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Endocrinology, ISSN 0013-7227, 09/2013, Volume 154, Issue 9, pp. 3410 - 3422
We recently created a mouse model displaying precocious Sertoli cell (SC) and spermatogenic development induced by SC-specific transgenic androgen receptor expression (TgSCAR... 
Life Sciences & Biomedicine | Endocrinology & Metabolism | Science & Technology | Leydig Cells - cytology | Up-Regulation | Receptors, Transforming Growth Factor beta - genetics | Testis - metabolism | Cell Count | Receptors, Androgen - metabolism | Male | Receptors, Peptide - genetics | Isoenzymes - metabolism | Leydig Cells - metabolism | Receptors, Androgen - biosynthesis | Sertoli Cells - cytology | Sexual Development | Cell Differentiation | Receptors, Cell Surface - biosynthesis | Patched Receptors | Receptor, Platelet-Derived Growth Factor alpha - biosynthesis | Animals, Newborn | Biomarkers - metabolism | Sertoli Cells - metabolism | Receptor, Platelet-Derived Growth Factor alpha - metabolism | Testis - cytology | Testosterone Congeners - blood | Isoenzymes - genetics | Receptors, Cell Surface - metabolism | Mice, Transgenic | Receptors, Peptide - biosynthesis | Testis - growth & development | Hemizygote | Receptors, Transforming Growth Factor beta - biosynthesis | Animals | Receptors, Androgen - genetics | Receptors, Transforming Growth Factor beta - metabolism | Receptor, Platelet-Derived Growth Factor alpha - genetics | Testosterone Congeners - metabolism | Ligands | Mice | Isoenzymes - biosynthesis | Patched-1 Receptor | Receptors, Cell Surface - genetics | Receptors, Peptide - metabolism | Index Medicus | Abridged Index Medicus
Journal Article
Proceedings of the National Academy of Sciences - PNAS, ISSN 0027-8424, 3/2005, Volume 102, Issue 13, pp. 4789 - 4794
Recent studies demonstrated that stromal cells isolated from adult bone marrow have the competence of differentiating into neuronal cells in vitro and in vivo.... 
Biological Sciences | Adult stem cells | Reverse transcriptase polymerase chain reaction | Complementary DNA | Neurons | Stromal cells | Neuroglia | Sensory neurons | Neural stem cells | Pluripotent stem cells | Mesenchymal stem cells | Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Immunohistochemistry | Colforsin | Receptors, G-Protein-Coupled - metabolism | Bone Marrow Cells - physiology | Neurons - cytology | Hedgehog Proteins | Flow Cytometry | Tretinoin - metabolism | Smoothened Receptor | Membrane Proteins - metabolism | Neurons - metabolism | Trans-Activators - pharmacology | Patched Receptors | Cell Differentiation - physiology | Genes, Tumor Suppressor | Tretinoin - pharmacology | Mice, Inbred C57BL | Pluripotent Stem Cells - physiology | Receptors, Cell Surface - metabolism | Receptors, Retinoic Acid - metabolism | DNA Primers | Reverse Transcriptase Polymerase Chain Reaction | Drug Synergism | Pluripotent Stem Cells - metabolism | Animals | Cell Differentiation - drug effects | Fibroblast Growth Factor 2 | Organ of Corti - cytology | Trans-Activators - metabolism | Mice | Retinoic Acid Receptor alpha | Bone Marrow Cells - metabolism | Organ of Corti - metabolism | Developmental biology | Stem cells | Research | Index Medicus | Organ of Corti | Receptors, Cell Surface | Life Sciences | Pluripotent Stem Cells | Receptors, Retinoic Acid | Cell Differentiation | Tretinoin | Trans-Activators | Biochemistry, Molecular Biology | Receptors, G-Protein-Coupled | Membrane Proteins | Bone Marrow Cells | Forskolin | Molecular biology
Journal Article
Journal Article
Journal Article
Journal Article
Nature (London), ISSN 0028-0836, 07/2019, Volume 571, Issue 7764, pp. 284 - 288
.... Analogous to other G protein-coupled receptors, the activation of SMO is associated with subtle motions in the extracellular domain, and larger intracellular... 
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Catalytic Domain - drug effects | Sterols - metabolism | Smoothened Receptor - agonists | Hedgehog Proteins - metabolism | Smoothened Receptor - metabolism | Hedgehog Proteins - agonists | Xenopus Proteins - chemistry | Cell Membrane - chemistry | Cholesterol - chemistry | Patched-1 Receptor - metabolism | Patched-1 Receptor - antagonists & inhibitors | Cell Membrane - metabolism | Protein Stability | Binding Sites | Smoothened Receptor - antagonists & inhibitors | Sterols - pharmacology | Sterols - chemistry | Models, Molecular | Cholesterol - metabolism | Molecular Dynamics Simulation | Animals | Signal Transduction - drug effects | Biosensing Techniques | Cholesterol - pharmacology | Ligands | Protein Conformation | Mice | Single-Chain Antibodies - immunology | Smoothened Receptor - chemistry | Physiological aspects | Development and progression | Sterols | Hedgehog proteins | Tumors | Plasma | G protein-coupled receptors | Molecular dynamics | Activation | Hydrophobicity | Drug resistance | Inactivation | Proteins | Signal transduction | Receptors | Embryogenesis | Physiology | Crystal structure | Dynamic structural analysis | Deactivation | Computer simulation | Tissue engineering | Cholesterol | Patched protein | Embryonic growth stage | Regeneration | Signaling | Molecular modelling | Hedgehog protein | Medulloblastoma | Software | Mutation | Intracellular | Transporter | Binding sites | Cancer | Index Medicus
Journal Article
Journal of investigative dermatology, ISSN 0022-202X, 08/2011, Volume 131, Issue 8, pp. 1735 - 1744
Journal Article