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Journal Article
Cellular and Molecular Life Sciences, ISSN 1420-682X, 04/2012, Volume 69, Issue 7, pp. 1153 - 1165
Journal Article
Nature Communications, ISSN 2041-1723, 12/2018, Volume 9, Issue 1, pp. 817 - 17
Neuronal loss in Parkinson's disease (PD) is associated with aberrant mitochondrial function and impaired proteostasis. Identifying the mechanisms that link... 
CIRCULAR-DICHROISM SPECTRA | DOPAMINE NEURONS | CELLS | IN-VITRO | PROTEIN SECONDARY STRUCTURE | MULTIDISCIPLINARY SCIENCES | LEWY BODY DISEASE | MITOPHAGY | NEURONAL CULTURES | AGGREGATION | PARKINSONS-DISEASE | Embryonic Stem Cells - metabolism | Neurons - pathology | Cardiolipins - pharmacology | Embryonic Stem Cells - cytology | Microtubule-Associated Proteins - genetics | Microtubule-Associated Proteins - metabolism | Humans | Male | Protein Transport - drug effects | Mitochondria - ultrastructure | Mitochondrial Membranes - drug effects | Parkinson Disease, Secondary - pathology | Protein Folding - drug effects | Parkinson Disease, Secondary - metabolism | Female | Cell Differentiation | Neurons - metabolism | alpha-Synuclein - genetics | Induced Pluripotent Stem Cells - cytology | Neurons - drug effects | Induced Pluripotent Stem Cells - metabolism | Cell Line | Gene Expression | Antibodies, Monoclonal - pharmacology | Cell Communication | Mice, Transgenic | Mitochondria - metabolism | Mitochondria - drug effects | Mitochondrial Membranes - metabolism | Animals | Parkinson Disease, Secondary - genetics | Mitochondrial Degradation - drug effects | Mitochondrial Membranes - ultrastructure | Mice | Mutation | alpha-Synuclein - metabolism | Cell culture | Membranes | Parkinson's disease | Neurodegenerative diseases | Neurons | Pathogenesis | Fibrils | Transgenic mice | Stem cell transplantation | Exposure | Synuclein | Seeding | Mutants | Pathology | Mitochondria | Rodents | Stem cells | Monoclonal antibodies | Cardiolipin | Aberration | Pluripotency | Movement disorders
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 02/2017, Volume 127, Issue 2, pp. 720 - 734
Journal Article
Scientific Reports, ISSN 2045-2322, 2012, Volume 2, Issue 1, p. 898
Journal Article
Journal of Neurochemistry, ISSN 0022-3042, 06/2015, Volume 133, Issue 5, pp. 700 - 707
Journal Article
Experimental Neurology, ISSN 0014-4886, 05/2012, Volume 235, Issue 1, pp. 306 - 315
Development of relevant models of Parkinson's disease (PD) is essential for a better understanding of the pathological processes underlying the human disease... 
Axonopathy | Animal models | Behavioural test | Neurodegeneration | AAV | SYSTEM | LESION MODEL | MOTOR FUNCTION | SUBSTANTIA-NIGRA | NEUROSCIENCES | DOPAMINE NEURONS | OVEREXPRESSION | RECOVERY | GDNF | GENE-TRANSFER | STRIATUM | Substantia Nigra - physiopathology | Neurons - pathology | Substantia Nigra - pathology | Nerve Degeneration - physiopathology | Motor Activity - drug effects | Nerve Degeneration - genetics | Substantia Nigra - metabolism | Corpus Striatum - metabolism | Nerve Degeneration - metabolism | Medial Forebrain Bundle - physiopathology | Parkinson Disease, Secondary - pathology | Medial Forebrain Bundle - pathology | Parkinson Disease, Secondary - metabolism | Behavior, Animal - drug effects | Female | Neurons - metabolism | alpha-Synuclein - genetics | Neurons - drug effects | Corpus Striatum - pathology | Disease Models, Animal | Corpus Striatum - physiopathology | Rats | Behavior, Animal - physiology | Oxidopamine - poisoning | Rats, Sprague-Dawley | Nerve Degeneration - pathology | Motor Activity - genetics | Substantia Nigra - drug effects | Animals | Parkinson Disease, Secondary - genetics | Parkinson Disease, Secondary - physiopathology | Corpus Striatum - drug effects | Medial Forebrain Bundle - metabolism | alpha-Synuclein - metabolism | Medial forebrain bundle | Dopamine | Parkinson's disease | Neurodegenerative diseases | Neurons | Therapeutic applications | 6-Hydroxydopamine | Synuclein | Cell death | Neostriatum | Toxins | MPTP | Movement disorders | Neurologi | Clinical Medicine | Neurology | Medical and Health Sciences | Medicin och hälsovetenskap | Klinisk medicin
Journal Article
Scientific Reports, ISSN 2045-2322, 12/2017, Volume 7, Issue 1, pp. 7506 - 10
Cell-to-cell spreading of misfolded alpha-synuclein (alpha-syn) is suggested to contribute to the progression of neuropathology in Parkinson's disease (PD).... 
TRANSMISSION | OLFACTORY-BULB | LRRK2 | MULTIDISCIPLINARY SCIENCES | MITOCHONDRIAL DYSFUNCTION | AUTOPHAGY | PATHOLOGY | STRESS | C. ELEGANS | AGGREGATION | PARKINSONS-DISEASE | RNA, Small Interfering - genetics | Humans | Green Fluorescent Proteins - genetics | Protein Transport - drug effects | Autophagy - drug effects | Brain - metabolism | Parkinson Disease, Secondary - pathology | Parkinson Disease, Secondary - drug therapy | Parkinson Disease, Secondary - metabolism | Neurons - metabolism | alpha-Synuclein - genetics | Autophagy - genetics | Discoidin Domain Receptor 2 - genetics | Protein-Serine-Threonine Kinases - metabolism | Disease Models, Animal | Caenorhabditis elegans - metabolism | Caenorhabditis elegans - genetics | Endocytosis - drug effects | Discoidin Domain Receptor 2 - metabolism | Ubiquitin-Protein Ligases - metabolism | Adenosine Triphosphatases - metabolism | Brain - drug effects | Adenosine Triphosphatases - antagonists & inhibitors | Brain - pathology | Adenosine Triphosphatases - genetics | Ubiquitin-Protein Ligases - genetics | Caenorhabditis elegans Proteins - genetics | RNA, Small Interfering - metabolism | Neurons - pathology | Caenorhabditis elegans Proteins - metabolism | Ubiquitin-Protein Ligases - antagonists & inhibitors | Exocytosis - drug effects | Protein-Serine-Threonine Kinases - antagonists & inhibitors | Neurons - drug effects | Genes, Reporter | Tryptophan Hydroxylase - metabolism | Protein Aggregates - drug effects | Green Fluorescent Proteins - metabolism | Gene Expression Regulation | Protein-Serine-Threonine Kinases - genetics | Cell Communication | Spectrometry, Fluorescence | Aldehyde Oxidoreductases - genetics | Sirolimus - pharmacology | Aldehyde Oxidoreductases - metabolism | Tryptophan Hydroxylase - genetics | alpha-Synuclein - chemistry | Animals | Parkinson Disease, Secondary - genetics | Caenorhabditis elegans Proteins - antagonists & inhibitors | Aldehyde Oxidoreductases - antagonists & inhibitors | alpha-Synuclein - metabolism | Endocytosis | Parkinson's disease | Neurodegenerative diseases | Life span | Protein folding | Nematodes | Synuclein | Phagocytosis | Cell spreading | Cell migration | Movement disorders
Journal Article