2012, Volume 69, Issue 7, pp. 1153 - 1165
Journal Article
Nature Communications, ISSN 2041-1723, 2014, Volume 5, p. 4930
Journal Article
Nature Communications, ISSN 2041-1723, 12/2018, Volume 9, Issue 1, pp. 817 - 17
Neuronal loss in Parkinson's disease (PD) is associated with aberrant mitochondrial function and impaired proteostasis. Identifying the mechanisms that link... 
CIRCULAR-DICHROISM SPECTRA | DOPAMINE NEURONS | CELLS | IN-VITRO | PROTEIN SECONDARY STRUCTURE | MULTIDISCIPLINARY SCIENCES | LEWY BODY DISEASE | MITOPHAGY | NEURONAL CULTURES | AGGREGATION | PARKINSONS-DISEASE | Embryonic Stem Cells - metabolism | Neurons - pathology | Cardiolipins - pharmacology | Embryonic Stem Cells - cytology | Microtubule-Associated Proteins - genetics | Microtubule-Associated Proteins - metabolism | Humans | Male | Protein Transport - drug effects | Mitochondria - ultrastructure | Mitochondrial Membranes - drug effects | Parkinson Disease, Secondary - pathology | Protein Folding - drug effects | Parkinson Disease, Secondary - metabolism | Female | Cell Differentiation | Neurons - metabolism | alpha-Synuclein - genetics | Induced Pluripotent Stem Cells - cytology | Neurons - drug effects | Induced Pluripotent Stem Cells - metabolism | Cell Line | Gene Expression | Antibodies, Monoclonal - pharmacology | Cell Communication | Mice, Transgenic | Mitochondria - metabolism | Mitochondria - drug effects | Mitochondrial Membranes - metabolism | Animals | Parkinson Disease, Secondary - genetics | Mitochondrial Degradation - drug effects | Mitochondrial Membranes - ultrastructure | Mice | Mutation | alpha-Synuclein - metabolism | Cell culture | Membranes | Parkinson's disease | Neurodegenerative diseases | Neurons | Pathogenesis | Fibrils | Transgenic mice | Stem cell transplantation | Exposure | Synuclein | Seeding | Mutants | Pathology | Mitochondria | Rodents | Stem cells | Monoclonal antibodies | Cardiolipin | Aberration | Pluripotency | Movement disorders
Journal Article
Molecular Therapy, ISSN 1525-0016, 01/2015, Volume 23, Issue 1, pp. 17 - 23
In Parkinson's disease, α-synuclein is known to activate microglia and this activation has been proposed as one of the mechanisms of neurodegeneration. There... 
MEDICINE, RESEARCH & EXPERIMENTAL | CELLS | MICROGLIAL ACTIVATION | ALZHEIMERS-DISEASE | TAU PATHOLOGY | RAT MODEL | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | IN-VIVO | MOUSE MODEL | GENETICS & HEREDITY | CENTRAL-NERVOUS-SYSTEM | TNF-ALPHA | PARKINSONS-DISEASE | Dependovirus - genetics | Microglia - metabolism | Neurons - pathology | Tyrosine 3-Monooxygenase - metabolism | Substantia Nigra - pathology | alpha-Synuclein - antagonists & inhibitors | Chemokine CX3CL1 - metabolism | Astrocytes - pathology | Male | Substantia Nigra - metabolism | Oxidopamine | Glial Fibrillary Acidic Protein | Parkinsonian Disorders - metabolism | Antigen Presentation | Microglia - pathology | Parkinson Disease, Secondary - metabolism | Parkinsonian Disorders - genetics | Neurons - metabolism | alpha-Synuclein - genetics | Parkinson Disease, Secondary - chemically induced | Promoter Regions, Genetic | Signal Transduction | Parkinson Disease, Secondary - therapy | Gene Expression Regulation | Rats | Chemokine CX3CL1 - agonists | Chemokine CX3CL1 - genetics | Nerve Tissue Proteins - genetics | Nerve Tissue Proteins - metabolism | Tyrosine 3-Monooxygenase - genetics | Animals | Parkinson Disease, Secondary - genetics | Parkinsonian Disorders - pathology | Parkinsonian Disorders - therapy | 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine | Mice | Histocompatibility Antigens Class II - genetics | Genetic Vectors | alpha-Synuclein - metabolism | Astrocytes - metabolism | Genetic Therapy - methods | Original
Journal Article
Neurobiology of Aging, ISSN 0197-4580, 2017, Volume 53, pp. 159 - 168
Journal Article
JAMA Neurology, ISSN 2168-6149, 01/2013, Volume 70, Issue 1, pp. 20 - 24
Parkinson disease is one of the most common neurodegenerative diseases associated with aging. At least 18 genetic loci and 13 disease-related genes for... 
PI31 | MUTATIONS | INHIBITOR | FBXO7 | CLINICAL NEUROLOGY | Globus Pallidus | Parkinson Disease, Secondary - genetics | Blepharospasm - genetics | Mutation - genetics | F-Box Proteins - genetics | Humans
Journal Article
Journal Article
Experimental Neurology, ISSN 0014-4886, 05/2012, Volume 235, Issue 1, pp. 306 - 315
Development of relevant models of Parkinson's disease (PD) is essential for a better understanding of the pathological processes underlying the human disease... 
Axonopathy | Animal models | Behavioural test | Neurodegeneration | AAV | SYSTEM | LESION MODEL | MOTOR FUNCTION | SUBSTANTIA-NIGRA | NEUROSCIENCES | DOPAMINE NEURONS | OVEREXPRESSION | RECOVERY | GDNF | GENE-TRANSFER | STRIATUM | Substantia Nigra - physiopathology | Neurons - pathology | Substantia Nigra - pathology | Nerve Degeneration - physiopathology | Motor Activity - drug effects | Nerve Degeneration - genetics | Substantia Nigra - metabolism | Corpus Striatum - metabolism | Nerve Degeneration - metabolism | Medial Forebrain Bundle - physiopathology | Parkinson Disease, Secondary - pathology | Medial Forebrain Bundle - pathology | Parkinson Disease, Secondary - metabolism | Behavior, Animal - drug effects | Female | Neurons - metabolism | alpha-Synuclein - genetics | Neurons - drug effects | Corpus Striatum - pathology | Disease Models, Animal | Corpus Striatum - physiopathology | Rats | Behavior, Animal - physiology | Oxidopamine - poisoning | Rats, Sprague-Dawley | Nerve Degeneration - pathology | Motor Activity - genetics | Substantia Nigra - drug effects | Animals | Parkinson Disease, Secondary - genetics | Parkinson Disease, Secondary - physiopathology | Corpus Striatum - drug effects | Medial Forebrain Bundle - metabolism | alpha-Synuclein - metabolism | Medial forebrain bundle | Dopamine | Parkinson's disease | Neurodegenerative diseases | Neurons | Therapeutic applications | 6-Hydroxydopamine | Synuclein | Cell death | Neostriatum | Toxins | MPTP | Movement disorders | Neurologi | Clinical Medicine | Neurology | Medical and Health Sciences | Medicin och hälsovetenskap | Klinisk medicin
Journal Article
Redox Biology, ISSN 2213-2317, 04/2017, Volume 11, Issue C, pp. 1 - 11
Journal Article
PLoS Genetics, ISSN 1553-7390, 2015, Volume 11, Issue 12, p. e1005710